Cancer: From Genomics to Pharmaceutics
Cancer is a devastating disease that affects millions of people worldwide, causing significant morbidity and mortality. With the development of new technologies and the abundance of genomic data available, researchers can better understand the genetic causes of cancer and develop targeted therapies. Recent research on cancer genome data has altered our understanding of the hallmarks of cancer due to the discovery of novel malignant transformation mechanisms. The integration and analysis of big genomic data have provided new insights into the evolution of cancer, metastasis mechanisms, and germline predisposition to cancer. Results of international genome projects opened a new window to transcribed genomic regions and the noncoding RNA world. Additionally genome editing approaches are now in use in clinics and giving scientists the ability to change the genetic material not only for Mendelian type of genetic disorders as well as cancer. This book, entitled Cancer: From Genomics to Pharmaceutics, is a part of the ‘100 e-books project on the 100th Anniversary of the Republic of Turkey’ designed by ˙Istanbul University. The aim of the book is to provide a comprehensive overview of the latest developments in cancer research, focusing on the intersection of genomics and pharmaceuticals as well as to increase the academic co-operation between PhD candidates and supervisors that all chapters are co-written by PhD candidates and their supervisors. This book is intended for researchers, clinicians, students, and anyone interested in the latest developments in cancer research. It is designed to provide a comprehensive overview and to serve as a valuable resource for those working in the field. We hope that this book will contribute to the recent knowledge and attention of cancer research.
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