DRUG ALBUM PKDHS 2021

NEOMYCIN 0.5% CREAM

CATEGORY DESCRIPTION
PREGNANCY D
LACTATION
SPECIAL COUNSELING No human data- Probably compatible

POINT Prolonged use may result in overgrowth of non-
susceptible organisms

187

NEVIRAPINE 200 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B
SPECIAL COUNSELING
Compatible
POINT
• Skin rash, nausea, vomiting, headache, fatigue,
diarrhoea, abdominal pain

• Advise patient to practice safe sex as drug dose
not prevent disease transmission

• Instruct patient to contact HCP for instructions if
dose is missed for more than 7 consecutive days

188

NICOTINE 10 MG/ 16 HOUR
TRANSDERMAL PATCH

CATEGORY DESCRIPTION
PREGNANCY
LACTATION D

SPECIAL COUNSELING Nicorette passes freely into breast milk in quantities
POINT that may affect the infant, even at therapeutic doses.
The use of Nicorette Invisi Transdermal Patch should

therefore be avoided when breastfeeding.

Nicorette Invisi Transdermal Patch should be applied
to clean, dry intact areas of hairless skin for example
on the hip, upper arm, or chest. These areas should
be varied each day and the same site should not be

used on consecutive days.

189

NICOTINE 15 MG/ 16 HOUR
TRANSDERMAL PATCH

CATEGORY DESCRIPTION
PREGNANCY
LACTATION D

SPECIAL COUNSELING Nicorette passes freely into breast milk in quantities
POINT that may affect the infant, even at therapeutic doses.
The use of Nicorette Invisi Transdermal Patch should

therefore be avoided when breastfeeding.

Nicorette Invisi Transdermal Patch should be applied
to clean, dry intact areas of hairless skin for example
on the hip, upper arm, or chest. These areas should
be varied each day and the same site should not be

used on consecutive days.

190

NICOTINE 2 MG GUM

CATEGORY DESCRIPTION
PREGNANCY D
LACTATION
Women should take the product just after having
SPECIAL COUNSELING breastfeeding. Nicotine passes freely into breast
POINT milk in quantities that may affect the child even with
therapeutic doses. Nicorette chewing gum should

therefore be avoided during breast-feeding.

Acidic beverages (e.g. coffee, juices, carbonated soft
drinks) may inhibit buccal absorption of nicotine

191

NICOTINE 4 MG GUM

CATEGORY DESCRIPTION
PREGNANCY D
LACTATION
Women should take the product just after having
SPECIAL COUNSELING breastfeeding. Nicotine passes freely into breast
POINT milk in quantities that may affect the child even with
therapeutic doses. Nicorette chewing gum should

therefore be avoided during breast-feeding.

Acidic beverages (e.g. coffee, juices, carbonated soft
drinks) may inhibit buccal absorption of nicotine

192

NIFEDIPINE 10 MG TABLET

CATEGORY DESCRIPTION

PREGNANCY C

LACTATION Limited Human Data—Probably Compatible

SPECIAL • Discontinue if ischaemic pain follows after admin
COUNSELING POINT • Avoid activities requiring mental alertness or
coordination until drug effect are realized as drug may
cause dizziness

• May cause heartburn, nausea, or headache

193

NORETHISTERONE 0.35 MG TABLET

CATEGORY DESCRIPTION

PREGNANCY X

LACTATION Compatible

SPECIAL COUNSELING Side effects include irregular menstrual bleeding,
POINT breast cancer, visual abnormalities (e.g. partial or

complete loss of vision, proptosis, diplopia),
migraine, depression, decreased glucose tolerance

194

NYSTATIN 100,000 UNITS/ML
SUSPENSION

CATEGORY DESCRIPTION

PREGNANCY C

LACTATION Compatible

SPECIAL COUNSELING POINT • May cause hypersensitivity reactions, irritation.
• May cause nausea and vomiting in patients
taking larger doses of oral nystatin

195

ORAL REHYDRATION SALT

CATEGORY DESCRIPTION
PREGNANCY
Unassigned. Use in patients with pre-eclampsia is
LACTATION contraindicated. The product should only be
SPECIAL COUNSELING
administered if the expected benefit to the mother
POINT is thought to outweigh any possible risk to the
foetus or neonate

Compatible

• Do not use oral rehydration salts to treat
diarrhoea for more than 2–3 days, unless
consulted.

