Generic    Brand/Available Form                             Dose       Max/Day              Comments                                                                                         Cost/Day       Tier
                                                                                                                                                      ProCare HospiceCare Preferred Drug List$3
                                                        3.125-25mg     Cardiac (continued)                                                                                                             Tier 1D
41                                                      BID                                                                                                                                  ¢           CR:Tier 3D
Carvedilol Coreg, Coreg CR                                             50mg     Subcategory: Congestive Heart Failure, Ischemic                                                               Patch:     (Formerly
                 Tablet: 3.125, 6.25, 12.5, 25mg        0.1-0.8mg/day           Heart Disease, Abdominal Aortic Aneurysm (AAA),                                                               $7.73 -    Tier 1D)
                 Capsule, CR (BRAND): 10, 20, 40, 80mg  divided into            Severe Aortic Stenosis w/Angina                                                                               $18.13
                                                        2 doses                 Therapeutic Class: Beta Blocker                                                                              ¢         Tier 1D
                                                                                May mask symptoms of hypoglycemia, take with                                                                             Patch:
                                                        0.125-1.25mg            food.                                                                                                        $1 - $2     Tier 3D
                                                        daily
Clonidine  Catapres                                                    2.4mg    Subcategory: Congestive Heart Failure,                                                                                 Tier 1D
           Tablet: 0.1, 0.2, 0.3mg                      30-90mg PO
           Transdermal Patch: 0.1, 0.2, 0.3mg/24h       QID                     AbdominalAortic Aneurysm (AAA)                                                                                         Tier 1D
           patch                                                                Therapeutic Class: Alpha 2 Agonist Do not
                                                                                suddenly d/c drug as rebound hypertension may
                                                                                occur
Digoxin    Lanoxin                                                              Subcategory: Congestive Heart Failure, Severe
           Tablet: 0.125, 0.25mg                                                Aortic Stenosis w/CHF
           Elixer: 50mcg/mL                                                     Therapeutic Class: Cardiac glycoside
                                                                                Monitor signs/symptoms bradycardia, maintenance
                                                                                doses after morning
Diltiazem  Cardizem, Cardizem CD, LA,                                  360mg    Subcategory: Ischemic Heart Disease, Abdominal
           Cartia XT, Dilt-CD, Diltia XT
           Tablet: 30, 60, 90, 120mg                                            Aortic Aneurysm (AAA)
           Tablet, 24HR ER: 180, 240, 300, 360,                                 Therapeutic Class: Calcium Channel Blocker
           420mg
           Capsule, 12HR ER: 60, 90, 120mg                                      May cause constipation
           Capsule, 24HR ER: 120, 180, 240, 300,
           360, 420mg
Generic                                                                                                                                           ProCare HospiceCare Preferred Drug ListBrand/AvailableDoseMax/DayCommentsCost/Day Tier
Dipyridamole         Form
Doxazosin42
Enalapril                                                          Cardiac (continued)
Felodipine    Persantine                50-100mg            400mg    Subcategory: Congestive Heart Failure – Other               $2 - $3  Tier 1D
Fosinopril    Tablet: 25, 50, 75mg      TID                          Therapeutic Class: Antiplatelet - Give at least 1hr before
Furosemide                                                           meals; Give with warfarin or aspirin
              Cardura                   1-16mg              16mg     May cause orthostatic hypotension. Syncope or loss          $1 Tier 1D
              Tablet: 1, 2, 4, 8mg                                   of consciousness is possible with first dose or dose.       $2 Tier 1D
                                        5-40mg daily
              Vasotec                   in 2 divided doses  40mg     Subcategory: Congestive Heart Failure, Abdominal
              Tablet: 2.5, 5, 10, 20mg                               Aortic Aneurysm (AAA), Severe Aortic Stenosis
                                                                     Therapeutic Class: Angiotensin-Converting Enzyme (ACE)
                                                                     Inhibitors
                                                                     Monitor for signs/symptoms of angioedema. Cough common.
              Plendil                   2.5-20mg daily      10mg     Subcategory: Abdominal Aortic Aneurysm (AAA)                $2 Tier 1D
                                                                     Therapeutic Class: Calcium Channel Blocker                  $1 Tier 1D
              Tablet, ER: 2.5, 5, 10mg
                                                                     May cause peripheral edema
              Monopril                  5-80mg              80mg     Subcategory: Congestive Heart Failure, Abdominal
              Tablet: 10, 20, 40mg                                   Aortic Aneurysm (AAA), Severe Aortic Stenosis
                                                                     Therapeutic Class: Angiotensin-Converting Enzyme (ACE)
                                                                     Inhibitors
                                                                     Monitor for ACE inhibitor induced cough
              Lasix                     10-160mg            600mg    Subcategory: Congestive Heart Failure, Severe               ¢ Tier 1D
              Tablet: 20, 40, 80mg      daily-BID
              Solution, oral:                                        Aortic Stenosis w/CHF, Abdominal Aortic Aneurysm (AAA)
              10mgmL, 40mg/5mL                                       Therapeutic Class: Diuretics (loop)
                                                                     Monitor for hypokalemia. Anuria: contraindicated
Generic       Brand/Available Form              Dose     Max/Day              Comments                                                                                              Cost/Day    Tier
                                                                                                                                                      ProCare HospiceCare Preferred Drug ListHydralazine10-300mg$2Tier 1D
                      Apresoline                                  Cardiac (continued)                                                                                                        $1        Tier 1
43Hydrochlorothiazide Tablet: 10, 25, 50, 100mg        12.5-50mg                                                                                                                             $1        Tier 1D
Irbesartan                                             daily      300mg     Subcategory: Congestive Heart Failure, Abdominal                                                                 ¢         Tier 1D
                      Microzide, Hydrodiuril           75-300mg             Aortic Aneurysm (AAA)                                                                                            $         Tier 1D
Isosorbide Dinitrate  Tablet: 25, 50mg                 daily                Therapeutic Class: Alpha 1 Blocker
                      Capsule: 12.5mg                                       Monitor for postural hypotension.
Isosorbide                                             2.5-240mg            CrCl 10-50: give Q8h; CrCl <10: give Q8-16h
Mononitrate           Avapro
                      Tablet: 75mg, 150mg, 300mg       10mg BID   200mg     Subcategory: Abdominal Aortic Aneurysm (AAA),
                      Isordil                                               Severe Aortic Stenosis w/CHF, Congestive Heart Failure
                      Tablet, ER: 5, 10, 20, 30, 40mg                       Therapeutic Class: Diuretics (thiazide)
                      Tablet, SL: 2.5, 5mg
                                                                            Anuria: contraindicated
                      Imdur
                      Tablet: 10, 20mg                            300mg     Subcategory: Congestive Heart Failure, Abdominal
                      Tablet, ER: 30, 60, 120mg                             Aortic Aneurysm (AAA), Severe Aortic Stenosis
                                                                            Therapeutic Class: Angiotensin II Receptor
                                                                            Blockers (ARBs) – If intolerant to ACE Inhibitors
                                                                            Monitor for potassium retention and hypotension
                                                                  480mg     Subcategory: Congestive Heart Failure, Ischemic
                                                                  160mg ER  Heart Disease, Severe Aortic Stenosis w/CHF
                                                                            Therapeutic Class: Nitrates
                                                                            Short acting vasodilator. Monitor for postural
                                                                            hypotension.
                                                                  40mg      Subcategory: Congestive Heart Failure, Ischemic
                                                                  240mg ER
                                                                            Heart Disease, Severe Aortic Stenosis w/CHF
                                                                            Therapeutic Class: Nitrates
                                                                            Long acting vasodilator. Monitor for hypotension
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Isradipine
44Labetalol Dynacirc                     2.5-5mg                  Cardiac (continued)
            Capsule: 2.5, 5mg            BID
Lisinopril                                          10mg          Subcategory: Ischemic Heart Disease, Abdominal                         $3- $5   Tier 1D
Losartan    Trandate, Normodyne          200-400mg
            Tablet: 100, 200, 300mg      BID                      Aortic Aneurysm (AAA)
                                                                  Therapeutic Class: Calcium Channel Blocker May
            Prinivil, Zestril            10-40mg
            Tablet: 2.5, 5, 10, 20, 30,  daily                    cause constipation and peripheral edema
            40mg
                                         25-100mg   2400mg        Subcategory: Congestive Heart Failure, Ischemic                        $1 Tier 1D
            Cozaar                       in 1-2                   Heart Disease, Abdominal Aortic Aneurysm (AAA),
            Tablet: 25, 50, 100mg        divided                  Severe Aortic Stenosis w/Angina
                                         doses                    Therapeutic Class: Beta Blocker
                                                                  May mask symptoms of hypoglycemia.
                                                    80mg          Subcategory: Congestive Heart Failure, Abdominal                       $1 Tier 1D
                                                    40mg (renal)
                                                                  Aortic Aneurysm (AAA), Severe Aortic Stenosis
                                                                  Therapeutic Class: Angiotensin-Converting Enzyme (ACE) Inhibitors
                                                                  Monitor for cough and postural hypotension
                                                    100mg         Subcategory: Abdominal Aortic Aneurysm (AAA),                          $2 - $3  Tier 1D
                                                                  Congestive Heart Failure, Severe Aortic Stenosis
                                                                  Therapeutic Class: Angiotensin II Receptor
                                                                  Blockers (ARBs) – If intolerant to ACE Inhibitors
                                                                  Monitor for potassium retention
Metolazone Zaroxolyn                     2.5-20mg 20mg            Subcategory: Congestive Heart Failure, Abdominal                       $2       Tier 1D
                   Tablet: 2.5, 5, 10mg  daily                    Aortic Aneurysm (AAA), Severe Aortic Stenosis w/CHF
                                                                  Therapeutic Class: Diuretics (thiazide)
                                                                  Not a potent diuretic alone; used in conjunction with Lasix or Bumex;
                                                                  administer 30min prior to dose of Lasix or Bumex
Generic Brand/Available Form                   Dose      Max/Day                         Comments                                                                                            Cost/Day   Tier
                                                                                                                                                      ProCare HospiceCare Preferred Drug List$1 - $2   Tier 1D
                                            50-200mg                Cardiac (continued)
45                                          BID                                                                                                                                              $1        Tier 1D
Metoprolol   Lopressor,Toprol XL                         450mg      Subcategory: Congestive Heart Failure, Ischemic Heart Disease,                                                           $3        Tier 1D
             Tablet, as tartrate: 25, 50,   20-320mg     400mg XL   Abdominal Aortic Aneurysm (AAA), Severe Aortic Stenosis w/                                                               $2        Tier 1D
             100mg                          daily                   Angina                                                                                                                   $7        Tier 1D
             Tablet, as succinate, XL: 25,                          Therapeutic Class: Beta Blocker
             50, 100, 200mg                 20-40mg                 Sudden discontinuation can cause rebound angina.
                                            TID                     Monitor for hypotension.
Nadolol      Corgard                        IR: 10-20mg  320mg      Subcategory: Congestive Heart Failure, Ischemic Heart Disease,
             Tablet: 20, 40, 80, 160mg      TID ER:                 Abdominal Aortic Aneurysm (AAA), Severe Aortic Stenosis w/
                                            30-90mg                 Angina
                                            daily                   Therapeutic Class: Beta Blocker
                                            17-34mg                 Long acting beta blocker. Monitor for hypokalemia.
                                            daily
Nicardipine Cardene                                      120mg      Subcategory: Ischemic Heart Disease, Abdominal
                   Capsule: 20, 30mg
                                                                    Aortic Aneurysm (AAA)
                                                                    Therapeutic Class: Calcium Channel Blocker
                                                                    Can cause peripheral edema and constipation
Nifedipine   Procardia, Adalat                           IR: 180mg  Subcategory: Ischemic Heart Disease, Abdominal
             Capsule: 10, 20mg                           ER: 90mg
             Tablet, ER: 30, 60, 90mg                               Aortic Aneurysm (AAA)
                                                                    Therapeutic Class: Calcium Channel Blocker
                                                                    Take ER tablets on empty stomach. May cause constipation.
Nisoldipine  Sular                                       60mg       Subcategory: Abdominal Aortic Aneurysm (AAA),
             Tablet, ER: 8.5, 10, 17, 20,
             25.5, 30, 34, 40mg                                     Ischemic Heart Disease , Abdominal Aortic Aneurysm
                                                                    Therapeutic Class: Calcium Channel Blocker
                                                                    Give on empty stomach. May cause constipation & peripheral edema.
Generic                                                                                                                                            ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Nitroglycerin46                                                       Cardiac (continued)
Ointment
               Nitro-Bid                        0.5-2 inch  2-5 inch    Subcategory: Congestive Heart Failure, Ischemic                             $2 - $4  Tier 1D
Nitroglycerin  Topical: 2%                      Q4-6h       Q4hr
Patch                                                                   Heart Disease, Severe Aortic Stenosis w/CHF
                                                                        Therapeutic Class: Nitrates
Nitroglycerin
Sublingual                                                              Increase 0.5inch PRN. Include10-12h nitrate free interval
Potassium      Nitro-Dur                        0.1-0.6mg/  0.6mg/hr    Subcategory: Congestive Heart Failure, Ischemic                             $2 - $4  Tier 1D
Chloride
               Transdermal Patch: 0.1, 0.2, 0.4, hr                     Heart Disease, Severe Aortic Stenosis w/CHF
Propafenone                                                             Therapeutic Class: Nitrates
               0.6mg/hr
Propranolol                                                             Increase 0.5inch PRN. Include 10-12h nitrate free interval
               Nitrostat, NitroMist             0.3-0.6 mg  3 doses in  Subcategory: Congestive Heart Failure, Ischemic                             $2 Tier 1D
               Tablet: 0.3, 0.4, 0.6 mg         Q5 min      15 min
               Spray: 0.4 mg/actuation                                  Heart Disease, Severe Aortic Stenosis w/CHF
                                                                        Therapeutic Class: Nitrates
                                                                        Store tablets in original glass container and away from moisture and light
               K-Dur, Klor-Con                  20meq       100meq May cause diarrhea, nausea, vomiting or abdominal pain                           $1 Tier 1D
               Capsule, XR: 8, 10meq            2-5X daily
               Tablet, ER: 8, 10, 15, 20meq                 900mg       May cause bradycardia.                                                      $2 Tier 1D
               Solution, oral: 20, 40meq/15mL   150mg TID               Use with caution in patients taking methadone.                              $1 Tier 1D
                                                            HTN:        Hepatic impairment: decr. dose 70-80%
               Rythmol                          80-240mg    640mg
               Tablet: 150, 225, 300mg          BID         Angina:     Subcategory: Congestive Heart Failure
               Capsule, ER: 225, 325, 425mg                 320mg       Therapeutic Class: Beta Blocker
                                                                        Effective also for myoclonus.
