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Published by capintec, 2015-10-13 11:17:15

CRC ® -35R Dose Calibrator Manual- Revision E

CRC-35R Manual - 9250-0054 Rev E

CRC® -35R

RADIOISOTOPE DOSE CALIBRATOR

OWNER'S MANUAL

Capintec, Inc.
Sales and Marketing

6 Arrow Road
Ramsey, NJ 07446
Phone (800) ASK-4CRC
Fax (215) 825-1336

Capintec, Inc.
Service and Customer Support

540 Alpha Drive
Pittsburgh, PA 15238
Phone (800) 227-6832
Fax (412) 963-0610

©Copyright 1993, Capintec, Inc.

CRC® is a registered trademark of Capintec, Inc.
ALL RIGHTS RESERVED

Manual Stock No. 9250-0054

Revised February 1994
Revised August 1994
Revised October 1994
Revised March 1995



CAPINTEC, INC. CRC®-35R

CRC®-35R 1-1
TABLE OF CONTENTS 1-1
1-2
1. INTRODUCTION 1-3
Unpacking Instructions 1-3
Purpose of the Calibrator 1-3
Features
System Configuration 2-1
Control by Computer 2-1
Installation 2-2
2-2
2. SPECIFICATIONS AND REQUIREMENTS
Environmental Requirements 3-1
Power Requirements 3-2
Specifications 3-2
Performance 3-3
3-3
3. GENERAL OPERATING INSTRUCTIONS
How to Enter Data 4-1
Menus and Lists 4-1
Multiple Choice Lists
Error Messages 6-1
Screen Dimmer 6-2
6-3
4. GETTING STARTED 6-4
Power-up Sequence 6-4
Preliminary Procedures 6-4
6-6
5. DEFINITION OF KEYS 6-8

6. MEASUREMENTS 7-2
Measurement Screen 7-4
Making a Measurement 7-6
Selecting a Nuclide
Selecting the Chamber
Selecting Ci or Bq
Inputting Future Time
Dispensing a Dose
Printing a Dose Table

7. Moly Assay
Mo99 Background
Mo99 Assay
Tc99m Assay

August, 94 T- 1 CONTENTS

CAPINTEC, INC. CRC®-35R

8. TESTS 8-1
Daily Test 8-2
Background 8-5
System Test 8-10
Accuracy Test 8-11
Constancy Test 8-13
Linearity Test 8-13
Standard Test 8-16
Lineator Test 8-18
Calicheck Test 8-20
Geometry Test 8-24
QC Tests 8-24
Single Strip / Single Solvent 8-25
Two Strips / Two Solvents 8-25
Tc99m HMPAO (Exametazine) 8-25
Tc99m Mertiatide (MAG3)
9-2
9. INVENTORY FUNCTIONS 9-5
Adding to Inventory 9-6
Deleting from Inventory 9-9
Withdrawing from Inventory 9-10
Dispensing to Patient
Dispensing from Inventory 10-1
10-1
10. UTILITIES 10-2
Utility Menu 10-3
Reports 10-3
Test Reports 10-3
Inventory Report 10-3
Patient Report 10-3
Nuclide List 10-4
Compound List 10-6
Reference Decay Calendar 10-7
Calculator / Ci <--> Bq 10-7
Decay Calculation 10-8
Setup 10-8
Entering Password
Hospital Name
Diagnostics

August, 94 T- 2 CONTENTS

CAPINTEC, INC. CRC®-35R

11. SETUP (TEST and RESULTS) 11-1
Ci / Bq 11-2
Reference Sources 11-2
Reference Source Menu 11-5
Additional Reference Nuclides 11-7
Nuclide Data 11-7
Additional Nuclides 11-9
Calibration Number Changes 11-12
User Key Assignments 11-14
Compound Menu 11-14
Additional Compounds 11-17
Compounds to Display 11-18
Define Tests 11-18
Linearity Tests 11-19
Standard Test 11-20
Lineator Test 11-22
Calicheck Test 11-23
Constancy Test 11-25
Parameters / User Preferences 11-25
Moly Assay Method 11-26
Allowed Variations 11-26
Calibration Test Results 11-26
Patient Dose 11-26
Mo/Tc99m 11-27
Type of Printing 11-28
Date Input Format
12-1
12. SYSTEM SETUP 12-1
Configuration Menu 12-6
Setup System Configuration 12-7
Print System Configuration 12-7
Setup Remote Nuclide List 12-8
Print Remote Nuclide List 12-9
Time / Date Setup
Hospital Name Setup

13. PRINCIPLE OF THE CALIBRATOR

August, 94 T- 3 CONTENTS

CAPINTEC, INC. CRC®-35R

14. ERROR MESSAGES 14-1
Data Entry 14-1
Date and Time Entry 14-1
Nuclide Entered 14-2
Calibration Number 14-2
Chamber Selection 14-2
Dispense Dose 14-2
Dose Table 14-2
Background 14-3
Moly Assay 14-3
Inventory 14-3
Reports 14-3
Reference Sources 14-4
Daily Test 14-4
Additional Nuclides 14-4
Compounds 14-5
Accuracy Test 14-5
Constancy Test 14-5
Geometry Test 14-6
Linearity Test 14-6
System Configuration 14-7
Remote Displays 14-7
System Errors 14-8
Device Error

