PGT-A Brochure - Genomic Prediction

IVF GUIDE


Preimplantation Genetic Testing
for Aneuploidies (PGT-A) is a genetic test performed on the embryo biopsies to determine if the correct number of chromosomes is in the embryo.
..PGT-A


WHAT IS THE BENEFIT OF DOING PGT-A?
Screening embryos for extra or missing genetic material may help you and your doctor decide which embryos should be prioritized for transfer because most embryos with a chromosome abnormality will not result in a pregnancy. Determining which embryos have normal chromosomes also .


WHAT IS THE BENEFIT OF DOING PGT-A?
• Decreases the chance of miscarriage
• Increases the chance that a healthy baby is born
• Decreases the number of IVF cycles needed,
saving time and money
• Increases likelihood of a single embryo transfer (SET),
which decreases the chance of a multiple pregnancy


Is PGT-A accurate?
Yes, diagnostic accuracy is greater than 98%.
What other kinds of PGT studies are offered through
Genomic Prediction Clinical Laboratory (GPCL)?
We are the only laboratory that currently offers PGT for polygenic disorders, LifeViewTM — which tests for conditions influenced by genetic variants
in more than one gene. For individuals with a history of a chromosome rearrangement, PGT-SR (structural rearrangement screening, also known as chromosomal PGD), is available. PGT-M studies are available for individuals with a personal or family history of monogenic (single-gene) disorders.
I have questions about this testing. Who can I talk to?
GPCL provides free pre-test genetic counseling about PGT-A. To schedule an appointment, please have your clinic make a referral and we will contact you shortly thereafter
to schedule your genetic counseling appointment.


The odds of having an
aneuploid embryo increase with maternal age.
Age Risk Age
30 23.2% 38
31 31% 39
32 31.1% 40
33 31% 41
34 31.3% 42
35 34.5% 43
36 35.5% 44
37 42.6% 45
PMID: 24355045
Genomic Prediction Clinical Laboratory
Risk
47.9% 52.9% 58.2% 68.9% 75.1% 83.4% 88.2% 84.3%
GPCL’s advances in genetic testing provide couples undergoing IVF a cost-effective means to “look into the future” of their unborn child’s health. We can accurately predict his or her risk for many genetic conditions — due to chromosomal abnormality; monogenic disorders; and polygenic diseases such as
Type 1 and Type 2 Diabetes, Breast Cancer and Coronary Artery Disease.
gpclaboratory.com