               Inderal
               Tablet: 10, 20, 40, 60, 80mg
               Capsule, LA: 60, 80, 120, 160mg
               Solution, oral: 20, 40mg/5mL
Generic  Brand/Available Form             Dose       Max/Day                    Comments                                  Cost/Day Tier
Quinapril                                                                                                                                             ProCare HospiceCare Preferred Drug List
Ramipril                                                        Cardiac (continued)
47
              Accupril                         20-80mg    HTN: 80mg Long acting ACE inhibitor.                                 $1 - $2  Tier 1D
              Tablet: 5, 10, 20 40mg           daily      CHF: 40mg Cough side effect is common                                $3       Tier 1D
              Altace                           5mg BID    20mg         Subcategory: Congestive Heart Failure, Abdominal
              Capsule: 1.25, 2.5, 5, 10mg                 5mg (renal)  Aortic Aneurysm (AAA), Severe Aortic Stenosis
                                                                       Therapeutic Class: Angiotensin-Converting Enzyme
                                                                       (ACE) Inhibitors
                                                                       Increase dose Q3 weeks to target dose.
                                                                       CrCl <40: max 5mg/day
Spironolactone Aldactone                       20-200mg   400mg        Subcategory: Congestive Heart Failure, Severe           $1 Tier 1D
                        Tablet: 25, 50, 100mg  daily                   Aortic Stenosis w/CHF, Abdominal Aortic Aneurysm (AAA)
                                                                       Therapeutic Class: Diuretics (potassium sparing)
                                                                       Especially useful with ascites prevents third spacing;
                                                                       may cause constipation and hypotension.
                                                                       CrCl <10: contraindicated;
                                                                       anuria, acute renal impairment: contraindicated
Terazosin     Hytrin                           1-5mg QHS  20mg         First dose hypotension side effect; give QHS only       $2       Tier 1D
Torsemide     Capsule: 1, 2, 5, 10 mg                                                                                          $1 - $3  Tier 1D
                                               10-200mg   200mg        Subcategory: Congestive Heart Failure, Abdominal
              Demadex                          daily
              Tablet: 5, 10, 20, 100mg                                 Aortic Aneurysm (AAA), Severe Aortic Stenosis w/CHF
                                                                       Therapeutic Class: Diuretics (thiazide)
                                                                       May cause hypokalemia.
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                                     $5 Tier 1D
48                                                                   Cardiac (continued)
Valsartan  Diovan                                    HTN: 80-320mg   320mg    Subcategory: Congestive Heart Failure, Abdominal
           Tablet: 40, 80, 160, 320mg                daily                    Aortic Aneurysm (AAA), Severe Aortic Stenosis
                                                     CHF:                     Therapeutic Class: Angiotensin II Receptor
                                                     80-160mg daily           Blockers (ARBs) – If intolerant to ACE Inhibitors May
                                                                              be made into a suspension for patients unable to
                                                                              swallow
Verapamil  Calan                                     240-320mg       480mg    Subcategory: Abdominal Aortic Aneurysm (AAA),          $2 - $3  Tier 1D
Warfarin   Tablet: 40, 80, 120mg                     3-4 x day                Ischemic Heart Disease
           Tablet, ER (12h): 120, 180, 240mg         Divide dose              Therapeutic Class: Calcium Channel Blocker                       IR Form:
           Capsule, ER (24h AM): 120, 180,           BID if >240mg            Divide dose BID if >240mg/day. Do not crush ER                   Tier 2D
           240, 360mg                                daily                    tablets.
           Capsule, ER (24h PM): 100, 200,                                    Hepatic impairment: decr. dose 70%; Consider
           300mg                                                              alternate dosage form instead of ER
           Coumadin                                  Individualized  Based upon Subcategory: Cancer with PE/DVT (not preexisting)    $1 Tier 1D
           Tablet: 1, 2, 2.5, 3, 4, 5, 6, 7.5, 10mg                  INR level Requires monitoring by INR. Discontinue when oral     $4 Tier 2D
                                                                                     intake declines
Olmesartan Benicar                                   5-40mg daily    40mg     Subcategory: Congestive Heart Failure, Abdominal
                      Tablet: 5, 20, 40mg                                     Aortic Aneurysm (AAA), Severe Aortic Stenosis
                                                                              Therapeutic Class: Angiotensin II Receptor
                                                                              Blockers (ARBs) – If intolerant to ACE Inhibitors
                                                                              May cause potassium retention and hypotension.
Phytonadione Mephyton                                2.5-25mg daily  25mg/dose Subcategory: Congestive Heart Failure - Other         ¢ Tier 2D
(Tablet only) Tablet: 5mg                            PRN, PO only                    Dosage based upon INR                                           (Formerly
                                                                                                                                                     Tier 1D
Generic  Brand/Available Form      Dose           Max/Day              Comments                                                                                                        Cost/Day Tier
Telmisartan                                                                                                                                           ProCare HospiceCare Preferred Drug List$5 Tier 2D
                                                        Cardiac (continued)
Triamterene49                                                                                                                                                                                                (formerly
               Micardis                  20-80mg        160mg          Subcategory: Congestive Heart Failure, Abdominal                                                                                      Tier 1D)
Triamterene/   Tablet: 20, 40, 80mg      daily                                                                                                                                               $5 Tier 2D
HCTZ                                                                   Aortic Aneurysm (AAA), Severe Aortic Stenosis
Clopidogrel                                                            Therapeutic Class: Angiotensin II Receptor                                                                            ¢ Tier 2
Albuterol                                                              Blockers (ARBs) – If intolerant to ACE Inhibitors
               Dyrenium                  100mg BID      300mg          Subcategory: Abdominal Aortic Aneurysm (AAA),
               Capsule: 50, 100mg                                      Severe Aortic Stenosis w/CHF, Congestive Heart
                                                                       Failure
                                                                       Therapeutic Class: Diuretics (potassium sparing)
                                                                       Anuria: contraindicated
               Maxzide/Dyazide           25 mg/37.5mg   75/50mg        Triamterene is a potassium sparing diuretic
               Tablet: 25/37.5, 50/75mg  daily
               Capsule: 25/37.5mg                       75mg           Subcategory: Congestive Heart Failure – Other      $7                                                                 Tier 3D
                                         75mg daily                    Therapeutic Class: Antiplatelet Non-preferred      $3                                                                 Tier 1D
               Plavix
               Tablet: 75, 300mg
                                                        Pulmonary Disease
               Proventil,Ventolin        Neb: 1 vial    Neb: 10mg      Subcategory: COPD (Obstructive),
               Neb: 2.5mg/3mL (0.083%),  via neb Q1-4h  MDI: 12 puffs  Other (Restrictive/Neoplastic)
               5mgmL (0.5%)              PRN                           Monitor for agitation
               MDI: 90mcg/spray          MDI: 2 puffs                  May be used to treat hyperkalemia
                                         Q4-6h PRN
Generic                                                                                                                                        ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/DayTier
Ipratropium
50                 Atrovent                           Pulmonary Disease (continued)                                        $5                                                                Neb:Tier 1
Ipratropium/       Neb: 0.5mg/2.5ml (0.02%)                                                                                                                                                  MDI:Tier 3
Albuterol          MDI: 17mcg/spray                   Neb: 1 vial           Neb: 6 doses Subcategory: COPD (Obstructive)   $6                                                                Neb:Tier 1
                   DuoNeb, Combivent                  via neb Q6-8h PRN     MDI: 12 puffs Neb mixed with albuterol neb is  MDI:                                                              MDI:Tier 3
NaCl 0.9% sterile  Neb: 0.5mg/2.5mg/3mL               MDI: 2 puffs inh QID                                                 $14.07
for inhalation     MDI: 18mcg/90mcg/spray                                                      stable for 1 hour.
Theophylline
                   Bronchosaline                      Neb: 3mL inh QID      Neb: 6 doses Subcategory: COPD (Obstructive),
Beclomethasone     Neb: 0.9%
Arformoterol       Theo-Dur                           MDI: 1-2 puffs inh QID MDI: 12 puffs Other (Restrictive/Neoplastic)
                   Tablet, CR: 400, 600mg
Fluticasone        Capsule, ER: 100, 200, 300, 400mg  3mL Q4h               150meq   Subcategory: COPD (Obstructive)       $1                                                                Tier 1
                   Elixir: 800mg/15mL                 PRN                   600mg    Fluid intake is encouraged            $2                                                                Tier 1D
                   Qvar
                   MDI: 40, 80mcg/spray               200mg BID                      Geriatic goal serum concentration is
                   Brovana                                                           5-7mcg/ml
                   Neb: 15mcg/2mL
                                                      1-4 puffs inh Q12h    640mcg   Subcategory: COPD (Obstructive) $8 - $11                                                                Tier 2D
                   Flovent
                   DPI: 100, 250mcg/blister           2mL via neb Q12h      30mcq    Subcategory: COPD (Obstructive) $17                                                                     Tier 3D
                   MDI: 40, 110, 220mcg/spray                                        Long Acting Beta2 Agonist.                                                                              (formerly
                                                                                                                                                                                             Tier 2D)
                                                      DPI:1-2 puffs inh Q12h DPI: 1000mcg Subcategory: COPD (Obstructive) $11
                                                      MDI: 2 puffs inh Q12h MDI: 880mcg Inhaled steroid: Rinse mouth after use                                                               Tier 3D
                                                                                                                                                                                             (formerly
                                                                                                                                                                                             Tier 2D)
Generic       Brand/Available Form                                  Dose             Max/Day       Comments                                Cost/Day Tier
                                                                                                                                           $14 - $22 Tier 3D
                                                                                                                                                      ProCare HospiceCare Preferred Drug ListPulmonary Disease (continued)
Fluticasone/51Advair Diskus,Advair HFA                              1 puff inh       500/50 1      Subcategory: COPD (Obstructive)
Salmeterol    DPI: 100/50, 250/50, 500/50mcg/blister                Q12h             puff BID      Inhaled steroid: Rinse mouth after use
              MDI: 45/21, 115/21, 230/21mcg                                                        Not for acute attacks; dosage for
                                                                                                   COPD
Formoterol    Perforomist, Foradil                                  Neb: 2mL via     Neb: 40mcg    Subcategory: COPD (Obstructive) $16             Tier 3D
              Neb: 20mcg/2mL                                        neb inh Q12h     DPI: 2 caps   Long acting Beta2 agonist                       (formerly
              DPI: 12mcg/cap                                        DPI: 1 cap inh                                                                 Tier 2D)
                                                                    Q12h             Neb: 6 vials
Levalbuterol Xopenex, HFA                                                            MDI: 12       Subcategory: COPD (Obstructive)         $8 Tier 3D
                     Neb: 0.31, 0.63 (0.021%), 1.25mg/3mL (0.042%)  Neb: 1-2 vials   puffs                                                 (nebulizer)
                     MDI: 45mcg/spray                               via neb TID                                                            $2 (inhaler)
                                                                    PRN              50mcg inh
Salmeterol    Serevent Diskus                                       MDI: 2 puffs     Q12h          Subcategory: COPD (Obstructive)         $13     Tier 3D
Tiotropium    DPI: 50mcg/blister                                    inh Q4-6h PRN    1 inhalation  Long acting Beta2 Agonist               $18     Tier 3D
              Spiriva                                               1 puff inh                     Avoid combination with Combivent or             Tier 1
                                                                    Q12h                           DuoNeb
                                                                    1 cap inh daily
                                                                    Hepatic Disease
Bumetanide Bumex                                                    0.5-10mg/day     10mg          Monitor for hypokalemia; administer     ¢ - $1
                     Tablet: 0.5, 1, 2mg                            daily BID                      last dose before 4pm
Generic                                                                                                                                          ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayComments    Cost/Day     Tier
Cholestyramine                                                                                                                                                                                                                          $1- $2     Tier 1D
Furosemide52    Questran                                      Hepatic Disease (continued)                                                                                                    Dissolved in juice or water;               ¢          Tier 1
Metolazone      Powder, pkt: 4g cholestyramine / 9g powder                                                                                                                                   promotes formed stools;                    $1         Tier 1
                Powder, scoop: 4g cholestyramine / 9g powder  4g 1-4x daily  24g                                                                                                             useful in C.diff
Spironolactone  Lasix                                                                                                                                                                        Monitor for hypokalemia                    $1         Tier 1
                Tablet: 20, 40, 80mg                          10-160mg       600mg                                                                                                           Anuria: contraindicated
Torsemide       Solution, oral: 10mg/mL, 40mg/5mL             daily-BID      20mg                                                                                                                                                       $1- $3     Tier 1
Lactulose       Zaroxolyn                                                                                                                                                                    Not a potent diuretic alone; used in       $3         Tier 2
                Tablet: 2.5, 5, 10mg                          2.5-20mg                                                                                                                       conjunction with Lasix or Bumex;
Neomycin                                                      daily                                                                                                                          administer 30min prior to dose of          $10 - $30  Tier 2D
                                                                                                                                                                                             Lasix or Bumex
                Aldactone                                     20-200mg       400mg                                                                                                           Potassium sparing, especially useful with
                Tablet: 25, 50, 100mg                         daily                                                                                                                          ascites or CHF, prevents third spacing;
                                                                                                                                                                                             may cause constipation and hypotension
                Demadex                                       10-200mg       200mg                                                                                                           CrCl <10: contraindicated; anuria,
                Tablet: 5, 10, 20, 100mg                      daily                                                                                                                          acute renal impairment: contraindicated
                                                                             60mL                                                                                                            Thiazide diuretic. May cause hypokalemia.
