Wine Dr

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®



WINE WAS ALWAYS GOOD FOR YOU.
NOW IT MAY BE EVEN BETTER.

"Whether wine is a nourishing drink,
a medicine or a poison is a matter
of dosage."

– Paracelsus, 1493-1541, alchemist, astrologer, physician;
Father of modern pharmacology and toxicology



Background

It is believed that the first ever grape wine was wine has powerful anti-inflammatory properties
produced and consumed in Northern China which is important to protect the body’s tissues from
approximately 9,500 years ago. Whether as a degenerative damage including infarction and tissue
medicine or as a mixing medium for other medicines, death. In fact, regular wine consumption has the
Chinese doctors have used wine for its medicinal potential to reduce death rates from vascular
benefits for over 5,000 years. disease - such as heart disease and stroke, which are
Modern day medical science has now allowed for a amongst the world's leading killers - by up to 50%!
more comprehensive understanding of wine’s health It turns out that grapes, especially red grapes,
benefits. Wine has been shown to increase the levels amongst all fruit and food contains the highest
of “good cholesterol” and decrease the levels of concentrations of resveratrol. This unique aspect
“bad cholesterol” in the blood; its been shown to act of grape wine, and the extraordinary properties of
as an anticoagulant, preventing potential blockage of resveratrol, has been the interest of extensive
the arteries; contain potent antioxidant activity that scientific research over the past several years.
protects the blood vessels from atherosclerosis; and

Resveratrol & its Benefits

The human body uses many complex biochemical quercetin and most importantly the polyphenol
pathways and reactions to function; but these Resveratrol.
reactions result in waste products such as free These are amongst nature's most potent antioxidants
radicals (molecular compounds that contain an and can reduce oxidation by up to 100%.
extra unpaired electron). These antioxidants occur mainly in the grape skin
These free radicals are unstable and cause biological to protect it from disease, such as fungal infections,
havoc (oxidative damage), which contributes during a very moist vintage.
significantly to degenerative diseases such as cancer, The fermentation process of wine produces alcohol
dementia, diabetes, vascular disease (including heart and liberates these antioxidants from the grape skin,
attack and stroke), macular degeneration (the most making them available to protect our cells and body
common cause of blindness in people over 65) when consumed.
and arthritis. Resveratrol is the only naturally occurring substance
This is why there is now great interest in that activates the Sirtuins, cellular proteins that
antioxidants of various types, because antioxidants enable cells to live longer by modulating cellular
slow down this deterioration caused by oxidation. energetics. The Sirtuins have been implicated in
The standard benchmark antioxidants that people influencing cellular processes such as ageing,
consume are Vitamin C, Vitamin E, garlic and ginseng, inflammation, stress resistance, energy efficiency
which reduce oxidation by up to 20%. and alertness during low calorie situations.
The main antioxidants in wine are epicatechin, They can even control circadian rhythms
(sleep clocks).

Resveratrol may offer the following benefits: 11. Reduces Parkinson’s disease and
essential tremor
1. Reduces heart attacks and ischemic
strokes by up to 50% 12. Reduces macular degeneration by up to 34%
13. Increases bone density, reducing
2. Reduces bad cholesterol
3. Reduces dementia by up to 80% osteoporosis risk
4. Reduces insulin resistant diabetes by up 14. Assists with weight loss and management
15. May assist in the treatment of bronchial asthma
to 50% 16. Reduces kidney and gall stones by up to 30%
5. Reduces prostate cancer by up to 50% 17. Improves kidney blood flow, reducing
6. Reduces cancer rates in general including
renal failure
lung, ovarian, liver and bowel. 18. Reduces deep vein thrombosis by up to 50%
7. May enhance effectiveness of chemotherapy 19. Reduces common colds by up to 85%
20. Contains many vitamins, minerals, trace
whilst reducing chemotoxicity
8. Significantly increases natural testosterone elements, proteins and carbohydrates

production
9. Possesses anti-ageing properties
10. Reduces high blood pressure



Wine as a delivery medium

Resveratrol can be consumed in the form of tablets
or capsules and absorbed through the intestines.
In this case the Resveratrol in the gut gets taken to
the liver via the portal blood system and
metabolized, leaving very little in the circulation to
then reach the various cells of the body.
The best way to absorb Resveratrol is via the buccal
mucosa (lining of the mouth), which allows for direct
entry in to the blood stream. Absorption of
Resveratrol via the buccal mucosa is several times
better than intestinal absorption.
The normal resveratrol content of wine is 1-2
milligrams per litre for whites and 2-6mg/L for reds.
The antioxidants in wine are not stored in the body,
so it is regular consumption, in moderation, of wine
that delivers a significant dose of resveratrol.
Moderate consumption can be defined as a standard
750ml bottle of wine each day, shared between two
people, with women advised to drink a little less
than men.

A case for Resveratrol Enhanced Wines

The health benefits of wine are due mainly to: The first strategy employed was to manipulate the
1. Alcohol content vineyard by spraying it with water, causing the
2. Salicylate content grapes to generate more resveratrol in order to deal
3. Antioxidant content with the threat of fungal infections. This was
expensive, needed access to a lot of water and
So to make wine healthier, the level of these three caused a lot of fungal infection of grapes so this
components in wine could be raised. avenue was abandoned.
However, raising the alcohol content markedly is not Second, some researchers are using genetic
desirable because of the risk of alcohol abuse. manipulation to develop new varieties of Vitis
Furthermore, if the alcohol content becomes too vinifera grapes higher in resveratrol content, but this
high the resultant beverage becomes a fortified wine would require the engraftment of all vineyards over
(e.g. port, Muscat, tokay, brandy etc.). Raising the to these new varieties - a most expensive
level of salicylic acid is not desirable either as it undertaking.
would make the wine bitter. An option is to raise the Third, researchers have found ways to manipulate
antioxidant content. the winemaking process to raise the resveratrol level
Resveratrol is the main antioxidant in wine. by adding in different enzymes at fermentation time
There have been many attempts to raise the to release more resveratrol from the grape skin.
resveratrol level of wine in the past. Unfortunately, more tannins and pigments are also
released which make the resultant wine darker and
taste of tannins.

