Rehabilitation of lexical retrieval in aphasia: Evidence ...

Participant Pre tx Time post
WAB AQ onset CVA

(months)

Well define categories (Kiran & Johnson, sub
P1 82.5 11

P2 84.3 7
P3 87.3 36

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

t Category Generalization trends
A Trained
) Atypical => Typical

bmitted) Typical ≠› Atypical
1. Shapes
Atypical => Typical
1. Shapes

1. Shapes

Kiran & Johnson (2008)

Participant Pre tx Time post
WAB AQ onset CVA

(months)

Well define categories (Kiran & Johnson, sub
P1 82.5 11

P2 84.3 7

P3 87.3 36

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

t Category Generalization trends
A Trained
) Atypical => Typical

bmitted) Typical ≠› Atypical
1. Shapes
Atypical => Typical
1. Shapes

1. Shapes

Kiran & Johnson (2008)

Ad hoc ca

Camera Bicycle
Cup

C
Things at garage sale

Jewelry Lamp Mugs
Candle

Chairs Pillow

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

ategories

Pens • Entertainment
• Items for travel
Clock • Household
Antique
items
w • Memorabilia
• Unwanted/not

needed
• For kids
• Things with

newer formats
• Things that get

replaced
• Things for

reading

Dependent variable in baseline
Generative naming of category
“Please name as many items th
sale”

Typical items (N =15)
Atypical items (N =15)

Normed for variables

Classification of r
subcategories (N
kitchen items, ho

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

e and treatment probes:
items

hat you could have in a garage

Other items in the category that
were generated by participant
Not normed

responses into
N = 10) (e.g.,
ome/garden)

Generative nam ing of target atypical w ords for categ
garage sale

100%
90%
80%
70%
60%
50%
40%
30%
20%
10%

0%

1 2 3 4 5 6 7 8 9 10
P r obe s

Total generative naming of other w ords for category garage sale

100

Number of target + acceptable 90
responses
80

70

60

50

40

30

20

10

0
1 2 3 45 6 78 9

Pr obe s

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RESEARCH LABORATORY

gory

Typical- unt r ained
At ypical- t rained

Things to have at
garage sale

11 12 Typical Atypical
Pants Antiques,
Jewelry Camera
Clock Movies
Candle

10 11

Summary: Tre

Particip Age Pre tx Time post

ant WAB AQ onset CVA
(months)

P1 76 79 30 1.

P2 39 82 6 1.
2.

P3 76 84.3 108 1.

P4 69 72.1 10 1.
2.

P5 84 70.9 9 1.

P6 64 84.8 96 1.

BOSTON UNIVERSITY APHASIA tx criterion of

* Did not achieveRESEARCH LABORATORY

eatment effects

Category Trained Generalization trends

. Things at garage sale Atypical => Typical
Things to take camping Atypical => Typical
. Things at garage sale Typical => Atypical
. Things at garage sale Atypical => Typical
Things to take camping * Typical ≠› Atypical
. Things at garage sale * Atypical => Typical
Things to take camping * Typical ≠› Atypical
. Things at garage sale Atypical => Typical

80% accuracy across 2 sessions

Summary: Tre

Particip Age Pre tx Time post

ant WAB AQ onset CVA
(months)

P1 76 79 30 1.

P2 39 82 6 1.
2.

P3 76 84.3 108 1.

P4 69 72.1 10 1.
2.

P5 84 70.9 9 1.

P6 64 84.8 96 1.

BOSTON UNIVERSITY APHASIA tx criterion of

* Did not achieveRESEARCH LABORATORY

eatment effects

Category Trained Generalization trends

. Things at garage sale Atypical => Typical

Things to take camping Atypical => Typical
. Things at garage sale Typical => Atypical

. Things at garage sale Atypical => Typical

Things to take camping * Typical ≠› Atypical
. Things at garage sale
* Atypical =>
Typical

Things to take camping * Typical ≠› Atypical

. Things at garage sale Atypical => Typical

80% accuracy across 2 sessions

Summary: Tre

Particip Age Pre tx Time post

ant WAB AQ onset CVA
(months)

P1 76 79 30 1.

P2 39 82 6 1.
2.

P3 76 84.3 108 1.