                Constulose, Enulose, Generlac, Kristalose     15-30mL        (constipation)
                Solution, oral: 10g/15mL                      daily BID                                                                                                                      Reserve for patients with high ammonia
                Pwdr Pkt (BRAND): 10g/packet (30s),                                                                                                                                          levels
                20g/packet (30s)                              1000-3000mg PO 12000mg
                                                              Q6h x 5-6 days                                                                                                                 Renal impairment: Decrease dose
                Neo-Fradin
                Tablet: 500mg
Generic        Brand/Available Form            Dose         Max/Day            Comments                                   Cost/Day Tier
                                                                                                                                                      ProCare HospiceCare Preferred Drug List
                                               Hepatic Disease (continued)
53
Aminocaproic Amicar                            1-3g Q6hr    30gm               May give loading dose                      $32 - $64                                                          Tier 3D
acid Tablet: 500, 1000mg                                                                                                  $50                                                                (formerly
                                                                                                                                                                                             Tier 1D)
Rifaximin      Xifaxan                         550mg PO BID 1100mg             Reduces urease-producing bacterial flora,
               Tablet (BRAND): 200, 550mg                                      decreasing ammonia production                                                                                 Tier 3D
                                                          Parkinson’s Disease
Amantadine     Symmetrel                       100mg BID    400mg              Anticholinergic side effects               $2                                                                 Tier 1D
               Capsule: 100mg                                                  CrCl 30-50: 200mg x1, then 100mg Qday;
Benztropine    Tablet: 100mg                   1mg BID      6mg                CrCl 15-29: 200mg x1, then 100mg Q48h;     $1                                                                 Tier 1
Bromocriptine  Syrup: 50mg/5mL                 2.5mg daily  4mg (elderly)      CrCl<15: 200mg Q7 days                     $3                                                                 Tier 1D
                                                                               Anticholinergic side effects
Carbidopa/     Cogentin                                     100mg
Levodopa       Tablet: 0.5, 1, 2mg                                             Give with food
Selegiline
               Parlodel                        25/100 TID   200/2000           Dyskinesia side effects                    $2 - $4    Tier 1D
               Tablet: 2.5mg                   5mg BID      10mg               CrCl <50: decr. dose 0-50%
               Capsule: 5mg                                                                                               $4 - $5    Tier 1D
                                                                               Give w/breakfast and lunch
               Sinemet
               Tablet: 10/100, 25/100, 25/250
               Tablet, ER: 25/100, 50/200
               Eldepryl
               Capsule: 5mg
               Tablet: 5mg
Generic                                                                                                                                            ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/DayTier
Carbidopa/                                                                                                                                                                                   $12 -$20       Tier 2D
Levodopa/54                                                  Parkinson’s Disease (continued)
Entacapone                                                                                                                                                                                   $7 - $15       Tier 2D
             Stalevo                                         Based on     8 tabs      Swallow tablet whole; do not                                                                           $6 - $9        (Formerly Tier 1D
Entacapone   12.5: Carbidopa 12.5mg, levodopa 50mg, and      therapeutic  (6 tabs of  crush, chew or break.                                                                                                 Tier 2D (Formerly
Pramipexole  entacapone 200mg                                response     200         Separate dosing from iron                                                                              $7             Tier 1D)
             18.75: Carbidopa 18.75mg, levodopa 75mg, and                 strength)   supplements and multivitamins                                                                           XR: $6 - $12   ER Tablet:Tier 3D
Quetiapine   entacapone 200mg                                                         with minerals
             25: Carbidopa 25mg, levodopa 100mg, and                                                                                                                                                        IR:Tier 2
             entacapone 200mg                                                                                                                                                                                XR:Tier 3D
             31.25: Carbidopa 31.25mg, Levodopa 125mg,
             and entacapone 200mg
             37.5: Carbidopa 37.5mg, levodopa 150mg, and
             entacapone 200mg
             50: Carbidopa 50mg, levodopa 200mg,
             and entacapone 200mg
             Comtan                                          200mg        1600mg Give with levo/carbidopa dose
             Tablet: 200mg                                   4x daily
             Mirapex                                         0.125mg      4.5mg       Only adjust dosage Q5days
             Tablet: 0.125, 0.25, 0.5, 0.75, 1, 1.5mg        TID                      CrCl 35-59: start 0.125mg bid,
             Tablet, ER (BRAND): 0.375, 0.75, 1.5, 3, 4.5mg                           max 1.5mg BID;
                                                                                      CrCl 15-34: start 0.125mg Qday,
                                                                                      max 1.5mg
                                                                                      Qday; CrCl <15: not defined
             Seroquel, Seroquel XR                           25-50mg      800mg       Preferred in Parkinson’s disease
             Tablet: 25, 50, 100, 200, 300, 400mg            Q8-12h
             Tablet, XR: 50, 150, 200, 300, 400mg
Generic              Brand/Available Form              Dose    Max/Day                    Comments                             Cost/Day                                                Tier
Ropinirole
                 Requip
                 Tablet: 0.25, 0.5, 1, 2, 3, 4, 5mg
                 Tablet, ER: 2, 3, 4, 6, 8, 12mg
                                                                                                                                                      ProCare HospiceCare Preferred Drug ListParkinson’s Disease (continued)
55                                                           3-6mg TID 24mg                     Give with food                       $8 - $15                                                Tier 2D
                                                                                                                                                                                             (Formerly1D)
                                                                                                                                                                                              ER Tablet:
                                                                                                                                                                                              Tier 3D
Cholestyramine   Questran                                             Renal Disease             Dissolved in juice or water;         $3 - $6                                                 Tier 1
                 Powder, pkt: 4g cholestyramine/9g powder    4g 1-4x daily 24g                  promotes formed stools; useful in                                                            Tier 1
Methadone (CII)  Powder, scoop: 4g cholestyramine/9g                                            C.diff                                                                                       Tier 1
                 powder                                                                                                                                                                      Tier 3D
Paroxetine                                                   Individualized N/A                 Excellent for nociceptive and        ¢                                                       Tier 3D
                 Dolophine                                                                      neuropathic pain and for patients    $2
Epoetin          Solution, oral, as hydrochloride: 5mg/5mL;  10-40mg daily 50mg                 with renal or hepatic impairment;
Oxycodone SR     10mg/5mL                                                       40mg (elderly,  call clinical pharmacist for dosage
(CII)            Tablet: 5, 10mg                                                renal/hepatic)
                                                                                                Useful if renal, opioid, or hepatic
                 Paxil                                                                          induced itch
                 Tablet: 10, 20, 30, 40mg
                 Tablet, ER: 12.5, 25, 37.5mg                50-100  1500 units/kg              Monitor for thrombotic side effects $3 - $52
                 Suspension: 10mg/5mL                                                           DO NOT CRUSH; non-preferred $4 - $28
                                                             units/kg 3x/wk 3x /week
                 Procrit, Epogen
                 Injection: 2000-10000 units/mL              Dosed   N/A
                                                             Q12h
                 Oxycontin
                 Tablet, ER/CR: 10, 15, 20, 30,40, 60, 80mg
Generic                                                                                                                                               ProCare HospiceCare Preferred Drug ListBrand/Available FormDose Max/DayCommentsCost/DayTier
56                                                          SYMPTOM MANAGEMENT                                                      ¢ - $2                                                   Tier 1
                                                                         Anorexia
                                                                                                                                    $2 - $3                                                  Tab:Tier 1
Dexamethasone   Decadron                                    2-16mg  40mg     GI upset, use with caution for patients with diabetes  Soltab: $5                                               Soltab:Tier 3
                Solution, oral: 1mg/mL                      BID              due to resultant hyperglycemia. Give
Mirtazepine     Tablet: 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6mg                   last dose by 2pm to avoid steroid-induced insomnia.
Prednisone      Remeron, Remeron SolTab                     7.5-30mg 45mg    Also expected to improve sleep and mood
                Tablet: 7.5, 15, 30, 45mg                   QHS
Cyproheptadine  SolTab (ODT): 15, 30, 45mg
                                                            5-80mg 80mg      GI upset, use with caution in patients with diabetes ¢             Tier 1
Megestrol       Deltasone                                   4 x daily
Acetate         Solution, oral: 1mg/mL
                Tablet: 1, 2.5, 5, 10, 20, 50mg             4mg daily- 16mg  Administer at bedtime to start                         $1.50       Tier 2
                                                            4x daily
                Periactin
                Solution, oral: 2mg/5ml                     400-    800mg    Promotes clot formation especially in                  $11 Tier 3
                Tablet: 4mg                                 800mg            nonambulatory
                                                            daily
                Megace
                Suspension, oral, as acetate: 40mg/mL
                ES (BRAND): 125mg/mL
                Tablet: 20, 40mg
                                                                    Anxiety/Agitation
Alprazolam      Xanax                                       0.25-1mg 4mg     May be given PO or SL; avoid or reduce dose in         $2          Tier 1
(CIV)           Tablet: 0.25, 0.5, 1, 2mg                   Q4-6h            patients with liver disease
                Tablet, ER: 0.5, 1, 2, 3mg                                                                                                      ODT/ER:
                ODT: 0.25, 0.5, 1, 2mg                                                                                                          Tier 3
                Solution, oral: 1mg/mL
Generic         Brand/Available Form              Dose                Max/Day      Comments                                                                                            Cost/Day   Tier
                                                                                                                                                      ProCare HospiceCare Preferred Drug ListChlorpromazine$4Tier 1
                Thorazine                               Anxiety/Agitation (continued)                                                                                                        $2
57Clonazepam    Tablet: 10, 25, 50, 100, 200mg                                                                                                                                               $1        Tier 1
(CIV)                                                   10-50mg             1000mg       May be given PO, SL, PR; more sedating; avoid in                                                    $2        ODT:
                Klonopin                                Q4-6h                            patients with Parkinson’s disease                                                                             Tier 3
Diazepam (CIV)  Tablet: 0.5, 1, 2mg                                                      May cause orthostatic hypotension                                                                   $1        Tier 1
                ODT wafer: 0.125, 0.25, 0.5, 1, 2mg
Divalproex                                              Anxiety:            4mg          Long-acting benzodiazepine; should not be used                                                                Tier 1
Sodium          Valium                                  1mg/day             (anxiety)    in combo with short-acting benzodiazepine
                Tablet: 2, 5, 10mg                      Seizure: 0.5mg TID  20mg                                                                                                                       Tier 1
Haloperidol     Solution, oral: 5mg/5mL, 5mg/mL         and titrate         (seizure)
                Depakote, Depakote Sprinkles                                                                                                                                                           Tier 1
Hydroxyzine     Tablet, DR: 125, 250, 500mg             2-10mg                           May be given PO, SL, PR; long half-life; use with
                Tablet, ER: 250, 500mg                  Q6-12h                           caution in elderly w/ liver disease; DIASTAT
                Capsule, DR: 125mg                                                       RECTAL GEL: NON-FORMULARY
                Haldol                                  15mg/kg/day         60mg/kg/day  Give with food; may open and sprinkle capsules
                Tablet:0.5, 1, 2, 5, 10, 20mg                                            on food. Divalproex sodium ER and DR tabs not
                Solution as lactate, oral: 2mg/mL                                        bioequivalent; incr. total daily dose by 8-20% if
                Solution, injection as lactate: 5mg/mL                                   switching from DR tab to ER tab.
