CAPTUS 600 Manual

CAPINTEC, INC. CAPTUS® 600

Cs137 STANDARD SETUP

All calibration of the Capintec CAPTUS® 600 is done with a Cesium-137 standard reference

source. Before using this source to calibrate the system, the source calibration data must be
input in the CAPTUS® 600 memory.

Press the HOME key then the UTIL key. The main Utilities menu (Figure 5-10) will appear.

UTILITIES 14:32

1. MULTICHANNEL ANALYZER
2. STAFF BIO ASSAY RESULTS
3. SETUP
4. DIAGNOSTICS

0. RETURN TO PROBE SCREEN

Figure 5-10

Press 3 to select SETUP. The message “PASSWORD:” will appear. Type the last three digits
of your CAPTUS® 600 serial number, and press the ENTER key. The Setup menu (Figure 5-

11) will appear.

SETUP 14:32

1. Ci/Bq
2. TEST DATA
3. THYROID UPTAKE
4. BIO ASSAY
5. AUTO CALIBRATION
6. ACTIVITY CONVERSION FACTORS
7. WIPE AND MCA SETUP
8. OTHER

0. RETURN TO UTILITIES MENU

Figure 5-11

Press 2 to select TEST DATA. The Test Data menu (Figure 5-12) will appear.

November 07 SYSTEM INITIALIZATION 5-7

CAPINTEC, INC. CAPTUS® 600

14:32
1. CS137 STANDARD
2. CHI-SQUARE PROTOCOL

0. Return to Setup Menu

Figure 5-12

Press 1 to select CS137 STANDARD. The Cs137 Standard Probe/Well Selection Screen
(Figure 5-13) will appear.

CS137 Standard 14:32
1. W ell
2. Probe

0. Return to Previous Screen

Figure 5-13

Select which detector the standard is for by pressing 1 for WELL or 2 for PROBE. Even if you
have a single probe and use it as Probe and Well, you must still enter a Cs137 Standard for
both. The Cs137 Standard Screen (Figure 5-14) will appear.

The word “PROBE” or “WELL” will appear on the screen to indicate which standard is being
entered. The same standard may be used for both Probe and Well but data must be input for
each in this section.

5-8 SYSTEM INITIALIZATION November 07

CAPINTEC, INC. CAPTUS® 600

CS137 Standard 14:32
PROBE

Source ID :> CS1
Calib Activity : 0.11 μCi
Calib Date : Jan 06, 1992

NUM OK
Figure 5-14

For the Source ID, input an identification name for the source. This name can include letters
and/or numbers.

Press F1 [NUM] to switch to numeric input for the Source ID and display “LET” for F1.

Press F1 [LET] to switch back to letter input for the Source ID and display “NUM” for F1.

Input the calibrated activity of the Cesium-137 source.

Input the calibration date of the Cesium-137 standard source in the format chosen in Utilities,
Date Entry Format.

Press the F4 [OK] when all the entries are correct.

CHI-SQUARE TEST SETUP

Press the HOME key then the UTIL key to display the main Utilities menu (Figure 5-15).

UTILITIES 14:32

1. MULTICHANNEL ANALYZER
2. STAFF BIO ASSAY RESULTS
3. SETUP
4. DIAGNOSTICS

0. RETURN TO PROBE SCREEN

Figure 5-15

November 07 SYSTEM INITIALIZATION 5-9

CAPINTEC, INC. CAPTUS® 600

Press 3 to select SETUP. The message “PASSWORD:” will appear. Type the last three digits
of your CAPTUS® 600 serial number, and press the ENTER key. The Setup menu (Figure 5-

16) will appear.

SETUP 14:32

1. Ci/Bq
2. TEST DATA
3. THYROID UPTAKE
4. BIO ASSAY
5. AUTO CALIBRATION
6. ACTIVITY CONVERSION FACTORS
7. WIPE AND MCA SETUP
8. OTHER

0. RETURN TO UTILITIES MENU

Figure 5-16

Press 2 to select TEST DATA. The Test Data menu (Figure 5-17) will appear.
14:32

1. CS137 STANDARD
2. CHI-SQUARE PROTOCOL

0. Return to Setup Menu

Figure 5-17

Press 2 to select the CHI-SQUARE PROTOCOL. The Chi-Square Protocol Screen (Figure 5-
18) will appear.

5-10 SYSTEM INITIALIZATION November 07

CAPINTEC, INC. CAPTUS® 600

CHI-SQUARE PROTOCOL 14:32

REPETITIONS: >10

COUNTING TIME: 30 SEC

OK

Figure 5-18

Input the number of repetitions desired (the minimum is 5 and the maximum is 30; at least 10
repetitions is recommended).

Input the counter time for each measurement (the minimum is 10 seconds and the maximum
is 9999 seconds).

Press F4 [OK] when the correct entries have been made.

CONVERSION FACTORS

Conversion Factors are constants used to convert measurements in counts per minute (cpm)
to disintegrations per minute (dpm). The CAPTUS® 600 calculates dpm values by multiplying
the cpm measurement by the Conversion Factor of a particular nuclide. Conversion Factor
values are affected by geometry, detector efficiency, abundance of the gamma energy
peak(s) of the isotope, and the Region of Interest selected for that nuclide.

You can store Conversion Factors for all of the radionuclides already stored in your
CAPTUS® 600 and for ten additional user-defined radionuclides, and for a “generic” nuclide.

Since some radiation safety regulations require you to document wipe test monitoring results
in dpm units, you should store Conversion Factors for the nuclides that could be present in a
wipe sample.

The CAPTUS® 600 calculates Conversion Factors by measuring counts (in cpm) from a
calibrated sample of a specific radionuclide. Because the sample is calibrated, the CAPTUS®
600 can calculate the dpm value of that sample. The CAPTUS® 600 then divides the dpm
value by the cpm value to determine the Conversion Factor (CF) for that nuclide.

CF for radionuclide = disintegrations per minute
counts per minute

November 07 SYSTEM INITIALIZATION 5-11

CAPINTEC, INC. CAPTUS® 600

To access the Conversion Factors section, press the HOME key, then the UTIL key to
display the main Utilities menu (Figure 5-19).

UTILITIES 14:32

1. MULTICHANNEL ANALYZER
2. STAFF BIO ASSAY RESULTS
3. SETUP
4. DIAGNOSTICS

0. RETURN TO PROBE SCREEN

Figure 5-19

Note: Selection 0 will display “RETURN TO WELL SCREEN” if the Utilities menu is
accessed from the Well Main Screen.

Press 3 to select SETUP. The message “PASSWORD:” will appear. Type the last three digits
of your CAPTUS® 600 serial number, and press the ENTER key. The Setup menu (Figure 5-
20) will appear.

SETUP 14:32

1. Ci/Bq
2. TEST DATA
3. THYROID UPTAKE
4. BIO ASSAY
5. AUTO CALIBRATION
6. ACTIVITY CONVERSION FACTORS
7. WIPE AND MCA SETUP
8. OTHER

0. RETURN TO UTILITIES MENU

Figure 5-20

Press 6 to select ACTIVITY CONVERSION FACTORS. The Conversion Factor Select
Screen (Figure 5-21) will appear.

