Procedure and Reasons for Laser Hatching of Cleavage Stage Embryos in IVF To successfully attach to the uterine wall, an embryo must first hatch from its protective outer layer, known as the zona pellucida. Laser hatching in IVF serves to thin this layer, facilitating the embryo's hatching process and potentially improving pregnancy success rates, especially when using Day 3 embryos. This laboratory procedure is commonly recommended for women over 37 years of age and those with elevated Day 3 follicle-stimulating hormone (FSH) levels. Laser hatching in IVF may also be particularly beneficial for: Embryos with an abnormally thick or tough outer shell Slow-developing or poor-quality embryos Patients with two or more unsuccessful IVF cycles Embryos with excessive fragmentation Frozen-thawed embryo transfer cycles The laser hatching procedure The laser hatching process occurs during the IVF cycle while the Day 3 embryo is still in the lab. Before implanting the embryo into the uterus, its zona pellucida is carefully thinned using quick pulses of laser energy. The procedure is safe. The laser does not damage the embryo's cells and takes only a few seconds to complete. This minimises the time the embryo spends outside its incubator. Advantages of laser hatching
Laser-assisted hatching is often recommended for individuals who have experienced multiple failed IVF cycles. While embryos naturally undergo a process called zona lysis to hatch, some fail to implant because the trophectoderm struggles to release lysing agents, making it impossible for the embryo to exit its shell. Laser hatching in IVF can also assist older women trying to conceive and those with embryos having a thicker zona pellucida. Additionally, it can be beneficial for women with unexplained infertility and recurrent implantation failures. Efficacy and safety One of the most compelling aspects of laser hatching in IVF is its safety profile. There are no known risks or side effects associated with the procedure, making it a worthwhile consideration for those looking to improve their chances of pregnancy. Current research also supports its safety, indicating that laser hatching doesn't cause abnormalities in the baby. This is because the procedure targets only the embryo's outer shell, leaving its inner structure untouched. Should you consider laser hatching? The most effective way to determine if laser hatching in IVF is suitable for you is to consult a fertility specialist. At Advance Fertility &Gyne Centre, our team specialises in addressing failed IVF cycles and other infertility challenges. Schedule an appointment today to explore your options. About the Company Advance Fertility and Gynae Centre is a leading IVF centre in India, located in Delhi NCR. It offers high-quality IVF services with guaranteed success at affordable prices. The centre is led by renowned infertility expert Dr Kaberi Banerjee and a team of qualified fertility experts. They have a state-of-the-art embryology laboratory equipped with the latest equipment for successful treatments, even in challenging cases. The centre focuses on comprehensive treatment for both couples, performing procedures like In Vitro Fertilization (IVF) and Intra Uterine Inseminations based on individual needs. They also provide cryopreservation facilities for future use if necessary and maintain excellent post-operative care for patients undergoing IVF procedures or laparoscopic/hysteroscopic procedures.