                Atarax,Vistaril                                                          Hepatic dz/significant impairment: contraindicated
                Capsule as pamoate:25, 50, 100mg
                Tablet, HCl: 10, 25, 50mg               0.5-5mg             100mg        Can be given PO, SL, PR, IM; useful when
                Solution, oral: 10mg/5mL                Q6-12h                           benzodiazepines fail; do not use in patients with
                                                                                         Parkinson’s; low sedation
                                                        10-50mg             600mg        May cause drowsiness; use with caution in the       $3
                                                        Q4-6h                            elderly; useful in patients with Parkinson’s
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/DayTier
                                                                                                                                                                                             $2        Tier 1
58                                                        Anxiety/Agitation (continued)
Lorazepam      Ativan                                     0.5-2mg        10mg         Intermediate-acting benzodiazepine; may be given
(CIV)          Tablet: 0.5, 1, 2mg                        Q4-6h                       PO, SL, PR, SQ, IM; reduce dose if liver disease
               Solution, oral: 2mg/mL                                                 present
Oxazepam       Solution, injection: 2mg, 4mg/mL
(CIV)                                                     10mg           60mg/kg/day  Intermediate-acting benzodiazepine; may cause                                                          $3        Tier 1
Phenobarbital  Serax                                      Q8-14h                      paradoxical reaction in the elderly                                                                    $1        Tier 1
(CIII)         Capsule: 10, 15, 30mg                      60-100mg       60mg         May be given PO, PR, IM; long half-life allows less
                                                          daily BID-TID  800mg        frequent dosing                                                                                        $3        Tier 1
Valproic Acid  Luminal                                                   16mg         CrCl <10: give Q12-16h
               Tablet: 15, 16, 30, 32, 60, 65, 97, 100mg  250mg                       Drug levels required for seizures only; DO NOT                                                         $2 - $3   Tier 2
               Elixir: 20mg/5mL                           QHS x 7 days,               CRUSH ER FORMS; Depakene may be given                                                                  $7        IR:Tier 2
                                                          then 500mg                  rectally                                                                                               XR: $6 -  XR:Tier 3
               Depakene                                   QHS                                                                                                                                $12       Tier 2
               Syrup, as valproic acid: 250mg/5mL         20 - 30mg/day               Start: 7.5mg PO BID, then incr. 5mg/day Q2-3                                                           $7 - $21
               Capsule, as valproic acid: 250mg           BID-TID                     days; Severe renal/hepatic impairment: Avoid Use
                                                          25-50mg                     Preferred in Parkinson’s disease
Buspirone      Buspar                                     Q8-12h
Quetiapine     Tablet: 5, 7.5, 10, 15, 30mg                                           Preferred atypical antipsychotic
                                                          1-3mg BID
Risperidone    Seroquel, Seroquel XR
               Tablet: 25, 50, 100, 200, 300, 400mg
               Tablet, XR: 50, 150, 200, 300, 400mg
               Risperdal
               Tablet: 0.25, 0.5, 1, 2, 3, 4mg
               Solution, oral: 1mg/mL
               ODT: 0.25, 0.5, 1, 2, 3, 4mg
Generic      Brand/Available Form              Dose        Max/Day            Comments                               Cost/Day       Tier
Olanzapine
Paliperidone    Zyprexa, Zyprexa Zydis                                                                                                 Tier 3
                Tablet: 2.5, 5, 7.5, 10, 15mg, 20mg                                                                                    (Formerly
                ODT: 5, 10, 15, 20mg                                                                                                   Tier 2)
                Invega                                                                                                                 Tier 3
                Tablet, ER: 1.5, 3, 6, 9mg
                                                                                                                                                      ProCare HospiceCare Preferred Drug ListAnxiety/Agitation (continued)
59                                                    2.5-5mg     20mg     May cause hyperglycemia; risperidone is          $13 - $39
                                                      daily                preferred                                        ODT:
                                                                                                                            $21 -$40
                                                      6mg daily   12mg     Non-preferred, structurally similar to risperidone. $19
                                                                           CrCl 50-79: start 3mg Qam; max 6mg/day;
                                                                           CrCl 10-49: start 1.5mg Qam; max 3mg/day
Oxybutynin      Ditropan, Ditropan XL                 IR: 2.5mg   Bladder Spasm                                             $2 IR:Tier 1
Tolterodine     Syrup: 5mg/5mL                        Q8-12hr                                                               Patch: $10 XL:Tier 2
                Tablet, IR: 5mg                       XL: 5-15mg   IR: 20mg Subcategory: Bladder Cancer
                Tablet, XL: 5, 10, 15mg               daily        ER: 30mg Geriatric dose is 2.5mg BID                                      Patch:Tier 3
                Transdermal Patch: 3.9mg/day
                                                      4mg/day     4mg Subcategory: Bladder Cancer                           $6 Tier 2
                Detrol                                            2mg (renal) CrCl <30: 1mg BID                                              LA:Tier 3
                Tablet: 1, 2mg
                Capsule, LA: 2, 4mg
                                                                  Congestion
Diphenhydramine Benadryl                              25-100mg    400mg    Use with caution in elderly patients; causes     ¢          Tier 1
                            Capsule/Tablet: 25, 50mg  QHS and/or           confusion/drowsiness/dizziness; will not affect
                            Elixir: 12.5mg/5mL        Q4-6h PRN            blood pressure
Generic                                                                                                                                         ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Guaifenesin                                                                                                                 $2 Tier 1
60                                                          Congestion (continued)  Subcategory: COPD (Obstructive),
NaCl 0.9% sterile                                                                   Other (Restrictive/Neoplastic)
for inhalation     Robitussin                               10-30mL Q4h 2400mg      SVN only – No inhalers unless has
Oxymetazoline      Tablet: 200, 400mg                                               obstructive component.
Pseudoephedrine    Liquid: 100mg/5mL                                                Monitor for agitation and hypokalemia;
                   Solution, oral: 100mg/5mL, 100mg/6.25mL                          may be used to treat hyperkalemia.
Guaifenesin LA     Solution, oral drops: 50mg/mL                                    Subcategory: COPD (Obstructive)
Bisacodyl                                                                           Fluid intake is encouraged
                   Bronchosaline                            3mL Q4h        150meq   Do not use for more than 3-5 days;      $1      Tier 1
                   Neb: 0.9%                                PRN            240mg    may cause rebound congestion                    Tier 1
                                                                                                                            $5 per
                   Afrin                                    2-3 sprays              May increase blood pressure or cause    bottle  Tier 1
                   Solution, intranasal, as hydrochloride   each nostril,           agitation; do not take at bedtime due
                   [spray]: 0.05 %                          Q12h                    to drug-induced insomnia                $1
                   Sudafed                                  30-60mg                 Subcategory: COPD (Obstructive)
                   Tablet: 30, 60mg                         Q4-6h                   Do not crush; encourage fluid intake
                   Tablet, ER: 120, 240mg
                   Syrup: 15, 30mg/5mL                      1-2 tabs BID 2400mg     Can be used daily or PRN                ¢ Tier 2
                   Mucinex                                       Constipation                                               ¢ - $1  Tier 1
                   Tablet, ER: 600mg                        5-10mg QHS 30mg
                   Dulcolax
                   Suppository: 10mg
                   Tablet: 5mg
Generic                Brand/Available Form  Dose             Max/Day                 Comments              Cost/Day Tier
                                                                               Stool softener only                ¢ Tier 1
Docusate       Colace                                                          May cause “fatty” appearing stool  ¢ Tier 1
                                                                                                                                                      ProCare HospiceCare Preferred Drug ListCapsule, as sodium: 50, 100, 250mgConstipation (continued)
Glycerin       Liquid: 150mg/15mL
61Suppository  Sani-Supp                           50-500mg
                                                   daily in 1-4
Magnesium      Magnesium Citrate                   divided doses
Citrate        Bottle: 300mL
                                                   1 supp daily 2 supps
Magnesium      Milk of Magnesia
Hydroxide      Liquid, oral: 400, 800mg/5mL        1 bottle PRN 300mL          May keep chilled in refrigerator;  $3/bottle Tier 1
               Tablet, chewable: 311mg                                         300mL= 235meq                      ¢ Tier 1
Mineral Oil    Mineral Oil                         15-30mL          60mL       Magnesium = 2.8g
                                                   daily
                                                                               Caution in patients with renal
                                                                               impairment
Psyllium (Fiber) Metamucil                         15-45mL/day      118mL      Given as an enema only; oral use   ¢       Tier 1
                          Powder: 3.4g per dose    divided Q8-      30g        may cause pneumonitis              ¢       Tier 1
                                                   24h                                                            ¢ - $1  Tier 1
                                                                               Use with caution in patients
                                                   2 Tbsp. daily -             with poor fluid intake; may cause
                                                   BID                         obstruction
Senna          Senna                               2 tabs BID       8 tablets  May cause abdominal cramping
               Tablet: 8.6mg                                                   when used alone
Generic                                                                                                                                       ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayComments Cost/Day Tier
Sennosides/62                                                    Constipation (continued)                                                                                                    Typically a first line therapy; should
Docusate Sodium                                                                                                                                                                              be started in all patients on opioids
Sodium Phosphate     Senna S, Senokot S, Senna Plus              1-2 tabs daily  8 tablets                                                                                                   May cause electrolyte imbalance         ¢        Tier 1
Enema/                                                                                                                                                                                                                               $3.65    Tier 1
Bisphosphonate       Tablet: docusate 50mg and sennosides 8.6mg                                                                                                                              Osmotic stool softener
Enema                                                                                                                                                                                        Reserve for patients with high
Sorbitol 70% Soln    Fleet Enema                                 1 enema PR daily 1 enema daily                                                                                              ammonia levels
Lactulose            Sorbitol 70% Soln                           15-30mL daily   150mL                                                                                                       Dissolve in 4-8oz of liquid prior to    ¢ Tier 1
                     Solution, oral: 70% (30mL, 480mL, 3840mL)   BID                                                                                                                         admin.                                  $3 Tier 2
Polyethylene Glycol                                              15-30mL daily   60mL                                                                                                        May take 2-4 days to produce BM
(PEG) 3350           Constulose, Enulose, Generlac,              BID             (constipation)
                     Kristalose                                                                                                                                                              Swallow caps whole
Benzonatate          Solution, oral: 10g/15mL                    17g daily                                                                                                                   Contains alcohol                        $1 Tier 2
                     Pwdr Pkt (BRAND): 10g/packet (30s),
Dextromethorphan     20g/packet (30s)
                     MiraLax OTC
                     1 bottle: 527g
                                                      Cough-Dry; Non-Productive
                     Tessalon Perles                             100mg TID       600mg                                                                                                                                               $4 - $6  Tier 1
                     Capsule: 100, 200mg                                                                                                                                                                                             $2       Tier 1
                                                                 5-10mL Q4 PRN   120mg
                     Delsym (ER)                                 Delsym: 10mL
                     Liquid: 10mg/5mL, 30mg/5mL (ER)             Q12 PRN
Generic        Brand/Available Form                   Dose        Max/Day                   Comments                           Cost/Day Tier
                                                                                                                                                      ProCare HospiceCare Preferred Drug List
                                                   Cough-Dry; Non-Productive (continued)
63
Hydrocodone/   Hydromet                               5mL Q4-6H 30mL                                                           $1 - $5  Tier 1
                                                      PRN                                                                      $2       Tier 1
Homatropine (CIII) Syrup, oral; 5-1.5mg/5mL
Paroxetine     Paxil                                  10-40mg    50mg                     Mechanism for cough unknown;
               Tablet: 10, 20, 30, 40mg               daily      40mg (elderly,           effective for cough after 1-3 doses
               Tablet, ER: 12.5, 25, 37.5mg                      renal/hepatic)
               Suspension: 10mg/5mL
Promethazine/  Phenergan with Codeine                 5mL PO     30mL                     Take with food/water to decrease     $2 - $3 Tier 1
Codeine (CV)   Syrup, oral; 6.25-10mg/5mL                                                 GI upset                             $0.50 - $1 Tier 1
                                                      Q4-6H PRN                                                                $2 Tier 1
                                                   Cough-Wet; Productive
Guaifenesin/   Robitussin AC, Guaiatussin AC, Iophen  10mL Q4H 60mL                       Encourage fluid intake,
Codeine        C-NR, Cheratussin AC                   PRN                                 recommend diabetic tussin for
                                                                                          patients with DM
               Solution/Syrup oral: 100mg/10mg/5mL
Guaifenesin/   Robitussin DM                          10mL       2400mg day               Encourage fluid intake,
                                                                                          recommend diabetic tussin for
Dextromethorphan Solution, oral: 100mg/10mg/5mL       Q4hr PRN guaifenesin                patients with DM
                                                      Depression
Citalopram     Celexa                                 10-40mg    40mg                     Preferred over Lexapro (its          $2 Tier 1
               Tablet: 10, 20, 40mg                   QAM                                                                      $1 Tier 1
               Solution, oral: 10mg/5mL                          20mg (pts >60 yo) isomer)
Desipramine    Norpramin                              10-150mg   300mg                    Also expected to improve sleep
               Tablet: 10, 25, 50, 75, 100, 150mg     QHS                                 and mood; least anticholinergic
                                                                                          effect; max in elderly is 150mg per
                                                                                          day
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDose Max/DayCommentsCost/DayTier
64                                                           Depression (continued)
Dexamethasone    Decadron                                    2-16mg  40mg         Subcategory: COPD (Obstructive)               ¢ - $2    Tier 1
                 Solution, oral: 1mg/mL                      BID                  GI upset, use with caution for patients with
                 Tablet: 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6mg                       diabetes due to resultant hyperglycemia.
                                                                                  Give last dose by 2pm to avoid steroid-
                                                                                  induced insomnia.
                                                                                  Use in patients with CHF or water retention.
Doxepin          Sinequan                                    10-30mg 300mg        Caution in elderly; OK if bedbound; causes    $1 Tier 1
Fluoxetine       Capsule: 10, 25, 50, 75, 100, 150mg         QHS                  drowsiness
                 Solution, oral: 10mg/mL
Methylphenidate  Prozac                                      20-60mg 80mg         Long half-life; increases risk of falls       $2 Tier1
(CII)            Tablet: 10, 20mg                            daily
                 Capsule: 10, 20, 40mg                                                                                                         DR Capsule:
Mirtazepine      Capsule, DR: 90mg                                                                                                             Tier 3
Nortriptyline    Solution, oral: 20mg/5mL
                 Ritalin                                     5-10mg 60mg          May be used alone or in combination with      ¢ - $1    Tier 1
                 Tablet: 5, 10, 20mg                         Daily-BID (ER tab/   SSRI or TCA; schedule last dose before 2pm
                 Tablet, 12-24h ER: 10, 20mg                                      to lessen the risk of drug-induced insomnia;  $2 - $3 Tab:Tier 1
                 Capsule, 24h LA (BRAND): 10, 20, 30, 40mg                  cap)  caution in patients with cardiac issues or    SolTab: $5 SolTab:Tier 3
                 Solution, oral: 5, 10mg/5mL                                      uncontrolled HTN
                 Remeron, Remeron SolTab                     7.5-30mg 45mg        Also expected to improve sleep and mood
                 Tablet: 7.5, 15, 30, 45mg                   QHS
                 SolTab (ODT): 15, 30, 45mg                                       Also expected to improve sleep and mood; $1             Tier 1
                 Pamelor                                     10-150mg 150mg       start at lowest dose possible
                 Capsule: 10, 25, 50, 75mg                   QHS
                 Solution, oral: 10mg/5mL
Generic          Brand/Available Form              Dose           Max/Day            Comments                                         Cost/Day Tier
Paroxetine                                                                                                                                 $2 Tier 1
                                                                                                                                                      ProCare HospiceCare Preferred Drug ListPaxilDepression (continued)
Prednisone     Tablet: 10, 20, 30, 40mg
65             Tablet, ER: 12.5, 25, 37.5mg             10-40mg        50mg               Mechanism for cough unknown; effective for
Sertraline     Suspension: 10mg/5mL                     daily          40mg (elderly,     cough after 1-3 doses
Trazodone      Deltasone                                               renal/hepatic)
Amitriptyline  Solution, oral: 1mg/mL
Bupropion      Tablet: 1, 2.5, 5, 10, 20, 50mg          5-80mg         80mg               Subcategory: COPD (Obstructive)                  ¢                                                 Tier 1
HCl                                                     4x daily                          GI upset, use with caution in patients with      $2 - $4                                           Tier 1
               Zoloft                                                                     diabetes due to resultant hyperglycemia.