SENSITIVITY CURVE
APPENDIX I: TABLE OF CALIBRATION SETTING NUMBERS
APPENDIX II: FACTORS FOR NON-EQUILIBRIUM ISOTOPES

August, 94 T- 4 CONTENTS

CAPINTEC, INC. CRC®-35R

INTRODUCTION Chapter 1

UNPACKING INSTRUCTIONS

Upon receiving your CRC®- 35R Radioisotope Dose Calibrator, verify that the shipping
carton(s) is in good condition. There should be no evidence of physical abuse or water
damage. Should the instrument be received in a damaged condition, save the shipping
carton and request an immediate inspection by the carrier. Capintec is not responsible for
damage which occurs during shipment, but will make every effort to assist you in obtaining
restitution from the carrier.

The chamber and console are packed in plastic bags. Keep the package in the room where
it will be used for 24 hours before opening the bags.

CAUTION
The chamber weighs about 15.5kg (34.25 lb.). Be careful when removing it from the carton.

The following items are located in the carton(s)
1. Manual
2. CRC®- 35R console
3. CRC®- 35R chamber assembly with attached cable
4. Chamber well liner (in the well)
5. Sample holder (in the well liner)
6. Line cord
7. Mo Assay Kit (optional)
8. Tickets
9. Printer
10. Printer Paper

PURPOSE OF THE CALIBRATOR

The Capintec Model CRC®- 35R Radioisotope Dose Calibrator provides a quick, convenient
and accurate method of measuring the activity of a radioisotope at the time and place of its
application.

When a sample of a known nuclide is placed in the chamber well and the proper nuclide is
selected, the activity of the sample will be displayed.

March, 95 1-1 INTRODUCTION

CAPINTEC, INC. CRC®-35R

FEATURES

• Computes and Displays activity at a specified future time.
• Clock and Calendar
• Automatic background Adjustment
• Ci / Bq key with lockout
• Nine preset nuclide keys
• Five user defined nuclide keys
• Selection of nuclide by name or Calibration Number
• Semi - automatic Moly Assay
• Constancy Test
• Accuracy Test
• Linearity Test using decay and sleeve methods
• Geometry Test
• Decay Calendar
• QC Test with choice of 4 protocols
• Tracking of inventory with up to 100 items
• Storage for later printout of

300 measurements
100 inventory items
120 accuracy tests

15 geometry tests
15 linearity tests
• Reference Sources -- up to 10 with duplication of isotopes.
• Ability to drive up to 8 ionization chambers
• Up to 8 remote displays possible. Each may view and control 1 chamber.
• May be interfaced to and controlled by a computer

March, 95 1-2 INTRODUCTION

CAPINTEC, INC. CRC®-35R

SYSTEM CONFIGURATION

The basic System Configuration consists of the Main Unit (display and keyboard) and one
chamber.

The system can be configured with up to 8 chambers and 8 remote displays.

Each remote display may view and control only the chamber to which it is assigned
("attached").

The Main Unit can view and control any chamber.

The user may select the chamber to be viewed and controlled by the Main Unit by pressing
the CHAMBER KEY and entering the number of the chamber.

When a chamber which is attached to a remote is selected, the word MAIN will appear on the
Remote and the Remote echoes the data displayed on the Main Unit. Conversely, the
nuclide and procedure can be chosen at the Remote and the data will be echoed on the Main
Unit.

CONTROL BY COMPUTER

The system can also be controlled by a computer via the RS232 port.

The computer can select a chamber, change the nuclide, begin the system test, and request
the reading of the selected chamber.

The protocol necessary to do this and a sample program may be obtained from
Capintec, Inc.

INSTALLATION

Installation of the Model CRC®-35R Radioisotope Dose Calibrator requires only a few easy
steps.

Basic System
1. Place the well chamber and the console on a firm level surface where they will not be

subjected to mechanical vibration.

2. Plug the connector on the cable which is attached to the chamber into the "Port B"
connector on the back of the console (See Fig. 1-1).

3. Secure the connectors by tightening the two "jack" screws.

4. Connect the printer.

March, 95 1-3 INTRODUCTION

CAPINTEC, INC. CRC®-35R

5. Plug the CRC®-35R line cord into the rear of the console and then into a suitable power
source (refer to Chapter 2).

6. Turn on the power switch on the rear of the console.

Printer
1. Unpack the printer and assemble the parts (paper separator, ribbon, line cord, etc.). Be

sure to remove any packing material from inside the printer.

2. Plug the printer cord in to a suitable source of power and turn the printer on.

3. Set the lever on the left side of the print head to the rear, and the lever on the right side
to the front.

4. Load a supply of continuous form paper (refer to the printer manual). Pull the lever on
the left forward until the paper is loaded. Return the left lever to the rear position.

