TPW July-August 2022

CONTENTS

News Face to Face Technology 82

New Arrivals 4, DGDA News 21, News 22, Ahmed Kamrul Alam 36 Innovation 83
FIP News 28, Seminar 29, Spotlight 30
Article Worth Knowing About 85

Dr. Md. Akter Hossain (M. Pharm, PhD) 51 Facts on Finger Tips 86

Interview Glossary of Dermatology Term 86

Prof. Dr. M. U. Kabir Chowdhury 33 AMR 39 Skin Health 87

Prof. Dr. M.N. Huda 35 Pharmacovigilance 50 Research Update 88

Prof. Dr. Md. Qamrul Hassan Jaigirdar 41 Gleanings From Local Press 60 Health Tips 91

Prof. Dr. Rashed Mohammad Khan 45 Dermatology Quiz 70 FDA Update 92

Prof. Dr. M Mujibul Hoque 47 Dermatology update 71 FDA Approval 93

Prof. Dr. Md. Siraj Uddin 57 What’s New 75

Prof. Dr. Masuda Khatun 63 Conference 94

Professor Mohammad Samiul Huq 65 Did You Know 79 Appointments And Promotions 95

Dr. SM Bakhtiar Kamal 73 Drug Safety 80 Registration Rules 96

Dr. Mahmud Chowdhury 77 Red Alert 81 Upcoming Event 99

National Prof. Brig. (Rtd.) Abdul Malik board of Advisors Prof. Dr. ABM Abdullah
Founder & President UGC Professor, BSMMU
National Heart Foundation, Dhaka Prof. Dr. TA Chowdhury Personal Physician to Hon’ble Prime Minister
Professor, Dept. of Obstetrics & Gynaecology
National Prof. Dr. A K Azad Khan BIRDEM, Dhaka Prof. Dr. Mohammod Shahidullah
President Department of Neonatology
Diabetic Association of Bangladesh & Prof. Dr. Abdul Ghani BSMMU, Dhaka
Chairman Board of Trustees Ex-Chairman
Bangladesh University of Health Dept. of Pharmacy, University of Dhaka Prof. M.A. Salam
Sciences (BUHS), Dhaka Founder President & CEO
Prof. Dr. Harun-Ur-Rashid Urology & Transplant Foundation of Bangladesh
Advisor, International Affairs Founder & Chief Consultant Dhaka
Prof. Dr. Moshe Szyf Kidney Fundation Hospital &
GlaxoSmithKline & James McGill Professor Research Institute, Dhaka head of marketing
Dept. of Pharmacology & Therapeutics Faisal Ahmmed
McGill University Medical School Editor Marketing
Montreal, Quebec Canada Muhammad Masud Md. Shohag Hossen
Pharmaceutical Advisor Executive Editor Circulation
Abu Nayeem Saifur Rahman S A Nadeem Md. Sikander
Medical Advisor managing editor Md. Bashar
Dr. R. M. Samiul Hasan Sandip Kumar Saha Computer Graphics
Media Advisor Associate Editor Md. Aftabul Islam
Dr. Sajal Ashfaque Humayera Kabir Hana Production
Dr. SMG Saklayen Russel Business Editor Mati Ar Manush
Dr. Saleh Mahmood Tusher Md. Shahjahan Editorial/Business Office
Research Editor 51, Kalabagan 1st Lane (Ground floor)
Prof. Dr. Md. Moklesur Rahman Sarker Dhaka-1205, Bangladesh
graphics Designer E-mail: [email protected]
Munir Hussein

Volume 13 n No. 3 n july-august 2022 Published by Muhammad Masud. 51, Kalabagan 1st Lane (Ground floor) Dhaka-1205,
Bangladesh, Tel/Fax: +88 02 58155677 n Printing: Image Printing & Packaging
3 Purana Paltan, Dhaka.

IMPORTANT: Every care is taken to ensure the accuracy of the information given in
this journal but no responsibility is accepted for any error and/or omissions. Editor/
publisher is not responsible in any way for views/comments expressed herein.



NEW ARRIVALS Acme

Brand Name: Bilan Kids Brand Name: Bilan
Generic Name: Bilastine INN Generic Name: Bilastine INN
Strength: 10 mg Strength: 2.5 mg/ml (50 ml)
Dosage Form: Orally Dosage Form: Oral Solution
Disintegrating Tablet (ODT) Indications: Allergic rhinitis,
Indications: Allergic rhinitis, rhinoconjunctivitis and
rhinoconjunctivitis and urticaria
urticaria.
Brand Name: Lino-M 1000
Brand Name: Hemorise Generic Name: Linagliptin
Generic Name: Ferric INN + Metformin BP
Carboxymaltose INN Strength: 2.5 mg + 1000 mg
Strength: 100 mg/2 ml, 500 Dosage Form: Tablet
mg/10 ml & 1000 mg/20 ml Indications: Type 2 Diabetes
Dosage Form: Injection Mellitus.
Indications: Iron deficiency
anemia.

Aristopharma

Brand Name: Limpa
Generic Name: Linagliptin + Empagliflozin
Strength: 5 mg+10 mg, 5 mg+25 mg
Dosage Form: Tablet
Indications: Type-2 diabetes mellitus.

Beximco

Brand Name: Onriva® Trio Bexicap® Brand Name:  Vivori®
Generic Name: Indacaterol + Generic Name: Voriconazole
Glycopyrronium + Mometasone Furoate Strength: 200 mg and 50 mg Tablets
Strength: 150 µg + 50 µg + 160 µg Dosage Form:  Tablet
Dosage Form:  Dry Powder Inhaler (DPI) Indications:  l Invasive aspergillosis
Indications: Long-term once-daily l Candidemia (nonneutropenics) and
maintenance treatment of asthma disseminated candidiasis in skin,
in adult patients not adequately abdomen, kidney, bladder wall, and
controlled with a maintenance wounds l Esophageal candidiasis
combination of a long-acting beta2- l Serious infections caused by
agonist and a high dose of an inhaled Scedosporium piospermum and
corticosteroid who experienced one Fusarium species including Fusarium
or more asthma exacerbations in the solani, in patients intolerant of, or
previous year. refractory to, other therapy.

