Triderm cream is formulated for treating exudative-stage skin disorders, unsuitable for eye use. Discontinue if irritation or hypersensitivity arises, opting for proper therapy. Extensive or prolonged topical application might heighten systemic absorption, leading to systemic side effects akin to internal medication.

Spazmalgon is employed for symptomatic relief of mild to moderate pain and smooth muscle cramps within internal organs. It's effective for renal colic, urinary tract inflammation with associated pain, gastrointestinal spasms, liver colic, biliary dyskinesia, and spastic dysmenorrhea. Individuals hypersensitive to metamizol or pyrazolone derivatives, as well as those with certain gastrointestinal, renal, or liver conditions, should avoid its use. Administered orally after meals with water, the recommended daily dosage for adults and 15-year-old children is 1-2 tablets, not exceeding 2 tablets per day. Treatment duration should not surpass 3 days.

Triderm cream is formulated for treating exudative-stage skin disorders, unsuitable for eye use. Discontinue if irritation or hypersensitivity arises, opting for proper therapy. Extensive or prolonged topical application might heighten systemic absorption, leading to systemic side effects akin to internal medication.

Acute NSAID overdose symptoms include reversible effects like apathy, drowsiness, nausea, vomiting, and epigastric pain. Rarely, serious complications such as gastrointestinal bleeding, arterial hypertension, renal failure, and respiratory depression may arise. Anaphylactoid reactions are possible even with therapeutic doses. Overdose treatment involves symptomatic support; no specific antidotes exist. Nimesulide's high protein binding reduces effectiveness of measures like hemodialysis. Within 4 hours of overdose, vomiting, activated charcoal, or laxatives can be considered. Kidney and liver function monitoring is crucial, while interventions like forced diuresis may prove ineffective due to protein binding.

Triderm Cream, available in a 30g formulation, is designed to target conditions in the exudative stage, helping to alleviate discomfort and promote healing. Not intended for ocular use, this cream offers focused relief for various skin issues. Should signs of irritation or hypersensitivity emerge during treatment, prompt cessation and exploration of alternative therapies tailored to the patient's needs are recommended. When topically applied, Triderm Cream may enhance absorption of active ingredients into the bloodstream. Caution is advised when using on extensive or damaged skin areas or for prolonged periods, as this heightened systemic absorption may potentially lead to reactions akin to systemic substance administration.

Triderm Cream, available in a 30g formulation, is designed to target conditions in the exudative stage, helping to alleviate discomfort and promote healing. Not intended for ocular use, this cream offers focused relief for various skin issues. Should signs of irritation or hypersensitivity emerge during treatment, prompt cessation and exploration of alternative therapies tailored to the patient's needs are recommended. When topically applied, Triderm Cream may enhance absorption of active ingredients into the bloodstream. Caution is advised when using on extensive or damaged skin areas or for prolonged periods, as this heightened systemic absorption may potentially lead to reactions akin to systemic substance administration.

Symptoms of acute NSAID overdose are usually limited to the following: apathy, drowsiness, nausea, vomiting and epigastric pain, which are usually reversible with maintenance therapy. Gastrointestinal bleeding is possible. Rarely possible arterial hypertension, acute renal failure, respiratory depression and coma. There have been reports of anaphylactoid reactions when using therapeutic doses of NSAIDs, which can occur in case of overdose. In case of overdose of NSAIDs, patients should be provided with symptomatic and supportive treatment. There are no specific antidotes. There is no information on the withdrawal of nimesulide by hemodialysis, but if we take into account its high degree of binding to plasma proteins (up to 97.5%), it is unlikely that dialysis will be effective in overdose. In the presence of symptoms or after a severe overdose within 4 hours after taking the drug, patients can be prescribed vomiting and / or activated charcoal (60-100 g for adults), and / or an osmotic laxative. Forced diuresis, urinary obstruction, hemodialysis, or hemoperfusion may be ineffective due to the high degree of protein binding. Kidney and liver function should be monitored.

Symptoms of acute NSAID overdose are usually limited to the following: apathy, drowsiness, nausea, vomiting and epigastric pain, which are usually reversible with maintenance therapy. Gastrointestinal bleeding is possible. Rarely possible arterial hypertension, acute renal failure, respiratory depression and coma. There have been reports of anaphylactoid reactions when using therapeutic doses of NSAIDs, which can occur in case of overdose. In case of overdose of NSAIDs, patients should be provided with symptomatic and supportive treatment. There are no specific antidotes. There is no information on the withdrawal of nimesulide by hemodialysis, but if we take into account its high degree of binding to plasma proteins (up to 97.5%), it is unlikely that dialysis will be effective in overdose. In the presence of symptoms or after a severe overdose within 4 hours after taking the drug, patients can be prescribed vomiting and / or activated charcoal (60-100 g for adults), and / or an osmotic laxative. Forced diuresis, urinary obstruction, hemodialysis, or hemoperfusion may be ineffective due to the high degree of protein binding. Kidney and liver function should be monitored.