5. Make sure that both the printer and the CRC®-35R are turned off.

6. Connect the printer cable to the back of the printer and to the parallel connector on the
back of the CRC®-35R console (See Fig. 1-1) and tighten the "jack" screws.

ON
OFF

PORT A PORT B PARALLEL

CAUTIONS AND NOTES [Fig. 1-1] INTRODUCTION
1-4
March, 95

CAPINTEC, INC. CRC®-35R

CAUTION
There are no internal adjustments or modifications which may be done by the user within the
conditions of the warranty, except changing the fuse. Due to the presence of high voltages,
opening the cover with the system plugged in may be hazardous. Refer all servicing to
qualified personnel.

CAUTION
Never use the calibrator without the well liner being in place. Liners are inexpensive and
easy to replace. A contaminated chamber is a very costly mistake.

CAUTION
Care must be exercised when moving the instrument or when maintenance is performed.
The shielded cylinder is heavy (15.5 kg or 34.25 lb.). In order to provide the required
sensitivity, the wall of the ionization chamber is extremely thin and the chamber is filled with
a highly pressurized gas. It is therefore, essential to avoid mechanical shock or vibration of
any kind.

CAUTION
When working with a heavy sample (especially a CapMac or Moly Assay Canister) always
lower it gently into the chamber well. Dropping any heavy object into the well can cause
permanent, expensive damage.

CAUTION
The use of multiplication and division factors in Calibration Numbers is only to maintain a
degree of consistency with other Capintec dose calibrators. The CRC®-35R is direct
reading. If multiplication or division is required, the arithmetic will be done by the system.
The actual activity is displayed. DO NOT apply these factors to the displayed activity
yourself.

CAUTION
It is desirable to leave the unit powered at all times in order to prevent absorption of moisture
and to maintain the stability of the instrument (especially if the instrument is subjected to high
humidity or low temperature).

CAUTION
The sensitivity of the chamber is somewhat dependent upon the vertical position of the
sample within the well. All calibrations were done with a Standard Sample placed in the
supplied sample holder (dipper). It should be noted that in this configuration, the sample is
not quite at the bottom of the well. If, for any reason, you make a measurement without
using the dipper, be sure that the sample is in the correct vertical position. Both the CapMac
and the Standard Moly Assay Canister maintain the same position as the dipper.

NOTE
It is recommended that the periodic (every four to five years) re-calibration of the unit be
performed by Capintec to guarantee that the instrument's high reliability is maintained.

March, 95 1-5 INTRODUCTION



CAPINTEC, INC. CRC®-35R

Chapter 2

SPECIFICATIONS AND
REQUIREMENTS

ENVIRONMENTAL REQUIREMENTS

A. The calibrator should be located in an area where the background radiation is as low and
as constant as possible.

B. Both the console and the well chamber should be located on a stable base in a clean and
dry location. The well chamber should not be subject to vibration during use.

C. Avoid locating either the console or the well chamber in direct sunlight or in close
proximity to a heater or air conditioner.

D. For maximum reliability, the system should be located where the temperature is between
10°C to 30°C (50°F to 86°F) and is reasonably constant. The relative humidity should not
exceed 80%.

NOTE
The calibrator may be used in temperatures up to 40°C (104°F) and relative humidity up to
95% so long as no condensation forms on any part of the system.

POWER REQUIREMENTS

100V (90 - 125V), 0.5A, 50/60Hz
120V (90 - 125V), 0.5A, 50/60Hz
220V (180 - 250V), 0.25A, 50/60Hz
240V (180 - 250V), 0.25A, 50/60Hz

Built-in power line filter and surge protection.

May, 94 2-1 SPECIFICATIONS

CAPINTEC, INC. CRC®-35R

SPECIFICATIONS

DIMENSIONS

Console: Height 14.9cm (5.8")
Width 27.5cm (10.8")
Depth 35.2cm (13.8")
Weight 4.4kg (9.75 lb.)

Chamber: Height 41.3cm (16.25")
Diameter 17.5cm (6.9")
Weight 15.5kg (34.25 lb.)
Cable Length1 2.0m (8 ft.)

Cables: Power 1.8m (6 ft.)
Printer 3.0 m (10 ft.)

PERFORMANCE

Maximum Activity: 370 GBq (10.0 Ci)
Resolution:
Electrometer Accuracy: .001 MBq (.01 µCi)
System Precision:
System Linearity: better than ± 1%
Response Time:
better than ±0.1% of FSD2
Repeatability:
within ±2%3

4 sec. if <20µCi

better than 2 sec. if >20µCi

within ±1%4

NOTE

The overall accuracy of a measurement may be affected by:
• The accuracy of the electrometer.
• The accuracy of the calibration number for the specific nuclide.
• The configuration of the sample and any vial or syringe correction factors.
• The accuracies of the standard sources used for calibration of the electrometer.

1Longer cables are available. Consult factory.
2Full Scale Display (2000). System precision is better than ±2 least significant digits in Bq mode.
3Linearity includes chamber response to high activity samples and electrometer range changes.
4Over a 24 hour period during which the calibrator is powered at all times.