• Only use water to mix with the oral rehydration
salts; do not use milk or juice and never add
extra sugar or salt.

196

OSELTAMIVIR 75MG CAPSULE

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C
SPECIAL COUNSELING
Compatible
POINT
May be taken with or without food. May be taken with
meals to reduce GI discomfort. Capsule may be

opened & mixed with sweetened food products eg
chocolate syrup, sweetened condensed milk, apple

sauce or yogurt.

197

OXYTOCIN 10UNITS/ML INJECTION

CATEGORY DESCRIPTION
PREGNANCY X
LACTATION
SPECIAL COUNSELING POINT No data available
- Only use to induce labor. Not for long

term period.

198

OXYTOCIN 5 UNITS & ERGOMETRINE
MALEATE 0.5MG/ML INJECTION

CATEGORY DESCRIPTION
PREGNANCY X
LACTATION
SPECIAL COUNSELING POINT No data available
- Only use to induce labor. Not for long

term period.

199

PANTOPRAZOLE 40MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B

SPECIAL COUNSELING POINT Not recommended- present in breast
milk

-Should be taken before meals and
swallow as whole (not to crush the

tablet).
- Advise patient that drug may increase
risk for osteoporosis-related fractures
with multiple daily doses and continued

longer than a year.

200

PARACETAMOL 125MG SUPPOSITORY

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B

SPECIAL COUNSELING POINT Present in breast milk- but minimal
effect on infants

- Advise patient not to take other
paracetamol preparation with least
6 hours gap.

- Not to take more than 4g per day

201

PARACETAMOL 250MG SUPPOSITORY

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B

SPECIAL COUNSELING POINT Present in breast milk- but minimal
effect on infants

- Advise patient not to take other
paracetamol preparation with least
6 hours gap.

- Not to take more than 4g per day

202

PARACETAMOL 250MG/ML SYRUP

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B

SPECIAL COUNSELING POINT Present in breast milk- but minimal
effect on infants

- Advise patient not to take other
paracetamol preparation with least
6 hours gap.

- Not to take more than 4g per day

203

PARACETAMOL 500 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B

SPECIAL COUNSELING POINT Present in breast milk- but minimal
effect on infants

- Advise patient not to take other
paracetamol preparation with least
6 hours gap.

- Not to take more than 4g per day

204

PERINDORIL 4 MG AND INDAPAMIDE
1.25MG TABLET

CATEGORY DESCRIPTION
PREGNANCY D
LACTATION
SPECIAL COUNSELING POINT Contraindicated

-Patient should avoid activities
requiring mental alertness or
coordination as drug may cause
dizziness and symptomatic

hypotension.
-Advise patient to immediately report

signs/symptoms of angioedema,
laryngeal edema, or severe dry cough.

205

PERINDOPRIL 4 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY D
LACTATION
SPECIAL COUNSELING POINT Contraindicated

-Patient should avoid activities
requiring mental alertness or
coordination as drug may cause
dizziness and symptomatic

hypotension.
-Advise patient to immediately report

signs/symptoms of angioedema,
laryngeal edema, or severe dry cough.

206

PERINDORIL 8 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY D
LACTATION
SPECIAL COUNSELING POINT Contraindicated

-Patient should avoid activities
requiring mental alertness or
coordination as drug may cause
dizziness and symptomatic

hypotension.
-Advise patient to immediately report

signs/symptoms of angioedema,
laryngeal edema, or severe dry cough.

207

PERMETHRIN 5% W/V LOTION

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B

SPECIAL COUNSELING POINT Breastfeeding is not expected to result in
significant exposure to a breastfed child.

- Drugs may exacerbate pruritus,
erythema and stinging/ burning of skin.
- Scabies: Apply over whole body (from

neck to soles). Wash off after 8-12
hours and repeat after 1 week.

208

PETHIDINE HCl 50MG/ML INJECTION

CATEGORY DESCRIPTION
PREGNANCY B- not recommended in long term
LACTATION Not recommended in long period
SPECIAL COUNSELING POINT - Avoid use in renal impairment patient.

209

PHENOBARBITONE 30 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION D
SPECIAL COUNSELING POINT
Present in breast milk- risk over benefit

- Patient should avoid activities requiring
mental alertness/ coordination until
drug effects are realized.