5-12 SYSTEM INITIALIZATION November 07

CAPINTEC, INC. CAPTUS® 600

CONVERSION FACTORS 14:32

1. WELL
2. PROBE
3. VIEW/PRINT CONV FACTORS

0. RETURN TO PREVIOUS SCREEN

Figure 5-21

Press 3 to view and/or print the current Conversion Factors.
Select the appropriate detector by pressing 1 or 2.
Note: The Screen heading will say “CF FOR PROBE” or “CF FOR WELL” (Figure 5-22),

depending on the chosen detector.

Entering Nuclide Name

CF FOR WELL 13:06

NUCLIDE NAME: >

DONE OK

Figure 5-22

Type the one or two letter symbol for the nuclide. If this nuclide has just one letter, be sure to
press the SP (Space) key after the first letter. Then type the two or three numbers that
indicate the mass number for this nuclide.

Note: Use the “*” key to add the “m” for Metastable, if applicable.

The system is automatically in letter mode or number mode in the appropriate places.

November 07 SYSTEM INITIALIZATION 5-13

CAPINTEC, INC. CAPTUS® 600

For example, to enter Cobalt-57, input C, O, 5, 7 and ENTER; to enter Iodine-131, input I,
SP, 1, 3, 1 and ENTER.

Press F4 [OK] when the Nuclide Name is correct.

Press F1 [DONE] if all CFs have been input or measured.

Figure 5-23 will appear.

Note: If a CF for the chosen nuclide already exists, the current value will be displayed and
you will be asked if you would like to change it. If you respond that you would like to
change it, the system will proceed to Figure 5-23, otherwise you will return to Figure
5-22.

Selecting Measure or Input CF

CF FOR W ELL 13:06
NUCLIDE NAME: TC99M
MEASURE CF? (Y OR N)

Figure 5-23

Press Y (YES) to measure the CF.
Press N (NO) to input a CF.

Input CF
If INPUT CF was selected, the Input CF screen (Figure 5-24) will appear.

5-14 SYSTEM INITIALIZATION November 07

CAPINTEC, INC. CAPTUS® 600

CF FOR W ELL 13:06
NUCLIDE NAME: TC99m

INPUT CF: >

OK

Figure 5-24

Input the CF in units of dpm/cpm.

Press F4 [OK] when the value is correct. The Nuclide Name screen (Figure 5-23) will
re-appear.
Note: This must be a value that had been previously measured in the CAPTUS® 600

using the same detector and source configuration.

Measure CF
If MEASURE CF was selected, the CF Source Calibration Data screen (Figure 5-25)
will appear:

CF FOR W ELL 13:06

NUCLIDE NAME: TC99m

CALIB ACTIVITY: > μ Ci

CALIB DATE :

CALIB TIME : 12:00

C i/B q OK

Figure 5-25

Input the calibration activity, date and time. If it is a long-lived source, the time will not
be known and can be left as 12:00.

Press F1 [Ci/Bq] to switch between entering the activity in Ci to Bq and back. This
will not affect the unit used for anything else.

Press F4 [OK] when all entries are correct. Figure 5-26 will appear.

November 07 SYSTEM INITIALIZATION 5-15

CAPINTEC, INC. CAPTUS® 600

MEASURE TC99m SOURCE IN WELL
COUNTING PERIOD: >60 SEC

EXIT START
Figure 5-26

Input the counting time. The correct counting time depends upon the strength of the
source. Count long enough to obtain a good peak with good counting statistics.

Place the source in the correct position and press F4 [START].

Note: It is important that the source be in the same geometric relation to the detector
as the samples to be measured later. The Conversion Factors are only
applicable and accurate so long as the geometries are constant.

EXAMPLE:
• If you are measuring Conversion Factors for wipes to be done in the Well, the
calibrated source must be placed in the Well when measuring CF.

• If you are measuring Conversion Factors for Bioassay, the calibrated source
must be placed at the distance from the Probe that will be used for Bioassay
measurements.

The CAPTUS® 600 will begin counting on the appropriate gain range for the chosen
nuclide.

If the CAPTUS® 600 does not find a peak at the expected energy, the following
measurement error message will appear:

MEASUREMENT ERROR

Press Any Key to Continue

If this happens, press any key. Figure 5-26 will re-appear. Check the source. If the
source was correct and correctly positioned, the counting time may have been too
short to produce a detectable peak.

If the acquisition ended successfully, Figure 5-27 will appear.

5-16 SYSTEM INITIALIZATION November 07

CAPINTEC, INC. CAPTUS® 600

200 CTS FS

4335. cpm
OK?
(Y OR N)

200 keV

Figure 5-27

If the data is OK, press Y. You will then be asked to measure background.

After you accept the background, a summary screen (Figure 5-28) will appear. The
example is for a measurement of Co57.

CO57
NET: 4335. cpm

CALIB: 268.6kdpm
CURRENT: 5503 dpm

CF: 1.27

EXIT SAVE P
Figure 5-28

Press F4 [SAVE] to save the Conversion Factor.

Press PRINT [P] to print a report with the original calibration data, measured values
and calculated Conversion Factor.

Press F1 [EXIT] when finished.

Note: If F1 [EXIT] is pressed without first pressing F4 [SAVE], the Conversion
Factor will not be saved.

November 07 SYSTEM INITIALIZATION 5-17



CAPINTEC, INC. CAPTUS® 600

CHAPTER 6

ACCEPTANCE & QUALITY
ASSURANCE TESTS

To insure proper operation of the CAPTUS® 600, the following tests should be performed at
the indicated intervals.

ACCEPTANCE TESTS

The following tests must be performed in the following order before the initial use of the
CAPTUS® 600:

• Diagnostics
• Calibration Test
• Chi-Square Test
• Minimum Detectable Activity

QUALITY ASSURANCE TESTS

Daily Tests
The CAPTUS® 600 does not need to be calibrated every day, but its calibration needs to be
checked daily with the Calibration Test Procedure as described in the CALIBRATION TEST
section on page 6-2. When the Calibration Test function is performed daily, two things are
accomplished:

1. The fine gain of the multichannel analyzer is adjusted, eliminating the need to adjust
the High Voltage. This assures the unit is calibrated.

2. The Full Width-Half Maximum (FWHM) of the Cs137 peak is measured and recorded.
Automatic Regions of Interest (ROI) are calculated from the FWHM of the cesium
photopeak measured in test.

Monthly Tests

Perform an Auto Calibration Function as described in the AUTO CALIBRATION TEST
section on page 6-5. Perform a check on the system firmware functions by accessing the
Diagnostics module as described in the DIAGNOSTICS section on page 6-12. The
Diagnostics Module checks the RAM, PROM and EEPROM memory, and prints out stored
nuclide and standard source data for verification, and high voltage reference number and
gain adjustments.

