SKI 25 Programme Book

SKI-XXV “CHEMISTRY AND BEYOND: EXPLORING NEW OPPORTUNITIES 3rd MARCH 2022

OPPORTUNITIES”

P21

MICROPLASTIC IDENTIFICATION USING FT-IR

A. R. Zuhari1, M. R. A. Manapp1*, N. Hazfalinda2
1Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
2 Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 43600 UKM Bangi,

Selangor, Malaysia.
*Corresponding author: [email protected]

Each year, the microplastics industry grows. Increased use of microplastics, increases the
risk of pollution, particularly in areas where water is present, such as the sea and the beach.
The key challenge in this work is obtaining microplastic, which is significantly smaller than
regular plastic. The goal of this research was to find a microplastic polymer that could be
discovered in Tioman Island. Microplastic sampling was carried out at the high tide line of
the sea or beach, as plastic that floats and gathers at the high tide line. Forceps were used
to collect samples, which were then placed in a vial with a unique lot number. The Sample
Inventory Management System was used to store all the sample information. The samples
will be pretreated with hydrogen peroxide H2O2 once they arrive at the laboratory. The goal
of this procedure is to eliminate organic material from the sample to improve the quality of
the spectra during analysis. The Fourier Transform Infrared Spectrometer (FTIR) was used
to analyse the samples, and the samples had to be fully dry before the examination. Spectra
were saved in Opus format, and each spectrum was analysed using three separates
programmes: IR Analyzer, KnowItAll, and Opus. The polymers identified from the sample are
polyethylene, polyvinyl chloride, polypropylene, polystyrene, and nylon. The polymer peaks
that were discovered in the sample were all recorded. Some of the samples will be identified
using Opus, but with different parameters, after they have been identified using three
separate tools.

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P22

DESIGN, IN SILICO STUDIES AND SYNTHESIS OF HYDROXYLATED N-METHYL-4-
PIPERIDONE CURCUMIN ANALOGS AS ANTIBACTERIAL AGENTS

S. N. M. Zahar1, S. M. M. Faudzi1,2*
1Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
2Natural Medicines and Product Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia,

43400 Serdang, Selangor, Malaysia.
*Corresponding author: [email protected]

Skin infections caused by bacteria are a worldwide problem in which all age groups can be infected,
both normal and immunocompromised patients. Some of the most common bacteria that cause
skin infections are Staphylococcus, Pseudomonas and Propionibacterium genera and affected
patients have been commonly treated with antibiotics. However, the increase of antibiotic resistance
in pathogenic bacteria has become one of the major threats to global health. Therefore, further
research to discover and develop new antibacterial drugs with fewer side effects and higher efficacy
is still needed. Previously, piperidinyl-based chalcone derivatives have shown significant
antibacterial properties against skin infections. Following that, a new series of hydroxylated N-
methyl-4-piperidone diarylpentanoids, a curcumin derivative, were designed, evaluated for their
binding affinity and interaction with the active site in an in-silico study, and synthesized to validate
the in-silico results. Based on the molecular docking results, compound 3,5-dibenzylidene-1-
methylpiperidin-4-one (1a) and 3,5-bis(3,5-dimethoxybenzylidene)-1-methylpiperidin-4-one (1i)
were found to have similar chemical interactions to the standard drug sialic acid in the binding cavity
of the protein JNK1 with binding affinities of -8.6 and -9.1 kcal/mol respectively. Subsequently, the
predicted active 1a and 1i were synthesized by base-catalyzed Aldol condensation. The
compounds were then structural characterized by 1H nuclear magnetic resonance (1H-NMR) and it
was found that the compound still consisted of mixtures. Successive recrystallization and column
chromatography were performed for purification but did not result in a pure compound. Therefore,
the in vitro antibacterial assay to evaluate the targeted efficacy could not be performed.

