Molecules of life
&
Cell structures and Functions
Name : EUNICE LING LI XUAN
Matrix Number : MS2213201314
Practicum : H3T02A
Main types of molecules
Water :
• It is a universal solvent
due to its polarity.
• It has high specific heat
capacity
• It has high latent heat of
vaporisation
• It has maximum density
of 4°C
• It has cohesion force
between water
molecules
Carbohydrates :
• There are 3 classes of
carbohydrates which are
monosaccharides,
disaccharides and
polysaccharides.
• It is composed of carbon
(C), hydrogen (H) and
oxygen (O) with the
proportion 1:2:1
Main types of molecules
Lipids:
• It is made up or C,H,O
• It is a large and non-polar
• There are 3 types of lipids:
= Triglycerides, Phospholipids, Steroids
Protein :
• Protein = Polypeptides
= (Monomer = amino acid)
• It is made up of C,H,O,N (sometimes S)
• There are 4 levels of protein structure :
= Primary, Secondary, Tertiary & Quaternary
Nucleic Acid :
• There are two types of
nucleic acid :
1. Deoxyribonucleic acid
(DNA)
2. Ribonucleic acid (RNA)
• Monomer = nucleotide
Classify lipid into three main
types based on their structures
and characteristics
Structures :
A triglyceride or triacylglycerol is formed when 3
hydroxyls (OH-) groups of a single glycerol
molecule react with the carboxyl group (COOH-)
of 3 fatty acids by ester bond.
In the presence of acid and heat, or under
biological conditions, triglycerides (fats) can be
hydrolyzed to produce glycerol and three fatty
acids.
Characteristics :
Triglycerides are completely hydrophobic = they
cannot integrate into membranes. Thus,
triglycerides bind to lipoproteins to enable them
to travel through the blood.
Phospholipids is a compound lipid consist of two
hydrophobic “tails” which are fatty acid chains,
and one hydrophilic “head” which is phosphate
group.
Phospholipid form lipid bilayers and are a key
component of all the cell membranes.
Phospholipids are amphipathic molecules.
Phospholipids are water-soluble due to polar head.
Phospholipid is charged molecules.
Steroid is a molecular structure that contained
17 carbon atoms arranged in four fused
hydrocarbon rings.
Steroid hormones - Can easily diffuse across both
cell and nuclear membrane.
E.g : Testosterone, Progesterone, Aldosterone ++
Steroids vary by the functional groups attached to
this four-ring core and by the oxidation state of
the rings.
The structure of
plasma membrane.
According to the fluid mosaic model, protein molecules
float within the phospholipid bilayer, forming a mosaic
pattern that changes frequently.
Figure above is the labelled diagram of plasma membrane
• 1. The head of phospholipid molecule in outer
layer face the extracellular fluid
2. Phospholipid heads in the inner layer face the
cytoplasm.
3. The tails of the phospholipid molecule of two
layers face each other.
• There are few type of protein molecules embedded
partially or fully within the membrane :
1. The protein molecules with channels or canals are
known as channel protein .
2. The protein molecules that function as carrier are
known as carrier protein
*** Some protein & lipid have carbohydrate chain
attached to them which known as glycoprotein or
glycolipid.
There are also cholesterol molecules in the plasma
membrane which make the phospholipid bilayer stronger,
more flexible and less permeable to water-soluble
substances such as ions.
Channel Protein Carrier Protein
All in all, the phospholipid bilayer, protein &
cholesterol are not static but form a dynamic
and flexible structure which make plasma
membrane more flexible & have fluid
characteristics.
Explain how certain type of cells
consists type of lipids ensures the
fluidity of the plasma membrane
while some other type of lipids
may reduce its fluidity.
1. Cholesterol
o It can keep the membrane fluid as it lies alongside of
phospholipid in plasma membrane that tends to dampen
the effects of temperature on the membrane.
o It functions as a buffer, preventing lower temperatures
from inhibiting fluidity and preventing higher
temperatures from increasing fluidity too much.
2. Saturated fatty acid
o It has no double bonds in the hydrocarbon chain, and the
maximum amount of hydrogen.
o The absence of double bonds decreases fluidity, making
the membrane very strong and stacked tightly.
3. Unsaturated fatty acid
o It has at least one double bond, creating a "kink" in the
chain.
o The double bond increases fluidity.