November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-1

CAPINTEC, INC. CAPTUS® 600

Quarterly Tests

The Chi-Square Test, as described in the CHI-SQUARE TEST section on page 6-5, may be
performed every time Calibration Test is performed but should be performed at least
quarterly. The Chi-Square Test is performed by repeatedly measuring the Cs137 standard
using the region of interest determined in the test just performed. The measurements are
made for the number of repetitions entered in setup. However, the test can be performed for
a fewer number of repetitions by pressing [ABORT] during a measurement. In order to
calculate Chi-Square, at least 5 measurements should be made (but at least 10 is
recommended). When the test is finished, a report is printed (or displayed on the screen if
there is no printer).

The Minimum Detectable Activity (MDA) Test, as described in the MDA TEST section on
page 6-9, should be performed whenever the background activity changes (e.g. the unit is
moved to a new location or a new source of radiation is located nearby).

CALIBRATION TEST

To perform the CALIBRATION TEST, press the HOME key and then TEST key. The Test
menu (Figure 6-1) will appear.

14:32

1. CALIBRATION TEST
2. MDA TEST

0. RETURN TO SETUP MENU

Figure 6-1

Press 1 to select CALIBRATION TEST. The Well or Probe Selection Screen (Figure 6-2) will
appear.

6-2 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

TEST 14:32

1. WELL
2. PROBE

0. RETURN TO PREVIOUS SCREEN

Figure 6-2

To test the Well, press 1. To test the Probe, press 2.

Place the source in the correct geometry for the detector. (i.e., in the center of the Flat Probe;
on the face of the Drilled Probe; inside the well of the Well Probe). Even if there is only a
single detector, TEST must be performed for Probe and Well. Thus, the Probe and Well tests
may have different results even if there is only one detector.

When Well or Probe has been selected, the appropriate Test Screen will appear (Figure 6-3
or Figure 6-4). If an ID for the Cs137 source has been entered in the Cs137 Standard Setup
Function, the ID will appear on this screen.

PROBE TEST 14:32 WELL TEST 14:32

MEASURE CS137: CS1 MEASURE CS137:

START START
Figure 6-3 Figure 6-4

The rest of the Test procedure is the same for both the Probe and Well.

Press the F4 [START] key. The counting display (Figure 6-5) will appear. As the counts
increase, the vertical scale also increases, changing from 100, to 200, 500, etc. to
accommodate for the number of counts measured in the Cs137 standard source.

November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-3

CAPINTEC, INC. CAPTUS® 600
2000 Cts FS

ABORT 800

Figure 6-5

While adjusting the fine gain of the CAPTUS® 600 Pulse Height Analyzer (PHA), the unit
counts until the number of counts is sufficient for accurate calibration. Once the unit has
achieved a fine gain adjustment to within one channel, the unit will count until the number of
counts in the highest channel equals 1000 counts. The system uses the last peak measured
to calculate the energy resolution of the detector.

When the test is complete, Figure 6-6 will appear.

2000 Cts FS 165.1

800

Figure 6-6

Test will print the results automatically. If the printer is off-line, or there is no printer
connected to the CAPTUS® 600, a check printer message will appear on the screen and
prompt you to press any key to continue. If the printer is still off-line, or no printer is attached
to the system, the test data will be displayed on the screen.

The printout will show total counts in the ROI corresponding to the Cs137 peak or, if a
Conversion Factor has been stored for Cs137, activity will be printed.

If the Calibration Test fails, perform an Autocalibration function as described in the AUTO
CALIBRATION TEST section on page 6-5. Repeat the Calibration Test. If it fails another
time, contact Capintec’s Authorized Service Center for service.

6-4 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

CHI-SQUARE TEST

After the printout (or screen display) of the previous section is complete, you will be asked if
you want to perform a Chi-Square Test. If so, DO NOT REMOVE THE Cs137 STANDARD,
and press Y. The Chi-Square Test will be performed using the parameters entered in
CHAPTER 5: SYSTEM INITIALIZATION, SECTION: CHI-SQUARE TEST SETUP.

The report displays the counts for each repetition and then the calculated Chi-Square.

The Chi-Square is calculated from the following equation:

∑ ( )χ 2 = 1 n

x i=1
xi − x 2

where xi = counts for measurement i

x = average for the n measurements

Chi-Square values are given in the following table for 10, 15 and 20 measurements. The Chi-
Square value should fall between the 0.95 and 0.05 probability values in the table almost all
of the time. The more stringent 0.90 and 0.10 values are given for reference.

n = # of

measurements 0.95 0.90 0.10 0.05

10 3.33 4.17 14.7 16.9

15 6.57 7.79 21.1 23.7

20 10.1 11.7 27.2 30.1

Table 6-1

If the Chi-Square falls outside of this range, first repeat the test making sure that the
background and positioning are kept constant.

If the values are still out of range, contact Capintec’s Authorized Service Center for
assistance.

You always have the option of performing the Autocalibration Test, even when the Test
shows that calibration is within established limits.

AUTO CALIBRATION TEST

When the Test procedure indicates that the CAPTUS® 600 needs to be calibrated, you must
perform the AutoCal function.

November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-5

CAPINTEC, INC. CAPTUS® 600

The system also allows you to request the Auto Cal procedure, even when it is not indicated
by the Test function.

Press the HOME key, then the UTIL key. The main Utilities menu (Figure 6-7) will appear.

UTILITIES 14:32

1. MULTICHANNEL ANALYZER
2. STAFF BIO ASSAY RESULTS
3. SETUP
4. DIAGNOSTICS

0. RETURN TO PROBE SCREEN

Figure 6-7

Note: Selection 0 will display “RETURN TO WELL SCREEN” if the Utilities menu is
accessed from the Well Main Screen.

Press 3 to select SETUP. The message “PASSWORD:” will appear. Type the last three digits
of your CAPTUS® 600 serial number, and press the ENTER key. The Setup menu (Figure 6-
8) will appear.

SETUP 14:32

1. Ci/Bq
2. TEST DATA
3. THYROID UPTAKE
4. BIO ASSAY
5. AUTO CALIBRATION
6. ACTIVITY CONVERSION FACTORS
7. WIPE AND MCA SETUP
8. OTHER

0. RETURN TO UTILITIES MENU

Figure 6-8

Press 5 to select AUTO CALIBRATION. The Detector Select Screen (Figure 6-9) will appear.

6-6 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

CALIBRATION 14:32

1. WELL
2. PROBE

0. RETURN TO PREVIOUS SCREEN

Figure 6-9

Press 1 to select WELL or 2 to select PROBE. After making this selection, the appropriate
Calibration Screen will appear. Figure 6-10 is an example of the Probe Calibration Screen. If
data for a cesium standard was entered in the Cs137 Standard Setup, the source name will
appear on the display. Otherwise this field will be blank.

Note: Even if the CAPTUS® 600 is equipped with only one detector used for both Probe and
Well measurements, separate Auto Calibration must be done for the Well and Probe
in this section.

PROBE 14:32
C A L IB R A T IO N

MEASURE Cs137: CS1

START

Figure 6-10

Place the Cs137 standard source in the CAPTUS® 600 detector. Press the [F4] START key.

