Research on Animal Testing for Cosmetic Products

BACKGROUND OF THE STUDY Case details:

Animal experimentation and testing for
cosmetic products dates back to the 19th
century, chemists would have to test their
products in order to claim them safe for
general use. The most common victims to
animal experimentation are the rats,
rabbits, and mice. These tests were focused
on determining general toxicity, eye and
skin irritancy, and allergic reactions are
tested by directly applying products on
animal noses, eyes and mouth which in most
cases, cause harm or death to these
animals.

BACKGROUND OF THE STUDY

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BACKGROUND OF THE STUDY Eva Longoria
endorses Loreal

Case details:

In the present day, makeup and other
cosmetic products are widely used by the
majority of the people. Many trends and
styles are set by influencers creating a
high demand in these products and
because of that, there is a lot of
attention being brought to these
cosmetic companies. The huge uproar of
the fight for animal rights and the halt
of animal experimentation caused many
brands to change their process of making
their products.

Don’t be fooled by BACKGROUND OF THE STUDY
claims on a label
stating that a
product wasn’t
tested on animals.

Even if a cosmetics
company does not test
their products or
ingredients on animals, if
they sell their products
in China they cannot be
considered cruelty-free.

BACKGROUND OF THE STUDY Case details:

Many companies claim in their product,
that they do not perform animal testing,
although brands such as Loreal and OPI
that choose to sell in China must
perform animal testing in order to sell
their products there. Any company
making their products outside of China
and exporting them to China for sale
must allow their products to go through
pre-market animal testing which is why
some companies who export to China try
to claim their products are not tested on
animals need to add the disclaimer
“except where required by law”.

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Written and Designed By: Angela Manas Background























EXISTING ALTERNATIVES Witness #1

Dr. Elias Zerhouni

Former U.S. National
Institutes of Health

Director

Statement:

“We have moved away from studying
human disease in humans. … We all
drank the Kool-Aid on that one, me
included. … The problem is that
[animal testing] hasn’t worked, and
it’s time we stopped dancing around
the problem. … We need to refocus
and adapt new methodologies for
use in humans to understand
disease biology in humans.”

Aniamls and humans have different BCAenonnimseafloiutsttewsetiinghg
biological compositions

Witness #2 The company uses EXISTING ALTERNATIVES
In Vitro Testing

Test-tube
experiments of

human cells

and tissues

❖ Creator of “Organs-on-chips”
❖ Human cells are grown in the chips

creating a system that mimics the
structure and function of human
organs and organ systems
❖ Results have shown that the
organs-on-chips replicate human
physiology, diseases, and drug
responses more accurately than
animal experiments

Uses human cells force-feeding studies
and lethal dose tests
= performed on animals
More
accurate
results

EXISTING ALTERNATIVES Witness #3

Also uses

In Vitro Some of the company’s
Testing products...

Epiderm EpiCorneal

Tissue Model Tissue Model

❖ 3D human ❖ 3D human tissue
cell–derived skin model that
model replicates key replicates cells
traits of normal from human eyes
human skin
❖ Assesses drug
❖ Indicates how human delivery, eye
skin would react to infections and
corrosive chemicals diseases, and wound
in skin care healing/tissue
products regeneration

Rcirherepitmlaatciceeaslsthteoenstsitknhigneirooffadbrifialifbteybrittesont Replaces dropping chemicals to
test the time it takes for it to
burn the cornea of a rabbit’s
eye

Witness #4 EXISTING ALTERNATIVES
VITROCELL

AInlsoVuitsreosTesting

❖ These machines expose human lung
cells to chemicals to test the health
effects of inhaled substances

Usage:
❖ On one side, human cells are exposed

to airborne chemical; at the same
time the cells receive nutrients
from a blood-like liquid
❖ By using VITROCELL machines, the
cells are made to mimic the actual
reaction of human lungs to inhaled
substances

Admilftiecfeernresaltnoiwvtelytotxdo:iicefosfrurcboimnstgatnhmceeicsetoxfinoicrtiotyhtouubress, to inhale
letting these

EXISTING ALTERNATIVES Witness #5

Computer (in silico) Modeling

❖ The continuous development of wide
range sophisticated computer models
that simulate and predict the
behaviors present in human biology

❖ These models can accurately predict
the ways that new drugs will react in
the human body

❖ Through the use of quantitative
structure-activity relationships
(QSARs), these computer-based
techniques will approximate the
likelihood of a substance to be
hazardous, based on its similarity to
existing substances and the
knowledge of human biology

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drug tests

Witness #6 htdcoAuuanmencimaonmtnaootslmstubhaneericieractoeninnosatwebniialtintthyedd EXISTING ALTERNATIVES

Human Volunteers
procedures are only
performed with consent and
out of the volunteers’ own

volition

❖ Volunteers are given a
❖ small one-time drug dose
Imaging techniques will
❖ monitor the bodies’
reaction to the drug
MICRODOSING Screens out drug compounds
that will not work in
❖ humans, so researchers
don’t have to needlessly
❖ pursue research in animal
tests
Functional magnetic An advanced brain imaging
resonance imaging and recording technique
(fMRI) which allows the detailed
study of human brains, down
to the level of a single
neuron
Prevents damaging brains
of animals that are used for
thorough research of
effects of cosmetic drugs
onto their neurosystems

Written and Designed By: Doris Wu Existing Alternatives

CONCLUSION AND RECOMMENDATIONS Case details:

The cons of using
animal-testing for cosmetic
products outweighs its benefits.
Additionally, the use of animals in
testing raises an ethical issue. It
has been a topic of ethical debate
which hinders the use of its
maximum potential.