               Tablet: 25, 50, 100mg                    25-200mg       200mg              Give last dose by 2pm to avoid steroid-induced
               Solution, oral: 20mg/mL                  QAM                               insomnia. Do NOT use in patients with CHF or
               Desyrel                                                                    water retention (use dexamethasone instead).
               Tablet: 50, 100, 150, 300mg
                                                                                          Use lower doses in patients with hepatic
               Elavil                                                                     impairment
               Tablet: 10, 25, 50, 75, 100, 125, 150mg
               Budeprion SR/XL,Wellbutrin               25-100mg       400mg              Useful to treat insomnia                         ¢ - $1   Tier 1
               SR/XL, Zyban                             QHS            (depression)
               Tablet: 75, 100mg                                       200mg (insomnia)   Also expected to improve sleep and mood;         ¢ - $1   Tier 2
               Tablet, SR (12H): 100, 150, 200mg        10-15mg                           increases risk of falls                          $3 - $4  Tier 2
               Tablet, XL (24H): 150, 300mg             QHS            300mg              ER Form: Do not cut/crush/chew
                                                                                          Severe cirrhosis: max 75mg/day, 100mg ER daily,
                                                        IR: 100mg TID  IR: 150mg/dose     or 150mg ER Q48h
                                                        SR, 12H:       450
                                                        150mg BID      SR: 400mg
                                                        XL, 24H:       XL: 450mg
                                                        300mg QAM
Generic                                                                                                                                         ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Duloxetine
Venlafaxine66   Cymbalta                              Depression (continued)
                Capsule, DR (BRAND): 20, 30, 60mg
Bismuth                                                               60mg daily       120mg           Useful to treat neuropathic pain     $6       Tier 2
Subsalicylate                                                                                          Do not cut/crush/chew/sprinkle       $3 - $4  Tier 2
Cholestyramine  Effexor                                               IR: 37.5 - 75mg  IR: 375mg       CrCl <30: avoid use
Diphenoxylate/  Tablet: 25, 37.5, 50, 75, 100mg                       BID-TID          ER: 225mg
Atropine (CV)   Tablet, ER: 37.5, 75, 150, 225mg                      ER: 75 - 225mg                   Give with food
                Capsule, ER: 37.5, 75, 150mg                          daily            8 tabs          Do not cut/crush/chew ER form
Loperamide                                                            Diarrhea/Gas                     CrCl 10-70: decr. Dose 25-50%
                Pepto Bismol, Kaopectate                              524mg Q 30-60    24g             CrCl <10: decr. Dose 50%
                Tablet, chewable: 262mg                               min PRN
                Liquid, oral: 262mg/15mL                                               20mg            May cause stool to appear            ¢ - $2                                           Tier 1
                                                                      4g 1-4x daily    (diphenoxylate                                                                                        Tier 1
                Questran                                                               component)      black/tarry                                                                           Tier 1
                Powder, pkt: 4g cholestyramine/9g powder              5mg
                Powder, scoop: 4g cholestyramine/9g powder            (diphenoxylate   16mg            Avoid when C.diff infection present
                                                                      component)
                Lomotil                                               1-4x daily PRN                   Dissolved in juice or water;         $1 - $2
                Tablet: Diphenoxylate hydrochloride 2.5mg and                                          promotes formed stools; useful
                atropine sulfate 0.025mg                              4mg x1                           in C.diff
                Solution, oral: Diphenoxylate hydrochloride 2.5mg     And then
                and atropine sulfate 0.025mg/5mL                      2mg PRN                          Avoid when C.diff infection          $1 - $5
                                                                                                       present
                Imodium
                Capsule/Tablet: 2mg                                                                    Avoid when C.diff infection          ¢ - $1   Tier 1
                Solution, oral, as hydrochloride: 1mg/5mL, 1mg/7.5mL                                   present
Generic                                                                                                                                           ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Simethicone                                                                                                                      ¢ Tier 1
67           Mylicon                                      Diarrhea/Gas (continued)       Opium Tincture contains 25 times
Opium        Tablet, chewable: 80mg, 125mg               40-125mg 4x daily 500mg         more morphine than paregoric            $3 - $13  Tier 2
Tincture     Softgel: 125mg, 166mg, 180mg                                                                                                  (Formerly
(CIII)       Suspension, oral drops: 40mg/0.6mL (30mL)   Doses                           Subcategory: COPD (Obstructive),                  Tier 1)
                                                         expressed in mg:                Other (Restrictive/Neoplastic) Monitor
Thick-It     Opium Tincture                              6mg of undiluted                for agitation
             Tincture 10%, oral: w/ anhydrous morphine   opium tincture                  May be used to treat hyperkalemia
Albuterol    10mg/mL [0.6mL = to morphine 6mg; contains  (10mg/mL) 4x daily              May be given PO or SL; avoid or
             ethanol 19%]                                                                reduce dose in patients with liver
Alprazolam                                                                               disease
(CIV)                                                              Dysphagia
             Thickening Agent                            1-4 TBSP             None                                               $2 Tier 1
             8oz can
                                                                                                                                 $3 Tier 1
                                                         Dyspnea/Shortness of Breath
                                                                                                                                 $2 Tier 1
             Proventil,Ventolin                          Neb: 1 vial via      Neb: 10mg                                                          ODT/ER:
             Neb: 2.5mg/3mL (0.083%), 5mg/mL (0.5%)      neb Q1-4h PRN        MDI: 12                                                            Tier 3
             MDI: 90mcg/spray                            MDI: 2 puffs         puffs
                                                         Q4-6h PRN
             Xanax
             Tablet: 0.25, 0.5, 1, 2mg                   0.25-1mg             4mg
             Tablet, ER: 0.5, 1, 2, 3mg                  Q4-6h
             ODT: 0.25, 0.5, 1, 2mg
             Solution, oral: 1mg/mL
Generic                                                                                                                                        ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Dexamethasone
68                                                             Dyspnea/Shortness of Breath (continued)
Ipratropium
                   Decadron                                     2-16mg BID 40mg           GI upset, use with caution for patients      ¢ - $2                                                Tier 1
Ipratropium/       Solution, oral: 1mg/mL                                                 with diabetes due to resultant
Albuterol          Tablet: 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6mg                             hyperglycemia. Give last dose by 2pm
                                                                                          to avoid steroid-induced insomnia.
                   Atrovent                                     Neb: 1 vial via  Neb: 6 doses Subcategory: COPD (Obstructive)          $5 Neb:Tier 1
                   Neb: 0.5mg/2.5ml (0.02%)                     neb              MDI: 12 puffs Neb mixed with albuterol neb is stable
                   MDI: 17mcg/spray                             Q6-8h PRN                                                                              MDI:
                                                                MDI: 2 puffs                       for 1 hour.                                         Tier 3
                                                                inh QID
                   DuoNeb, Combivent                            Neb: 3mL inh     Neb: 6 doses Subcategory: COPD (Obstructive),         $6                                                    Neb:
                   Neb: 0.5mg/2.5mg/3mL                         QID              MDI: 12 puffs Other (Restrictive/Neoplastic)                                                                TMieDr I1: D
                   MDI: 18mcg/90mcg/spray                       MDI: 1-2 puffs                                                         MDI:                                                  Tier 3
                                                                inh QID                                                                $14.07
Lorazepam (CIV)    Ativan                                       0.5-2mg          10mg     Fear/anxiety-induced n/v Intermediate-       $2                                                    Tier 1
                   Tablet: 0.5, 1, 2mg                          Q4-6h                     acting benzodiazepine; may be given          $2                                                    Tier 1
Morphine (IR)      Solution, oral: 2mg/mL                                                 PO, SL, PR, SQ, IM; reduce dose if liver     $1                                                    Tier 1
(CII)              Solution, injection: 2mg, 4mg/mL             Q2h PRN          N/A      disease present
NaCl 0.9% sterile  MSIR, Roxanol                                3mL Q4h PRN 150meq        Dosage for SOB is 5-10mg Q2h PRN
for inhalation     Tablet: 15, 30mg                                                       SubQ: 5-15mg SubQ Q2-4h PRN
                   Solution, oral: 10mg/5mL, 20mg/5mL, 20mg/mL                            CrCl 10-50: decr. Dose 25%;
                   Solution, injection as sulfate: 15mg/mL                                CrCl <10: decr. Dose 50%
                   Bronchosaline                                                          Subcategory: COPD (Obstructive)
                   Neb: 0.9%                                                              Fluid intake is encouraged
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                                   $2.50 Tabs Tier 1
69Oxycodone (IR)   OxyIR, Oxydose,                  Dyspnea/Shortness of Breath (continued)
(CII) – (Morphine  Roxicodone
intolerant)        Tablet: 5, 15, 30mg              Dosed Q2hr N/A         Dosage for SOB is 5-10mg Q2h PRN; preferred for
Prednisone         Capsule: 5mg                     PRN                    patients with severe renal impairment
                   Deltasone
Bumetanide         Solution, oral: 1mg/mL           5-80mg        80mg     GI upset, use with caution in patients with diabetes    ¢                                                         Tier 1
                   Tablet: 1, 2.5, 5, 10, 20, 50mg  4x daily                                                                                                                                 Tier 1
                                                                                                                                                                                             Tier 1
                   Bumex                                          Edema                                                                                                                      Tier 1
                   Tablet: 0.5, 1, 2mg
                                                    0.5-10mg/day  10mg     Subcategory: Congestive Heart Failure , Abdominal       ¢
                                                    daily BID              Aortic Aneurysm (AAA), Severe Aortic Stenosis w/CHF     ¢
                                                                           Therapeutic Class: Diuretics (loop)                     $1
                                                    10-160mg               Monitor for hypokalemia; administer last dose
                                                    daily-BID              before 4pm
Furosemide         Lasix                            12.5-50mg     600mg    Subcategory: Congestive Heart Failure, Severe Aortic
                   Tablet: 20, 40, 80mg             daily                  Stenosis w/CHF, Abdominal Aortic Aneurysm (AAA)
                   Solution, oral: 10mg/mL,                                Therapeutic Class: Diuretics (loop)
                   40mg/5mL                                                Monitor for hypokalemia
                                                                           Anuria: contraindicated
Hydrochlorothiazide Microzide, Hydrodiuril                        200mg    Subcategory: Abdominal Aortic Aneurysm (AAA),
                                Tablet: 25, 50mg
                                Capsule: 12.5mg                            Severe Aortic Stenosis w/CHF, Congestive Heart Failure
                                                                           Therapeutic Class: Diuretics (thiazide)
                                                                           Anuria: contraindicated
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/DayTier
Metolazone                                                                                                                                                                                   $2        Tier 1
70              Zaroxolyn                                   Edema (continued)
                Tablet: 2.5, 5, 10mg                                                                                                                                                         $1        Tier 1
                                                2.5-20mg     20mg              Subcategory: Congestive Heart Failure,
                                                daily                          Abdominal Aortic Aneurysm (AAA), Severe
                                                                               Aortic Stenosis w/CHF
                                                                               Therapeutic Class: Diuretics (thiazide)
                                                                               Not a potent diuretic alone; used in conjunction
                                                                               with Lasix or Bumex; administer 30min prior to
                                                                               dose of Lasix or Bumex
Potassium       K-Dur, Klor-Con                 20meq        100meq            May cause diarrhea, nausea, vomiting or abdominal
Chloride        Capsule, XR: 8, 10meq           2-5x daily                     pain
                Tablet, ER: 8, 10, 15, 20meq
Spironolactone  Solution, oral: 20, 40meq/15mL  20-200mg     400mg             Subcategory: Congestive Heart Failure, Severe $1                                                                        Tier 1
                                                daily                          Aortic Stenosis w/CHF, Abdominal Aortic                                                                                 Tier 2
                Aldactone                                                      Aneurysm (AAA)
                Tablet: 25, 50, 100mg                                          Therapeutic Class: Diuretics (potassium
                                                                               sparing)
                                                                               Especially useful with ascites, prevents third spacing;
                                                                               may cause constipation and hypotension
                                                                               CrCl <10: contraindicated; anuria, acute renal
                                                                               impairment: contraindicated
Triamterene/    Maxzide, Dyazide                25mg/37.5mg  75/50mg           Triamterene is a potassium sparing diuretic        ¢
HCTZ            Tablet: 25/37.5, 50/75mg        daily
                Capsule: 25/37.5mg
Generic                                                                                                                                        ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Benztropine                                                                                                                          $1 Tier 1
Diphenhydramine71Cogentin                                Extrapyramidal Symptoms                                                     ¢ Tier 1
Acetaminophen    Tablet: 0.5, 1, 2mg
                                                         0.5-2mg BID 6mg            May cause sedation
Aspirin          Benadryl
Ibuprofen        Capsule/Tablet: 25, 50mg                            4mg (elderly)
                 Elixir: 12.5mg/5mL
                                                         25-100mg    400mg          Use with caution in elderly patients; causes
                 Tylenol                                 QHS and/or                 confusion/drowsiness dizziness; will not affect
                 Tablet: 325, 500mg                      Q4-6h PRN                  blood pressure
                 Tablet, chewable: 80, 160mg
                 Caplet/Geltab: 500mg                                Fever
                 Caplet/Geltab, extended release: 650mg
                 Liquid, oral: 500mg/15mL, 160mg/5mL     500-1000mg 4000mg          Max of 3000mg for elderly.                       ¢ - $3  Tier 1
                 Suppository: 120, 650mg                 Q4-6h                      Max of 2000mg for patients with hepatic
                                                                                    impairment.
