PCBs during pregnancy on ADHD symptoms and cognitive functions in Norwegian preschool children. Environment International 2016 Sep;94:649–60. 32. Caspersen IH, Haugen M, Schjølberg S, Vejrup K, Knutsen HK, Brantsæter AL, Meltzer HM, Alexander J, Magnus P, Kvalem HE. Maternal dietary exposure to dioxins and polychlorinated biphenyls (PCBs) is associated with language delay in 3 year old Norwegian children. Environment International 2016 May;91:180–7. 33. Hites RA, Foran JA, Carpenter DO, Hamilton MC, Knuth BA, Schwager SJ. Global assessment of organic contaminants in farmed salmon. Science 2004 Jan 9;303(5655): 226–9. 34. Seierstad SL, Seljieflot I, Johansen O, Hansen R, Haugen M, Rosenlund G, Frøyland L, Arnesen H. Dietary intake of differently fed salmon: the influence on markers of human atherosclerosis. European Journal of Clinical Investigation 2005 Jan;35(1):52–9. 35. Foran JA, Good DH, Carpenter DO, Hamilton MC, Knuth BA, Schwager SJ. Quantitative analysis of the benefits and risks of consuming farmed and wild salmon. Journal of Nutrition 2005 Nov;135(11): 2639–43. 36. National Resources Defense Council. The Smart Seafood Buying Guide. August 25, 2015, https://www.nrdc.org/stories/smart-seafood-buying-guide. 37. Fernando WM, Martins IJ, Goozee KG, Brennan CS, Jayasena V, Martins RN. The role of dietary coconut for the prevention and treatment of Alzheimer’s disease: potential mechanisms of action. British Journal of Nutrition 2015 Jul 14;114(1):1–14. 38. Jin JS, Touyama M, Hisada T, Benno Y. Effects of green tea consumption on human fecal microbiota with special reference to Bifidobacterium species. Microbiology and Immunology 2012 Nov;56(11):729–39. 39. Walker AW, Ince J, Duncan SH et al. Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME Journal 2011 Feb;5(2): 220–30. 40. Thompson T. Gluten contamination of commercial oat products in the United States. New England Journal of Medicine 2004 Nov 4;351(19):2021–2. 41. Sharma GM, Pereira M, Williams KM. Gluten detection in foods available in the United States—a market survey. Food Chemistry 2015 Feb 15;169:120–6. [Epub 2014 Aug 5.] 42. Bellioni-Businco B, Paganelli R, Lucenti P, Giampietro PG, Perborn H, Businco L. Allergenicity of goat’s milk in children with cow’s milk allergy. Journal of Allergy and Clinical Immunology 1999 Jun;103(6):1191–4. 43. Jenkins J, Breiteneder H, Mills EN. Evolutionary distance from human homologs reflects allergenicity of animal food proteins. Journal of Allergy and Clinical Immunology 2007 Dec;120(6):1399–405. 44. Restani P, Gaiaschi A, Plebani A, Beretta B, Cavagni G, Fiocchi A, Poiesi C, Velonà T, Ugazio AG, Galli CL. Cross-reactivity between milk proteins from different animal species. Clinical and Experimental Allergy 1999 Jul;29(7):997–1004. 45. Suutari TJ, Valkonen KH, Karttunen TJ, Ehn BM, Ekstrand B, Bengtsson U, Virtanen V, Nieminen M, Kokkonen J. IgE cross reactivity between reindeer and bovine milk beta-lactoglobulins in cow’s milk allergic patients. Journal of Investigational Allergology and Clinical Immunology 2006;16(5):296–302. 46. Iacono G, Carroccio A, Cavataio F, Montalto G, Soresi M, Balsamo V. Use of ass’ milk in multiple food allergy. Journal of Pediatric Gastroenterology and Nutrition 1992 Feb;14(2):177–81. 47. Vojdani A, Vojdani C. Immune reactivities against gums. Alternative Therapies in Health and Medicine 2015;21 Suppl 1:64–72. 48. Moneret-Vautrin DA, Morisset M, Flabbee J, Beaudouin E, Kanny G. Epidemiology of lifethreatening and lethal anaphylaxis: a review. Allergy 2005 Apr;60(4):443–51. 49. Finkel AV, Yerry JA, Mann JD. Dietary considerations in migraine management: does a consistent diet improve migraine? Current Pain and Headache Reports 2013 Nov;17(11): 373. doi: 10.1007/s11916-013-0373-4.