The counting display (Figure 6-11) will appear. As the counts increase, the vertical scale also
increases, changing from 100, to 200, 500, etc. to accommodate for the number of counts
measured by the CAPTUS® 600. The CAPTUS® 600 will count until sufficient counts are
accumulated for accurate calibration. After the AutoCal program sets the High Voltage, it
counts until the 662 keV gamma peak reaches 1000 counts. It then calculates the full width-
half maximum (FWHM) of the peak. This FWHM is used in calculating peak widths based on
the energy resolution of the detector. The system uses the FWHM calculated in AutoCal or
Test, whichever was done last.

November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-7

CAPINTEC, INC. CAPTUS® 600

The CAPTUS® 600 will repeatedly adjust the High Voltage to the detector until the Cs137
peak is adjusted to 662 ±8 keV. The counting period may repeat several times until the
system is calibrated.

2000 Cts FS dt: 4%

ABORT 800 keV

Figure 6-11

When the AutoCal procedure is completed, Figure 6-12 will appear and the system
automatically prints a calibration report.

2000 Cts FS 165.1 4.010keV/ch

800 keV

Figure 6-12

The screen then returns to the Setup menu.

Note: If the printer is off-line or if no printer is attached to the CAPTUS® 600, a check printer
message will appear on the screen at this point and prompt you to press any key to
continue. If a printer is attached to the unit check to be sure it is powered up, that it is
not out of paper, that the cable is connected, etc. When any key is pressed to
continue, if the printer is still off-line or if there is still no printer attached, the
calibration data will be displayed on the screen.

6-8 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

MDA TEST

This is a test of Minimum Detectable Activity for the specific nuclide selected by the user.
The test can be performed for the Probe or Well. A nuclide is chosen for the test (the default
is Tc99m) and the appropriate energy range (400 keV or 1600 keV) is automatically selected.
The test measures the background in the Region of Interest that would be used to measure
the activity of the selected nuclide.
The user also selects the counting period and the precision used in the calculation.
The minimum detectable counting rate is given by:

MDR = p * counts
T

where p is the precision, counts is the background counts in the channels for the nuclide, and
T is the counting time.
The precision can range from 1 to 9. The default value is 3.
To get the Minimum Detectable Activity, the minimum detectable counting rate is divided by
the efficiency for the nuclide:

MDA = MDR
Eff

To perform the MDA Test, press the HOME key and then TEST key. The Test menu (Figure
6-13) will appear.

14:32

1. CALIBRATION TEST
2. MDA TEST

0. RETURN TO SETUP MENU

Figure 6-13
Press 2 to select MDA TEST. The Well or Probe Selection Screen (Figure 6-14) will appear.

November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-9

CAPINTEC, INC. CAPTUS® 600

MDA TEST 14:32

1. WELL
2. PROBE

0. RETURN TO PREVIOUS SCREEN

Figure 6-14
To test the Well, press 1. To test the Probe, press 2.
After Well or Probe is chosen, the Nuclide Entry Screen (Figure 6-15) will appear.

MDA TEST 13:06
WELL

NUCLIDE NAME: >TC99M

DONE OK
Figure 6-15

If another nuclide is desired, type in the new nuclide name (use the * for the m in metastable
nuclides such as Tc99m).

Press F4 [OK] to continue with the MDA Test. Figure 6-16 will appear.

Press F1 [DONE] to abort the MDA Test.

6-10 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

MDA TEST 13:06
WELL

COUNTING PERIOD: >6O SEC

PRECISION : 3 ST. DEV.

PREC START
Figure 6-16

Input the desired counting period (60 sec is the minimum allowed).

Press F1 [PREC] to change the precision from 1 to 9 standard deviations (the default value
is 3).

When the desired counting period and precision have been entered, MAKE SURE THAT
THERE ARE NO SOURCES NEARBY and press F4 [START].

After the background has been counted, the Region of Interest corresponding to the selected
nuclide will be shaded and the counting rate in that ROI will be displayed for verification. If
the counting rate is OK, (i.e., there were counts but no source), press Y and ENTER.

A report with the selected nuclide, desired precision, Minimum Detectable Counting Rate and
Minimum Detectable Activity (if there is a Conversion Factor for the selected nuclide) will be
printed.

If the printer is off-line, or there is no printer connected to the CAPTUS® 600, a check printer
message will appear on the screen and prompt you to press any key to continue. If the
printer is still off-line, or no printer is attached to the system, the results will be displayed on
the screen.

November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-11

CAPINTEC, INC. CAPTUS® 600

DIAGNOSTICS

The CAPTUS® 600 has the ability to check system functions using a Diagnostics Utility.

To access the Diagnostics Utility, press the HOME key and then the UTIL key. The main
Utilities Menu (Figure 6-17) will appear.

UTILITIES 14:32

1. MULTI CHANNEL ANALYZER
2. STAFF BIO ASSAY RESULTS
3. SETUP
4. DIAGNOSTICS

0. RETURN TO PROBE SCREEN

Figure 6-17

Access the Diagnostics Utility by pressing 4. The Diagnostics Screen (Figure 6-18) will
appear.

D IA G N O S T IC S 14:32

Figure 6-18

If the printer is off-line, or there is no printer connected to the CAPTUS® 600, a check printer
message will appear on the screen and prompt you to press any key to continue. If your
printer is available, make sure it is connected, turned on and selected.

If the printer is on-line, a three page diagnostics report will be printed out while the screen in
Figure 6-18 is on the display. After the printing has stopped, the CAPTUS® 600 will begin

6-12 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

checking its system memory. A display similar to Figure 6-19 will appear (the PROM values
shown are just an example). The same results will also be sent to the printer.

D IA G N O S T IC S 14:32

RAM: PASS 7229 1EBE
3840 2D2C
PROM: PASS 7892 57F6
9B87
80EF
E710

EEPROM: PASS

Press any key to continue

Figure 6-19

If any of the test results indicate “FAIL” rather than “PASS”, it indicates a system malfunction.
If this happens, perform the Diagnostics Utility again. If the test(s) fail again, contact
Capintec’s Authorized Serve Center for assistance.

CAUTION!
Do NOT continue to use the CAPTUS® 600
if any Diagnostics test results read “FAIL”.

Diagnostics Printout
On the following pages is a sample Diagnostics printout. Below is a description of the
sections in the Diagnostics printout.

System Configuration
This data is entered into the system memory at the factory. It indicates to the
CAPTUS® 600 which detectors are connected on the back panel. The user cannot
change this.

Nuclide Data
Nuclides List
A listing of Nuclides in the CAPTUS® 600 memory. This list is entered at the factory.
Additional nuclides may be added to this list.

Half-Life
A listing of the Half-life for each nuclide in the CAPTUS® 600 memory.

Photon Energies
A listing of the Energy Photon Peaks used by the CAPTUS® 600 in the automatic
peak searching algorithm.

November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-13

CAPINTEC, INC. CAPTUS® 600

Conversion Factors
Conversion Factors that have been input or measured for each nuclide. Conversion
Factors may be different for Well or a Probe. Both Conversion Factors are printed.

Additional Nuclides
A listing of nuclide data for any additional nuclides that have been entered.

User Keys
A listing of nuclides assigned to the USER keys.