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P23

IN-VITRO PENETRATION STUDY OF NANOEMULSION CONTAINING ESSENTIAL OIL
DERIVED FROM BACKHOUSIA CITRIODORA

N. S. Shahidan1, N. Salim1,2*
1Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
2Centre of Foundation Studies for Agricultural Science, Universiti Putra Malaysia, 43000 UPM Serdang,

Selangor, Malaysia.
*Corresponding author: [email protected]

Nanoemulsions have been proven to be resourceful and efficient novel active ingredients
delivery systems as it shows excellent bioavailability and have great stability for droplet
aggregation and creaming. Backhousia citriodora, commonly known as lemon myrtle, is a
plant from the Myrtaceae family and Backhousia genus. This lemon myrtle plant main
constituents are citral (3,7-dimethyl-2-7-octadienal) and two primary isomeric aldehydes,
neral and geranial. Many studies have shown that lemon myrtle exhibit strong germicidal and
antifungal activity indicating its potential as an antiseptic. However, there is no in vitro
penetration study of nanoemulsion containing essential oil derived from backhousia
citriodora in different pH of receptor media that has yet to be conducted. Therefore, this
project aims to study the in vitro release of nanoemulsion containing LMEO in different pH
receptor media through in vitro techniques. The Franz diffusion cell experiment was carried
out in triplicates, and the samples were collected at different time intervals for 90 min at
different pH (pH 5.5 and pH 7.4) and then the samples were analysed by UV-Vis
spectroscopy. From the results, after 90 min, pH 5.5 recorded the highest absorbance,
0.0103 at 296.3 nm, meanwhile, pH 7.4 recorded the highest absorbance, 0.0057 at
wavelength 293.8 nm. The highest absorbance for pH 5.5 was higher than the highest
absorbance for pH 7.4. Hence, it can be concluded that lowering the pH will cause the
increasement in the absorbance value. From this study, it is recommended to construct
calibration curve to analyse the concentration of the released LMEO nanoemulsion.

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P24

DETERMINATION OF FATTY ACID TYPES OF THERMOPHILIC CYANOBACTERIA USING
LIQUID CHROMATOGRAPHY MASS SPECTROMETER (LC/MS) AND GEL PERMEABLE

CHROMATOGRAPHY (GPC)

F. L. Yee1, A. N. Steven1*
1Department of Chemistry, Faculty of Science, University Teknologi Malaysia, 81310 Johor Bahru,

Malaysia
*Corresponding author: [email protected]

Thermophilic cyanobacteria, as photoautotrophic organisms, possess the metabolism to transform
climate-damaging carbon dioxide (CO2) to biomass with light as energy source and they are
growing optimally in extreme environment. This ability makes them to promising green cell factories
for a more sustainable production of useful molecules. In this study, strains of thermophilic
cyanobacteria were cultivated in BG11 medium at the optimal temperature of 45°C, under
continuous illumination with light-emitting diodes (LED) lamp for 1~2 weeks. The product produced
by thermophilic cyanobacteria such as fatty acid and polyhydroxyalkanoates (PHA) were used for
sustainable product development. For enhancing the production of fatty acid and PHA in
cyanobacteria, nutrition starvation and nutrient supplement were done based on biosynthetic
pathway. The biomass of cultured cells was harvested by centrifugation. The total lipids were
manually extracted following the method of Bligh and Dyer. The determination of fatty acids
composition was performed using liquid chromatography mass spectrometer (LC-MS) and the
molecular weight distribution of PHA was determined using gel permeable chromatography (GPC).
From this research work, it revealed that the total amount of fatty acids in cultured cyanobacteria
increased with decrease in nitrogen and phosphorous concentration in the growth medium. The
significance of this research study has discovered the potentially new strains of thermophilic
cyanobacteria that are able to produce the most suitable fatty acids to use in wastewater treatment
and the PHA compound produced are biodegradable, readily to be used by plastics industry for
sustainability production commercially.

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P25

INVESTIGATION OF WATER TREATMENT: CDI TECHNOLOGY USING CARBON-
BASED ELECTRODE MATERIALS AND INTERCALATION ELECTRODE MATERIALS

M. H. H. Ismail1, L. H. Ngee1,2*
1Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
2Functional Device Laboratory, Institute of Advanced Technology, Universiti Putra Malaysia,