6 THE PHARMA WORLD

Biopharma

Brand Name:  Kaneva® Brand Name: Mexclav Brand Name: Listarin Brand Name: Rixoban
Generic Name:  Erlotinib Generic Name: Cefuroxime Generic Name: Eucalyptol Generic Name:
Strength: 150 mg + Clavulanic Acid + Methyl salicylate + Rivaroxaban
Dosage Form: Tablet Strength: (Cefuroxime 125 Thymol + Menthol Strength: 2.5 mg, 10 mg
Indications: Non-Small Cell mg + Clavulanic acid 31.25 Strength: 120 ml & 250 ml Dosage Form: Tablet
lung cancer, pancreatic mg )/5 ml (70 ml) Bottle Indications: Acute
cancer. Dosage Form: Powder for Dosage Form: Solution Coronary Syndrome (ACS),
Suspension. Indications: Dental Stroke and Systemic
Brand Name:  Buflex® Indications: ENT plaque, gingivitis & bad Embolism, Deep Vein
Generic Name:  Infections, dental breath. thrombosis (DVT) &
Nabumetone infections, post-surgical Pulmonary Embolism (PE).
Strength: 500 mg & 750 mg infections, gynaecological
Dosage Form:  Tablet infections, RTI, SSTI & UTI.
Indications: Osteoarthritis,
rheumatoid arthritis and Brand Name: Ocaliva
musculoskeletal pain Generic Name: Obeticholic Acid
Strength: 5 mg, 10 mg
Brand Name: Cardocal® Dosage Form: Tablet
Generic Name:  Cilnidipine Indications: Primary biliary cholangitis (pbc), non-
Strength: 5 mg & 10 mg alcoholic steato-hepatitis (nash), portal hypertension
Dosage Form:  Tablet compensated cirrhosis, bile acid diarrhoea, non-
Indications: Hypertension. alcoholic fatty liver disease (NAFLD).

Brand Name: Enoma Brand Name: Ortho-D3 Brand Name: Bestcef
Generic Name: Enoxaparin Generic Name: Generic Name: Cefixime
Sodium Cholecalciferol Strength: 21 ml
Strength: 40 mg, 60 mg Strength: 1000 IU, 2000 IU Dosage Form: Powder for
Dosage Form: Pre-Filled & 1000 IU/5 ml (100 ml) Paediatric Drops
Injection Dosage Form: Tablet & Indications: Typhoid
Indications: Oral Solution fever, upper and
Prophylaxis of venous Indications: lower respiratory tract
thromboembolism, Cholecalciferol (Vitamin infections, urinary tract
stroke, unstable angina, D3) deficiency states & infections, gonococcal
deep vein thrombosis & inadequate absorption urethritis & cervicitis,
pulmonary embolism. of calcium, osteoporosis, acute otitis media.
hypoparathyroidism,
rickets & osteomalacia.

THE PHARMA WORLD 7



Eskayef

Brand Name: Empavic Brand Name: Aceten Brand Name: Aceten Brand Name: Lasmi
Generic Name: Generic Name: Generic Name: Generic Name: Lasmiditan
Empagliflozin Acetylcysteine BP Acetylcysteine BP Strength: 50mg, 100mg
Strength: 10 mg, 25 mg Strength: 600 mg Strength: 100 mg Sachet Dosage Form: Tablet
Dosage Form: Tablet Dosage Form: Effervescent Dosage Form: Powder for Indications: Acute
Indication: Type-2 Diabetes. tablet oral Solution treatment of migraine with
Indications: To clear mucus Indications: To clear mucus or without aura in adults.
Brand Name: Moxif 400 in respiratory conditions in respiratory conditions
Generic Name: like-bronchitis, COPD, like-bronchitis, COPD,
Moxifloxacin pneumonia, cystic fibrosis. pneumonia, cystic fibrosis.
Strength: 400 mg
Dosage Form: Tablet Brand Name: Tems Brand Name: Cistor™ Brand Name: Ostocal C
Indications: RTIs, Generic Name: Telmisartan Generic Name: Cisplatin Generic Name: Coral
pneumonia, SSTIs, acute Strength: 20mg, 40 mg, 80 Strength: 50 mg Calcium + Vitamin C
chronic bronchitis & mg Dosage form: Liquid Strength: 260mg + 500mg
typhoid Fever. Dosage Form: Tablet Injection Dosage Form: Effervescent
Indications: For Treatment Indications: Advanced Tablet
Brand Name: Vcand of hypertension & testicular cancer, advanced Indications: Surgical wound
Generic Name: cardiovascular risk ovarian cancer & advanced healing, maintenance of
Voriconazole reductions in patients bladder cancer. healthy bone & teeth for
Strength: 200 mg, 50 mg unable to take ACE children, maintenance of
Dosage Form: Tablet Inhibitors. immune system.
Indications:
Dermatophytosis, Euro Pharma
Invasive Aspergillosis,
Deep Tissue Infections &
Esophageal Candidiasis.

Brand Name: Tolema Brand Name: Savonil Brand Name: Hexihygin Brand Name: EURO Gel
Generic Name: Generic Name: Generic Name: Generic Name: Ethanol +
Tolfenamic Acid Chlorhexidine Gluconate + Chlorhexidine Gluconate + Isopropyl Alcohol
Strength: 200 mg Cetrimide Isopropyl Alcohol Strength: 66 % + 3.5 %
Dosage Form: Tablet Strength: 0.3% + 3% Strength: 0.5% + 70 % Dosage Form: Gel
Indications: Migraine & Dosage Form: Solution Dosage Form: Hand Rub Indication: Prevention from
headache. Indication: Disinfection, Indication: Pre-operative being infected by germs,
cleansing and irrigating hand disinfection, kills viruses, bacteria and
the skin or dirty wounds. disinfection of clean and other germs.
intact skin.