Standard Source
A listing of calibration date, calibration activity and current activity of the Standard
Cs137 sources that have been entered in the CAPTUS® 600 memory.

HV Reference (Probe and Well)
A listing of the High Voltage Reference set during the Autocalibration Test. These
values will vary between 0 and 255.

Fine Gain Adjustment (Probe and Well)
A listing of the Fine Adjustment set during Calibration Test. These values will vary
between 0 and 255.

PROM Values
These diagnostic values uniquely determine the software revision level. If the system
reads these values incorrectly, the PROM test will fail.

Memory Tests
The results of the RAM, PROM, and EEPROM tests. If the PROM test fails, the
PROM values will be printed. Any test that fails indicates a system malfunction and
warrants a call to Capintec’s Authorized Service Center.

6-14 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

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November 07 ACCEPTANCE & QUALITY ASSURANCE TESTS 6-15

CAPINTEC, INC. CAPTUS® 600

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6-16 ACCEPTANCE & QUALITY ASSURANCE TESTS November 07

CAPINTEC, INC. CAPTUS® 600

CHAPTER 7

THYROID UPTAKE SETUP

COUNTING METHODS

Counting Methods refer to the Counting Time Base and Regions of Interest for each nuclide.
The values are the same for all entered protocols.

The CAPTUS® 600 offers two counting time bases: REAL time and LIVE time. The
Multichannel Analyzer (MCA) in the CAPTUS® 600 measures each pulse that comes out of
the Sodium Iodide/Photomultiplier tube detector. To process each pulse requires a finite
amount of time. During the time the MCA is busy, it cannot accept another pulse. Any other
pulse that occurs during this time is not measured, and is lost. During this time, the MCA is
said to be DEAD.

Live Time is defined as the time during which the MCA can actually accept and process a
pulse.

Real Time is defined as the actual clock interval.

If LIVE time is chosen, the CAPTUS® 600 counts until the MCA's Live Time reaches the
specified counting period. The actual counting time is always greater than or equal to the
requested Live Time.

If REAL time is chosen, the CAPTUS® 600 counts until the Real Time reaches the specified
count period. The count rate is calculated from measured Live Time.

To view or change the Counting Method, press the HOME key, then the UTIL key. The main
Utilities menu (Figure 7-1) will appear.

UTILITIES 14:32

1. MULTICHANNEL ANALYZER
2. STAFF BIO ASSAY RESULTS
3. SETUP
4. DIAGNOSTICS

0. RETURN TO PROBE SCREEN

Figure 7-1

November 07 THYROID UPTAKE SETUP 7-1

CAPINTEC, INC. CAPTUS® 600

Note: Selection 0 will display “RETURN TO WELL SCREEN” if the Utilities menu is
accessed from the Well main screen.

Press 3 to select SETUP. The message “PASSWORD:” will appear. Type the last three digits
of your CAPTUS® 600 serial number, and press the ENTER key. The Setup menu (Figure 7-
2) will appear.

SETUP 14:32

1. Ci/Bq
2. TEST DATA
3. THYROID UPTAKE
4. BIO ASSAY
5. AUTO CALIBRATION
6. ACTIVITY CONVERSION FACTORS
7. WIPE AND MCA SETUP
8. OTHER

0. RETURN TO UTILITIES MENU

Figure 7-2

Press 3 to select THYROID UPTAKE. The Thyroid Uptake Setup menu (Figure 7-3) will
appear:

THYROID UPTAKE SETUP 14:32

1. COUNTING
2. PROTOCOLS
3. PRINT ALL

0. RETURN TO SETUP MENU

Figure 7-3

Press 1 to select COUNTING. Figure 7-4 will appear.

Note: If there are active Thyroid Patients or an active standard, a message will appear
informing you that Counting Method cannot be changed. This is to avoid changing
counting methods in the middle of a study and getting erroneous results. If you want
to see the current values, press 3 to print all the Protocols and the current Counting
Methods.

7-2 THYROID UPTAKE SETUP November 07

CAPINTEC, INC. CAPTUS® 600

THYROID UPTAKE SETUP 14:32

COUNTING TIME BASE: LIVE

Counting stops when the measured Live
Time reaches the specified counting
period

BASE OK

Figure 7-4

The F1 [BASE] key is a toggle switch that changes the Counting Time Base between two
choices: LIVE and REAL. When the F1 [BASE] key is pressed to select REAL time, the
screen changes to Figure 7-5.

THYROID UPTAKE SETUP 14:32

COUNTING TIME BASE: REAL
Count for Specified Real Time --
Counting rate is calculated from
measured Live Time

BASE OK

Figure 7-5

When the information on the screen is correct, press the F4 [OK] key. The screen will
change to the Region Of Interest Screen (Figure 7-6).

THYROID UPTAKE SETUP 14:32
I 123

REGION OF INTEREST:
> 20% TO LEFT
20% TO RIGHT

OF FULL ENERGY PEAK

OK

Figure 7-6

November 07 THYROID UPTAKE SETUP 7-3

CAPINTEC, INC. CAPTUS® 600

The Region Of Interest Screen will be displayed for each nuclide.

The default values are 20% to the left and 20% to the right for all the nuclides.

The range limits are:

I123: from 10% to 40%
TO LEFT: from 10% to 25%
TO RIGHT:

I131: from 10% to 60%
TO LEFT: from 10% to 25%
TO RIGHT:

Tc99m: from 10% to 40%
TO LEFT: from 10% to 25%
TO RIGHT:

When the displayed information is correct, press the F4 [OK] key.

PROTOCOLS

A Thyroid Uptake study cannot be done without a protocol. No protocols come with the
CAPTUS® 600 – they are always entered by the user. When patient data is entered, a screen
listing the protocols is displayed if more than one protocol has been entered.

To change or enter Protocols, press the HOME key, then the UTIL key. The main Utilities
menu (Figure 7-7) will appear.

UTILITIES 14:32

1. MULTICHANNEL ANALYZER
2. STAFF BIO ASSAY RESULTS
3. SETUP
4. DIAGNOSTICS

0. RETURN TO PROBE SCREEN

Figure 7-7

Note: Selection 0 will display “RETURN TO WELL SCREEN” if the Utilities menu is
accessed from the Well main screen.

7-4 THYROID UPTAKE SETUP November 07

CAPINTEC, INC. CAPTUS® 600

Press 3 to select SETUP. The message “PASSWORD:” will appear. Type the last three digits
of your CAPTUS® 600 serial number, and press the ENTER key. The Setup menu (Figure 7-

8) will appear.

SETUP 14:32

1. Ci/Bq
2. TEST DATA
3. THYROID UPTAKE
4. BIO ASSAY
5. AUTO CALIBRATION
6. ACTIVITY CONVERSION FACTORS
7. WIPE AND MCA SETUP
8. OTHER

0. RETURN TO UTILITIES MENU

Figure 7-8

Press 3 to select THYROID UPTAKE. The Thyroid Uptake Setup menu (Figure 7-9) will
appear:

THYROID UPTAKE SETUP 14:32

1. COUNTING
2. PROTOCOLS
3. PRINT ALL

0. RETURN TO SETUP MENU

Figure 7-9

Press 2 to select PROTOCOLS. The Protocol List Screen (Figure 7-10) will appear.
If no protocols have been stored in the CAPTUS® 600, the list part of the screen is blank. All
function keys except for F1 [ADD] and F4 [DONE] are also blank as shown in Figure 7-11.

