How To Choose The Best ADC Linker
The development of antibody-drug conjugates (ADCs) has significantly been advanced in the past decade due to improvements in payloads, linkers and conjugation methods. In particular, the linker design plays a key role in regulating the stability of ADC in the systemic circulation and the efficiency of payload release in tumors, thereby affecting the pharmacokinetics (PK), efficacy and toxicity characteristics of ADC.
-
Follow
-
0
-
Embed
-
Share
-
Upload