THE PHARMA WORLD 9



Everest Goodman Brand Name: Tajenta Brand Name: Litam
Generic Name: Linagliptin Generic Name:
Brand Name: Fineron Hamdard INN Levetiracetam USP
Generic Name: Strength: 5 mg Strength: 250 mg & 500 mg
Finerenone INN Brand Name: Kulzam Dosage Form: Tablet Dosage Form: Tablet
Strength: 10 mg Generic Name: Aab-e- Indications: Type 2 Indications: Partial
Dosage Form: Film coated Hayat diabetes mellitus. seizures, myoclonic &
tablet Composition: Each 5 ml tonic-clonic seizures.
Indications: To reduce the contains- Camphor 1.61 Brand Name: Tajenta-M
risk of sustained eGFR g, Thymol 0.81 g, Menthol Generic Name: Linagliptin
decline, end-stage kidney 0.40 g, Eucalyptus oil INN + Metformin HCl BP
disease, cardiovascular 0.52 ml, Pine oil 0.26 ml, Strength: 2.5 mg + 500 mg
death, nonfatal Caraway oil 0.26 ml, Anisi & 2.5 mg + 850 mg
myocardial infraction, oil 0.19 ml and Tincture of Dosage Form: Tablet
and hospitalization for ginger 0.19 ml. Indications: Type 2
heart failure in adult Dosage From: Drop diabetes mellitus.
patients with chronic Indications: Respiratory
kidney disease (CKD) tract & lung infection, Brand Name: Ispa Plus (Sugar Free)
associated with type 2 pneumonia, catarrh, Generic Name: Isabgul Spicy
diabetes (T2D) Cough & Cold, Headache, Composition: Each Sachet contains- Plantago ovata (husk)
Cuts, Insect’s bite and 3 g, Cassia angustifolia 1 g and other excipient Q.S.
Brand Name: Olixar 20 different type of pains & Dosage From: 20 Sachets
Generic Name: Rheumatism. Indications: Constipation, piles, IBS, hyperlipidemia and
Olanzapine BP bowel regulation for bed ridden patient.
Strength: 20 mg
Dosage Form: Film coated Brand Name: Neement Brand Name: Hamdard
tablet Generic Name: Marham Neem Balm
Indication: Schizophrenia, Composition: Each gram Generic Name: Marham
prevention of bipolar ointment contains – Azadi- Ajeeb
disorder, mania rachta indica 88.88mg, Del- Composition: Each gram
phinium denudatum 5.55mg, ointment contains-
Brand Name: Renocal Plus Pinus longifolia 22.22mg, Cinnamomum camphora
Generic Name: Calcium Curcuma longa 44.44mg, 200 mg, Menthol 200 mg &
Acetate + Heavy Cedrus deodara 44.44mg, Thymol 100 mg.
Magnesium Carbonate Glycyrrhiza glabra 44.44mg, Dosage From: 20g
Strength: 435mg + 235mg Lawsonia inermis 44.44mg, Ointment
Dosage Form: Tablet Lamp-black 44.44mg, Acacia Indications: Headache,
Indication: Treatment of arabica 88.88mg, Onosma pain, backache, sprain,
hyperphosphatemia asso- echioides 88.88mg and Ses- sciatica, insect bites &
ciated with chronic renal amum indicum oil 0.89ml. cuts.
insufficiency in patients Dosage From: Ointment
undergoing dialysis. Indications: Skin infection,
minor cuts, infected ulcers
as wounds, inflammation &
skin diseases.

THE PHARMA WORLD 11

Brand Name: Hamdard Bhringaraj Brand Name: Amlasia
Generic Name: Mahabhringaraj Taila Generic Name: Amalaki
Composition: Each 5 ml oil contains- Sesamum Rasayan
indicum 5.63 g, Eclipta alba 22.54 ml, Rubia cordifolia Composition: Each 5
0.17 g, Prunus cerasoides 0.17 g, Symplocos racemosa ml contains as extract-
0.17 g, Pterocarpus santalinus 0.17 g, Red Ochre Phyllanthus emblica Juice)
0.17 g, Sida cordifolia 0.17 g, Curcuma longa 0.17 g, 3.03 ml, Piper longum 0.12
Berberis aristata 0.17 g, Mesua ferrea 0.17 g, Callicarpa g & Honey 0.36 g.
macrophylla 0.17 g, Hibiscus mutabilis 0.17 g and Dosage From: Syrup
Ichnocarpus frutescens 0.17 g. Indications: Hyperacidity,
Dosage From: 130 ml Hair Oil dyspepsia, flatulence,
Indications: Hair fall, premature graying of hair, heartburn, anorexia,
dandruff, headache and insomnia. anaemia, heart disease &
jaundice.
Brand Name: Hamdard Basak
Generic Name: Vasakarista
Composition: Each 5 ml contains as extract- Adhatoda
vasica 0.68 g, Piper longum 0.14 g, Vitis vinifera 0.14 g,
Honey 3.47 g, Woodfordia fruticosa 1.14 g, Terminalia
chebula 73.24 mg, Glycyrrhiza glabra 6.78 mg, Saussurea
hypoleuca 6.78 mg, Acorus calamus 6.78 mg, Zingiber
officinale 6.78 mg, Piper nigrum 6.78 mg, Syzygium
aromaticum 6.78 mg, Elettaria cardamomum 6.78 mg,
Cinnamomum tamala 6.78 mg, Cinnamomum zeylanicum
6.78 mg, Rhus succedanea 6.78 mg & Myrica nagi 6.78 mg.
Dosage From: Syrup
Indications: Dry irritable cough, allergic & smoker’s cough,
hoarseness of voice & sore throat, asthma and respiratory
tract infection.

IBN Sina Brand Name: Lister Plus 250 ml Mouthwash
Generic Name: Eucalyptol USP, Menthol USP, Methyl
Brand Name: Dermacom Salicylate BP, Thymol BP, Sodium Fluoride BP.
Cream Strength: (0.092 gm+ 0.042 gm+ 0.060 gm+ 0.064 gm+
Generic Name:Ofloxacin USP 0.020 gm)/ 100 ml (250 ml)
0.75%, Ornidazole INN 2%, Dosage Form: Mouthwash
Terbinafine Hydrochloride Indication: It helps to prevent cavities, restores teeth
BP 1%, Clobetasol enamel, kills germs that cause bad breath, reduces
Propionate USP 0.50% plaque, gingivitis, reduces gum disease and keeps
Strength: 15 gm teeth clean, bright & healthy.
Dosage Form: Cream
Indication: This cream is Brand Name: Bester 250 ml
indicated in the treatment Mouthwash
of- mixed and complicated Generic Name: Benzydamine
fungal, protozoal & Hydrochloride BP 0.15%
bacterial infections, Strength: 1.5 mg/ml
mild to moderate Dosage Form: Mouthwash
vaginitis, candidiasis and Indication: It is indicated for
trichomoniasis, pruritus the symptomatic relief of
vulvae, dermatitis, eczema, inflammatory condition of
genito-urinary infections. mouth and throat.

12 THE PHARMA WORLD

Navana

Brand Name: Pravalip Indications: Pravalip is an HMG-CoA reductase inhibitor (statin) indicated as an
Generic Name: Pravastatin adjunctive therapy to diet to: l Reduce the risk of Myocardial Infarction (MI),
Sodium BP revascularization, and cardiovascular mortality in hypercholesterolemic patients without
Strength: 10 mg & 20 mg. clinically evident Coronary Heart Disease (CHD). l Reduce the risk of total mortality
Dosage Form: Tablet by reducing coronary death, Myocardial Infarction (MI), revascularization, stroke/
Transient Ischemic Attack (TIA), and the progression of coronary atherosclerosis in
patients with clinically evident Coronary Heart Disease (CHD). l Reduce elevated Total
Cholesterol (TC), Low Density Lipoprotein Cholesterol (LDL-C), Apolipoprotein B (ApoB)
and Triglycerides (TG) levels and to increase High Density Lipoprotein Cholesterol (HDL-C)
in patients with primary hypercholesterolemia and mixed dyslipidemia. l Reduce
elevated serum Triglycerides (TG) levels in patients with hypertriglyceridemia. l Treat
patients with primary dysbetalipoproteinemia who are not responding to diet. l Treat
children and adolescent patients ages 8 years and older with heterozygous familial
hypercholesterolemia after failing an adequate trial of diet therapy.

