Classification of Antiretroviral Drugs

Classification of Non-Nucleoside
Antiretroviral Drugs Reverse

Nucleoside Transcriptase
Reverse Inhibitors

Transcriptase Integrase
Inhibitors Inhibitors

Entrance/ Protease
Fusion Inhibitors

Inhibitors

Classification of Antiretroviral Drugs & Examples

Nucleoside Non-Nucleoside Integrase Protease Entrance/
Reverse Reverse Inhibitors Inhibitors Fusion

Transcriptase Transcriptase Dolutegravir Lopinavir Inhibitors
Inhibitors (NRTIs) Inhibitors (NNRTIs) Raltegravir Ritonavir
Indinavir Enfuvirtide
Zidovudine Efavirenz Atazanavir Maraviroc
Nevirapine Darunavir
[Thymidine analogue] Etravirine

Lamivudine

[Cytidine analogue]

Emtricitabine

[Cytidine analogue]

Abacavir

[Guanosine analogue]

Tenofovir
[Adenosine analogue]

Entrance of Retroviruses:
Blocked by

Entrance Inhibitors

cDNA integration:
Blocked by

Integrase Inhibitor

RNA replication:
Blocked by

NRTI & NNRTI

Cleavage of log-chain protein:
Blocked by

Protease Inhibitor