50. Popkin BM, Hawkes C. The sweetening of the global diet, particularly beverages: patterns, trends, and policy responses. Lancet Diabetes and Endocrinology 2016 Feb;4(2): 174–86. 51. USDA. Profiling Food Consumption in America, http://www.usda.gov/factbook/chapter2.pdf. 52. Singh A, Lal UR, Mukhtar HM, Singh PS, Shah G, Dhawan RK. Phytochemical profile of sugarcane and its potential health aspects. Pharmacognosy Reviews 2015 Jan–Jun;9(17):45–54. 53. Bokulich NA, Blaser MJ. A bitter aftertaste: unintended effects of artificial sweeteners on the gut microbiome. Cell Metabolism 2014 Nov 4;20(5):701–3. 54. James J, Thomas P, Cavan D, Kerr D. Preventing childhood obesity by reducing consumption of carbonated drinks: cluster randomised controlled trial. BMJ 2004 May 22;328(7450): 1237. doi: 10.1136/bmj.38077.458438.EE. 55. Purohit V, Bode JC, Bode C et al. Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium. Alcohol 2008 Aug;42(5):349–61. 56. The Harvard Mahoney Neuroscience Institute Newsletter, 2017, Sugar and the Brain, On the Brain, http://neuro.hms.harvard.edu/harvard-mahoney-neuroscience-institute/brain-newsletter/andbrain-series/sugar-and-brain, accessed 2017 Oct 12. 57. Kaushik M, Reddy P, Sharma R, Udameshi P, Mehra N, Marwaha A. The effect of coconut oil pulling on Streptococcus mutans count in saliva in comparison with chlorhexidine mouthwash. Journal of Contemporary Dental Practice 2016 Jan 1;17(1):38–41. 58. Ogbolu DO, Oni AA, Daini OA, Oloko AP. In vitro antimicrobial properties of coconut oil on Candida species in Ibadan, Nigeria. Journal of Medicinal Food 2007 Jun;10(2):384–7. 59. Bieschke J, Russ J, Friedrich RP, Ehrnhoefer DE, Wobst H, Neugebauer K, Wanker EE. EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity. Proceedings of the National Academy of Sciences of the United States of America 2010 Apr 27;107(17):7710–5. 60. Ehrnhoefer DE, Bieschke J, Boeddrich A, Herbst M, Masino L, Lurz R, Engemann S, Pastore A, Wanker EE. EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nature Structural & Molecular Biology 2008 Jun;15(6):558–66. 61. Grelle G, Otto A, Lorenz M, Frank RF, Wanker EE, Bieschke J. Black tea theaflavins inhibit formation of toxic amyloid-beta and alpha-synuclein fibrils. Biochemistry 2011 Dec 13;50(49):10624–36. 62. Bastianetto S, Yao ZX, Papadopoulos V, Quirion R. Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. European Journal of Neuroscience 2006 Jan;23(1):55–64. 63. Panossian A. Understanding adaptogenic activity: specificity of the pharmacological action of adaptogens and other phytochemicals. Annals of the New York Academy of Sciences 2017 Aug;1401(1):49–64. Epub 2017 Jun 22. 64. Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, Limpeanchob N, Norman Scholfield C. Metaanalysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. Journal of Ethnopharmacology 2014;151(1):528–35. 65. Calabrese C. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. Journal of Alternative and Complementary Medicine 2008 Jul;14(6):707–13. doi: 10.1089/acm.2008.0018. 66. Hota SK, Barhwal K, Baitharu I, Prasad D, Singh SB, Ilavazhagan G. Bacopa monniera leaf extract ameliorates hypobaric hypoxia induced spatial memory impairment. Neurobiology of Disease 2009 Apr;34(1):23–39. 67. Zhou Y, Qu ZQ, Zeng YS, Lin YK, Li Y, Chung P, Wong R, Hägg U. Neuroprotective effect of preadministration with Ganoderma lucidum spore on rat hippocampus. Experimental and Toxicologic Pathology 2012 Nov;64(7–8):673–80. 68. Choudhary D, Bhattacharyya S, Bose S. Efficacy and safety of ashwagandha (Withania somnifera (L.) Dunal) root extract in improving memory and cognitive functions. Journal of Dietary Supplements 2017 Nov 2;14(6):599–612.