Brand Name: Nabuton Brand Name: Ertuglif
Generic Name: Generic Name: Ertugliflozin
Nabumetone BP INN
Strength: 500 mg & 750 mg. Strength: Ertugliflozin L-Pyro-
Dosage Form: Film coated glutamic Acid INN equivalent
tablet to Ertugliflozin 5mg & 15mg.
Indications: Nabuton Dosage Form: Film coated
tablet is indicated tablet
for acute and chronic Indications: Ertugliflozin is
treatment of sign and indicated as an adjunct to
symptoms of osteoarthritis diet and exercise to improve
and rheumatoid arthritis. glycaemic control in adults
with type 2 diabetes mellitus.

Nipro JMI

Brand Name: Medulax Brand Name: Medulax Brand Name: Laxitab Brand Name: Bonestar Kit
Tablet Syrup Generic Name: Generic Name: Ibandronic
Generic Name: Butamirate Generic Name: Butamirate Prucalopride Acid + Calcium Orotate
Citrate Citrate Strength: 1 mg & 2 mg Strength: 150 mg + 400 mg
Strength: 50 mg Strength: 7.5 mg/5 ml Dosage Form: Tablet Dosage Form: Tablet
Dosage Form: Sustained Dosage Form: Syrup Indication: Chronic Indication: Treatment &
Release Tablet Indication: Dry cough. Idiopathic Constipation. prevention of postmeno-
Indication: Dry cough. pausal osteoporosis.

THE PHARMA WORLD 13



One Pharma

Brand Name: Merostat Brand Name: Unzip Brand Name: Onvicon Plus Brand Name: Onvicon DX
Generic Name: Meropenem Generic Name: Flupentixol Generic Name: Sodium Generic Name: Sodium
Strength: 1 gm + Melitracen Alginate + Sodium Alginate + Sodium
Dosage Form: IV Injection Strength: 0.5 mg + 10 mg Bicarbonate + Calcium Bicarbonate + Calcium
Indication: Pneumonia, Dosage Form: Tablet Carbonate Carbonate
UTI, pelvic inflammatory Indication: Anxiety and Strength: 500mg + 267 mg + Strength: 500mg + 213mg +
disease, SSTIs, meningitis, depression. 160 mg (200 ml) 325 mg (200 ml)
intra-abdominal infections. Dosage Form: Suspension Dosage Form: Suspension
Indication: Heartburn & Indication: Fast relief
indigestion from GERD, heartburn,
indigestion & dyspepsia.

Brand Name: Trescof Brand Name: Moxibest Brand Name: Triponel
Generic Name: Guaifenesin Generic Name: Moxifloxacin Generic Name:
+ Dextromethorphan Hbr + Strength: 400 mg Dextromethorphan Hbr
Menthol Dosage Form: Tablet + Phenylephrine HCl +
Strength: 200 mg + 15 mg + Indication: CAP, sinusitis, Triprolidine HCl
15 mg (100 ml) tonsillitis, AECB, acute Strength: 20 mg + 10 mg +
Dosage Form: Syrup otitis media. 2.5 mg (100 ml)
Indication: Wet cough, sore Dosage Form: Syrup
throat & chest congestion. Indication: Dry cough,
nasal congestion & allergic
rhinitis.

Organic

Brand Name: Asmiket Brand Name: Clonafix
Generic Name: Ketotifen Generic Name: Clonazepam
Strength: 1 mg Strength: 0.5 mg & 2.0 mg
Dosage Form: Tablet Dosage Form: Tablet
Indication: Allergy Indications: Panic attack, epilepsy, status
conjunctivitis, asthma epilepticus, Lennox-Gastaut syndrome, infantile
prophylaxis. spasm, absence seizure, myoclonic seizure,
tonic-clonic seizure, akinetic and atonic seizure,
partial seizure, bipolar affective disorder, drug-
induced dyskinesia, choreiform movement,
fulgurant pain, Tourette’s syndrome, resistant
depression, nocturnal myoclonus, trigeminal
neuralgia.

THE PHARMA WORLD 15

Pharmasia

Brand Name: Precid PFS Brand Name: Airup 5 Brand Name: Clonzy 1 Brand Name: Pyrica 25
Generic Name: Famotidine Generic Name: Montelukast Generic Name: Clonazepam Generic Name: Pregabalin
Strength: 40 mg/5 ml (50 Strength: 5 mg Strength: 1 mg Strength: 25 mg
ml) Dosage Form: Chewable Dosage Form: Tablet Dosage Form: Capsule
Dosage Form: Powder for Tablet Indications: Social Anxiety Indications: Diabetic
Suspension Indications: Asthma, Disorder, Phobia, Sleep Peripheral Neuropathy,
Indications: GERD, Gastric Allergic Rhinitis, Disorder, Panic Disorder. Post-herpetic Neuralgia,
Ulcer, Duodenal Ulcer & Exercise-Induced Fibromyalgia,
Hyperacidity. Bronchoconstriction. Spinal Cord Injury.

Popular

Brand Name: Nabumax
Generic Name: Nabumetone
Strength: 500 mg & 750 mg
Dosage Form: Tablet
Indications: Rheumatoid arthritis &
osteoarthritis related pain management

Brand Name: Gavicool Brand Name: Hi-Flow D Brand Name: Hi-Flow
Double Action Generic Name: Tamsulosin Generic Name: Tamsulosin
Generic Name: Sodium Hydrochloride & Dutasteride Hydrochloride
Alginate, Sodium Strength: 0.4mg Sustained Release Strength: 0.4 mg Modified Release
Bicarbonate, Calcium & 0.5mg Immediate Release Capsule Capsule
Carbonate Dosage Form: Capsule Dosage Form: Capsule
Strength: (500 mg + 213 mg Indications: Treatment of signs Indications: Treatment of signs
+ 325 mg)/10 ml and symptoms of benign prostatic and symptoms of benign prostatic
Dosage Form: Suspension hyperplasia (BPH). hyperplasia (BPH)
Indications: Heartburn,
Indigestion, Flatulence. Brand Name: Vasculex
Generic Name: Phenylephrine Hydrochloride
Strength: 0.5 mg/5 ml Injection
Dosage Form: IV Injection
Indications: Treatment of clinically important
hypotension resulting primarily from
vasodilation in the setting of anesthesia.