IMPLEMENT ALTERNATIVES
STOTPESATNIINMGAL

Ethical views: fAisonrimucnaoelstmtheeicstaticilnsg CONCLUSION AND RECOMMENDATIONS

Deontology

subject of a life

Sentiocentrism

capacity for suffering

Justice and Fairness

seen behind a veil of
ignorance

Environmental Ethics

right to a share fair of existence

Ethics of Care
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we them
have

CONCLUSION AND RECOMMENDATIONS Evidences: Alternatives are achievable

Cruelty-free Cosmetic Companies

KYLIE COSMETICS
ANASTASIA BEVERLY HILLS

Case details: CONCLUSION AND RECOMMENDATIONS

With the availability of possible
alternatives, the use of animal-testing
for cosmetic products can be avoided.
Through the use of the alternatives, the
ethical problem can be solved while
retaining the benefits of
animal-testing. It is also recommended
to use various alternatives to maximize
its benefits. With this, cosmetic
companies should adhere to ethical
standards.

CCF Support the
cruelty-free
PETA movement!!

Leaping bunny Jan Josef Domingo CASE CLOSED

Written and Designed By: Conclusion and
Recommendations

BBC. (n.d.). The ethics of speciesism. Retrieved from
http://www.bbc.co.uk/ethics/animals/rights/speciesism.shtml#:~:text='Speciesism'%20is%20the%20ide
a%20that,of%20members%20of%20other%20species.

Blattner, C. (2019). The Recognition of Animal Sentience by the Law. Journal of Animal Ethics, 9(2), 121-136.
Retrieved from https://www.jstor.org/stable/10.5406/janimalethics.9.2.0121

Engster, D. (2006). Care Ethics. Journal of Social Philosophy, 37(4), 521-536. Retrieved from
https://webs.wofford.edu/williamsnm/animal%20ethics%20articles/care%20ethics%20and%20animal%
20welfare.pdf

Festing, S. & Wilkinson, R. (2007, May 18). The ethics of animal research: Talking Point on the use of animals in
scientific research. EMBO reports, 8, 526-530. Retrieved from https://doi.org/10.1038/sj.embor.7400993

Goldacre, B. (2010, Jan 22). Animal research study shows many tests are full of flaws. Retrieved from
https://www.theguardian.com/science/2010/jan/23/ben-goldacre-bad-science

History of Animal Testing. (2020). Retrieved from https://animal-testing.procon.org/history-of-animal-testing/
Layne , J. (2020). Ablison Energy. Important Pros and Cons of Animal Testing. Retrived from

https://www.ablison.com/pros-and-cons-of-animal-testing/
Lenhard, E. (2018, December 7). The human-animal bond throughout time. Retrieved from

https://cvm.msu.edu/news/perspectives-magazine/perspectives-fall-2018/the-human-animal-bond-thro
ughout-time
MatTek. (2020). EpiCorneal. Retrieved from https://www.mattek.com/products/epicorneal/
MatTek. (2020). EpiDerm. Retrieved from https://www.mattek.com/products/epiderm/
McManus, R. (2013). Ex-director Zerhouni surveys value of NIH research. NIH Record, LXV(13), pp. 6-7. Retrieved
from https://nihrecord.nih.gov/sites/recordNIH/files/pdf/2013/NIH-Record-2013-06-21.pdf
People for the Ethical Treatment of Animals. (2020). Cruelty in animal testing laboratories. Retrieved from
https://www.peta.org/issues/animals-used-for-experimentation/cosmetic-household-products-animal-t
esting/
Regoli, N. (2018). ConnectUS. 16 Key Advantages and Disadvantages of Animal Testing in Cosmetics. Retrived from
https://connectusfund.org/16-key-advantages-and-disadvantages-of-animal-testing-in-cosmetics
The Humane Society of the United States. (2020). Cosmetics testing faq. Retrieved from
https://www.humanesociety.org/resources/cosmetics-testing-faq
Vitrocell. (2020). Vitrocell® exposure systems for inhalation toxicology. Retrieved from
https://www.vitrocell.com/inhalation-toxicology/fbclid/iwar0th0gparmr2aeqdp174zzdniqz1hdj3iyewx_v
r5dz4k5w6uhc7ooed5y
Walls, D. (2014, November 9). Animal rights movement. Retrieved from
https://web.sonoma.edu/users/w/wallsd/animal-rights-movement.shtml#:~:text=Animal%20Rights%20
Movement,-(PDF%3A%2019k)&text=The%20Animal%20Protection%20Movement.,the%20movement%2
0for%20woman%20suffrage
World Animal Net. (n.d.). Brief history of the animal protection movement. Retrieved from
http://worldanimal.net/our-programs/strategic-advocacy-course-new/module-1/history