May, 94 2-2 SPECIFICATIONS

CAPINTEC, INC. CRC®-35R

Chapter 3

GENERAL OPERATING INSTRUCTIONS

HOW TO ENTER DATA

ENTRY FIELDS
Every entry field (place to enter data) has a description which tells you what to enter.

CURSOR
The block cursor indicates where the user may input data. The cursor advances as data is
input. When the maximum number of characters have been input, the cursor will remain on
the last character.

ENTER KEY
Every data entry must be terminated by pressing ENTER. If there is more than 1 entry field
on the screen the cursor will move to the next field, otherwise it will return to the beginning of
the current field.

BSP KEY
Use the BSP key to erase the last character entered.

FUNCTION KEYS
Function keys are only active if it is the first keystroke in the field.

ARROW KEYS
If there is more than one field on the screen, the arrow keys will move the cursor to the next
field without changing the field. It must be the first keystroke in the field.

INTEGER INPUT
For fields that require integers, only the digits 0-9 are active.

FLOATING POINT (DECIMAL) INPUT
For fields that require a floating point (decimal) number, the digits 0-9 and the decimal point
are active. The decimal point is the UTIL key.

March, 95 3-1 GENERAL OPERATING INSTRUCTIONS

CAPINTEC, INC. CRC®-35R

ALPHANUMERIC INPUT
Some fields allow numbers and letters (e.g. lot #, patient ID etc.) .
When a key with numbers and letters is pressed, the number is displayed. To obtain one of
the letters on that key, press the UP or DOWN arrow. Pressing the arrows cycles through
the letters and number on that key. The cursor will not advance when the arrows are
pressed.

RANGE CHECKING
All numeric input has a valid range. If the entry is outside this range, an error message will
appear: VALUE OUT OF RANGE. Press any key to return to data entry. The cursor will be
at the end of the field. Use BSP to erase as much of the entry as needed and fix the entry.

QUESTIONS
Questions should be answered YES or NO. The UP Arrow is the YES key. The DOWN
Arrow is the NO key.

MENUS and LISTS
Menus and data lists appear in many places. The first item in the list is highlighted. Use the
arrow keys to highlight the desired menu or list choice. If there are no function keys
displayed, press ENTER to select your choice. If there are function keys, press the function
key which describes the desired action.

Some lists have function keys which do not select any item. These can be pressed when
any item is highlighted.

Lists which are longer than 1 screen have the word more after the last item on the screen.
To see the rest of the list, move the highlight to the last item and the use the DOWN arrow.
The word more will now appear at the top of the list to indicate that there are list items above
it (it will also appear below the list if the list continues past this screen).

MULTIPLE CHOICE LISTS
Some lists are used to choose more than one item. These always have function keys:

SELECT (F1) - Selects an item from the list
ALL (F2) - Selects all items in the list
DESEL (F3) - Deselects the highlighted items
DONE (F4) - Exits the screen

In the lists, a # sign appears in front of the items that have been selected.

March, 95 3-2 GENERAL OPERATING INSTRUCTIONS

CAPINTEC, INC. CRC®-35R

ERROR MESSAGES
Error messages appear at the bottom of the screen in a box.
After reading the message, press any key to erase the message and restore whatever was
previously in the region of the error message.

SCREEN DIMMER
The CRC®-35R is equipped with a screen dimmer. If no key is pressed for 8 minutes, the
back lighting will go off. Pressing any key will turn the screen back on.

SCREEN PRINTING
To print any screen being displayed, press 2nd and then P.

March, 95 3-3 GENERAL OPERATING INSTRUCTIONS



CAPINTEC, INC. CRC®-35R

GETTING STARTED Chapter 4

POWER-UP SEQUENCE

When the CRC®-35R is turned on, the sign-on message will be displayed. Press any key to
continue. The main measurement screen is now displayed using the default nuclide and
default chamber if there is more than one chamber. The sign-on message is only displayed
when the system is first turned on.

PRELIMINARY PROCEDURES

The following should be done after the Calibrator is setup and prior to the first measurement:

1. Run DIAGNOSTICS (UTIL, DIAGNOSTICS).
The printout has your System Configuration and the defaults for Parameter / User
Preferences.

2. If the System Configuration is incorrect, change it via
UTIL, SETUP MENU, CONFIGURATION, MENU, SYSTEM CONFIGURATION.

3. Check the defaults for Parameter / User Preferences. If you want to use different
values, enter them via UTIL, SETUP MENU, PARAMETERS / USER
PREFERENCES.

4. Input Reference Source data.
Input calibration data for your reference sources via
UTIL, SETUP MENU, REFERENCE SOURCES, REFERENCE SOURCE DATA.
If your reference source is not Co57 or Co60 or Cs137 or Ba133, you must first
enter it using
UTIL, SETUP MENU, REFERENCE SOURCES, ADDITIONAL REFERENCE
NUCLIDES.

5. Choose the type of Linearity Test performed at your facility via
UTIL, SETUP MENU, DEFINE TESTS, LINEARITY TEST.
If Lineator or Calicheck is chosen, the calibration must be performed.

