NBME 7 BLOCK 1-4 (with Answers)

The sarcoplasmic reticulum serves as a repository for Ca++.
1.In rested muscle, Ca++ is found in high concentration in the cisternae at the triad.
2.In recently active muscle, the calcium is found in the narrowed, longitudinal portion
from which it moves to the triad as time passes.
3.During contraction, Ca++ is found in high concentration outside the sarcoplasmic
reticulum among the myofilaments



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dislocated hip is a condition that can be congenital or acquired. Congenital hip
dislocations are much more common in girls than in boys.

















adenocarcinoma of prostate gland... prostate gland cancer metastasizes to vertebrae via the venous plexus around it... B
is keratin pearls of squamous cell cancer so cant be it, D is basophil u can never find a basophil in cancer, E is uniform
cells, cancer is never uniform cells, they are anaplastic cells, A is agrregates of plasma cell and plasma blasts this
feature is of multiple myeloma

















Patient had CHF, "LVF", always if pulmonary edema LHF the main symptom the SOB
Can't get blood out of the heart b/c the LV fails, increased the EDV because all the blood can not get out, then the
pressure and volume will go back to the left atrium, back into the pulmonary vessels, increased the hydrostatic pressure
and then PULMONARY EDEMA
What happen in the CHF?: Decreased the cardia output regulated by RAA System like the Blood pressure, the renal perfusion
is decreased then the renin increases---- renin convert angiotensinogen into angiotensin I. ACE found mainly in
endotelial cells of pulmonary vessels, converts angiotensin I into angiotensin II. Angiotensin II has a potent effects to
stimulate secretion of aldosterone and to cause arteriolar vasoconstriction. stimulates reabsorption of Na+ and ALSO
Cause increased renal excretion of potassium affecting the plasma K_ concentration









Acne vulgaris (or acne) is a common human skin disease, characterized by areas of skin
with seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules
(pinheads), pustules (pimples), nodules (large papules) and possibly scarring.[1] Acne
affects mostly skin with the densest population of sebaceous follicles; these areas
include the face, the upper part of the chest, and the back. Severe acne is inflammatory,
but acne can also manifest in noninflammatory forms.[2] The lesions are caused by
changes in pilosebaceous units, skin structures consisting of a hair follicle and its
associated sebaceous gland, changes that require androgen stimulation
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