November 07 THYROID UPTAKE SETUP 7-5

CAPINTEC, INC. CAPTUS® 600
TU PROTOCOLS 14:32
TU PROTOCOLS 14:32

> MAIN PROTOCOL
2ND PROTOCOL
PROTOCOL I131

ADD EDIT DEL DONE P ADD DONE
Figure 7-10 Figure 7-11

Adding a Protocol
Press the F1 [ADD] key.
Note: If 4 protocols are already stored in the CAPTUS® 600, the following message will

appear:

NO ROOM FOR MORE PROTOCOLS

Press Any Key to Continue

A protocol will have to be deleted to make another entry.

While entering data for a protocol, the BSP key can be used to go back any number of
screens to review or change entries.

When the F1 [ADD] key is pressed, the Protocol Name Screen (Figure 7-12) will appear.

TU PROTOCOLS 14:32

NAME: >

NUM OK

Figure 7-12
The protocol name can consist of up to 20 characters, letters and/or numbers.

7-6 THYROID UPTAKE SETUP November 07

CAPINTEC, INC. CAPTUS® 600

Press F1 [NUM] to switch to numeric input and display “LET”.

Press F1 [LET] to switch back to letter input and display “NUM”.

When the protocol name is correct, press F4 [OK]. The Calculation Method Screen (Figure
7-13) will appear.

TU PROTOCOLS 14:32

NAME: PROT 1
CALCULATION: ONE CAPSULE

TU Calculation may be:

One Capsule
Standard
Two Capsules

METH OK

Figure 7-13

Press F1 [METH] to change the Calculation method from “ONE CAPSULE” to “STANDARD”
to “TWO CAPSULES”.

Refer to the CHAPTER 2: FUNCTIONAL & TECHICAL DESCRIPTION; SECTION:
THYROID UPTAKE PROTOCOLS for a description of the three methods.

When the desired calculation method is displayed, press F4 [OK]. Figure 7-14 will appear.

TU PROTOCOLS 14:32

NAME: PROT 1
CALCULATION: ONE CAPSULE

NUCLIDE: I 131
NUMBER OF UPTAKES: 1
COUNTING REPETITIONS: 2
NUCLD NUMBR REPS OK

Figure 7-14

This screen is used to select the nuclide, number of uptakes and number of counting
repetitions:

November 07 THYROID UPTAKE SETUP 7-7

CAPINTEC, INC. CAPTUS® 600

Press F1 [NUCLD] to select the nuclide. The nuclide will cycle from “I131” to “Tc99m” to
“I123” and back to “I131”.

Press F2 [NUMBR] to select the number of uptakes in the study. The choices are “1”, “2”, “3”
or "4”.

Note: It's better to have too many measurements than too few measurements in a protocol.
If the physician decides, for example, that a patient does not need a third or fourth
measurement, the study can still be completed on the CAPTUS® 600 without any
problem. But if the patient is assigned to a protocol that only has two measurements,
and then the physician decides that the patient needs a third measurement, there's
no way to add another measurement for this patient in the CAPTUS® 600 system. If
you encounter that type of problem, the best solution is to make a printout of all
patient data, and then change the last measurement of the protocol to obtain results
of the additional measurement.

Press F3 [REPS] to select the number of repetitions for each measurement. The choices are
“1” or “2”.

Note: If 2 repetitions are chosen, it is still possible to perform the measurement without
making the second repetition.

When all entries are correct, press F4 [OK]. Figure 7-15 will appear allowing the Pre-Dose
Measurement option and Counting Period to be set.

TU PROTOCOLS 14:32

NAME: PROT 1
CALCULATION: ONE CAPSULE

COUNTING PERIOD :> 120 SEC
PRE-DOSE MEASUREMENT: NO

PRE OK
Figure 7-15

Input the desired Counting Period. The minimum is 10 seconds and the maximum is 9999
seconds.

Press F1 [PRE] to select the Pre-Dose Measurement option. This key toggles between “NO”
and “YES”. The default is No.

When all entries are correct, press F4 [OK].

7-8 THYROID UPTAKE SETUP November 07

CAPINTEC, INC. CAPTUS® 600

If the Calculation Method is One Capsule or Two Capsules, the Multi-Capsules option is now
chosen as shown in Figure 7-16.

TU PROTOCOLS 14:32

NAME: PROT 1
CALCULATION: ONE CAPSULE

MULTI-CAPSULES: NO

MULT OK
Figure 7-16

Press F1 [MULT] to switch from “NO” to “ONE” to “EACH” to “ALL”.

Refer to the CHAPTER 2: FUNCTIONAL & TECHICAL DESCRIPTION; SECTION THYROID
UPTAKE PROTOCOLS for a description of Multi-Capsules.

When the correct option is displayed, press F4 [OK].

The Measurement Times and Normal Value Range can now be input (Figure 7-17) for each
uptake.

TU PROTOCOLS 14:32

NAME: PROT 1
CALCULATION: ONE CAPSULE

UPTAKE NUMBER: 1 / 4

MEASURE AT :>2 HOURS

MINIMUM NORMAL VALUE : 0 %

MAXIMUM NORMAL VALUE : 99 %

OK

Figure 7-17

The Uptake Number indicates which uptake the data is for and the number of uptakes that
have been chosen for the study. In the example, this is the first of 4 uptakes.

At the “MEASURE AT” prompt, input the number of hours between dose administration and
this uptake measurement.

November 07 THYROID UPTAKE SETUP 7-9

CAPINTEC, INC. CAPTUS® 600

Note: This is only the expected time of the uptake measurement for this protocol. The
actual time the study is performed will determine how results are calculated. The
actual time will appear on all reports.

The CAPTUS® 600 printout can indicate whether uptake measurements are within a normal
range, which is determined by the next two fields, “MINIMUM NORMAL VALUE:” and
“MAXIMUM NORMAL VALUE:”. If you want to establish a normal range for this
measurement, input the minimum and maximum boundaries in these fields. If you do not
need to determine a normal range, leave these fields at the default values of 0% and 99%.
This normal range is defined by markers on the graph in the results report. They do not in
any way define normal values in a diagnostic sense. Each facility must establish these
values. The actual uptake results are the data to check when reading reports.

Press F4 [OK] when all entries are correct.

If more than one measurement was selected for this protocol, the next screen is the same as
Figure 7-17, except that the “UPTAKE NUMBER:” line has changed from 1 / 4 to 2 / 4.

Continue inputting information in this parameter screen until you finish the last Uptake
Number for this protocol.

After all the data has been entered, the protocol may be printed and/or saved (Figure 7-18).

TU PROTOCOLS 14:32

NAME: PROT 1
CALCULATION: ONE CAPSULE

DONE P

Figure 7-18

Press PRINT [P] to obtain a printout of the protocol.
Press F4 [DONE] to save the protocol to memory and return to the Protocol List Screen
(Figure 7-10) with the new protocol added to the list.