43400 UPM Serdang, Selangor, Malaysia
*Corresponding author: [email protected]

Nowadays, freshwater demand has been increasing drastically due to the fast growth of the
population and industries worldwide. To meet the demand, more water purification methods have
been created. However, the conventional technology suffers from higher cost, low removal
efficiency, and high energy consumption. Researchers are interested in capacitive deionization
(CDI) because of its economic friendly, low energy consumption, high ions removal, and
environmental friendliness. Theoretically, a pair of electrodes, anode and cathode, will be used to
adsorb ions from the electrolyte into their surface. In a few years, CDI has been going through rapid
transformation on their system architecture, electrode compositions, and their capability in many
application fields. Electrode materials have become a big influence on overall desalination
performance. Because of their minimal price, large specific surface area, and outstanding electrical
conductance, carbon composites have been used as electrodes in CDI. The ions will be absorbed
and stored in the electrode double layer (EDL) that created between solution and interface of the
electrode with opposite charges. However, it has problem with the low desalination capacity.
Recently, intercalation materials that have an exceptional ions removal has taken a place to be a
main electrode material in CDI process. The mechanism of ions adsorption in intercalation materials
starts when ions will adsorb and insert into the lattice structure site on the intercalation host
compound due to the redox reaction. These materials have been proved to have higher salt
adsorption capacity (SAC) from the carbon-based electrode.

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SKI-XXV “CHEMISTRY AND BEYOND: EXPLORING NEW OPPORTUNITIES 3rd MARCH 2022
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P26

DESIGN AND DEVELOPMENT OF NEW JACAREUBIN DERIVATIVES AS ANTI-
CANCER AGENT

N. M. Nasir1*, P. Devakrishnan1, N. A. H. Hadi1, N. Q. A. A. Nordin1
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia
*Corresponding author: [email protected]

Jacareubin can be categorised as prenylated xanthone as it can be obtained from heartwood of
the American tropical tree Calophyllum brasiliense. Jacareubin exhibits antibacterial and
gastroprotective properties and the intention for clinical use as an anti-cancer treatment (due to
the similar chemical structure to other anti-neoplastic drugs). Therefore, synthetic approach has
been carried out to explore other possible patterns of jacareubin derivatives with various
substituent due to its limited availability and diversity in nature. In this project, seven jacareubin
derivatives were successfully synthesised and characterised with nitro substituent, amino
substituent and fluoro substituent. Column chromatography was being used to purify the product
and characterisation of their structures was done using FTIR, NMR and GC-MS spectroscopic
analysis. The first part of the synthesis is to give xanthone product through Eaton’s Reagent
method before undergoes cyclization to form jacareubin derivative. The use of Eaton’s reagent as
a catalyst will condense reaction between the starting materials; phloroglucinol and
aminosalicyclic acid that potentially gives higher yield compared to the classical method. The
cyclization steps with prenal and Ca(OH)2 in dry methanol, MeOH will then lead to formation of
jacareubin.

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P27

TURN-OFF FLUORESCENCE SENSOR BASED ON CARBON DOTS FOR GLUCOSE
DETERMINATION

N. Harun1, J. Abdullah1*
1Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
*Corresponding author: [email protected]

In this study, L-phenylalanine functionalized carbon dots (CDs-L-Ph) for the determination of
glucose has been explored. The CDs-L-Ph was synthesised using carbonized palm kernel shell
and L-phenylalanine as precursor by one step hydrothermal method. The CDs-L-Ph was
characterised by High Resolution Transmission Electron Microscopy (HRTEM) and Fourier
Transform Infrared Spectroscopy (FTIR), and the optical properties were studied by UltraViolet-
Visible Spectroscopy (UV-vis) and Spectrofluorometer. It is found that the CDs-L-Ph exhibit
uniform spherical shape and slightly monodispersed with an average size of 2.30 ± 0.06 nm. FTIR
has proved the functionalized CDs-L-Ph. The evaluation for determination of glucose via turn off
fluorescence method of CDs-L-Ph has been achieved. The developed sensor demonstrated good
linearity for glucose determination in the concentration range of 0.1 to 0.5 mM with limit of
detection (LOD) of 0.07 mM.