69. Manchanda S, Kaur G. Withania somnifera leaf alleviates cognitive dysfunction by enhancing hippocampal plasticity in high fat diet induced obesity model. BMC Complementary and Alternative Medicine 2017 Mar 3;17(1):136. 70. Jamshidi N, Cohen MM. The clinical efficacy and safety of tulsi in humans: a systematic review of the literature. Evidence-Based Complementary and Alternative Medicine 2017; 2017:9217567. 71. Gohil KJ, Patel JA, Gajjar AK. Pharmacological review on Centella asiatica: a potential herbal cure-all. Indian Journal of Pharmaceutical Sciences 2010 Sep;72(5):546–56. 72. Heo HJ, Kim DO, Choi SJ, Shin DH, Lee CY. Potent inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid-beta-protein-induced neurotoxicity. Journal of Agricultural and Food Chemistry 2004 Jun 30; 52(13):4128–32. 10: THE FIX YOUR BRAIN RECIPES 1. https://www.ncbi.nlm.nih.gov/pubmed/21110905. 2. Ibid. 3. https://www.ncbi.nlm.nih.gov/pubmed/23748211. 4. https://academic.oup.com/nutritionreviews/article-abstract/72/9/605/1860232. 5. https://www.ncbi.nlm.nih.gov/pubmed/19685255. 6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782876/. 7. https://www.ncbi.nlm.nih.gov/pubmed/29263222. 8. https://academic.oup.com/jn/article/136/3/810S/4664377. 9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071963/. 10. https://www.ncbi.nlm.nih.gov/pubmed/28098514. 11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1702408/. 12. https://www.ncbi.nlm.nih.gov/pubmed/15534434. 13. https://www.sciencedirect.com/science/article/pii/S0278691509005912?via%3Dihub. 14. https://www.hindawi.com/journals/ecam/2013/946298/. 15. https://link.springer.com/chapter/10.1007/978-3-319-28383-8_12. 16. Ibid. 17. https://www.ncbi.nlm.nih.gov/pubmed/?term=honey+brain+health+benefits. 18. http://onlinelibrary.wiley.com/doi/10.1111/j1541-4337.2008.00047.x/full. 19. https://www.sciencedirect.com/science/article/pii/S0273230003001004. 20. https://www.ncbi.nlm.nih.gov/pubmed/26092628. 21. https://www.ncbi.nlm.nih.gov/pubmed/20443063. 22. https://pdfs.semanticscholar.org/1044/1b1f37d7329ad57eed745fcd91fe14b76fae.pdf. 23. https://www.ncbi.nlm.nih.gov/pubmed/29263222. 24. http://onlinelibrary.wiley.com/doi/10.1111/1750-3841.12434/full. 25. https://www.ncbi.nlm.nih.gov/pubmed/29263222. 26. https://www.ncbi.nlm.nih.gov/pubmed/19685255. 27. https://benthamopen.com/contents/pdf/TOOBESJ/TOOBESJ-2-101.pdf. 28. https://pdfs.semanticscholar.org/1044/1b1f37d7329ad57eed745fcd91fe14b76fae.pdf. 29. https://www.ncbi.nlm.nih.gov/pubmed/25553449. 30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375225/. 31. https://www.hindawi.com/journals/ecam/2012/193496/abs/. 11: LIVING WITH ELECTROMAGNETIC POLLUTION 1. Morris ZS, Wooding S, Grant J. The answer is 17 years, what is the question: understanding time
lags in translational research. Journal of the Royal Society of Medicine 2011 Dec;104(12):510–20. 2. Wertheimer N, Leeper E. Electrical wiring configurations and childhood cancer. American Journal of Epidemiology 1979 Mar;109(3):273–84. 3. Wertheimer N, Leeper E. Adult cancer related to electrical wires near the home. International Journal of Epidemiology 1982 Dec;11(4):345–55. 4. Vena JE, Graham S, Hellmann R, Swanson M, Brasure J. Use of electric blankets and risk of postmenopausal breast cancer. American Journal of Epidemiology 1991 Jul 15;134(2):180–5. 5. Gundestrup M, Storm HH. Radiation-induced acute myeloid leukemia and other cancers in commercial jet cockpit crew: a population-based cohort study. Lancet 1999 Dec 11;354(9195):2029–31. 6. Djordjevic NZ, Paunović MG, Peulić AS. Anxiety-like behavioural effects of extremely lowfrequency electromagnetic field in rats. Environmental Science and Pollution Research International 2017 Sep;24(27):21693–9. 