7-10 THYROID UPTAKE SETUP November 07

CAPINTEC, INC. CAPTUS® 600

Editing a Protocol
A protocol may be changed (edited) when it is not in use. If there is an active patient with the
selected protocol, a message will appear and you will only be allowed to view the protocol,
not edit it.

When the Protocol List Screen (Figure 7-10) appears, use the ARROW keys to position the
prompt in front of the protocol to be edited (or viewed) and press F2 [EDIT].

All the screens described in the Adding a Protocol section on page 7-6 will appear with the
current values displayed.

Deleting a Protocol
When the Protocol List Screen (Figure 7-10) appears, use the ARROW keys to position the
prompt in front of the protocol to be deleted and press F3 [DEL].

Note: The CAPTUS® 600 will not allow you to delete a protocol that is assigned to an active
patient. You must complete the patient study and/or delete the patient data before
deleting a protocol.

The name of the protocol will be displayed and you will be asked if you want to delete it.

Press Y to delete the protocol. The screen returns to the Protocol List Screen (Figure 7-10)
with that protocol deleted from the list.

Press N if the wrong protocol was selected. The screen returns to the Protocol List Screen
(Figure 7-10) unchanged.

Printing Protocol Information
A printout of all the protocols can be obtained by pressing PRINT [P] on the Protocol List
Screen (Figure 7-10).

An alternative way to print all protocol information is to select choice 3 from the Thyroid
Uptake Setup menu (Figure 7-9). This can be used even if there are no protocols; in that
case the Counting Methods will be printed.

November 07 THYROID UPTAKE SETUP 7-11



CAPINTEC, INC. CAPTUS® 600

CHAPTER 8

THYROID UPTAKE GENERAL
INSTRUCTIONS

The instructions in this section pertain to all of the Calculation Methods. Further instructions
for each method are in separate sections.

The section describes:
• Accessing Thyroid Uptake Studies,
• Entering Patient Demographics,
• Selecting Protocol,
• Selecting Patient,
• Printing TU Patient Summary,
• Viewing Results,
• Selecting Patient To Measure,
• Measuring The Neck And Thigh,
• Pre-Dose Measurement, and
• Printing Results

ACCESSING THYROID UPTAKE STUDIES

Press the HOME key and the PROBE key to display the main Probe Screen (Figure 8-1).

PROBE 14:32

F1 F2 F3 F4
T/U STAND B IO

Figure 8-1

November 07 THYROID UPTAKE GENERAL INSTRUCTIONS 8-1

CAPINTEC, INC. CAPTUS® 600

Press F1 [T/U]. The Thyroid Uptake Patient Selection Screen (Figure 8-2 or Figure 8-3) will
appear. If no patients have been entered, the list is blank and only the F1 [NEW] key is
displayed.

THYROID UPTAKE 14:32 THYROID UPTAKE 14:32

>KETCHUM, LIN
MONROE, MAR

NEW DEL VIEW MEAS P NEW
Figure 8-2
Figure 8-3

ENTERING PATIENT DEMOGRAPHICS

Press F1 [NEW] to add a Thyroid Uptake patient. The Patient Data Screen (Figure 8-4) will
appear.

TH Y R O ID U P TA K E 14:32

P A TIE N T N A M E

LA S T :>

FIR S T :

ID # :
DOB :
PHYS :

SEX : F

SEX OK

Figure 8-4

The maximum number of Thyroid Uptake patients is 15. If 15 Thyroid Uptake patients have
already been entered, a message will appear. Delete any patients whose studies have been
completed as described in the VIEWING PATIENT INFORMATION section on page 8-5.

Input data in all the fields. The “DOB” (Date of Birth) field is optional. The “SEX” field is
toggled between “M” and “F” by pressing the F1 [SEX] key.

When the data is correct, press the OK [F4] key. The system will return to the Patient
Selection Screen (Figure 8-2) with the new patient entered into the list.

8-2 THYROID UPTAKE GENERAL INSTRUCTIONS November 07

CAPINTEC, INC. CAPTUS® 600

To exit from the Patient Selection Screen, press BSP or HOME to return to the main Probe
Screen (Figure 8-1).

SELECTING PROTOCOL

If more than one protocol has been entered, the Select Protocol Screen (Figure 8-5) will
appear.

THYROID UPTAKE 14:32
SELECT PROTOCOL

> PROT 1
PROT 2
PROT 3

Figure 8-5

Use the ARROW keys to position the cursor next to the protocol to be assigned to this
patient, and press the ENTER key. The Protocol Summary Screen (Figure 8-6) will appear.

KETCHUM, LIN
PROTOCOL: PROT 1
CALCULATION: ONE CAPSULE
NUCLIDE: I 131
UPTAKES AT: 2 4 24 48 HOURS
COUNTING REPETITIONS: 2
COUNTING PERIOD : 60 SEC
OK? (Y OR N)

Figure 8-6

On this screen, the patient name consists of the entire last name and the first three letters of
the first name.

November 07 THYROID UPTAKE GENERAL INSTRUCTIONS 8-3

CAPINTEC, INC. CAPTUS® 600

If the Thyroid Uptake Protocol Information, displayed in Figure 8-6, is not correct, press the N
key, to answer “NO”, then press the ENTER key. The Select Protocol Screen (Figure 8-5) will
re-appear.

Once the patient information is entered it can still be changed. Refer to the VIEWING
PATIENT INFORMATION section on page 8-5 for instructions.

The subsequent screens depend on which method has been chosen for this patient's Thyroid
Uptake protocol and will be discussed separately.

SELECTING PATIENT

When administered data has been entered for a patient, the measurement hours, day and
time for the first 2 uptakes (only 1 if the protocol only called for 1 uptake) is displayed. In the
following example, the protocol calls for a measurement at 2, 4 and 24 hours and the dose
was administered at 11:49 on a Tuesday.

THYROID UPTAKE 13:11

>SMITH, JOH 2 TU 13:49

4 TU 15:49

NEW DEL VIEW MEAS P

Figure 8-7

After the first measurement has been made, the result of the uptake will be displayed as
shown in Figure 8-8.

THYROID UPTAKE 13:11

>SMITH, JOH 2 24%

4 TU 15:49

NEW DEL VIEW MEAS P
Figure 8-8

8-4 THYROID UPTAKE GENERAL INSTRUCTIONS November 07

CAPINTEC, INC. CAPTUS® 600

After the second measurement has been made, the result of the second uptake and the time
for the next uptake will be displayed as shown in Figure 8-9.

THYROID UPTAKE 13:11

>SMITH, JOH 4 30%

24 WE 11:49

NEW DEL VIEW MEAS P
Figure 8-9

After the third (last) measurement is made, the results of the last 2 measurements will be
displayed.

PRINTING THYROID UPTAKE PATIENT SUMMARY

To obtain a summary of the results for all the Thyroid Uptake patients, press PRINT [P] on
the Patient Selection Screen (Figure 8-2).