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SKI-XXV “CHEMISTRY AND BEYOND: EXPLORING NEW OPPORTUNITIES 3rd MARCH 2022
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P28

ADJUSTED GAFF PARAMETERS THAT REPRODUCE ACCURATE STATIC DIELECTRIC
CONSTANT AND DENSITY

M. F. Ismail1*, W. A. F. C. Hussin1
1Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
*Corresponding author: [email protected]

General AMBER Force Field is compatible with AMBER force fields. It is included with all the
parameters for all organic molecules. The parameters including bond stretch, angle bending,
torsional and improper dihedral in bonded parameters and also Lennard-Jones and Coulombic
interaction in the non-bonded parameters. The default basis set that is used in generating partial
charges is HF/6-31G* which is one of the lowest methods in ab initio calculation to optimize the
value of electrostatic charges. But, all the default parameters lead to inaccurate static dielectric
constant and density. In this study, the main concern is about the accuracy and in producing the
static dielectric constant and density of the solvent molecules from the original GAFF parameters.
To achieve that, the parameter that compute electrostatic interaction need to be modified and
using uniform scale to produce more accurate static dielectric constant and density. The two
values which are static dielectric constant and density are closely related to each other as stated
in the formula of the static dielectric constant. With GAFF, the value of dielectric constant and
density from the molecular simulation are deviating too much from the experimental value. After
a uniform scaling factor is introduced, the error is minimized and the value is very close to the
experimental value. To be exact, the error can be as low as 0.1% which is obtained for diethyl
ether dielectric constant and 0.29% for its density. There are no error greater than 3% if compared
the simulation with the experimental.

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SKI-XXV “CHEMISTRY AND BEYOND: EXPLORING NEW OPPORTUNITIES 3rd MARCH 2022

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P29

IN SILICO STUDY OF CAROTENOID AND PHENOLIC COMPOUNDS FROM CHLORELLA

SP. MICROALGAE AGAINST BETA-AMYLOID FIBRIL USING MOLECULAR DOCKING AND

MOLECULAR DYNAMICS SIMULATIONS

N. J. Bella1, N. H. Faujan2*
1Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia
2Centre of Foundation Studies for Agricultural Science, Universiti Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia
*Corresponding author: [email protected]

Alzheimer's disease (AD) is one of neurodegenerative disorder characterized by the formation of
Amyloid-beta (Aβ) plaques in brain cells. Several epidemiological studies have demonstrated that
antioxidant compounds reduce the risk of AD. This project focused on the potential of carotenoid
and phenolic compounds from Chlorella sp. as an antioxidant agent against Amyloid-beta fibril
(PDB ID: 2NAO) using in silico study. The best binding affinity and binding interactions of
carotenoids and phenolic compounds with Aβ42 fibril were determined using molecular docking.
Molecular dynamics (MD) simulations were focused on fucoxanthin (FCX) and 4-hydroxyl benzoic
acid (HYD) compounds as the potential carotenoid and phenolic compounds to inhibit Aβ42 fibril
conformation. Root mean square displacement (RMSD) analysis showed Aβ42-4-hydroxyl benzoic
acid (Aβ42-HYD) complex was more stable compared to Aβ42-fucoxanthin (Aβ42-FCX) complex.
Root mean square fluctuation (RMSF) and radius of gyration (Rg) analyses showed both FCX and
HYD compounds inhibited the conformation of Aβ42 fibril and Aβ42 fibril was less compact in the
presence of the FCX compound. Solvent accessible surface area (SASA) of Aβ42-FCX complex
was higher than Aβ42-HYD complex indicating that Aβ42-FCX complex contains a higher surface
area of Aβ42 fibril that expose to water with more hydrophobic interactions formed. The simulation
results showed that fucoxanthin could bind to Aβ42 fibril better than 4-hydroxyl benzoic acid which
would be used as a potential drug to treat AD. This study provides theoretical insights into the
inhibitory mechanism of antioxidant compounds against Aβ42 peptide which is beneficial for AD
drug design.

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P30

ADSORPTION OF METHYLENE BLUE AND PARACETAMOL BY CARBON NANOTUBE

N. E. N. Hilmy1, N. Ayob1, A. H. Abdullah1*
1Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
*Corresponding author: [email protected]