6. Choose the nuclides that you will use in your daily Constancy Test via

UTIL, SETUP MENU, DEFINE TESTS, CONSTANCY TEST.

Up to 10 nuclides may be chosen. Deviation can only be given for the chosen

nuclides. Note: this step is only necessary if deviation is desired.

May, 94 4-1 GETTING STARTED

CAPINTEC, INC. CRC®-35R

7. Perform Daily Test for each chamber in your system.
This includes: Background measurement, System Test, Accuracy Test, Constancy
Test.

8. Perform baseline Linearity Test.

9. Perform baseline Geometry Test.

May, 94 4-2 GETTING STARTED

CAPINTEC, INC. CRC®-35R

May, 94 4-3 GETTING STARTED



CAPINTEC, INC. CRC®-35R

Chapter 5

DEFINITION OF KEYS

Fig 5-1 shows the layout of the CRC®-35R keyboard.

F1 F2 F3 F4 TIME TEST BKG HOME

Mo99 Co57 Ga67 _ PREV SCREEN Ci/Bq CHAMBER 2nd
In111
ASSAY Tc99m ABC DEF UTIL
U4 12 3
U1 U5 BSP
I123 X GHI JKL MNO =
U2 Xe133 456
I131 ENTER
U3 PRS TUV WXY
_ 7 8 9

NUCL YES SPACE NO

Tl201 + [Fig. 5-1] QZ
CAL# 0

SOFT KEYS: F1, F2, F3, F4

The meaning of these keys changes with each screen.
Every screen that uses them shows a diagram of the keys with their meaning at the bottom
of the screen.

NUCLIDE KEYS: Co57, Ga67, Tc99m, In111, I 123, I 131, Xe133, Tl201

Pressing one of these keys selects that nuclide.

USER KEYS: U1, U2, U3, U4 , U5

Any one nuclide in memory may be assigned to a User Key.
When a key is assigned, it acts just like a Nuclide Key.

May, 94 5-1 DEFINITION OF KEYS

CAPINTEC, INC. CRC®-35R

NUCL Key:

Pressing this key allows the user to select any nuclide in memory (including nuclides added
by the user).
The nuclide is chosen using the number/ letter keys.

CAL # Key:

This key is only active on the Measurement Screen.
Pressing this key allows the user to input a calibration number to be used for the current
measurement.

TIME Key:

This key is only active on the Measurement Screen.
After pressing this key, a time is input. The activity at the input time of the source being
measured is displayed under the current activity along with the input time.
If the activity at an entered time is being displayed, pressing this key removes the display.

TEST Key:

This key is only active on the Measurement Screen.
Pressing this key brings up the TEST MENU.

BKG Key:

This key is only active on the Measurement Screen.
Pressing this key steps the user through the Background Measurement.

UTIL Key:

This key is only active on the Measurement Screen.
Pressing this key brings up the UTILITY MENU.

Mo99 Assay Key:

This key is only active on the Measurement Screen.
Pressing this key steps the user through a Moly Assay procedure.

HOME Key:

Press this key to return to the Measurement Screen.
Pressing it during the Measurement Screen causes any Test or Background being run at a
Remote, or by a computer, to be aborted.

May, 94 5-2 DEFINITION OF KEYS

CAPINTEC, INC. CRC®-35R

NUMBER / LETTER Keys:

The keys with Numbers and Letters on them are used to enter data. The decimal point is the
UTIL key.

BSP Key:

This is the backspace key and is used to erase the last character when entering data.

ENTER Key:

This is used to accept entered data.

ARROW Keys:

The arrow keys are used for several different functions:
When a question is asked, the Up Arrow is YES, and the Down Arrow in NO.

When a Menu is displayed, the Arrow keys are used to scroll through the menu.

When alpha numeric input is being entered, the Arrow keys are used to scroll through the
possible values on each number/ letter key.

2nd Key:

Second functions are obtained by pressing 2nd and 1,2 or 3.

PREV SCREEN Key:

Press 2nd and then 1.
This key returns the user to the Previous Screen.

Ci / Bq Key:

Press 2nd and then 2.
This key is only active on the Measurement Screen.
Pressing this key toggles the measurement between Curies and Becquerels.
It is only active if USER SELECTABLE has been chosen for Ci/Bq.

CHAMBER Key:

Press 2nd and then 3.
This key is only active on the Measurement Screen.
Pressing this key allows the user to change the chamber which is being controlled and
viewed by the Main Unit.
This key is not active if there is only 1 chamber in the system.

May, 94 5-3 DEFINITION OF KEYS



CAPINTEC, INC. CRC®-35R

MEASUREMENTS Chapter 6

MEASUREMENT SCREEN

The Measurement Screen is displayed after the Sign-on message. It is the main branching
point.
When HOME is pressed on any screen, you will be returned to the Measurement Screen.

Fig. 6-1 shows the Measurement Screen and indicates its features.

DISP INV TABLE PRINT

[Fig 6-1]

The screen displays: Name of the currently selected nuclide.
Nuclide Name:

Activity: Activity of the source in the chamber selected.