7. Sage C, Burgio E. Electromagnetic fields, pulsed radiofrequency radiation, and epigenetics: how wireless technologies may affect childhood development. Child Development 2017 May 15. [Epub ahead of print.] 8. Belyaev I, Dean A, Eger H et al. EUROPAEM EMF Guideline 2016 for the prevention, diagnosis and treatment of EMF-related health problems and illnesses. Reviews on Environmental Health 2016 Sep 1;31(3):363–97. 9. Schoeni A, Roser K, Bürgi A, Röösli M. Symptoms in Swiss adolescents in relation to exposure from fixed site transmitters: a prospective cohort study. Environmental Health 2016 Jul 16;15(1):77. 10. Mohammadianinejad SE, Babaei M, Nazari P. The effects of exposure to low-frequency electromagnetic fields in the treatment of migraine headache: a cohort study. Electronic Physician 2016 Dec 25;8(12):3445–9. 11. Heuser G, Heuser SA. Functional brain MRI in patients complaining of electro hypersensitivity after long-term exposure to electromagnetic fields. Reviews on Environmental Health 2017 Sep 26;32(3):291–9. 12. Pall ML. Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects, including depression. Journal of Chemical Neuroanatomy 2016 Sep;75(Pt B):43–51. 13. Gobba F. Subjective non-specific symptoms related with electromagnetic fields: description of 2 cases. Epidemiologia e Prevenzione 2002 Jul–Aug;26(4):171–5. 14. Danker-Hopfe H, Dorn H, Bolz T, Peter A, Hansen ML, Eggert T, Sauter C. Effects of mobile phone exposure (GSM 900 and WCDMA/UMTS) on polysomnography based sleep quality: An intra- and inter-individual perspective. Environmental Research 2016 Feb;145:50–60. 15. Havas M. Radiation from wireless technology affects the blood, the heart, and the autonomic nervous system. Reviews on Environmental Health 2013;28(2–3):75–84. doi: 10.1515/reveh2013-0004. 16. Johansson O. Disturbance of the immune system by electromagnetic fields: a potentially underlying cause for cellular damage and tissue repair reduction which could lead to disease and impairment. Pathophysiology 2009 Aug;16(2–3):157–77. 17. Havas M. Dirty electricity elevates blood sugar among electrically sensitive diabetics and may explain brittle diabetes. Electromagnetic Biology and Medicine 2008;27(2):135–46. 18. Havas M. Electromagnetic hypersensitivity: biological effects of dirty electricity with emphasis on diabetes and multiple sclerosis. Electromagnetic Biology and Medicine 2006;25(4):259–68. 19. De Iuliis GN, Newey RJ, King BV, Aitken RJ. Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro. PLOS One 2009 Jul 31;4(7):e6446. 20. The Independent September 21, 2008: EMF & Health: A Global Issue. September 8-9, 2008, The
Royal Society of London. 21. Gupta M, Khanna R, Rhangra K. Penetration of cell phone and cell tower radiation in human body: a comprehensive study. International Journal of Recent Trends in Engineering & Research 2017 Jul 1;3(7). 22. Roggeveen S, van Os J, Viechtbauer W, Lousberg R. EEG changes due to experimentally induced 3G mobile phone radiation. PLOS One 2015 Jun 8;10(6):e0129496. 23. Tas M, Dasdag S, Akdag MZ, Cirit U, Yegin K, Seker U, Ozmen MF, Eren LB. Long-term effects of 900 MHz radiofrequency radiation emitted from mobile phone on testicular tissue and epididymal semen quality. Electromagnetic Biology and Medicine 2014 Sep;33(3):216–22. 24. Kesari KK, Siddiqui MH, Meena R, Verma HN, Kumar S. Cell phone radiation exposure on brain and associated biological systems. Indian Journal of Experimental Biology 2013 Mar;51(3):187– 200. 25. Khurana VG, Teo C, Kundi M, Hardell L, Carlberg M. Cell phones and brain tumors: a review including the long-term epidemiologic data. Surgical Neurology 2009 Sep;72(3):205–14. 26. Khurana VG, Hardell L, Everaert J, Bortkiewicz A, Carlberg M, Ahonen M. Epidemiological evidence for a health risk from mobile phone base stations. International Journal of Occupational and Environmental Health 2010 Jul–Sep;16(3):263–7.