                 Bayer, Ecotrin
                 Tablet: 81, 325, 500, 650mg             325-650mg 4000mg           Monitor for antiplatelet effects                 ¢ Tier 1
                 Supp: 300, 600mg                        Q4hr PRN                                                                    ¢ Tier 1
                                                                                    Take with food/milk; may cause GI
                 Motrin, Advil                           400-800mg 3200mg           upset; monitor concomitant use with
                 Tablet: 200mg [OTC], 400, 600, 800mg    Q6h                        cor ticosteroids
                 Capsule/Gelcap: 200mg [OTC]                                        Caution if cardiovascular dz, CHF, HTN
                 Suspension: 100mg/5mL
                 Drops, oral: 40mg/mL
                 Chewable: 50, 100mg
Generic                                                                                                                                        ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Naproxen
72                                        Fever (continued)
Aluminum/
Magnesium       Naprosyn                                           250-500mg 1500mg        250mg naproxen= 275mg   $1 Tier 1
Aluminum/       Tablet: 250, 375, 500mg                            BID                     naproxen sodium
Magnesium/      Suspension: 125mg/5mL                                                      CrCl <30: avoid use
Simethicone
                                          Gastrointestinal Irritation/Colic
Calcium
Carbonate       Gaviscon                                           5-10mL daily            Avoid use in end stage renal disease $1  Tier 1
                Aluminum hydroxide 8mg and magnesium trisilicate   PRN
Dicyclomine     20mg
                Mylanta, Maalox                                    15-30mL                 Avoid use in end stage renal disease $2  Tier 1
                Liquid: Aluminum hydroxide 200mg, magnesium        4x daily PRN
                hydroxide 200mg, and simethicone 20mg per 5mL
                (360mL); Aluminum hydroxide 400mg, magnesium
                hydroxide 400mg, and simethicone 40mg/5mL (360mL)
                Tablet, chewable: Aluminum hydroxide 200mg,
                magnesium hydroxide 200mg and simethicone 25mg
                Tums, Rolaids                                      1-2 Qday      7000mg    May cause constipation  ¢ Tier 1
                Tums: 500mg                                        PRN           (as an
                Tums E-X: 750mg                                                  antacid)
                Tums Ultra: 1000mg
                Bentyl                                             10-20mg       160mg     Anticholinergic; may cause urinary $1    Tier 1
                Tablet: 20mg                                       Q6-8h                   retention or blurry vision
                Capsule: 10mg
                Solution, oral: 10mg/5mL
Generic                                                                                                                                           ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/DayTier
Famotidine
Nizatidine73                           Gastrointestinal Irritation/Colic (continued)
Omeprazole
Ranitidine    Pepcid                                              20mg BID      40mg     CrCl <50: decr. dose 50% or give     $1 Tier 1
              Tablet: 10, 20, 40mg
Sucralfate    Suspension: 40mg/5mL                                              20mg (renal) Q36-48h
Lansoprazole
              Axid                                                150mg BID 300mg        CrCl 20-50: 150mg daily              6 Tier 1
              Capsule: 150, 300mg                                                        CrCl <20: 150mg Q48h
              Solution, oral: 15mg/mL
              Prilosec                                            20mg          360mg    OTC form is preferred; RX            $1 OTC:Tier 1
              Tablet and Capsule [OTC], delayed release: 20mg                            OMEPRAZOLE IS NON-                                   Rx:Tier 3
              Capsule, delayed release: 10, 20, 40mg              Daily to BID           FORMULARY - USE OTC.
                                                                                                                              $3 Tier 1
              Zantac                                              150mg         300mg    Well tolerated; may be crushed
              Tablet, as hydrochloride: 75mg [OTC], 150mg [OTC],  QHS or BID             CrCl <50: 150mg daily
              300mg                                               IM/IV:                 CrCl <10: 75-150mg daily
              Solution, oral: 15mg/mL                             50mg Q6-8h
              Capsule: 150mg, 300mg
              Solution, injection: 50mg/2mL
              Carafate                                            1g 4x daily 6g         Can be constipating; shake well;     $3 Tier 1
              Tablet: 1g                                                                 drug interaction with proton pump
              Suspension: 1g/10mL                                                        inhibitors and other antacids; Give
                                                                                         1h before meals, bedtime
              Prevacid, Prevacid SoluTab, Prevacid OTC            30mg PO       180mg    Reserve for patients unable to       OTC:      OTC:Tier 2
              Capsule, delayed release: 15, 30mg                  daily                  swallow or NPO                       $1-$2     Rx:Tier 3
              Suspension: 15mg/5mL (150mL, 300mL)                                                                             Rx: $5
              Tablet, ODT: 15, 30mg
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                           Gout
74Allopurinol        Zyloprim                        100-300mg                        CrCl 10-20: 200mg daily; CrCl 3-10: 100mg daily or                                                     ¢ - $1    Tier 3
Colchicine           Tablet: 100, 300mg              daily            800mg           300mg 2x/wk                                                                                            $6 - $12  Tier 3
                                                     0.6mg daily-BID
                     Colcrys                                          1.2mg           CrCl less than 30: 0.3mg/day
                     Tablet: 0.6mg                                                    Dialysis: 0.3mg BID
Baclofen             Lioresal                        5-15mg TID          Hiccups      May lower seizure threshold                                                                            $1 - $2 Tier 1
Chlorpromazine       Tablet: 10, 20mg                                 80mg
                     Thorazine
Metoclopramide       Tablet: 10, 25, 50, 100, 200mg  10-50mg          1000mg          May be given PO, SL, PR; more sedating; avoid in                                                       $4        Tier 1
                                                     Q4-6h                            patients with Parkinson’s disease                                                                      $1        Tier 1
                     Reglan                          5-10mg                           May cause orthostatic hypotension
                     Tablet: 5, 10mg                 4x daily                                                                                                                                $5        Tier 3
                     Solution, oral: 5mg/5mL                          60mg            Gastric stasis-induced n/v
                                                     BID              30mg (elderly)  Avoid in patients with Parkinson’s; monitor for EPS
                                                                                      and agitation; Decr. dose 50% in elderly pts; give
                                                                                      30min before meals.
                                                                                      CrCl 41-50: decr. dose 25%
                                                                                      CrCl 10-40: decr. dose 50%
                                                                      Hyperglycemia
Intermediate         Novolin 70/30,                                   Individualized
Acting Insulin       Humulin 70/30
                                                     Daily Individualized Basal Insulin                                                                                                      $5 Tier 3
Long Acting Insulin  Lantus
                                                     PRN              Individualized BGM divided by 3 minus 3 equals dose for coverage $5                                                              Tier 3
Short Acting         Novolin R, Humulin R
Insulin
Generic                                                                                                                                        ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Clonazepam
(CIV)75          Klonopin                                            Insomnia                                                         $2 Tier 1
                 Tablet: 0.5, 1, 2mg                                                                                                                 ODT:
Diphenhydramine  ODT wafer: 0.125, 0.25, 0.5, 1, 2mg   Anxiety: 1mg/day 4mg (anxiety) Long-acting benzodiazepine; should not be used                 Tier 3
Melatonin        Benadryl                              Seizure: 0.5mg 20mg         in combo with short-acting benzodiazepine          ¢ Tier 1
Mirtazepine      Capsule/Tablet: 25, 50mg
                 Elixir: 12.5mg/5mL                    TID and titrate (seizure)
Temazepam        Tablet: 1.3mg
(CIV)                                                  25-100mg      400mg         Use with caution in elderly patients; causes       ¢ Tier 1
Trazodone        Remeron, Remeron SolTab               QHS and/or    5mg           confusion/drowsiness/dizziness; will not affect
                 Tablet: 7.5, 15, 30, 45mg             Q4-6h PRN                   blood pressure
Triazolam (CIV)  SolTab (ODT): 15, 30, 45mg
Zolpidem (CIV)   Restoril                              0.3-5mg QHS                 3 to 4 hours before an imposed sleep period
                 Capsule: 7.5, 15, 22.5 (BRAND), 30mg                              over 4 weeks
                 Desyrel                               7.5-30mg      45mg                                                             $2-$3       Tab:Tier 1
                 Tablet: 50, 100, 150, 300mg           QHS                         Also expected to improve sleep and mood            Soltab: $5  SolTab:
                                                                                                                                                  Tier 3
                 Halcion                               15-30mg QHS 30mg            7.5mg capsule is NON- FORMULARY                    $1
                 Tablet: 0.125, 0.25mg                                                                                                            Tier 1
                 Ambien, Ambien CR
                 Tablet: 5, 10mg                       25-100mg QHS  400mg         Useful to treat insomnia                           ¢ - $1      Tier 1
                 Tablet, CR: 6.25, 12.5mg                            (depression)
                                                       0.125-0.25mg  200mg         Short-term use                                     $1          Tier 1
                                                       QHS           (insomnia)    Short half-life; wears off after approximately 5
                                                       5-10mg QHS    0.5mg         hours. 5mg PO QHS or 6.25mg ER PO QHS in           $3-$5       Tier 1
                                                                                   elderly or debilitated pts; give on empty stomach  CR: $5      CR:
                                                                     10mg                                                                         Tier 3
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
76                                                      Mucositis/Dry Mouth                                                                                                                  Generic forms are preferred             $1 Tier 1
                                                                                                                                                                                             Should swish for 30 sec prior to        $1 Tier 1
Artificial Saliva  Artificial Saliva, Salivart          Q1-3h PRN               none                                                                                                         spitting out
                                                                                                                                                                                                                                     $1 Tier 1
Chlorhexidine      Peridex                              15mL swish/spit BID 30mL                                                                                                             For viscous solution 1mL = 20mg of      $2 Tier 1
Rinse              Solution: 0.12%                                                                                                                                                           lidocaine
                                                        PRN                     none                                                                                                         Swish and spit out
Dry Mouth Rinse    Biotene                              0.225mL/kg Q3h PRN                                                                                                                   Not systemically absorbed
                                                                                15mL/dose                                                                                                    Use x48h after sx resolve
Lidocaine          Xylocaine                                                    8 doses
(Viscous)          Solution, viscous: 2%                                                                                                                                                     Can be constipating; shake well;
                                                                                                                                                                                             drug interaction with proton pump
Nystatin           Mycostatin                           500,000 - 1,000,000     2.4 million                                                                                                  inhibitors and other antacids; Give 1h  $3.50    Tier 1
                   Suspension: 100,000 units/mL         units 4x daily x 10-14  units                                                                                                        before meals, bedtime
                                                        days
Sucralfate         Carafate                             swish +/- swallow       6g                                                                                                           May lower seizure threshold             $3 Tier 1
                   Tablet: 1g
                   Suspension: 1g/10mL                  1g 4x daily                                                                                                                          Long-acting benzodiazepine; should
                                                                                                                                                                                             not be used in combo with short-
                                                                    Muscle Spasms                                                                                                            acting benzodiazepine
Baclofen           Lioresal                             5-15mg TID              80mg                                                                                                                                                 $1 - $2  Tier 1
                   Tablet: 10, 20mg                                                                                                                                                                                                  $2
Clonazepam                                              Anxiety: 1mg/day        4mg (anxiety)                                                                                                                                                 Tier 1
(CIV)              Klonopin                             Seizure: 0.5mg TID      20mg (seizure)                                                                                                                                                ODT:
                   Tablet: 0.5, 1, 2mg                  and titrate                                                                                                                                                                           Tier 3
                   ODT wafer: 0.125, 0.25, 0.5, 1, 2mg
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/DayTier
77                                                     Muscle Spasms (continued)
Cyclobenzaprine  Flexeril                              5mg daily 30mg         Avoid used in mod-severe hepatic      $1 -$4                                                                   Tier 1
Carisoprodol     Tablet: 5, 10mg                                              impairment
                 Soma                                  350mg TID 4x daily     May be sedating                       $2 (350mg) Tier 2
                 Tablet: 250 (BRAND), 350mg                                   Max x 2-3 weekly
                                                                                                                    $11                                                                      250mg:
                                                                                                                    (250mg)                                                                  Tier 3
                                                                                                                                                                                             (Formerly Tier 2)
Tizanidine       Zanaflex                              8mg     36mg           Max: 3 doses/24h; 12mg/dose           $3 TABS                                                                  Tier 2
                 Tablet: 2, 4mg                        Q6-8hr                 Give consistently w/ food or on       $7-$14                                                                   Tier 1
                 Capsule: 2, 4, 6mg                                           empty stomach                         CAPS                                                                     Tier 1
Diazepam (CIV)   Valium                                      Nausea/Vomiting  Fear/anxiety-induced n/v              $1
                 Tablet: 2, 5, 10mg
                 Solution, oral: 5mg/5mL, 5mg/mL       2-10mg                 May be given PO, SL, PR; long half-
                                                       Q6-12h
                                                                              life; use with caution in elderly w/
                                                                              liver disease; DIASTAT RECTAL GEL:
                                                                              NON-FORMULARY
Erythromycin     Ery-tab, E.E.S, EryPed                250-500mg 4000mg       Gastric stasis-induced n/v            $4 - $8
                 Suspension (BRAND): 200, 400mg/5mL    BID 4x daily           Useful in pulmonary infections;
                 Tablet, DR: 250, 333 (BRAND),                                causes GI upset and diarrhea
                 500mg (BRAND)                                                Give IR on empty stomach
                 Tablet, as base/stearate: 250, 500mg
                 Capsule, as base/stearate: 250mg
                 Tablet, as ethylsuccinate: 400mg
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                                                                                             $1 Tier 1
78                                                   Nausea/Vomiting (continued)
                                                                                                                                                                                             $4 Tier 1
Haloperidol  Haldol                                  0.5-5mg Q6-12h  100mg            Drug of choice for opioid-induced n/v
             Tablet:0.5, 1, 2, 5, 10, 20mg                                            Can be given PO, SL, PR, IM                                                                            $2 Tier 1
             Solution as lactate, oral: 2mg/mL                                        Useful when benzodiazepines fail                                                                       $3 - $5 Tier 1
             Solution, injection as lactate: 5mg/mL                                   Do not use in patients with Parkinson’s                                                                $1 Tier 1
                                                                                      Low sedation
Hyoscyamine  Levsin, Levbid                          0.125-0.25mg    1.5mg            Movement-induced n/v
             Solution, oral: 0.125mg/5mL             Q4-6h                            May cause blurred vision, dry mouth, dry eyes
             Oral drops: 0.125mg/mL
             Tablet: 0.125, 0.15
             Tablet, ER: 0.375mg
             ODT: 0.125mg
Lorazepam    Ativan                                  0.125-0.25mg    10mg             Fear/anxiety-induced n/v-Cerebral Cortex
(CIV)        Tablet: 0.5, 1, 2mg                     Q4-6h                            Intermediate-acting benzodiazepine; may be
             Solution, oral: 2mg/mL                                                   given PO, SL, PR, SQ, IM; reduce dose if liver
             Solution, injection: 2mg, 4mg/mL                                         disease present
Meclizine    Antivert, Bonine, Dramamine             12.5-50mg                        Movement-induced n/v
             Tablet: 12.5, 25, 50mg                  Q8-12h                           Anticholinergic; may cause dizziness or
             Tablet, chewable: 25mg                                                   drowsiness
Metoclopramide Reglan                                5-10mg          60mg             Gastric stasis-induced n/v
                          Tablet: 5, 10mg            4x daily        30 mg (elderly)  Avoid in patients with Parkinson’s; monitor for
                          Solution, oral: 5mg/5mL                                     EPS and agitation; Decr. dose 50% in elderly pts;
                                                                                      give 30min before meals.