Date and Time: Current date and time.

Chamber Selected: Chamber selected by the user. It is only displayed on
systems that have more than 1 chamber.

May, 94 6-1 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

F1 = DISP: Press F1 key to Dispense the dose to a patient.
F2 = INV: Press F2 key to access the inventory functions.
F3 = TABLE: Press F3 key to print a Dose Table.
F4 = PRINT: Press F4 key to print a record of the measurement.
Other Active Keys:
Mo99 Assay: Press Mo99 Assay Key to perform a Moly Assay
NUCLIDE Keys: Press one of the keys to select indicated nuclide.
USER Keys: Press U1 to U5 to select nuclide assigned to that key.
NUCL: Press the NUCL Key to specify a nuclide.
CAL #: Press the CAL# Key to enter a calibration number.
TIME: Press the TIME Key to enter a different time for activity
display.
TEST: If the activity at a different time is being displayed, pressing
BKG: the TIME Key removes this display.
UTIL: Press the TEST Key to access Test Menu.
Ci / Bq: Press the BKG Key to measure Background Activity.
Press the UTIL Key to access Utilities Menu.
CHAMBER: Press the 2nd Key and the Ci/Bq Key to switch
measurement between Ci and Bq.
Press the CHAMBER Key to select another chamber.

MAKING A MEASUREMENT

To measure the activity of a source:
Insert source into the chamber
Select Nuclide

To print a record of the measurement:
Press PRINT (F4)

To find out what the activity will be at a different time:
Press TIME

May, 94 6-2 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

To Dispense the entire dose to a patient and record the result:
Press DISP (F1)

To remove display of activity at a different time:
Press TIME

SELECTING A NUCLIDE

To select a nuclide:
• Press one of the 9 pre-set nuclide keys

Co57 Ga67 Tc99m In111 I123 I131 Xe133 Tl201

• Press one of the 5 user assigned nuclide keys
U1 U2 U3 U4 U5
NOTE: Before using one of these keys, a nuclide must be assigned to the
key.
See: UTILITIES, SETUP MENU, USER KEY ASSIGNMENTS

• Press NUCL
Specify Nuclide: is displayed.
Input the nuclide name via the number/letter keys (only numbers will appear).
Press ENTER when done.
The entire name does not have to be input.
If the nuclide is not uniquely specified, a list of possibilities will appear.
(If there are more than 10 possibilities, SPECIFY FURTHER will appear.)
Use the arrow keys until the desired nuclide is highlighted and press ENTER.
If NUCL was accidentally pressed, press ENTER or PREV SCREEN to return to
Fig 6-1.

• Press CAL# for a calibration number which does not correspond to a nuclide in
memory.
CAL #: is displayed.
Input the desired calibration number and press ENTER.
The Calibration number entered will appear in the upper left hand corner of the
Measurement Screen, where the nuclide name is usually displayed.

If CAL# was accidentally pressed, press ENTER or PREV SCREEN to return to
Fig 6-1.

NOTE
Since neither the name of the source nor its half-life are known, TIME, DISP
and INV are not active when an entered Calibration number is being used.
The F1 and F2 and F3 keys will therefore be blank.

May, 94 6-3 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

SELECTING THE CHAMBER

If the system has more than 1 chamber, the chamber being viewed appears when
measurements are being made. To change the chamber being viewed:

Press 2nd and then press CHAMBER
Enter the new chamber number and press ENTER.

SELECTING Ci or Bq

Measurements can be displayed in Ci or Bq unless Ci ONLY or Bq ONLY has been chosen
in UTIL, SETUP MENU, Ci / Bq.
To change from Ci to Bq or from Bq to Ci:

Press 2nd and then press Ci/Bq

ENTERING TIME

The activity at another time can be displayed by pressing the TIME key to display Fig 6-2:

OK

[Fig 6-2]

Enter the desired time in 24 hour format (e.g. 1:00 am = 0100; 1:00 pm = 1300). The time
will be echoed with the current date as shown in Fig 6-3.

May, 94 6-4 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

DAY OK

[Fig 6-3]

The time can be specified for the current day or the next day.
Press DAY to toggle between Today and Tomorrow.
When the desired time and date are displayed, press OK.

The activity at the entered time will be displayed as shown in Fig 6-4.

DISP INV TABLE PRINT

[Fig 6-4]

The activity at the entered time will be displayed until TIME is pressed again.

May, 94 6-5 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

DISPENSING A DOSE

If the source being measured is to be dispensed to a patient, the data pertaining to this dose
may be printed and stored for printing in the Patient Report.
If the dose is to be given at a future time , press TIME and enter the time of the dose.
Pressing DISP (F1) from Fig 6-1 or Fig 6-4 brings up Fig 6-5 (Patient Screen):

UNIT OK

[Fig 6-5]

PAT. ID: This is the Patient's identification. It can consist of numbers and/or
letters. The maximum length is 12 characters.

TECH ID: This is the Technologist's identification. It can consist of numbers and/or
letters. The maximum length is 2 characters.