16 THE PHARMA WORLD

Renata

Brand Name: Bendopa Brand Name: Cipran Brand Name: Nexdex Brand Name: Seronex
Generic Name: Levodopa Generic Name: Generic Name: Generic Name: Sertraline
USP + Benserazide Levomilnacipran Dexlansoprazole Hydrochloride BP.
Hydrochloride Ph. Eur. Hydrochloride INN. Strength: 30 mg & 60 mg Strength: 25 mg, 50 mg &
Strength: 50 mg + 100 mg Strength: 40 mg, 80 mg Dosage Form: Capsule 100 mg
Dosage Form: Dispersible Dosage Form: Extended Indication: Non Erosive Dosage Form: Tablet
Tablet Release Capsule Reflux Disease (NERD), Indication: Major
Indication: For the Indication: Major erosive esophagitis, Depressive Disorder (MDD),
treatment of all forms of Depressive Disorder relapsed esophagitis, Obsessive Compulsive
Parkinson’s syndromes (MDD) in adults. Acute refractory GERD, nocturnal Disorder (OCD), Panic
with the exception depression, atypical reflux & sleep disturbance, Disorder (PD), Postpartum
of medicine-induced depression, refractory functional dyspepsia, Depression (PPD), Social
parkinsonism. It is also depression, relapsed morning sickness, gastric/ Anxiety Disorder (SAD),
indicated in Parkinson-like depression, seasonal duodenal ulcer, Barrett’s Post Traumatic Disorder
symptoms such as tremor, depression & functional esophagus etc. (PTSD), Pre-Menstrual
shakiness, stiffness and impairment. Dysphoric Disorder (PMDD),
difficulty moving. Pre-Mature Ejaculation
(PME) and serotonin
deficiency related multiple
indications.

Sharif

Brand Name: Travelit
Generic Name: Cyclizine Hydrochloride BP.
Strength: 50 mg
Dosage Form: Oral Tablet
Indications: Prevention and treatment of travelers’ nausea and
vomiting motion sickness. Also used in PONV (Postoperative
Nausea & Vomiting), Meniere’s disease etc.

Square

Brand Name: Teconin Brand Name: Rapilog
Generic Name: Teicoplanin BP Generic Name: Insulin Aspart
Dosage Form: IM/IV Inj. Dosage Form: Injection, Pen Cartridge
Strength: 200 mg & 400 mg Strength: 100 IU/ml
Indication: Bone infection Indication: Type-1, Type-2 & gestational diabetes
(Osteomyelitis), joint infection (Septic
arthritis), heart infection (Endocarditis),
Ventilator Associated MRSA Pneumonia
(VAMP) due to MRSA and other Gram-
positive microorganisms. Any other
infections caused by or suspected
due to MRSA and other Gram-positive
microorganisms

THE PHARMA WORLD 17



Brand Name: Caripa Brand Name: Nasovap Brand Name: Ceevit
Generic Name: Carica Generic Name: Menthol + Generic Name: Vitamin-C
Papaya Leaf Extract Eucalyptus Oil Dosage Form: Syrup
Dosage Form: Syrup Dosage Form: Suspension Strength: 100 mg/5 ml
Strength: 275 mg/5 ml for Inhalation Indication: Vitamin C is
Indication: Thrombocyto- Strength: 2% w/v + 10% v/v used for prevention and
penia, thrombocytopenia Indication: For relief of the treatment of vitamin C
associated with dengue symptoms of coughs, colds deficiency in pediatric &
& chemotherapy and blocked noses adults. It can be indicated
in pregnancy, lactation,
Team Pharma Scurvy, infection, trauma,
burns, cold exposure,
following surgery, fever,
stress, peptic ulcer, cancer.
Vitamin C is used as an
immune booster in infants
receiving unfortified
formulas.

Brand Name: Zolvo ® PFS Brand Name: Zolvo ® Brand Name: Zolvo ® Brand Name: Gaviplus ®
Generic Name: Generic Name: Voriconazole Generic Name: Generic Name: Sodium
Voriconazole Strength: 200 mg Voriconazole 50 mg Alginate + Sodium
Strength: 40 mg/ml Dosage Form: Tablet Strength: 50 mg Bicarbonate + Calcium
Dosage Form: Powder for Indication: Invasive aspergil- Dosage Form: Tablet Carbonate
suspension losis, Fluconazole resistant Indication: Invasive Strength: (500 mg + 267 mg
Indication: Invasive serious candida infection, aspergillosis, Fluconazole + 160 mg)/10 ml
aspergillosis, Fluconazole esophageal candidiasis. resistant serious candida Dosage Form: Oral
resistant serious candida infection esophageal Suspension
infection, esophageal Brand Name: Emlozin ® candidiasis. Indication: Heartburn,
candidiasis. Generic Name: indigestion, gastro
Empagliflozin Brand Name: Emlozin ® Esophageal Reflux Disease,
Strength: 10 mg Generic Name: hyperacidity.
Dosage Form: Tablet Empagliflozin
Indication: Type II Diabetes Strength: 25 mg
Mellitus Dosage Form: Tablet
Indication: Type II Diabetes
Mellitus

THE PHARMA WORLD 19



Brand Name: Uritro ® Brand Name: Nerupa ® Brand Name: Recicof ® Kidz Brand Name: Recicof ®
Generic Name: Generic Name: Rupatadine Generic Name: Citric Acid Generic Name: Citric Acid
Nitrofurantoin Strength: 5 mg/5 ml Monohydrate Monohydrate
Strength: 25 mg/5 ml Dosage Form: Syrup Strength: 31.25 mg/5 ml Strength: 125 mg/5 ml
Dosage Form: Suspension Indication: Symptomatic Dosage Form: Linctus Dosage Form: Linctus
Indication: Urinary tract treatment of seasonal and Indication: Dry cough and Indication: Dry cough and
infections. perennial allergic rhinitis sore throat. sore throat.
and urticarial.

Brand Name: Desotem ® Brand Name: Sertazol ® patients 12 years of age
Generic Name: Desloratadine Generic Name: and older caused by
Strength: 2.5mg/5 ml Sertaconazole Nitrate 2% trichophyton rubrum.
Dosage Form: Syrup Strength: 20 mg
Indication: Relief of symptoms Dosage Form: Cream
associated with seasonal and Indication: Treatment
perennial allergic rhinitis, such of interdigital tinea
as sneezing, nasal discharge pedis and other topical
and itching. fungal infections in
immunocompetent

DBL Pharma

Brand Name: Rovius Brand Name: Doxecure Brand Name: Accuzith PFS Indications: l Upper re-
Generic Name: Rosuvastatin Generic Name: Doxofylline Generic Name: Azithromycin spiratory tract infections
Strength: 5 mg & 10 mg Strength: 200 mg Strength: 200 mg/5ml including sinusitis, phar-
Dosage Form: Tablet Dosage Form: Tablet Dosage Form: Powder for yngitis and tonsillitis l
Indications: Heterozygous Indications: Chronic Ob- Suspension Lower respiratory tract in-
Hypercholesterolemia (Fa- structive Pulmonary Disease fections including commu-
milial and Nonfamilial), (COPD), Bronchial asthma nity acquired pneumonia,
Homozygous Hypercholes- and, Pulmonary Disease As- bronchitis, acute bacterial
terolemia (Familial), Mixed sociated with Bronchospasm exacerbations of Chronic
Dyslipidemia Obstructive Pulmonary
Disease (COPD) l Otitis
Brand Name: Diablo media and Otitis externa
Generic Name: Metformin l Skin and skin structure
Strength: 500 mg & 850 mg infections including cellu-
Dosage Form: Tablet litis, pyoderma, erysipelas,
Indications: Indicated as an wound infections l Mild
adjunct to diet and exercise or moderate typhoid fever
to improve glycemic control due to multiple antibacte-
in children and adults with rial resistant organisms.
type-2 diabetes mellitus.