- May cause dizziness, light-headedness,
somnolence, insomnia, anxiety and
irritability.

- Not to increase dose unless instructed
by healthcare professionals.

210

PHENOXYMETHYL PENICILLIN 125MG
TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B
SPECIAL COUNSELING POINT
Present in breast milk- risk over benefit

- This drug may decrease
effectiveness of oral contraceptives

with concurrent use.
- Advise patient to report sign/

symptoms of hemolytic anemia,
leukopenia or thrombocytopenia.
- Need to complete treatment
duration to avoid drug resistance.

211

PHENYTOIN SODIUM 100MG CAPSULE

CATEGORY DESCRIPTION
PREGNANCY
LACTATION D

SPECIAL COUNSELING POINT Compatible- not to be used unless
maternal benefit outweigh risk to fetus.
- Advise patient to report symptoms of
purple glove syndrome, hepatotoxicity,

lymphadenopathy and serious skin
reaction.

212

PIZOTIFEN 0.5MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C

SPECIAL COUNSELING POINT Present in breast milk- Not
recommended

-Drug can cause drowsiness, dizziness,
dry mouth, constipation and increase in
appetite. Avoid driving and operation of

machinery.

213

PNEUMOCOCCAL POLYSACCHARIDE AND
NON-TYPEABLE HAEMOPHILUS INFLUENZAE
(NTHI) PROTEIN D CONJUGATE VACCINE (10-

VALENT, ADSORBED)

CATEGORY DESCRIPTION
PREGNANCY No data available
LACTATION No data available
SPECIAL COUNSELING POINT - Usually given to pediatrics.
- Monitor Adverse Effects Following
Immunization (AEFI) after
administering vaccines.

214

POTASSIUM CHLORIDE 1G/10ML
INJECTION

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C
SPECIAL COUNSELING POINT
Compatible

- Advise patient to report sign/
symptoms of gastrointestinal ulcer
or arrhythmias.

215

POTASSIUM CHLORIDE 600MG SR
TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C
SPECIAL COUNSELING POINT
Compatible

- Advise patient to report sign/
symptoms of gastrointestinal ulcer
or arrhythmias.

- Advise patient to take with meals
and a full glass of water or other
liquid to avoid gastric irritation

216

POTASSIUM PERMANGANATE 1:10,000
SOLUTION

CATEGORY DESCRIPTION
PREGNANCY
LACTATION No data available
SPECIAL COUNSELING POINT
Use with caution

- Use as wash (final rinse) dab/ wet
wrap for 20 minutes until there is no
weeping lesions.

- Use immediately after diluting.
Solution that turn brown (oxidized) is

not effective.
- Advise patient to stop using once

skin become dry to avoid fissuring of
skin.

217

POVIDONE IODINE 10% (EQUIVALENT
TO 1% IODINE) SOLUTION

CATEGORY DESCRIPTION
PREGNANCY D- when use as topical/ vaginal
LACTATION
SPECIAL COUNSELING POINT Compatible
- Usually use as topical antiseptic during

procedure or surgery.

218

PRAVASTATIN SODIUM 20MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION X
SPECIAL COUNSELING POINT
Contraindicated

- Recommend female patients of
reproductive potential to avoid
pregnancy during treatment.

- Advise patient to immediately
report symptoms of myopathy,
rhabdomyolysis and liver injury.

219

PRAZOSIN HCl 1 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C
SPECIAL COUNSELING POINT
Present in breast milk- use with caution.

- This drug may cause dizziness and
drowsiness, if affected, do not drive
or operate machinery.
- Drug also can cause postural
hypotension, advise patient not to
change standing/ sitting position
abruptly.

220

PRAZOSIN HCl 2 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C
SPECIAL COUNSELING POINT
Present in breast milk- use with caution

- This drug may cause dizziness and
drowsiness, if affected, do not drive
or operate machinery.
- Drug also can cause postural
hypotension, advise patient not to
change standing/ sitting position
abruptly.

221

PRAZOSIN HCl 5 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY C
LACTATION
SPECIAL COUNSELING POINT Present in breast milk- use with caution
- This drug may cause dizziness and

drowsiness, if affected, do not drive
or operate machinery.

- Drug also can cause postural
hypotension, advise patient not to
change standing/ sitting position
abruptly.

