No. of Centre 8 2 4 5
Tc-99m In-111 Ga-67 Cr-51
9
8
7
6
5
4
3
2
1
0
4
3
3
2
No. of Centre 2
11111 11
1
0
98 8
8
7
6 5
No. of Centre 5
4
3
2 11 1
1
0
5
4
4
333
3
No of Centre 2
2
11
1
0
β
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Percentage of 200 **
2-deoxy[1-3H]glucose uptake
150 *** *
relative to control
(dpm/105 cells/60min) 100
50
0 Basal With 100 nM
Control 100nM 100 g/ml insulin
Insulin
10 g/ml 50 g/ml 500 g/ml 1000 g/ml
250
Percentage of 200 * *** *** ** *** *** *** *** ***
2-deoxy[1-3H]glucose uptake
***
relative to control
(dpm/105 cells/60min) 150
100
50
0 100nM Basal With 100 nM
Control Insulin 100 g/ml insulin
10 g/ml 50 g/ml 500 g/ml 1000 g/ml
Percentage of 300 *** ** *** ***
2-deoxy[1-3H]glucose uptake
200 ***
relative to control
(dpm/105 cells/60min) *** **
100
0 Basal With 100 nM
Control 100nM 100 g/ml insulin
Insulin
10 g/ml 50 g/ml 500 g/ml 1000 g/ml
Percentage of 2-deoxy[1-3H]glucose 400
uptake relative to control 300 ***
(dpm/105 cells/60min) ***
200 ***
*** ***
100
***
***
**
0 Insulin Basal With Insulin 100nM
Control 100nM
500M
50M 100M 1000M 2000M
β
β
μ
μ
Activity of 68Ga in anion column after elution x 100%
Syringe activity of 68Ga before the elution - Syringe activity of 68Ga after the elution
68Ga activity in elution vial x 100%
68Ga activity in anion exchange column before desorption
Percentage of Ga-68 adsorption 100 83.74 86.66 90.67 97.07 96.72 96.69 96.77
90
80
70
60
50
40 Average %Ga-68
Adsorption
30
20
10
0
4.0 4.5 5.0 5.5 6.0 6.5 7.0
HCl Molarity
Percentage of Ga-68 adsorption 100 93.33 94.13 95.07 98.3 98.17 98.24 98.17 Average %Ga-68 adsorption
90
80
70
60
50
40
30
20
10
0
4.0 4.5 5.0 5.5 6.0 6.5 7.0
HCl Molarity
Percentage of Ga-68 adsorption 100 98.3 97.97 98.06 98.4
86.38
90
80 68.28 73.04
70
60
50 Average %Ga-68
40 adsorption
30
20
10
0
4.0 4.5 5.0 5.5 6.0 6.5 7.0
HCl Molarity
80 70.36 70.49
70
Ga-68 Desorption (%) 60 58.56
50
40 Chromafix Oasis WAX
30
20
10
0
AG 1-X8
2H 3H 24He n 3H (d, n)4He
nht (x, D) = Fh(x)ht ( ox (x()[Nht (x) - nht (x)] - Fe (x)r ox (x))nht(x)
nht
N ht
r
Fh Fe
Vot Vot
Vot = -(q/ ox ) doxNot
Not Not
N ot= 1 d ox nht(x)xdx
dox 0
E (MeV) s
E(MeV) cos /c
D 4.8 barn
(N D )1 (51022 4.81024)1 4cm
n / 4
ns 500
α