COVID-19 mRNA Vaccine Excipients - PEG
Release date：2021/4/23 9:37:17
The COVID-19 pandemic has infected millions of people, but there is no obvious sign of
relief due to the high infection rate, long incubation period and lack of mature treatments
or vaccines. Vaccines are the most promising solution for mitigating new virus strains.
In the past year, the COVID-19 vaccine has developed rapidly. Dozens of candidate
vaccines are being tested in clinical trials to evaluate their safety and effectiveness.
Currently, there are 14 COVID-19 vaccines on the global market.
Type Company Brand Name Approval
1 Pfizer–BioNTech BNT162b2/Tozinameran/ Comirnaty 83
Adenovirus vector Countries
2 Moderna mRNA-1273 46
Inactivated virus Countries
3 Gamaleya Research Institute of Sputnik V/Gam-COVID-Vac 62
Protein subunit Epidemiology and Microbiology Countries
4 Oxford–AstraZeneca AZD1222/Vaxzevria 91
5 Janssen (Johnson & Johnson) Ad26.COV2.S/Ad26COVS1/JNJ-78436735 40
6 CanSino Biologics Convidecia/Ad5-nCoV 5 countries
7 Serum Institute of India Covishield 33
8 Sinopharm(Beijing) BBIBP-CorV 35
9 Sinovac Biotech CoronaVac 22
10 Bharat Biotech/Indian Council Covaxin/BBV152 6
of Medical Research Countries
11 Sinopharm(Wuhan) WIBP-CorV 2
12 Chumakov Centre CoviVac 1 Country
13 Vector Institute EpiVacCorona 2
14 Anhui Zhifei Longcom/ Institute RBD-Dimer/ZF2001 2
of Microbiology Countries
Find more COVID-19 vaccine info: https://covid19.trackvaccines.org/
Currently, the mRNA vaccine is the most widely administered vaccine in the world.
Previously, there had been no commercial mRNA vaccine, and it had not been tested in
large human trials and had not been clinically proven. And COVID-19 changed all that.
Now, let's discovered the ingredients of Pfizer's vaccine and Moderna's vaccine.
As mentioned in the above table, both the Pfizer and Moderna vaccines
contain polyethylene glycol (PEG). According to the MIT, PEGs are basically tiny, greasy
spheres that are used in COVID vaccines to protect the active ingredient (mRNA) and
help it penetrate cells. It is within cells that the mRNA can go to work priming the immune
Biochempeg can produce and provide the following PEG products that can use
in COVID-19 vaccines.
1 mPEG-N,N-Ditetradecylaceta CAS No.
2 mPEG-DMG CAS NO.
3 mPEG-CH2CH2CH2-NH2 ---
4 mPEG-OH CAS NO.:
5 mPEG-CM (mPEG-AA) ---