222

PRE/POST NATAL VITAMIN & MINERAL
CAPSULE

CATEGORY DESCRIPTION
PREGNANCY A
LACTATION
SPECIAL COUNSELING POINT Compatible
- Advise patient for missed dose
management, not to double the dose.

Double dose may lead to
hypervitaminosis.

223

PRE/POST NATAL VITAMIN & MINERAL
TABLET

CATEGORY DESCRIPTION
PREGNANCY A
LACTATION
SPECIAL COUNSELING POINT Compatible
- Advise patient for missed dose
management, not to double the dose.

Double dose may lead to
hypervitaminosis.

224

PREDNISOLONE 5 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
B – not recommended in first trimester.
LACTATION (Human data suggest risk)
SPECIAL COUNSELING POINT Compatible

- Not recommended to use in longer
period unless indication.

- Drug may cause hypertension, fluid
retention, weight gain, insomnia
and decrease growth in pediatrics.

225

PROCHLORPERAZINE MALEATE 5MG
TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B – not recommended in 3rd trimester
SPECIAL COUNSELING POINT
No data available- potential toxicity.

- May cause extrapyramidal
syndrome (EPS) in patient.

- Advise patient not to take
concomitantly with calcium and
magnesium based antacid.

226

PROCHLORPERAZINE MESYLATE
12.5MG/ML INJECTION

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B – not recommended in 3rd trimester
SPECIAL COUNSELING POINT
No data available- potential toxicity.

May cause extrapyramidal syndrome
(EPS) in patient.

- Advise patient to maintain adequate
hydration to prevent volume depletion

and hypotensive effects.

227

PROLASE TABLET

CATEGORY DESCRIPTION
PREGNANCY No data available
LACTATION No data available
SPECIAL COUNSELING POINT - Advise patient to chew the tablet.

228

PROMETHAZINE HCl 25MG/ML

CATEGORY DESCRIPTION
PREGNANCY C
LACTATION
SPECIAL COUNSELING POINT No data available- potential toxicity
-Advise patient to report EPS and
neuroleptic malignant syndrome (fever,
sweating, stupor, unstable blood

pressure and muscle rigidity)

229

PROPRANOLOL HCl 40 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C- suggest risk in 2nd and 3rd trimester
SPECIAL COUNSELING POINT
Present in breast milk- use with caution

- Counsel patient to report sign of
bronchospasm or exacerbation of
lower respiratory tract infection.

- Advise diabetic patient to carefully
monitor blood glucose as drug may
mask symptoms of hypoglycemia.

230

PROPYLTHIOURACIL 50 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION D
SPECIAL COUNSELING POINT
Compatible

- Advise patient to report sign/
symptoms of hepatic dysfunction such

as aneroxia, pruritus, right upper
quadrant pain, fatigue and yellowing of

eyes.

231

PYRAZINAMIDE 500 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C

SPECIAL COUNSELING POINT Limited human data- probably
compatible

- Advise patient to report sign/
symptoms of hepatotoxicity or gout.

232

PYRIDOXINE HCl 10 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY A
LACTATION
SPECIAL COUNSELING POINT Compatible
- Drug may cause paresthesia and

somnolance.

233

RANITIDINE 25 MG/ML INJECTION

CATEGORY DESCRIPTION
PREGNANCY
LACTATION B

SPECIAL COUNSELING POINT Limited human data- probably
compatible

- Patient with CrCl < 50ml/min should
be administer 50mg every 18 to 24
hours and adjust dose cautiously if
needed.

234

RIFAMPICIN 150 MG CAPSULE

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C
SPECIAL COUNSELING POINT
Compatible

- Advise patient to report symptoms
of hepatotoxicity and cutaneous
adverse reaction.

- Counsel that drug may cause
discolouration of teeth, urine,
sweat, sputum and tears.

235

RIFAMPICIN 150 MG, ISONIAZID 75
MG, PYRAZINAMIDE 400 MG &

ETHAMBUTOL HCl 275 MG TABLET

CATEGORY DESCRIPTION
PREGNANCY
LACTATION C
SPECIAL COUNSELING POINT
Compatible

- Advise patient to report symptoms
of hepatotoxicity, cutaneous
adverse reaction, numbness,

changes of vision and arthralgia.
- Ask patient to take pyridoxine in

the regimen to avoid vitamin B6
deficiency.

236