ACKNOWLEDGMENTS As I’ve dived deeper into the scientific principles and explanations behind functional medicine, I’ve made it a point to understand that the scientists who publish the vast majority of the research papers I’ve read are writing for a very targeted audience (other scientists), and they are not English majors. But without their research, this book, and its practical everyday applications for rejuvenating your brain, would not have been possible. My publishing team has been extraordinary. My Rodale editor, Marisa Vigilante, and her assistant, Danielle Curtis, were integral to this book’s progress. Alyse Diamond at Penguin Random House picked up the project and took it to the finish line. My agents, Celeste Fine and John Maas, have been exemplary. It’s been great to know that I, and this book, are in the hands of pros. I’d like to thank Pamela Liflander, whose editorial support goes way beyond just allowing my ideas to flow freely. Pam organized my flowing ideas, took my calls at every hour of any day, and translated my “geekiness” of segmented ideas into a smooth flowing line of thought, again and again. This body of knowledge would not have come through so clearly without Pam’s patient, flowing pen (actually a keyboard, but you know what I mean). And most important, I must thank my beautiful partner and wife, Marzena, who in the last two years of writing this book has tirelessly listened to me through excitement, confusion, excitement, frustration, excitement, despair, excitement, and everything in between. Thank you Marzi for supporting me in reading 93 research papers on the blood-brain barrier on our honeymoon! You made it so much fun to “geek out” and celebrate our marriage at the same time. There is no one like you in the world. And of course, thanks to you, Dear Reader, for investing the time, and dollars, to read this book. My prayer is that you will see the path to clear the dust and cobwebs from your mind and help insure a long life with a vibrant, energized brain. God knows, we need every one of us thinking more clearly protecting our planet, our children, and our future. Love, peace, and happiness to us all.
ABOUT THE AUTHOR Tom O’Bryan, DC, CCN, DACBN, is an internationally recognized and sought-after speaker and workshop leader for professional educational conferences, events, and consumer health consortiums. His areas of expertise focus on brain health, food sensitivities, environmental toxins, and the development of autoimmune disease. He is the creative visionary behind a series of exclusive private retreats that deep dive to support an individual’s journey out of pain and disease and into a life of vibrant health. He is a frequent contributor to online summits and programs, as well as several bestselling collaborative books and documentaries, including Broken Brain, by Dr. Mark Hyman. Tom O’Bryan is the mind behind the Betrayal documentary series on autoimmune disease (BetrayalSeries.com) and the Gluten Summit (TheGlutenSummit.com), and the author of the bestselling book The Autoimmune Fix (TheAutoimmuneFix.com). He has also created a vast library of content and health-related products on his website, theDr.com, and is the chief medical officer of SunHorseEnergy.com. He is also the founder of the Certified Gluten Practitioner Program (CertifiedGlutenPractitioner.com) and the Advanced Autoimmune Training Program. Dr. O’Bryan also holds positions at the following organizations: Adjunct Faculty, The Institute for Functional Medicine Adjunct Faculty, The National University of Health Sciences Adjunct Faculty, Integrative and Functional Nutrition Academy Clinical Consultant on Functional Medicine, NuMedica Clinical Consultant on Functional Medicine, Vibrant America Editorial Review Board, Alternative Therapies in Health and Medicine Medical Advisory Board, Functional Medicine Coaching Academy Medical Advisory Board, Functional Medicine University Medical Advisory Board, The Institute for Functional Medicine Medical Advisory Board, Nutritional Therapy Association Medical Advisory Board, National Association of Nutrition Professionals Scientific Advisory Board, International and American Association of Clinical Nutritionists To invite Dr. O’Bryan to speak at your event, please visit theDr.com/Inquiries.
What’s next on your reading list? Discover your next great read! Get personalized book picks and up-to-date news about this author. Sign up now.