THE PHARMA WORLD 21

filtrpautiroiTnfih,cesaeutpiloatinrmacathitaoenlsleoanlnugdteisons for ... leader in Fluid Management

DGDA NEWS

DGDA team participates in
Innovator Biologics & Biosimilar
Regulatory Seminar in USA

Major General Mohammad Yousuf, Director General
and Mr. Md. Salahuddin, Director, Directorate General
of Drug Administration (DGDA) took part in Innova-
tor Biologics & Biosimilar Regulatory seminar held in
Boston on 28-29 June which was organized by Ameri-
can Conference Institution. On July 1, 2022 they visited
Genentech Biotech Plant at Vacaville, Sanfrancisco,
USA.

They also visited USP Headquarters of USP in USA
at Rockville, Maryland, USA on 5-6 July, 2022. The team
visited USP Chemical & Biological standardization lab-
oratories and met senior management.

The Director General had a very successful meeting
with the senior management personnel of USP-PQM+.

THE PHARMA WORLD 23

Eskayef felicitates new FCPS
Graduates in Oncology

Eskayef Pharmaceuticals LTD., one of advancements happening around the for an ameliorated service of cancer
the leading pharmaceuticals compa- globe in oncology,” he added. patients of Bangladesh”.
ny of Bangladesh, recently arranged
the felicitation ceremony of new Brig. Gen. Prof. Dr. Md. Yousuf Dr. Md. Mujahidul Islam, Executive
FCPS graduates in the field of oncol- Ali attended the event as the chief Director Marketing & Sales of Eskayef
ogy. The ceremony welcomed nine guest and encouraged the young on- Pharmaceuticals Ltd. expressed ex-
new oncologists to the community in cologists. “The new graduates should pressing his heartiest gratitude to the
presence of the leading oncologists work diligently & efficiently for the new fellows. Eskayef Oncology as the
of Bangladesh. betterment of cancer patients lives 1st & Only EU GMP & ANVISA-Brazil ac-
as independent oncologists. A proper credited oncology facility is working
FCPS in the field of oncology has treatment planning & timely deci- to ensure manufacturing of premium
been a very prestigious degree for sion-making should always be the key quality anticancer products relaying a
which a good number of aspirants of focus, he added”. bridge of trust among doctors & pa-
participate each year. Among the par- tients both in Bangladesh & around
ticipants, only eight brilliant doctors The special guest of this event was the globe”, he added.
could achieve this elite degree this Prof. Dr. Rakib Uddin Ahmed, a reputed
year. Eskayef oncology arranged the professor of the department of radia- Eskayef Oncology started its jour-
program to celebrate this great ac- tion oncology of National Institute of ney in 2018 and within a short span
complishment of these luminous on- Cancer Research & Hospital who also of 4 years it established itself as one
cologists. congratulated the fellows. “Amidst the of the leaders in the field of oncology.
dire necessity of independent oncolo- It has already launched numerous
This program was chaired by the gists in Bangladesh, new fellow oncol- advanced chemotherapeutics and is
renowned oncologist, the director ogists will surely put a pivotal contri- working relentlessly to bring mono-
of National Institute of Cancer Re- bution to fill the gap in the service of clonal antibodies to save the lives of
search & Hospital, Prof. Dr. Swapan cancer patients,” he said. millions of cancer patients, says the
Bandyopadhyaa. Prof. Bandyopad- company press release.
hyaa welcomed the new oncologists Among the fellows, Dr. Samina Is-
& congratulated them, “An oncologist lam, Clinical fellow, National Univer- Dr. Kazi Iftekhar Uddin Ahmed,
is like the savior figure for their can- sity Hospital, Singapore said, “The Senior Oncologist of NICRH, Mr. Binay
cer patients. The New Fellows will be journey & experience at NUH will add Das, Associate Director- Marketing of
working to ensure providing a quality great value to work at clinical settings Eskayef and Dr. Mahbubur Rahamn,
service to ease the distress of their in Bangladesh. Another fellow Dr. Na- Head of Sales were also present. The
patients. For this, doctors should al- hid Naznin Rinky, FCPS said, “Constant program was hosted by Dr. Md. Shah-
ways remain updated with the recent dedication & sacrifice led to this mo- riar Islam, Group Product Manager,
ment & would like to work coherently SK+F Oncology.

24 THE PHARMA WORLD

NEWS

An Effort towards a Cervical Cancer free nation

Cervical cancer is the second most common topic of ‘An effort towards a cervical cancer
cancer death among females in Bangladesh and free nation’ held in Pan pacific Sonargaon. To
fourth in worldwide. According to the report, eliminate cancer, the need for regular screen-
almost ten thousand women in Bangladesh die ing and HPV vaccine has been briefly discussed.
of cervical cancer and 50 million of females of With the initiation of the Papilovax, how it may
this country are at risk for cervical cancer. The contribute to the govt target to achieve cervical
reason behind the high death rate is due to the cancer free nation and how it fills up the long
lack of awareness and years of neglect. However gap created due to the unavailability of the of
good news is that Cervical cancer is completely HPV vaccine in country for the couple of years
a preventable disease. has been well discussed. The challenges and
the opportunities of this vaccine has also been
To eliminate the cervical cancer, HPV vaccine briefly disserted. Prof Dr TA Chowdhury, Nation-
is the primary step. For the last couple of years al professor Prof Shahla Khatun were the chief
there was a huge gap on availability of this vac- guest and Prof Dr Ferdousi Begum, President of
cine in Bangladesh. Incepta has come forward OGSB chaired the program. The seminar started
to fulfil this gap by introducing Papilovax, HPV with the welcome address of Prof Dr Gulshan
Vaccine for the first time in Bangladesh as local Ara, Secretary General of OGSB. On behalf of
manufacturing company. It is a great pride for Incepta, Dr E. H. Arefin Ahmed, Executive Direc-
the country which will pave the way to eliminate tor of Incepta Pharmaceuticals Ltd give vote of
Cervical cancer from the nation. thanks. At the end, Incepta officially unveiled
Papilovax in a grand way and announced the
By administering this vaccine to all healthy commencement of a new era for cervical cancer
women from ages 9-45 years, Bangladesh will go prevention.
a long way to eradicate cervical cancer.