P4 69 72.1 10 1.
2.

P5 84 70.9 9 1.

P6 64 84.8 96 1.

BOSTON UNIVERSITY APHASIA tx criterion of

* Did not achieveRESEARCH LABORATORY

eatment effects

Category Trained Generalization trends

. Things at garage sale Atypical => Typical
Things to take camping Atypical => Typical
. Things at garage sale Typical => Atypical
. Things at garage sale Atypical => Typical
Things to take camping * Typical ≠› Atypical
. Things at garage sale * Atypical => Typical
Things to take camping * Typical ≠› Atypical
. Things at garage sale Atypical => Typical

80% accuracy across 2 sessions

Number of observations Summary of tre

14
12
10

8
6
4
2
0

Training typical examples

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

eatment studies

Generalization
No generalization
Training atypical examples

Theoretical A

CHURC

Hymn

Parish

Candle

Minister

BOSTON UNIVERSITY APHASIA Kiran, S
RESEARCH LABORATORY

Assumption

CH Concrete words

Steeple

Bible

Sandberg, & Abbott, in press

Theoretical A

CHURC

Parish Hymn
Candle Holy

Blessing

Solace
Minister

BOSTON UNIVERSITY APHASIA Kiran, S
RESEARCH LABORATORY

Assumption

CH Concrete words

y Steeple Abstract words

Penance
Bible

Prayer

Sandberg, & Abbott, in press

Hypothesis an

Parish Hymn

Candle Prayer Steeple

Minister Bible

TRAINING ABSTRACT WORDS

UNTRAINED CONCRETE WORDS

BOSTON UNIVERSITY APHASIA Kiran, S
RESEARCH LABORATORY

nd Predictions

Blessing Angel

Solace Candle Belief

Forgiveness Penance

TRAINING CONCRETE WORDS
UNTRAINED ABSTRACT WORDS

Sandberg, & Abbott, in press

Treatment

Sorting word cards by related location
Select target word (N = 10)

Select 6 written semantic features
from distracters for each target

Ca

Respond to 15 auditorily as
presented questions with

(5 accurate, 5 inaccurate, 5 distracter)

Word recall of trained items W

BOSTON UNIVERSITY APHASIA Kiran, S
RESEARCH LABORATORY

t Protocol

Church, Courthouse and Hospital

Minister

Is alive Has a physical presence
Can be seen Conveys important messages
an be touched
Exists outside the mind

Is it Is it a place to Does it live in
ssociated pray? trees?
h heaven?

What are we talking about? Minister

Sandberg, & Abbott, in press

Number of items Generative naming for target abstract and concrete
HOSPITAL

10
9
8
7
6
5
4
3
2
1
0
1 2 3 4 5 6 7 8 9 10 11 12
Probe num ber

Generative naming for target abstract and concrete
Abstract-untrained
COURTHOUSE
10 Concrete-trained

9

8

Number of items 7

6

5

4

3

2

1

0

1 2 3 4 5 6 7 8 9 10 11 12

BOSTON UNIVERSITY APHASIA Probe num be r
RESEARCH LABORATORY

e words P3

Abstract-trained

Concrete-untrained

HOSPITAL
• Trained abstract ES = *
• Untrained concrete ES = 4.2

13 14 15

e words

COURTHOUSE
• Trained concrete ES = 6.89
• Untrained abstract ES = 2.3

13 14 15

Kiran Sandberg & Abbott in press

Summary

Ps Category Typicality Gen
trained trained patt

P1 1. Church Abstract Abs

2. Hospital Concrete Con

P2 1. Church Abstract Abs

2. No treatment

P3 1. Hospital Abstract Abs

2. Courthouse Concrete Con

P4 1. Church Concrete Con
2. Hospital Abstract

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RESEARCH LABORATORY

of results

neralization No learning,
terns observed no generalization
stract ≠› Concrete
No learning,
ncrete ≠› Abstract no generalization

stract => Concrete Generalization

stract => Concrete Generalization
ncrete ≠› Abstract No generalization
ncrete ≠› Abstract No generalization