                                                                                      CrCl 41-50: decr. dose 25%
                                                                                      CrCl 10-40: decr. dose 50%
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/DayTier
Prochlorperazine                                                                                                          $3 - $9   Tier 1
79                 Compazine                     Nausea/Vomiting (continued)
                   Tablet: 5, 10mg
                   Suppository, rectal: 25mg     5-10mg PO or     150mg    Constant/intermittent/unknown cause n/v
                                                 25mg PR Q4-8h             Do not use in patients with Parkinson’s
                                                                           Less sedating than promethazine
Promethazine       Phenergan                     12.5-25mg Q4-6h  150mg    Preferred in patients with Parkinson’s         $2 - $14 Tier 1
                   Tablet: 12.5, 25, 50mg                         32mg     Use with caution in the Elderly
Ondansetron        Solution, oral: 6.25mg/5mL    4-8mg Q8hr                More sedating than Prochlorperazine
                   Suppository, rectal: 25mg                      20mg
Trimethobenzamide                                250-300mg        8mg      Only indicated for chemotherapy indu-          $3-$4     Tier 2
Dronabinol         Zofran, Zofran ODT            Q6-8hr PRN                ced nausea/vomiting                            ODT:
Glycopyrrolate     Tablet: 4, 8, 16, 24mg        2.5mg BID                                                                $39-$65   ODT:
                   ODT: 4, 8mg                   1-2mg Q4-12h              Child-Pugh Class C: max 8mg/24h                          Tier 3
                   Solution, oral: 4mg/5mL
                   Solution, injection: 4mg/2mL                            Can be given IV, IM
                   Tigan                                                   CrCl <70: consider decr. dose amt or freq                Tier 2
                   Tablet: 250, 300mg
                                                                           Also indicated as AIDs-related appetite stimulant $12 - $25 Tier 3
                   Marinol
                   Capsule: 2.5, 5, 10mg                                   Movement-induced n/v                           $5 - $8   Tier 3
                                                                           Reserve for patients who develop confusion on            Tier 3
                   Robinul                                                 anticholinergic therapy                        $3 (per
                   Tablet: 1, 2mg                                                                                         tablet)
                                                                           Only indicated for chemotherapy indu-
Granisetron        Kytril                        2mg Q6-8hr                ced nausea/vomiting
                   Tablet: 1mg                                             Not preferred
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                                           $4 Tier 3
80                                                                   Nausea/Vomiting (continued)
Scopolamine    Transderm Scop                                        1 patch TD  3 patches  May cause blurred vision/confusion; titrate
Patch          1.5mg patch (releases 1mg over 72 hours)              Q3d                    difficult; do not use if phlegm or mucus is
                                                                                            present; may cause mucus plug
                                                                     Pain - Nociceptive (Mild)
Acetaminophen  Tylenol                                               500-1000mg 4000mg      Max of 3000mg for elderly                      ¢ - $3  Tier 1
               Tablet: 325, 500mg                                    Q4-6h                  Max of 2000mg for patients with hepatic
               Tablet, chewable: 80, 160mg                                                  impairment
               Caplet/Geltab: 500mg
               Caplet/Geltab, extended release: 650mg
               Liquid, oral: 500mg/15mL, 160mg/5mL
               Suppository: 120, 650mg
Aspirin        Bayer, Ecotrin                                        325-650mg 4000mg       Monitor for antiplatelet effects               ¢ Tier 1
               Tablet: 81, 325, 500, 650mg                           Q4hr PRN
               Supp: 300, 600mg                                      2-16mg BID 40mg        GI upset, use with caution for patients with
                                                                                            diabetes due to resultant hyperglycemia. Give
Dexamethasone Decadron                                               400-800mg 3200mg       last dose by 2pm to avoid steroid-induced      ¢ - $2  Tier 1
                         Solution, oral: 1mg/mL                      Q6h                    insomnia. May be given SubQ, IM, IV
                         Tablet: 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6mg
                                                                                            Take with food/milk; may cause GI upset;
Ibuprofen      Motrin, Advil                                                                monitor concomitant use with corticosteroids   ¢ Tier 1
               Tablet: 200mg [OTC], 400, 600, 800mg                                         Caution if cardiovascular dz, CHF, HTN
               Capsule/Gelcap: 200mg [OTC]
               Suspension: 100mg/5mL
               Drops, oral: 40mg/mL
               Chewable: 50, 100mg
Generic                                                                                                                                        ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Indomethacin                                                                                                                                                                                 $2 Tier 1
81              Indocin                          Pain - Nociceptive (Mild) continued
Meloxicam       Capsule: 25, 50mg                                                                                                                                                            $3 - $5 Tier 1
                Capsule, ER: 75mg                25mg            200mg    Only NSAID that can cross blood                                                                                    $1 Tier 1
Naproxen        Suppository, rectal: 50mg        Q8-12hr                  brain barrier                                                                                                      ¢ Tier 1
                Suspension (BRAND): 25mg/5mL                                                                                                                                                 $5 Tier 2
Prednisone      Mobic                            7.5-15mg daily  15mg     COX-1 and -2 mixed inhibitor
                Tablet: 7.5, 15mg                                         CrCl <15: avoid use                                                                                                $6 - $15 Tier 3
Choline         Suspension: 7.5mg/5mL            250-500mg BID 1500mg
Magnesium       Naprosyn                                                  250mg naproxen= 275mg naproxen
Trisalicylate   Tablet: 250, 375, 500mg          5-80mg 4x daily 80mg     sodium.
Celecoxib       Suspension: 125mg/5mL                                     CrCl <30: avoid use
                Deltasone                        1000mg Q12h     4500mg
                Solution, oral: 1mg/mL                                    GI upset, use with caution in patients
                Tablet: 1, 2.5, 5, 10, 20, 50mg  100-200mg daily 800mg    with diabetes
                Trilisate
                Solution, oral: 500mg/5mL                                 Do not use in salicylate or aspirin
                                                                          allergy; may cause tinnitus; less GI
                Celebrex                                                  effects.
                Capsule: 50, 100, 200, 400mg                              Advanced CRI: contraindicated
                                                                          Caution with sulfa allergy and for
                                                                          patients who have experienced a
                                                                          recent GI bleed.
                                                                          Severe renal impairment: avoid use
Generic                                                                                                                                         ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                                             $2 Tier 1
Hydrocodone/82   Vicodin, Lortab, Norco                    Pain - Nociceptive (Moderate)
Acetaminophen    Tablet: various, most common: 5mg/500mg,
(CIII)           7.5mg/750mg, 10mg/660mg                   1-2 tabs Q4-6h 4000mg of              Monitor total acetaminophen intake
                 Elixir: 7.5mg/500mg/15mL
Oxycodone/                                                            acetamin.
Acetaminophen    Percocet,Tylox
(CII)            Tablet: various, most common: 5mg/325mg,             3000mg (elderly)
                 5mg/500mg, 10 mg/325mg
Tramadol (IR)    Solution: Roxicet® 5mg/325mg/5mL          1-2 tabs Q4-6h 4000mg of              Monitor total acetaminophen intake          $2 - $4 Tier 1
Acetaminophen/   Ultram                                               acetamin.
Codeine (CIII)   Tablet: 50, 100mg
Tramadol/        Tablet, ER: 100, 200, 300mg                          3000mg (elderly)
Acetaminophen
                 Tylenol #3                                50mg 4x daily 400mg                   May lower seizure threshold                 $4       Tier 1
Methadone (CII)  Tablet: 300mg/30mg                                             300mg (elderly)  CrCl <30: give Q12h, max 200mg/day                   ER Form:
                                                                                                 Cirrhosis: 50mg Q12h, max 100mg/day         $4 - $6  Tier 3
                 Ultracet                                  1-2 tabs   12 tabs                    Weak opioid; may be effective for           $2 - $7  Tier 2
                 Tablet: 37.5-325mg                        Q4-6h PRN                             diarrhea
                                                                                                 Treatment should not exceed 5 days                   Tier 2
                 Dolophine                                 2 tabs Q4-6h 8 tabs
                 Solution, oral: 5, 10mg/5mL, 10mg/mL      PRN pain                              Excellent for nociceptive and
                 Tablet: 5, 10mg                                                                 neuropathic pain and for patients with
                                                           Pain - Nociceptive (Severe)           renal or hepatic impairment; call clinical
                                                                                                 pharmacist for dosage
                                                           Individualized N/A                                                                ¢ Tier 1
Generic                                                                                                                                         ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/DayTier
                                                                                                                                                                                             Tier 1
Morphine (IR)83                                            Pain - Nociceptive (Severe) continued                                                                                             Tier 1
(CII)                                                                                                                                                                                        Tier 1
                   MSIR, Roxanol                                      Q2h PRN        N/A             Dosage for SOB is 5-10mg Q2h PRN $2                                                     Tier 2
Morphine ER/SR     Tablet: 15, 30mg                                                                  SubQ: 5-15mg SubQ Q2-4h PRN                                                             Tier 2
Tablet (CII)       Solution, oral: 10mg/5mL, 20mg/5mL, 20mg/mL                                       CrCl 10-50: decr. Dose 25%;                                                             Tier 3
                                                                                                     CrCl <10: decr. Dose 50%
Oxycodone (IR)
(CII)              MS Contin, Oramorph SR                             Dosed Q12h N/A                 DO NOT CRUSH; may be given $1 - $10
                   Tablet, ER, SR: 15, 30, 60, 100, 200mg                                            rectally: CrCl 10-50: decr. dose 25%;
Hydromorphone                                                                                        CrCl <10: decr. dose 50%
(CII)
                   OxyIR, Oxydose, Roxicodone                         Dosed Q2hr N/A                 Dosage for SOB is 5-10mg Q2h        $2.50 Tabs
Oxycodone          Tablet: 5, 15, 30mg                                PRN                            PRN; preferred for patients with
Solution (IR)      Capsule: 5mg                                                                      severe renal impairment
(CII) - (Morphine  Solution, oral: 20mg/mL                            Dosed Q4-6h N/A
Intolerant)                                                                                          Option for patients on high dose    $5
Fentanyl (CII)     Dilaudid                                           Dosed Q2hr N/A                 morphine and not able to use
                   Solution, oral (BRAND): 1mg/mL                     PRN                            methadone
                   Suppository, rectal: 3mg
                   Tablet: 2, 4, 8mg                                                                 Dosage for SOB is 5-10mg Q2h        $10 - $40
                                                                                                     PRN; preferred for patients with    Liquid
                   Oxyfast                                                                           severe renal impairment
                   Solution, oral: 20mg/mL
                   Duragesic Patch, Actiq, Fentora                    Patch changed  Opioid naïve    Adequate fat tissue required to     $6-$15
                   Transdermal Patch: 12.5mcg/h, 25mcg/h; 50mcg/h,    Q72h           25mcg           absorb medication from patch;       PATCH
                   75mcg/h, 100mcg/h                                                 Lozenge: 2      difficult to titrate; do NOT cut    $33-$98
                   Transmucosal Lozenge (BRAND): 200, 400, 800,                      doses/episode;  patches.                            LOZENGE
                   1200, 1600mcg                                                     4 doses/day     Solution, injectable: Liquid given  $52-$151
                   Buccal tablet (BRAND): 100, 200, 400, 600, 800mcg                                 ORALLY for ESRD patients only.      BUCCAL
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDose Max/DayCommentsCost/Day Tier
                                                                                                                                                                                             $10 - $33 Tier 3
84Morphine SR                                          Pain - Nociceptive (Severe) continued
Capsule (CII)
               Avinza                                  Dosed Q24h N/A            Avoid in patients with severe renal or hepatic
                                                                                 impairment; do NOT crush; may administer per peg
               Capsule, ER (BRAND): 30, 60, 90, 120mg                            tube or sprinkle on soft food
Oxycodone SR   Oxycontin                               Dosed        N/A          DO NOT CRUSH; non-preferred                                                                                 $5 - $28  Tier 3
(CII)                                                                                                                                                                                                  Tier 1
Carbamazepine  Tablet, ER/CR: 10, 15, 20, 30, 40, 60, 80mg Q12hr                                                                                                                                       Tier 1
                                                                                                                                                                                                       Tier 1
Desipramine                                 Pain - Neuropathic (Shooting, Stabbing, Burning,Tingling)
Divalproex                                                                                                                                                                                             Tier 1
Sodium         Tegretol                                100-400mg 1600mg          Subcategory: Brain cancer                                                                                   $1 - $2
               Tablet, chewable: 100mg                 BID 4x daily              Can be given rectally                                                                                       $1
Gabapentin     Tablet, ER: 100, 200, 400mg                                       DO NOT CRUSH ER tablets                                                                                     $2
               Suspension, oral: 100mg/5mL                                       Give with food. CrCl <10: decr. dose 25%
                                                                                                                                                                                             $1 - $3
               Norpramin                               10-150mg     300mg        Also expected to improve sleep and mood; least
               Tablet: 10, 25, 50, 75, 100, 150mg      QHS                       anticholinergic effect; max in elderly is 150mg per day
               Depakote, Depakote Sprinkles            15mg/kg/day  60mg/kg/day  Give with food; may open and sprinkle capsules
               Tablet, DR: 125, 250, 500mg                                       on food. Divalproex sodium ER and DR tabs not
               Tablet, ER: 250, 500mg                                            bioequivalent; incr. total daily dose by 8-20% if
               Capsule, DR: 125mg                                                switching from DR tab to ER tab.
