Lifeview (PGT-P)

IVF GUIDE


is a genetic test performed on embryo biopsies which screens for polygenic disorders, such as Type 1 and Type 2 Diabetes, Breast Cancer and Coronary Artery Disease. These are very common conditions, found within many families.
For a complete list of the disorders tested, please go to our website: gpclaboratory.com


HOW DOES THE TESTING WORK?
Genomic Prediction Clinical Laboratory (GPCL)
looks at the genetic material in each embryo to determine if the risk for each of these conditions is higher than the average risk in the general population. You have the option to screen for one, some or all of the conditions on the panel.


Type 1 Diabetes Types 2 Diabetes Coronary Artery Disease Heart Attack Hypercholesterolemia Hypertension Testicular Cancer Prostate Cancer Malignant Melanoma Basal Cell Carcinoma Intellectual Disability Idiopathic Short Stature
Risk
0.4% High
32% Normal 9.8% Normal 15.7% Normal 0.1% Normal 53% Normal 1.1.% Normal 8.4% Normal 1.9% Normal 27% Normal - Normal - Normal
Avg Ratio Risk
Risk Percentile
0.1% 4.0x 98% 35% 0.9x 42% 33% 03x 2% 15% 1.0x 52% 0.3% 0.3x 3% 50% 1.1x 58% 0.5% 2.2x 85% 11% 0.8x 36% 2.6% 0.7x 39% 30% 0.9x 42% 2.1% - - 2.1% - -


What is a polygenic disorder?
A polygenic disorder is a condition caused by many genes. We all have about 20,000 genes in every cell in our body. You inherit your genes from your parents.
Is LifeViewTM (PGT-P) a diagnostic test? No,LifeViewTM (PGT-P)isascreeningtest.Diseaseriskisnot eliminated in embryos with a “normal” risk for a condition.
What is the benefit of performing LifeViewTM (PGT-P)? Identifying embryos that are at high risk may help you and your doctor decide which embryos should be prioritized for transfer.
Can I do PGT-A testing if I want to do LifeViewTM (PGT-P)? Yes, PGT-A (aneuploidy screening, also known as PGS) is included with LifeViewTM (PGT-P) at no additional charge.
Questions continued on next page


What other kinds of PGT studies
are offered through GPCL?
PGT-M studies are available for individuals with a personal or family history of monogenic (single-gene) disorders. For individuals with a history of a chromosome rearrangement, PGT-SR (structural rearrangement screening, also known as chromosomal PGD) is available.
I have questions about this testing.
Who can I talk to?
GPCL provides free pre-test genetic counseling about LifeViewTM (PGT-P).
To schedule an appointment, please have your clinic make a referral to GPCL. We will contact you shortly thereafter to schedule your genetic counseling appointment.
Genomic Prediction Clinical Laboratory
GPCL’s advances in genetic testing provide couples undergoing IVF a cost-effective means to “look into the future” of their unborn child’s health. We can accurately predict his or her risk for many genetic conditions — due to chromosomal abnormality; monogenic disorders; and polygenic diseases such as
Type 1 and Type 2 Diabetes, Breast Cancer and Coronary Artery Disease.
Currently not applicable to all ancestries. Please inquire for more information.
gpclaboratory.com Contact us at 844-GPCLABS (844-472-5227)