Carbon nanotube is tubular nanocrystalline carbon clusters constructed from rolled graphene
sheets and capped at the ends by fullerene caps. Carbon atoms are arranged in a series of fused
benzene rings that are pleated into cylindrical shape to form carbon nanotube (CNT). Carbon
nanotubes have a large surface area, which allows them to have greater adsorption capabilities
and unique electrical characteristic. The unique properties of CNT make CNT widely used in many
applications such as catalyst support, chemical sensor, hydrogen storage and water treatment. In
this study, the efficiency of carbon nanotube was evaluated as the promising adsorbent to remove
paracetamol and methylene blue (MB). The effect of different parameters including initial
concentration and adsorbent dosage were observed. The experimental data was fitted to Langmuir
and Freundlich isotherm to study the adsorption mechanism. The increase of initial concentration
of MB and paracetamol results in lower percentage removal. While, increase in adsorbent dosage
increased the removal efficiency of MB and paracetamol. Maximum adsorption capacity for MB
and paracetamol onto CNT are 42.02 mg/g and 11.22 mg/g, respectively. The best condition for
removal of MB (99.4%) was achieved at 10 mg/L MB and 0.3 g CNT. While, 47.17% at 15 mg/L
paracetamol and 0.5 g CNT. The adsorption of both MB and paracetamol onto CNT follows
Langmuir isotherm and pseudo second-order kinetic models. Therefore, CNT effectively remove
MB and paracetamol from aqueous solution.

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P31

SYNTHESIS OF BROMINATED BENZIMIDAZOLE

N. N. N. Azlan1, N. S. M. Rafi1, E. A. Malek1*
1Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia
*Corresponding author: [email protected]

Since benzimidazole derivatives are prominent biologically active compounds, they are often
synthesized for medicinal applications. However, the structure-related features of such
heteroaromatic molecular structures have many applications, particularly in the optical sensor. The
benzimidazole unit's multifunctionality, which includes electron-accepting, -bridging, chromogenic
pH sensor, and metal-ion chelating characteristics, makes it an excellent structural option for
optical chemical sensors and functional materials. As a result, the research of molecular sensors
has become a popular trend, in which benzimidazole units play an important role. Thus, due to this
trend, benzimidazole was synthesised, which will be employed in the last step of developing an
optical sensor. The benzimidazole was synthesised via a condensation reaction between o-
phenylenediamine and aldehyde. This reaction involved refluxing method, which was commonly
known as the conventional heating method. Then, this method was followed by a bromination
reaction between benzimidazole and N-bromosuccinimide (NBS). Brominated benzimidazole was
characterised using Nuclear Magnetic Resonance (NMR) to aid in determining the correct location
of H based on the chemical structure proposed. Brominated benzimidazole should have less H
since one H was substituted by Br. However, both results revealed that all H were present in the
structures that were corresponded to 2-phenyl-1H-benzimidazole and 2-(4-
nitrophenyl)benzimidazole. In conclusion, both benzimidazole derivatives can be synthesised by
different aldehyde using condensation reactions. Furthermore, benzimidazole derivatives were
synthesised via the green method using glycerol and NBS as a greener solvent and safe source of
bromine, respectively.

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P32

SYNTHESIS OF IONIC LIQUID TEMPLATED MESOPOROUS SILICA NANOPARTICLES
(MSNs) AND AMINE FUNCTIONALIZED MSNs FOR CO2 CAPTURE

N.A.A.M. Razali1, M. Z. Adnan1, H. Ahmad1*
1Department of Chemistry Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
* Corresponding author: [email protected]

Recently, the mesoporous silica nanoparticles (MSNs) have been investigated as the CO2
adsorbent due to the characteristics of the MSNs that have stable and large pores. In addition,
MSNs used as CO2 adsorbent have a low adsorption rate, however, due to the properties of the
MSNs that can be improved by modification of surface area, easy functionalization, and tunable
pores. hence, the adsorption rate will improve. Therefore, in this study, MSNs have been
synthesized using the pyridinium ionic liquid as the template because pyridinium ionic liquid has
a lower cost and toxicity, high thermal stability and biodegradable compared to other ionic liquid
based such as imidazolium ionic liquid. The MSNs was synthesized by adding tetraethyl
orthosilicate as silica precursor and addition of triethanolamine as base catalyst. After all, the
MSNs had been functionalized using the 3-aminopropyltriethoxysilane that have high density of
amine group. The functionalized of amine was synthesized using post-grafting methods and the
functionalized amine MSN was obtained in the white powder form. Fourier transform infrared
spectroscopy (FTIR), x-ray diffractometer (XRD), transmission electron microscopy (TEM) and
Brunauer-Emmett-Teller was used to determine the pore size, surface area and the properties of
the amine functionalized MSNs that can potentially be used for CO2 adsorption. From the
characterization, the functionalized amine MSN shows that it is have large pores and high surface
area that can be proposed for high adsorption of the CO2.