The winemaking process can also be modified to Resveratrol Molecular Structure
change the fining and filtering processes so that less
resveratrol in the wine is stripped out or removed. C14H12O3
If all these techniques are employed, at best the
resveratrol level could be increased by 50%, so the Resveratrol Chemical Formula
resveratrol content in a normal white wine would
go from 1 mg/L to 1.5 mg/L and in a red wine from
6 mg/L to 9 mg/L.
Although wine has inherent beneficial components
and characteristics, the wine industry is strictly
controlled to prevent the addition of exogenous
additives or components to wine. Thus, it has not
been possible to enhance many beneficial
characteristics of wine and still be able to market a
legitimate and approved wine.
The innovative development of the The Wine Doctor
wines involves a process for increasing the level of
resveratrol in wine whilst still meeting regulatory
and accepted wine industry standards.

"Wine is the thinking
person’s health drink."

– Dr. Philip Norrie

Invention of R.E.W.

Dr. Philip Norrie invented Resveratrol Enhanced
Wine in 2006 and shortly thereafter founded The
Wine Doctor label. Dr. Norrie gained his medical
degree from the University of New South Wales in
Sydney, Australia, and also completed a PhD on the
history of wine as a medicine.
To date, Dr. Norrie has published more than 18
books related to wine, and after more than 30 years
in general practice was compelled to create a wine
that had the potential of fulfilling its promise as a
truly preventative medicine.
Dr. Norrie combined his medical expertise and
winemaking knowledge to enable the development
of the world’s first, full strength, patented
Resveratrol Enhanced Wine. The Wine Doctor R.E.W.
process meets Australian food standards and
wine-labelling requirements because resveratrol is
a natural grape product and the enhanced
resveratrol is itself also naturally derived.
This means that for the first time white wine lovers
can now also achieve the same level of resveratrol
intake per glass as red wine drinkers.

Products of The Wine Doctor label

Premium R.E.W. “Elysium Series” (current)

2015 Shiraz, South Australia

Standard R.E.W. (current)

2015 Shiraz, Barossa Valley, South Australia
Made with fruit from our own Barossa Valley
vineyard, this wine exhibits ripe plum fruit with a
touch of oak complexity giving notes of spice, plum
and chocolate. The flavors of ripe plum continue to
the palate with spice and chocolate evident.
This Shiraz is balanced by firm but ripe tannins
making the wine approachable immediately.
Alcohol content 14.0%Vol.
Wine maker – Brian Light
Consume 1-4 glasses per day.
Resveratrol concentration: up to 100x that of standard
wines (verified by an independent research institute)





Concentrated R.E.W. (current)

ResElixir

A more concentrated and convenient version of the
original Resveratrol Enhanced Wines. Made from
100% Australian red wine, totally natural, produced
and bottled in Australia. The 30mLs of wine in each
bottle contains the equivalent amount of
Resveratrol contained in up to 10 normal bottles
(750mL) of wine. ResElixir was developed for
people who do not want to consume the standard
amount of wine but still receive the health benefits
of Resveratrol. Absorbed the most efficient way, via
the lining of the mouth, ResElixir is the perfect
Resveratrol delivery system. Production of ResElixir
is subject to the same stringent requirements as all
Australian wine products imposed by the Australian
Grape & Wine Authority (AGWA).

Each box contains 30x 30mL bottles.
Alcohol content 13.8%Vol.
Consume 1-2 bottles per day.

Organisation Tony Yew

Dr. Philip Norrie JP

MBBS, MD, MA, MSc, MSocSc(Hons), Managing Director,
PhD Nodens Group Pty Ltd
General Practitioner, 30 years of experience in investment
(37 years), Sydney. consulting and international trade
Conjoint Senior Lecturer, (South East Asia and Australia).
Faculty of Medicine, University of Previous business success owning
New South Wales. radiology and medical services
Vice Chairman, companies, as well as Australia's
Medical Advisory Committee, largest direct to consumer
Northern Cancer Institute, Sydney. supplements company.
Inventor & Joint Patent holder, Joint Patent Holder,
Resveratrol Enhanced Wines – Resveratrol Enhanced Wines - R.E.W.
R.E.W. Co Owner, The Wine Doctor label.
Co Owner, The Wine Doctor label.

Nodens Group Contact

2013 NSW Export Awards Tony Yew
Finalist - Export Council
of Australia. Managing Director,
Nodens Group Pty Ltd
Nodens Group is an P: +61 2 9113 0988
Australian wine producer M: +61 411 500 333
with offices in Sydney, E: [email protected]
Guangzhou City, as well as
warehouses and a showroom Dean Kilby
in the Free Trade Zone near
Huangpu port, Guangzhou. Sales & Marketing Manager,
The Wine Doctor & R.E.W.
Our wine operations are M: +61 499 791 949
concentrated in South E: [email protected]
Australia, including offices
and vineyards in McLaren
Vale and the Barossa Valley.





www.winedoctor.com.au
www.nodensgroup.com