Summary

Ps Category trained Typicality Gen

trained obse

P1 1. Church Abstract Abs

2. Hospital Concrete Con

P2 1. Church Abstract Abs

2. No treatment

P3 1. Hospital Abstract Abs
2. Courthouse Concrete Con

P4 1. Church Concrete Con
2. Hospital Abstract Abs

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

of results

neralization patterns
erved

stract ≠› Concrete No learning,
no generalization

ncrete ≠› Abstract No learning,
no generalization

stract => Concrete Generalization

stract => Concrete Generalization
ncrete ≠› Abstract No generalization

ncrete ≠› Abstract No generalization

stract => concrete Generalization

Summary

Ps Category trained Typicality Gen

trained obse

P1 1. Church Abstract Abs

2. Hospital Concrete Con

P2 1. Church Abstract Abs

2. No treatment

P3 1. Hospital Abstract Abs
2. Courthouse Concrete Con

P4 1. Church Concrete Con
2. Hospital Abstract

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

of results

neralization patterns No learning,
erved no generalization
stract ≠› Concrete
No learning,
ncrete ≠› Abstract no generalization

stract => Concrete Generalization

stract => Concrete Generalization
ncrete ≠› Abstract No generalization
ncrete ≠› Abstract No generalization

A: Normal category representation Typic
examp

Semantic Robin
representation Lay eggs, has beak
Small, hops, flies

Phonological ROBIN SPAR
representation

BOSTON UNIVERSITY APHASIA

KirRaEnSEA(2RC0H0L7A)BOARJASTOLRPY

cal Atypical
ples examples

Sparrow Penguin Ostrich
Lay eggs, has beak Lay eggs, has beak Lay eggs, has beak
Small, hops, flies Webbed feet, eats fish Long neck, long legs

RROW PENGUIN OSTRICH

A: Normal category representation Typic
examp

Semantic Robin
representation Lay eggs, has beak
Small, hops, flies

Phonological ROBIN SPAR
representation
Robin S
B: Effect of treatment Lay eggs, has beak L
Small, hops, flies S
Training Atypical
Examples

ROBIN SP

Kiran (B2OS0T0O7N)UANIJVSERLSIPTY APHASIA
RESEARCH LABORATORY

cal Atypical
ples examples

Sparrow Penguin Ostrich
Lay eggs, has beak Lay eggs, has beak Lay eggs, has beak
Small, hops, flies Webbed feet, eats fish Long neck, long legs

RROW PENGUIN OSTRICH

Sparrow Penguin Ostrich
Lay eggs, has beak Lay eggs, has beak Lay eggs, has beak
Small, hops, flies Webbed feet, eats fish Long neck, long legs

PARROW PENGUIN OSTRICH

A: Normal category representation Typic
examp

Semantic Robin
representation Lay eggs, has beak
Small, hops, flies

Phonological ROBIN SPAR
representation
Robin S
B: Effect of treatment Lay eggs, has beak L
Small, hops, flies S
Training Atypical
Examples

ROBIN SP

C: Effect of treatment Robin
Lay eggs, has beak
Small, hops, flies

Training Typical
Examples

ROBIN SP

BOSTON UNIVERSITY APHASIA

KirRaEnSEA(2RC0H0L7A)BOARJASTOLRPY

cal Atypical
ples examples

Sparrow Penguin Ostrich
Lay eggs, has beak Lay eggs, has beak Lay eggs, has beak
Small, hops, flies Webbed feet, eats fish Long neck, long legs

RROW PENGUIN OSTRICH

Sparrow Penguin Ostrich
Lay eggs, has beak Lay eggs, has beak Lay eggs, has beak
Small, hops, flies Webbed feet, eats fish Long neck, long legs

PARROW PENGUIN OSTRICH

Sparrow Penguin Ostrich
Lay eggs, has beak Lay eggs, has beak Lay eggs, has beak
Small, hops, flies Webbed feet, eats fish Long neck, long legs

PARROW PENGUIN OSTRICH

• Training atypical example
than typical examples to
generalization

• Patients also show consis
language measures

• Are behavioral changes a
changes in the brain?

• What are regions that can
language recovery after t

BOSTON UNIVERSITY APHASIA
RESEARCH LABORATORY

es may be more efficient
facilitate within category
stent improvements on
associated with functional

n support behavioral
treatment?