PAT. Rx: This is the dose to be given to the patient.

Press UNIT to toggle between mCi and µCi or MBq and BGq.
Press OK when entries are correct.

NOTE

All of these entries are optional.

May, 94 6-6 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

After OK is pressed, Fig 6-6 appears (assuming all entries have been made).

SAVE PRINT

[Fig 6-6]

Press PRINT to print a Ticket (or Single Line printout) and save data.
Press SAVE to save data or to return to Measurement Screen after printing.

The activity at the time of the dose will be compared with the Rx activity (if it was entered)
and a warning will be displayed if the deviation is greater than the allowed limit.
(See UTILITIES, SETUP MENU, PARAMETERS / USER PREFERENCES, ALLOWED
VARIATIONS)

May, 94 6-7 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

DOSE TABLE

When measuring a nuclide with a pre-set nuclide key (except Co57), it is possible to print the
volume required for a given dose at regular intervals in the future.

When measuring Tc99m, Ga67, In111, I 123, I 131, Xe133 or Tl201, press TABLE.
Fig. 6-7 will appear with the assayed activity displayed:

UNIT PRINT

[Fig. 6-7]

Enter the required dose and the volume of the sample.
Press UNIT to switch the unit of the dose from mCi to Ci to µCi or from MBq to GBq.

When the dose and volume are correct, insert a Pre-calibration ticket and press PRINT.

The required volume and concentration will be printed at intervals which depend on the
nuclide's half-life. The values are printed 30 times or until the required volume is greater
than the existing volume. Fig 6-8 is a sample ticket.

May, 94 6-8 MEASUREMENTS

CAPINTEC, INC. CRC®-35R

Tc99m

Mar 30 1994 13:42

Current Activity: 5.56mCi

Volume: 10.0ml

DOSE: 1.000 mCi CONC (mCi/ml)
TIME VOL(ml) 0.55
13:45 1.8 0.52
14:15 1.9 0.49
14:45 2.0 0.47
15:15 2.1 0.44
15:45 2.3 0.41
16:15 2.4 0.39
16:45 2.6 0.37
17:15 2.7 0.35
17:45 2.9 0.33
18:15 3.0 0.31
18:45 3.2 0.29
19:15 3.4 0.28
19:45 3.6 0.26
20:15 3.8 0.25
20:45 4.1 0.23
21:15 4.3 0.22
21:45 4.6 0.21
22:15 4.8 0.20
22:45 5.1 0.18
23:15 5.4 0.17
23:45 5.7 0.16
00:15 6.1 0.16
00:45 6.4 0.15
01:15 6.8 0.14
01:45 7.2 0.13
02:15 7.6 0.12
02:45 8.1 0.12
03:15 8.6 0.11
03:45 9.1 0.10
04:15 9.6

[Fig. 6-8]

May, 94 6-9 MEASUREMENTS



CAPINTEC, INC. CRC®-35R

Chapter 7

MOLY ASSAY

The CRC®-35R steps the user through a Moly Assay procedure.
The assay may be performed in the CAPMAC or the CANISTER.
If one of the procedures is to be performed all the time, choose the procedure in
UTIL, SETUP MENU, USER PARAMETERS / PREFERENCES, MOLY ASSAY.

To perform a Moly Assay, press Mo99 ASSAY key while in measurement screen.
If the assay method has not been uniquely specified, Fig 7-1 will appear:

[Fig 7-1]
Select the method to be used for the current test only.
If only CAPMAC or only CANISTER has been chosen in Utilities, this screen will be skipped.

May, 94 7- 1 MOLY ASSAY

CAPINTEC, INC. CRC®-35R

Mo99 BACKGROUND

Measuring the background for Mo99 is optional. This background will only be used for the
current assay. If it is skipped, the background previously measured by pressing BKG or
during the Daily Test will be used.

The following examples are for CAPMAC. CANISTER will be exactly the same except that
the screens will prompt for measurements in the CANISTER.

SKIP OK

[Fig 7-2]

Press SKIP if you don't want to measure background with the CAPMAC or CANISTER. You
will go directly to Mo99 assay (Fig 7-6).

Press OK to begin Mo99 background measurement.

Measuring Mo99 background is very similar to measuring background via BKG key or Daily
Test.

May, 94 [Fig 7-3] MOLY ASSAY

7- 2

CAPINTEC, INC. CRC®-35R

When a measurement is ready, Fig 7-4 appears:

1 26

[Fig 7-4]

The measurements are being averaged at this time.
Then you may accept the measurement and continue:

1 26

OK

[Fig 7-5]
NOTE
The displayed value for the Mo99 Assay will appear several times higher than the value
which is displayed by pressing the BKG key. This is because the displayed value has been
multiplied by the appropriate correction factor for use with the CAPMAC or the CANISTER.
Press OK to accept measurement and continue to Mo99 Assay, Fig 7-6.
NOTE
The activity will be tested to see if it's too high the same way that Background is tested.

May, 94 7- 3 MOLY ASSAY

CAPINTEC, INC. CRC®-35R

Mo99 ASSAY

You will now be instructed to measure the eluate in the CAPMAC or CANISTER.