VIEWING PATIENT INFORMATION

To view or print details of the results for a patient or to edit or delete a selected patient’s
data, use the ARROW keys to position the cursor next to the patient, and press the F3
[VIEW] key.

A summary of the patient’s results and scheduling will appear (the example (Figure 8-10) is
for One Capsule Method after the first uptake).

November 07 THYROID UPTAKE GENERAL INSTRUCTIONS 8-5

CAPINTEC, INC. CAPTUS® 600

THYROID UPTAKE 14:32

DASILVA, AND
PROTOCOL: 1 CAPSULE

CAPSULE : TU 11:09 250.0 μ Ci
UPTAKE 1: 24%
UPTAKE 2: TU 15:09

GRAPH DEL EDIT MEAS P

Figure 8-10

Press F3 [EDIT] to edit patient data.

Press F2 [DEL] to delete patient data

Press F1 [GRAPH] to view the graphic display as shown in Figure 8-20. Printing can be
done from that display.

Press F4 [MEAS] to make a measurement. The function keys disappear and the prompt
appears at the measurement to be performed.

Press PRINT [P] to print the complete Thyroid Uptake report.

SELECTING PATIENT TO MEASURE

When it is time to perform an uptake, the patient and measurement can be selected from
either the Patient Selection Screen (Figure 8-2) or the View Screen (Figure 8-10) described
above by pressing F4 [MEAS]. The Measurement Summary Screen (Figure 8-11) will appear
with the prompt at the measurement to be performed next:

THYROID UPTAKE 14:32

DASILVA, AND
PROTOCOL: 1 CAPSULE

CAPSULE : TU 11:09 250.0 μ Ci
UPTAKE 1: 24%

> UPTAKE 2: TU 15:09

Figure 8-11

8-6 THYROID UPTAKE GENERAL INSTRUCTIONS November 07

CAPINTEC, INC. CAPTUS® 600

If the prompt is not at the first uptake, the previous uptake can be re-measured.

If the “ONE CAPSULE” method has been chosen and the capsule has been measured but
not administered, it can be re-measured.

Use the ARROW keys to move the prompt to the correct line if necessary.

Press ENTER to begin the measurement.

If all the scheduled measurements have been made, Figure 8-12 will appear.

THYROID UPTAKE 14:32

DASILVA, AND
PROTOCOL: 1 CAPSULE

CAPSULE : TU 11:09 250.0 μ Ci
UPTAKE 1: 24%

UPTAKE 2: 30%
> REVIEW RESULTS

MEASUREMENT FINISHED

Figure 8-12

Pressing ENTER with the prompt at “REVIEW RESULTS” will bring up the Graphic Display
Screen (Figure 8-14) described below.

MEASURING THE NECK AND THIGH

The main part of the Thyroid Uptake Study is measuring the patient’s neck and thigh. This is
the same for all Calculation Methods.

The measurement begins by prompting the user to measure the neck at the distance
previously chosen as shown in Figure 8-13.

November 07 THYROID UPTAKE GENERAL INSTRUCTIONS 8-7

CAPINTEC, INC. CAPTUS® 600

THYROID UPTAKE 14:32

DASILVA, AND
PROTOCOL: 1 CAPSULE

MEASURE NECK
AT: 25 CM

COUNTING REPETITION # 1 / 2

EXIT START

Figure 8-13

Note: Figure 8-13 calls for “COUNTING REPETITION #1”. Some protocols call for
repetitions of each measurement so that results can be averaged. In such protocols,
all measurements except room background counts are repeated.

Position the Probe over the thyroid gland at the distance shown on the screen and press the
F4 [START] key.

A graph that plots total counts (vertical axis) versus energy levels (horizontal axis) appears
on the screen (Figure 8-14). The energy scale is marked on the horizontal axis and depends
on the nuclide. The counting period set up in the protocol appears to the right of the graph (in
this example, 60 seconds). The counts per minute value and the plotted points on the graph
are updated each second. (If Live Time was chosen as the Counting Time Base instead of
Real Time, the counting period does not appear on the screen.)

When the counting period is finished, Figure 8-15 will appear.

100 dt: 3% 100

5111 cpm 50sec 6557 cpm

OK?
(Y OR N)

ABORT NECK 400 keV NECK 400 keV

Figure 8-14 Figure 8-15

If the final count value does not appear to be correct, press N and ENTER. The system will
return to Figure 8-13 so that the measurement can be performed again.

8-8 THYROID UPTAKE GENERAL INSTRUCTIONS November 07

CAPINTEC, INC. CAPTUS® 600

If the final count value does appear to be correct, press Y and ENTER. The Measure Thigh
Screen (Figure 8-16) will appear.

THYROID UPTAKE 14:32

DASILVA, AND
PROTOCOL: 1 CAPSULE

MEASURE THIGH

AT: 25 CM

COUNTING REPETITION # 1 / 2

EXIT START

Figure 8-16

If the protocol selected calls for more than one repetition, the system performs another
acquisition. Re-position the Probe for each repetition. The system will return to Figure 8-13
for each repetition of the Neck measurement.

If the second repetition is not desired, press F2 [ABORT] during the count and the
measurement will not be used.

Position the probe at the patient's thigh and press the F4 [START] key.

The next two screens that will appear on the display are exactly like Figure 8-14 and Figure
8-15, and they function with the same directions given above for those screens.

PRE-DOSE MEASUREMENT

If the protocol indicates that a Pre-Dose Measurement is to be performed, the Pre-Dose
Screen (Figure 8-17) will appear.

THYROID UPTAKE 14:32

PRE-DOSE MEASUREMENT: MEAS

SKIP OK
Figure 8-17

November 07 THYROID UPTAKE GENERAL INSTRUCTIONS 8-9

CAPINTEC, INC. CAPTUS® 600

Press F1 [SKIP] to skip the measurement (i.e. perform it later if possible or choose not to
perform it). Figure 8-18 will appear.

THYROID UPTAKE 14:32

PRE-DOSE MEASUREMENT: SKIP

MEAS OK
Figure 8-18

Press F4 [OK] to accept the displayed choice. If OK is pressed while “SKIP” is displayed,
you will be asked to verify that you want to skip the Pre-Dose Measurement.

Press BSP to exit the screen without making a choice and ending the current procedure.

If Pre-Dose Measurement is chosen, the Measure Neck Screen (Figure 8-19) will appear.

THYROID UPTAKE 14:32

DASILVA, AND
PROTOCOL: 1 CAPSULE

MEASURE NECK

AT: > 25 CM

COUNTING REPETITION # 1 / 2

EXIT START

Figure 8-19

If the Thyroid Uptake method is “ONE CAPSULE” or “TWO CAPSULES”, the displayed “AT:”
distance of 25cm is the default value of the Probe’s position away from the patient's neck. If
this is not the value to be used for the Thyroid Uptake study, input the correct value. This
value will be used throughout the study and cannot be changed.

If the Thyroid Uptake method is “STANDARD CAPSULE”, the displayed “AT:” distance is the
distance chosen when the Standard Capsule was first measured.

8-10 THYROID UPTAKE GENERAL INSTRUCTIONS November 07