                                                                                 Hepatic dz/significant impairment: contraindicated
               Neurontin                               100mg TID    3600mg       Must titrate up and down; may cause memory loss;
               Capsule: 100, 300, 400mg                and titrate               very sedating
               Solution, oral: 250mg/ 5mL              Q72h                      CrCl 30-60: 200-700 mg BID; CrCl 16-29: 200-
               Tablet: 600, 800mg                                                700mg daily; CrCl 15: 100-300 mg daily; CrCl <15:
                                                                                 decr. Dose proportionately to CrCl
Generic                                                                                                                                           ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                                         ¢ Tier 1
Methadone85    Dolophine                                Pain - Neuropathic (continued)
(CII)          Solution, oral: 5, 10mg/5mL, 10mg/mL
               Tablet: 5, 10mg                          Individualized N/A          Excellent for nociceptive and neuropathic pain and
                                                                                    for patients with renal or hepatic impairment; call
                                                                                    clinical pharmacist for dosage
Nortriptyline  Pamelor                                  10-150mg       150mg        Also expected to improve sleep and mood; start at $1                                                     Tier 1
Valproic Acid  Capsule: 10, 25, 50, 75mg                QHS                         lowest dose possible                                                                                     Tier 1
               Solution, oral: 10mg/5mL
                                                        250mg          60mg/kg/day  Drug levels required for seizures only; DO NOT       $3                                                  Tier 2
               Depakene                                 QHS x 7 days,  300mg        CRUSH ER FORMS; Depakene may be given rectally                                                           Tier 2
               Syrup, as valproic acid: 250mg/5mL       Then 500mg     120mg                                                             ¢ - $1                                              Tier 3
               Capsule, as valproic acid: 250mg         QHS                         Also expected to improve sleep and mood; increases   $6                                                  Tier 3
                                                        10-150mg       3 patches    risk of falls                                        Variable
Amitriptyline  Elavil                                   QHS                         Useful to treat neuropathic pain                     $16
Duloxetine     Tablet: 10, 25, 50, 75, 100, 125, 150mg  60mg daily                  Do not cut/crush/chew/sprinkle
                                                                                    CrCl <30: avoid use
               Cymbalta                                 Consult with                Can be given PO/IV;Used for sedation/nerve pain
               Capsule, DR (BRAND): 20, 30, 60mg        ProCare
                                                        Pharmacist                  May cut patches
Ketamine       Ketalar                                  1 patch up
               Solution for Injection;                  to 12 hrs/day
Lidocaine      10mg/mL, 50mg/mL, 100mg/mL
Patch
               Lidoderm Patch
               5% patch
Generic                                                                                                                                        ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                        Pruritis
Chlorpheniramine86Chlor-Trimeton                              4mg Q6hr             24mg     Take with full glass of water           ¢      Tier 1
Cholestyramine    Tablet: 4mg                                                      24g
                  Questran                                    4g 1-4x daily                 Dissolved in juice or water; promotes $1 - $2  Tier 1
Colloidal         Powder, pkt: 4g cholestyramine/9g powder                         400mg    formed stools; useful in C. diff
Oatmeal/          Powder, scoop: 4g cholestyramine/9g powder  Apply PRN            300mg
Mineral Oil       Aveeno                                                                    Very good for itchy dry skin; some      $8 (8 packet) Tier 1
Diphenhydramine                                               25-100mg             600mg    formulations also contain menthol
                  Benadryl                                    QHS and/or
Doxepin           Capsule/Tablet: 25, 50mg                    Q4-6h PRN                     Use with caution in elderly patients;   ¢      Tier 1
                  Elixir: 12.5mg/5mL                          10-30mg QHS                   causes confusion/drowsiness/dizziness;  $1     Tier 1
Hydrocortisone    Sinequan                                                                  will not affect blood pressure
Hydroxyzine       Capsule: 10, 25, 50, 75, 100, 150mg         1-2% applied
                  Solution, oral: 10mg/mL                     Topically BID                 Caution in elderly; OK if bedbound;
Menthol/Camphor   Cortaid, Cortisone                          10-50mg                       causes drowsiness
Lotion            Cream: 1%, 2%                               Q4-6h
                  Atarax,Vistaril                                                           Useful if rash present; do not use on   $5 (28 gram) Tier 1
                  Capsule as pamoate:25, 50, 100mg            Apply topically PRN           open areas                              $3 Tier 1
                  Tablet, HCl: 10, 25, 50mg
                  Solution, oral: 10mg/5mL                                                  May cause drowsiness; use with
                  Sarna Lotion, Gold Bond Medicated                                         caution in the elderly; useful in
                  Lotion                                                                    patients with Parkinson’s
                                                                                            OTC; offers a soothing, cooling effect $11 (222mL) Tier 1
Generic                                                                                                                                          ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Paroxetine                                                                                                                                                                                   $2 Tier 1
87             Paxil                                              Pruritis (continued)
Diazepam       Tablet: 10, 20, 30, 40mg                                                                                                                                                      $1 Tier 1
(CIV)          Tablet, ER: 12.5, 25, 37.5mg         10-40mg           50mg               Mechanism for cough unknown; effective for                                                          $2 Tier 1
Lorazepam      Suspension: 10mg/5mL                 daily             40mg (elderly,     cough after 1-3 doses
(CIV)                                                                 renal/hepatic)                                                                                                         $1 - $2 Tier 1
               Valium
Carbamazepine  Tablet: 2, 5, 10mg                   2-10mg        Seizure - Active       May be given PO, SL, PR; long half-life; use with                                                   $2 Tier 1
               Solution, oral: 5mg/5mL, 5mg/mL      Q6-12h             10mg              caution in elderly w/ liver disease; DIASTAT                                                                       ODT:
Clonazepam     Ativan                                                                    RECTAL GEL: NON-FORMULARY                                                                                          Tier 3
(CIV)          Tablet: 0.5, 1, 2mg                  0.5-2mg
Diazepam       Solution, oral: 2mg/mL               Q4-6h                                Intermediate-acting benzodiazepine; may be                                                          $1 Tier 1
(CIV)          Solution, injection: 2mg, 4mg/mL                                          given PO, SL, PR, SQ, IM; reduce dose if liver
                                                                                         disease present
               Tegretol
               Tablet, chewable: 100mg                            Seizure - Maintenance
               Tablet, ER: 100, 200, 400mg
               Suspension, oral: 100mg/5mL          100-400mg         1600mg             Subcategory: Brain cancer
               Klonopin                             BID 4x daily                         Can be given rectally
               Tablet: 0.5, 1, 2mg                                                       DO NOT CRUSH ER tablets
               ODT wafer: 0.125, 0.25, 0.5, 1, 2mg                                       Give with food. CrCl <10: decr. dose 25%
               Valium
               Tablet: 2, 5, 10mg                   Anxiety: 1mg/day  4mg (anxiety) Long-acting benzodiazepine; should not be used
               Solution, oral: 5mg/5mL, 5mg/mL      Seizure: 0.5mg    20mg (seizure) in combo with short-acting benzodiazepine
                                                    TID and titrate
                                                    2-10mg                               May be given PO, SL, PR; long half-life; use with
                                                    Q6-12h                               caution in elderly w/ liver disease; DIASTAT
                                                                                         RECTAL GEL: NON-FORMULARY
Generic                                                                                                                                           ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
Divalproex                                                                                                                                                                                   $2 Tier 1
Sodium88       Depakote, Depakote Sprinkles               Seizure - Maintenance (continued)
               Tablet, DR: 125, 250, 500mg                                                                                                                                                   $2 Tier 1
Lorazepam      Tablet, ER: 250, 500mg                     15mg/kg/day     60mg/kg/day  Give with food; may open and sprinkle capsules                                                        $1 Tier 1
(CIV)          Capsule, DR: 125mg                                                      on food. Divalproex sodium ER and DR tabs not                                                         $1 Tier 1
                                                                                       bioequivalent; incr. total daily dose by 8-20% if
Phenobarbital  Ativan                                                                  switching from DR tab to ER tab.                                                                      $3 Tier 1
(CIII)         Tablet: 0.5, 1, 2mg                                                     Hepatic dz/significant impairment: contraindicated
Phenytoin      Solution, oral: 2mg/mL
               Solution, injection: 2mg, 4mg/mL           0.5-2mg         10mg         Intermediate-acting benzodiazepine; may be given
Valproic Acid  Luminal                                    Q4-6h                        PO, SL, PR, SQ, IM;
               Tablet: 15, 16, 30, 32, 60, 65, 97, 100mg                               reduce dose if liver disease present
               Elixir: 20mg/5mL
               Dilantin, Phenytek                         60-100 mg       400mg dose   May be given PO, PR, IM; long half-life allows less
               Capsule, ER: 100, 200, 300mg               daily BID-TID   60mg/kg/day  frequent dosing
               Tablet, chewable (BRAND): 50mg             300mg daily                  CrCl <10: give Q12-16h
               Suspension: 25mg/mL
                                                          250mg QHS x 7                Subcategory: Brain cancer
               Depakene                                   days,                        Long half-life allows for once daily dosing;
               Syrup, as valproic acid: 250 mg/5mL        then 500mg QHS               Poor absorption when given rectally;
               Capsule, as valproic acid: 250mg                                        Oral suspension binds to tube feeds;
                                                                                       Reduce dose in patients with hypoalbuminemia
                                                                                       ER Capsule: Do not open/crush/chew
                                                                                       Drug levels required for seizures only;
                                                                                       DO NOT CRUSH ER FORMS;
                                                                                       Depakene may be given rectally
ProCare HospiceCare Preferred Drug ListGenericBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                                 $2 - $3 Tier 1
89                                                     Terminal Secretions                                                       $4 Tier 1
Atropine 1%  Isopto Atropine                           1-3gtts SL                 May cause anticholinergic delirium if used
             Opth soln: 5, 15mL                        Q4-6h PRN                  too early; not to be used if phlegm or mucus
                                                                                  present as may cause mucus plug
Hyoscyamine  Levsin, Levbid                            0.125-0.25mg    1.5mg      May cause blurred vision, dry mouth, dry eyes
             Solution, oral: 0.125mg/5mL               Q4-6h
             Oral drops: 0.125mg/mL
             Tablet: 0.125, 0.15
             Tablet, ER: 0.375mg
             ODT: 0.125mg
Glycopyrrolate Robinul                                 1-2mg Q4-12h    8mg        Reserve for patients who develop confusion     $5 - $8  Tier 3
                       Tablet: 1, 2mg                                             on anticholinergic therapy                     $4       Tier 3
Scopolamine  Transderm Scop                            1 patch TD Q3d  3 patches  May cause blurred vision/ confusion; titrate
Patch                                                                             difficult; do not use if phlegm or mucus is
             1.5mg patch (releases 1mg over 72 hours)                             present; may cause mucus plug
                                                             INFECTIONS / ANTIBIOTICS
             PO Antibiotics covered for infections related to the terminal diagnosis (for symptom management)
                                                                IV / IM Antibiotics - Tier 3
Amoxicillin  Trimox, Amoxil                            250-500mg TID   4000mg     Useful in pulmonary, sinus, and urinary tract  $2 - $3 Tier 1
             Capsule: 250, 500mg                                       2000mg     infections. May be given with or without food
             Suspension: 125, 200, 250, 400mg/5mL                      (renal)    CrCl 10-30: give Q12h;
             Tablet: 500, 875mg                                                   CrCl <10: give Q24h
             Tablet, chewable: 125, 200, 250, 400mg                               Do not use 875mg tab if CrCl <30
Generic                                                                                                                                               ProCare HospiceCare Preferred Drug ListBrand/Available FormDoseMax/DayCommentsCost/Day Tier
                                                                                                                               $1 Tier 1
90                                              Infections / Antibiotics (continued)
Azithromycin   Zithromax                        500mg day 1,     2000mg        Useful in pulmonary infections Severe renal
               Tablet: 250, 500, 600mg          then 250mg                     impairment: caution advised
Bacitracin     Suspension: 100, 200mg/5mL       daily x 4 days
Cefaclor       1g pwdr pkt
                                                Apply topically  5 x day; 7    Useful in optic and pulmonary infections;       $3/30g                                                        Tier 1
Cefuroxime     Baciguent                        BID-TID          day duration  May be given with or without food               $4 - $7                                                       Tier 1
Cephalexin     Ointment: 500 units/g
                                                250-500mg        2000mg
Ciprofloxacin  Ceclor                           daily x 7 days
               Capsule: 250, 500mg
               Tablet, ER: 375, 500mg           250-500mg                      Useful for optic and pulmonary infections       $4                                                            Tier 1
               Suspension: 125, 250, 375mg/5mL  BID x 5-10 day                                                                                                                               Tier 1
                                                                               Useful in skin and pulmonary infections May be  $43                                                           Tier 1
               Ceftin                           1000-4000mg/day 4000mg         given with or without food                      $2
               Tablet: 250, 500mg               Divided Q6-Q12h                CrCl 50-90: give Q6-8h; CrCl 10-50: give
               Suspension: 125, 250mg/5mL                                      Q8-12h; CrCl<10: give Q12-24h
                                                250-750mg
               Keflex                           Q12h x 5-10 days               Useful in urinary tract infections
               Capsule: 250, 500mg                                             IR Form: CrCl 30-50: 250-500mg Q12h;
               Suspension: 125, 250mg/5mL                                      CrCl 5-29:
               Tablet: 250mg, 500mg                                            250-500mg Q18h; CrCl <5: not defined
                                                                               ER Form: CrCl <30: 500mg Q24h
               Cipro
               Tablet: 100, 250, 500, 750mg
               Tablet, ER: 500, 1000mg
               Suspension: 250, 500mg/5mL