OK

[Fig 7-6]
Press OK to begin the measurement.
Since this is also a measurement of a very low activity, the screens are similar to
background:

[Fig 7-7]

May, 94 7- 4 MOLY ASSAY

CAPINTEC, INC. CRC®-35R

When a measurement is ready, Fig 7-8 appears:

[Fig 7-8]
The measurements are being averaged at this time.
Then you may accept the measurement and continue:

OK

[Fig 7-9]

Press OK to accept measurement and continue to Tc99m assay.
NOTE

The activity will be tested to see if it's too high the same way that Mo99 Background is
tested.

May, 94 7- 5 MOLY ASSAY

CAPINTEC, INC. CRC®-35R

Tc99m ASSAY

The Tc99m Assay is performed next:

OK

[Fig 7-10]

Press OK to begin the Tc99m Assay.

OK

[Fig 7-11]
Press OK to accept the measurement.

NOTE
An error message will appear if the Tc99m activity is too low.

May, 94 7- 6 MOLY ASSAY

CAPINTEC, INC. CRC®-35R

The Mo99/Tc99m ratio is calculated and displayed.

The ratio is compared to the allowable value (which can be changed in
UTIL, SETUP MENU, USER PARAMETERS / PREFERENCES, ALLOWED VARIATIONS).

If the calculated time limit is less than 12 hours, a usage message is displayed depending
upon the usable time for the elution.

µ

OK

[Fig 7-12]

Press OK to acknowledges the usage message, erase it and continue.

µ

[Fig 7-13]
Enter the volume of the elution and press ENTER.

May, 94 7- 7 MOLY ASSAY

CAPINTEC, INC. CRC®-35R

The concentration of the elution is calculated and displayed.

µ

PRINT EXIT

[Fig 7-14]

Press PRINT to print a ticket with the details of the assay and remain on this screen.
Press EXIT to return to Measurement screen.

May, 94 7- 8 MOLY ASSAY

CAPINTEC, INC. CRC®-35R

Chapter 8

TESTS

The CRC®-35R can step the user through Daily Test, System Test, Accuracy Test,
Constancy Test, Quality Control, Linearity Test, Geoemtry Test
Each test , except Quality Control, is a test of a particular chamber and must be performed
for each chamber of a multi-chamber system.

Pressing TEST at the measurement screen brings up the Test Menu (Fig 8-1) :

[Fig 8-1]

Select DAILY to begin the Daily Test

The Daily Test consists of:
Background
System Test
Accuracy Test
Constancy Test

Background can also be measured by pressing BKG key at the measurement screen.

Daily test begins by measuring background for the selected chamber (Fig 8-2)

August, 94 8-1 TESTS

CAPINTEC, INC. CRC®-35R
BACKGROUND

BEGIN

[Fig 8-2]
A background measurement must be made with no sources in or near the chamber.
Press BEGIN to begin background measurement.

[Fig 8-3]

Since very low activity is being measured, there is a delay before an accurate measurement
is available.

August, 94 8-2 TESTS

CAPINTEC, INC. CRC®-35R

When a measurement is available, Fig 8-4 appears

[Fig 8-4]
When enough measurements have been made for a valid background, the Fig 8-5 appears:

SAVE

[Fig 8-5]
Press SAVE to save the background value. Continues Daily Test or returns to Measurement
Screen if Background was accessed via BKG key.

August, 94 8-3 TESTS

CAPINTEC, INC. CRC®-35R

If the background is high, but within acceptable limits, Fig 8-6 appears instead of
Fig 8-5:

SAVE

[Fig 8-6]
If you want to repeat the measurement, Press PREV SCREEN to restart Daily Test or HOME
to return to Measurement Screen.
If you think that the value is acceptable, press SAVE to save the background value.
If the background is too high, Fig 8-7 will appear instead of Fig 8-5 or Fig 8-6

EXIT

[Fig 8-7]
The measured background cannot be accepted.
Press EXIT to return to Test Menu (Fig 8-1) or to Measurement Screen if BKG key was
pressed

August, 94 8-4 TESTS

CAPINTEC, INC. CRC®-35R

SYSTEM TEST

SYSTEM TEST is the next part of Daily Test.
System Test can also be reached directly from the Test Menu

BEGIN

[Fig 8-8]
System Test must also be performed with no sources in or near the chamber.
Press BEGIN to begin System Test and bring up Fig 8-9

August, 94 [Fig 8-9] TESTS

8-5

CAPINTEC, INC. CRC®-35R

When the measurement is done and the system voltage is OK ,Fig 8-10 is displayed:

[Fig 8-10]
Press ENTER to accept System Test Result. Proceeds to the next part of Daily Test or
returns to Test Menu if reached directly from Test Menu.

If the measurement is out of range, Fig 8-11 will be shown instead of Fig 8-10:

[Fig 8-11]

Press ENTER to return to Test Menu.

August, 94 8-6 TESTS


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CRC ® -35R Remote Display Manual- Rev. A