A scientific seminar regarding this on the

Beacon organises free
hepatitis B screening

Beacon Pharmaceuticals Ltd. organises
free hepatitis B screening and vaccina-
tion for all its employees on the oc-
casion of World Hepatitis Day 2022 to
increase the awareness of Hepatitis
in the presence of renowned Hepa-
tologist BSMMU Professor Dr. Mamun
al Mahtab. Mohammad Ebadul Karim,
Managing Director of Beacon Pharma-
ceuticals was also present at the event.

THE PHARMA WORLD 25

Orion offers ‘Orion Medical Scholarship’

As a continuation of Corporate Social in exchange of bringing smile in the meritorious students of each year (1st
Responsibility (CSR), Orion Pharma face of ailing humanity. Orion Pharma year to 5th year) from different Govt.
Ltd. recently conducted an inaugu- Ltd. has decided to be with those Medical Colleges are eligible to apply
ration ceremony of “Orion Pharma masterminds in this voyage towards for this scholarship.
Medical Scholarship” at Orion House a noble mission by offering scholar-
presided by the Company Director and ship to those medical students of the The program ended up with prov-
Trustee of Orion Pharma Welfare Trust country who cannot afford the exorbi- ing Scholarship cheque to 06 (Six)
Mrs. Arzuda Karim & Managing Direc- tant cost of medical education. Orion Medical Students from different
tor of Orion Pharma Ltd. Zareen Karim. Pharma Ltd. is offering scholarships Medical Colleges. Medical students
to 21 (twenty-one) students from dif- along with their parents were present
Orion Pharma always appreciates ferent Govt. Medical Colleges with 5 on this auspicious occasion and ex-
the ‘going-to-be-doctors’ who already (five) students from each academic pressed heartfelt gratitude to Orion
got admitted into the medical college year (1st year to 5th year). All poor and Pharma Management for this noble
and decided to sacrifice their lives mission.

Popular welcomes
new Senior General
Manager, Marketing

Popular Pharmaceuticals has recently
appointed Mohammod Shafiqul Islam
as their new Senior General Manager,
Marketing. Mohammod Shafiqul Islam
brings over 24 years of Pharmaceuti-
cal Marketing, Sales & Distribution.
Dr. Mostafizur Rahman, Managing Di-
rector & CEO; Md. Quamrul Hassan,
Sr. Director, Marketing & Sales; Safiul
Azam FCMA, Director, Finance and Ac-
counts; Md. Ali Hossain, Director, HR
& Admin; Md. Adnan Abdullah, Sen-
ior Manager,PMD; and Md. Muksidul
Haque, Senior Manager, PMD were pre-
sent during the welcoming ceremony.

26 THE PHARMA WORLD

Professor Mamun Al Mahtab CONGRATS
elected as a Fellow of Bangladesh
Academy of Sciences

Bangabandhu Sheikh Mujib Medical University He is the General Secretary of the National
interventional hepatology department found- Organization of Liver Specialists of Bangla-
er head and former chairman of the hepatolo- desh, Association for the Study of Liver Dis-
gy department, Professor Dr. Mamun Al Mahtab eases of Bangladesh, the founding president
Shwapnil was recently elected as a Fellow of of BSMMU Hepatology Alumni Association and
the Bangladesh Academy of Sciences, recently. the founding chairman of the Forum for the
The president of the academy, Professor AK Study of the Liver.
Azad Chowdhury formally read the oath to Pro-
fessor Dr. Mamun Al Mahtab as a Fellow of the He is also Vice President of Eurasian
Bangladesh Academy of Science. Gastroenterological Association, General
Secretary of South Asian Association for
Prof. Shwapnil did his MBBS from My- the Study of the Liver, Executive Member of
mensingh Medical College in 1995, MSc in Asian Pacific Association for the Study of the
Gastroenterology from University of London Liver and International Coordinator of Indian
in 1998, and M.D. in Hepatology from Bang- National Association for the Study of the Liver.
abandhu Sheikh Mujib Medical University in
2006. He is a Fellow of Indian College of Phy- Professor Dr. Mamun Al Mahtab Shwapnil (far
sicians, Royal College of Physicians of Ireland right) taking oath.
and Royal College of Physicians of London.
Prof. Shwapnil is the Founder General Secretary
He is also a Visiting Professor in the Depart- of Bangladesh Stem Cell and Regenerative
ment of Gastroenterology and Metabolism, Medicine Society. He is one of the 12 selected
Ehime University, Japan and a member of the members from around the world of the Inter-
Board of Studies of the Department of Gastro- Academy Partnership’s Working Party on
enterology, All India Institute of Medical Sci- Regenerative Medicine.
ences, Rishikesh, India. He is also one of the
members of the Strategic and Technical Advi- Prof. Shwapnil is the pioneer of Trans-
sory Group on Viral Hepatitis, HIV-AIDS, STIs Arterial Chemo-Embolization (TAICE), a state-
in the Southeast Asian Region of the World of-the-art method in liver cancer treatment in
Health Organization. Bangladesh. He is also a pioneer in autologous
hematopoietic stem cell transplantation,
More than 300 research articles of Prof. plasma exchange and liver dialysis in liver
Shwapnil have been published in various do- failure.
mestic and foreign scientific journals.

Prof. Shwapnil received the ‘Presidential
Distinction’ of the American Association for
the Study of the Liver in 2013 and was awarded
the ‘Order of Merit’ by the Eurasian Gastroen-
terological Association in 2014.

The Kalinga Gastroenterological Foundation
of India awarded him the honorary ‘Bloomb-
erg Oration’ in 2015. His biography was includ-
ed in the 2017 Who’s Who. He was awarded the
‘Elbert Nelson Marquis Lifetime Achievement
Award’ by Marquis Who in 2018.

Two of Prof. Shwapnil’s most important
achievements are the ‘Premio National’ medal
jointly awarded by the Cuban Academy of Sci-
ences in 2019 for Nasvac invention and the
‘Bass Gold Medal Award 2021’ by the Bangla-
desh Academy of Sciences.