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P33

PREPARATION OF GO/TIO2 NANOCOMPOSITE AS A PHOTOCATALYST FOR
WASTEWATER MITIGATION

E. D. H. Kong1, C. S. Khe1*
1Department of Fundamental and Applied Sciences, Universiti Teknologi PETRONAS (UTP),

Perak, Malaysia
*Corresponding author: [email protected]

Various conventional methods like physical methods and biological methods which are cost
ineffective, time consuming had been employed to remove aromatic pollutants like dye and
petroleum hydrocarbon in wastewater. Still, these solutions are not able to efficiently remove
pollutants. Novel approaches for removal of these aromatic pollutants from wastewater is important
step in order to meet the increasing demands and the reduced supply of clean water due to
improper treatment of wastewater before releasing into water bodies. GO/TiO2 nanocomposite was
synthesized using modified Hummers’ method followed by drying after sonication and stirring of
GO/TiO2 solution. The synthesized nanocomposite was then used to study its performance in
simultaneously degrading aromatic hydrocarbons like methylene blue dye and crude oil. The
current study showed that the 10GT sample with the highest GO content exhibited the best
photocatalytic performance of 49% of MB dye and 41.37% crude oil degraded under 2 hours.
Samples after addition of GO all shown higher adsorption and photodegradation efficiency. For
future works, other operational parameters can be investigated in order to identify the most
effective conditions for the photocatalyst to work under as well as replacing ultraviolet light with
visible light which makes up about 40% of sunlight, as the irradiation source.

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P34

TOTAL PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF LEMON MYRTLE LEAVES
EXTRACT AND ITS FRACTIONS

S. N. Hamdan1, N. K. Kassim1*, S. N. L. Darimi1, N. A. M. Shahrul1
Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang,

Selangor, Malaysia.
*Corresponding author: [email protected]

Lemon myrtle (Backhousia Citriodora) is a species originated under the family of Myrtaceae. It has
been used traditionally to cure various types of diseases such as fever, muscle cramps, diabetes
mellitus and cancer. To date, very limited studies on Malaysia lemon myrtle were reported.
Therefore, the purpose of this study is to investigate the potential of Malaysia lemon myrtle as free
radical scavenger and their phytochemical constituents. The bioassay technique based on 1,1-
diphenyl-2-picrylhydrazyl (DPPH) radical assay and total phenolic content (TPC) were used to
identify the presence of antioxidant compounds in ethyl acetate extracts of Malaysia lemon myrtle
and its fractions. The result of DPPH assay showed that crude extract possessed very strong
scavenging activity indicates by IC50 value of 23.56 µg/ml while the highest fraction was LM 6 which
exhibited stronger scavenging activity amongst other fractions with IC50 value of 27.26 µg/ml.
Based on the TPC screened, the highest phenolic content was found in crude extract with the value
of 84.88 µg GAE/g extract followed by LM 6 with the value of 75.50 µg GAE/g extract. The
identification of bioactive compounds was analyzed using Gas Chromatography-Mass
Spectrometry technique. The total of six bioactive compounds were found in crude extract in which
two of them expected to found in LM 6 due to its polarity. The result of this study indicated highly
polar fractions possess stronger scavenging activity. Thus, lemon myrtle can serve as crucial
sources for development of effective medicinal product.

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ACKNOWLEDGEMENTS

We would like to thank all the companies who contributed generously for SKI-XXV.
This event is brought to you by

Megna Scientific

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NOTES

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SKI-XXV “CHEMISTRY AND BEYOND: EXPLORING NEW OPPORTUNITIES 3rd MARCH 2022

OPPORTUNITIES”

PHOTO GALERY

SKI-XXV ORGANISING COMMITTEE

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SKI-XXV “CHEMISTRY AND BEYOND: EXPLORING NEW OPPORTUNITIES 3rd MARCH 2022
OPPORTUNITIES”

THANK YOU FOR JOINING SKI XXV.
SEE YOU ALL NEXT YEAR

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