THE PHARMA WORLD 27



Aortic valve replaced without SUBSCRIBE TO
chest incision at BSMMU
... and remain
A surgical team of Department of technologies into health teaching, updated!
Cardiology, led by Prof SM Mustafa health care, and health research at
Zaman, has successfully performed the university. 51, Kalabagan 1st Lane,
Transcatheter aortic valve implan- Dhaka-1205, Bangladesh
tation (TAVI) on an 80-year-old man About aortic valve replacement, Tel: +88-02-58155677,
at BSMMU. Dr SM Mustafa Zaman said, “Surgery Cell: +8801677395919
means the use of knives and scis- E-mail:
The patient is currently admitted sors. But we’ve been able to save [email protected]
in Coronary Care Unit (CCU). Tran- the patient’s life by successfully
scatheter Aortic Valve Implantation replacing the aortic valve of an 80 THE PHARMA WORLD 29
(TAVI) is a procedure that replace an year old man’s heart without open-
aortic valve without chest incision ing the chest.
or anaesthesia. Experts see this as
a new milestone in the continuous Many people in our country do
success of interventional cardiol- not have the ability to avail this
ogy. treatment. We want to establish this
cutting-edge surgical procedure in
Vice Chancellor of BSMMU, Dr Md our country.” He urges support from
Sharfuddin Ahmed has congratulat- the government to serve the de-
ed the surgery team for successfully serving patients of the country.
performing the first ever Transcath-
eter aortic valve implantation (TAVI). Additionally, he expressed his
He stated that the current adminis- intention to organize training
tration is committed to incorporat- sessions on TAVI—its success
ing cutting-edge medical science rate, complications, and future pos-
sibilities.

NEWS Knowledge and skills needed to provide vaccination
services defined in new FIP reference guide

Pharmacists are well positioned in communi- guide: Knowledge and skills to support pro-
ties to provide vaccine-related services, but fessional development and inform pharmacy
variation across the scope and content of education in vaccination” is that it ties FIP’s
available training programmes means they 21 Development Goals to the policy enablers

often require support to do so effectively. A required for workforce and education to
new reference guide published by FIP is in- transform vaccination. It also provides useful
tended to guide practising pharmacists and tables, built from existing FIP resources that
pharmacy undergraduates in acquiring the outline the skills, techniques, quality assur-
necessary knowledge and skills, and to help ance measures and procedures that pharma-
education providers to develop and/or pro- cy students and practising pharmacists will
vide these knowledge and skills. need to acquire as they develop their com-

A feature of “The FIP vaccination reference petence to provide vaccine-related services.

Pharmacists’ impact on Barriers and enablers to
global vaccination rates vaccination across the
is growing, according regions determined
to new FIP report
Regional challenges and enablers to lev-
Pharmacists are contributing to expanded eraging pharmacists as vaccinators are re-
immunisation coverage globally, thereby vealed in a report by FIP. These factors were
reducing illness and deaths from vaccine- determined during a series of round tables
preventable diseases. This is a finding from held by FIP earlier this year. “By exploring
a new report, published by FIP.  “Advocating the barriers, we can unveil possible path-
expansion of the pharmacist’s role in im- ways for interprofessional collaboration and
munisation: A focus on diphtheria-tetanus- task sharing when it comes to vaccination
pertussis booster, COVID-19 and meningitis services. By doing so, we may achieve higher
vaccinations” provides intelligence from 36 vaccination uptake and provide better ac-
countries around the world on pharmacists’ cessibility and convenience to the people
current role in vaccination services. The new that most need being vaccinated, leaving
data show that their role has expanded since no-one behind,” said Ronald Guse, chair of
the publication of a previous FIP report in the FIP Forum of Professional Regulators.
2020. 78% of countries surveyed allow vac- The report serves as a starting point for
cines administration at community pharma- more vaccine-related discussions around
cies, and a third of countries allow pharma- the world in order to enable multi-profes-
cists to prescribe some vaccines. sional vaccine prescribing and administra-
tion as a patient-centred approach.

New diabetes FIP has published a “Knowledge and skills The guide acknowledges that there are
reference reference guide for professional develop- some barriers to and regulations around
guide focuses ment in diabetes”. providing diabetes-related services in
on helping some countries but emphasises that
pharmacists FIP has been championing the role of “the incorporation of pharmacists into
achieve pharmacists in preventing and treating multidisciplinary diabetes care teams
required chronic diseases, including diabetes, since should always be strongly considered by
competencies 2006, and this latest guide will help phar- clinicians and health policymakers”. The
macists to identify and acquire the com- authors write: “By expanding the full po-
petencies, such as screening and clinical tential of pharmacists in the delivery of
management for patients with diabetes. diabetes care and associated services, we
get closer to offering optimal health ser-
The new FIP publication is intended to vices to patients making sure that no one
guide the design and delivery of educa- is left behind.”
tion and training programmes by continu-
ing professional development providers.

30 THE PHARMA WORLD

SEMINAR

Bangladesh drug-makers for continuation
of TRIPS waiver until 2033

Bangladesh drug-makers and business lead- dul Muktadir called for negotiating with WTO for
ers said they need continuation of the in- extending the TRIPS transition period relating to
tellectual property rights waiver for the pharmaceutical products for Bangladesh until
pharmaceutical industry until 2033 – some six 01 January 2033 even if the country graduates
years after the country’s graduation from the from the LDC status.
least developed country status in late 2026.
The privilege is supposed to come to an end BUILD Chairperson Nihad Kabir emphasized
with the LDC graduation. on enhancing the country’s legal expertise for
They came up with the observations at a effective formulation and implementation of the
seminar titled ‘Preparedness of Pharmaceuti- intellectual property rights-related provisions.
cal Sector for LDC Graduation’ jointly organized
by Support to Sustainable Graduation Project DCCI President Rizwan Rahman said the gov-
(SSGP) of Economic Relations Division (ERD) ernment should establish ‘Biotech Park’ and
and Business Initiative Leading Development ‘Genome Valley’ to facilitate biotechnological
(BUILD) in Dhaka. research. He also called for giving incentives to
Salman F Rahman, Private Industry and In- pharmaceutical sector like RMG sector.
vestment Adviser to the Prime Minister, called
for engaging lobbyist firm in the WTO for the Secretary of the Ministry of Industries Zakia
continuation of TRIPS waiver for Bangladesh af- Sultana assured that the government would
ter graduation. work in close collaboration with the private sec-
He also emphasized the quick operationali- tor in amending the current patent law of the
zation of API (Active Pharmaceutical Ingredients) country.
parks and called for immediate closure of the
mailbox system created back in 2008 for submit- Speakers also said the “Bangladesh Patent
ting patent applications as the mailbox system Law 2022” should be amended in line with the
has lost its relevance in the present context. changing perspectives of the local pharma-
President of Bangladesh Association of Phar- ceutical industry ahead of the country’s LDC
maceutical Industries (BAPI) Nazmul Hassan graduation.
said the issues of affordability and public health
should be taken into consideration while grant- ERD Secretary Sharifa Khan urged for a
ing patent under the patent law of the country. stronger partnership between the public and
Managing Director of Incepta Pharmaceuti- private sector for preparing the pharmaceutical
cals Ltd and also BAPI Senior Vice President Ab- industry for the post-graduation phase.

ERD Additional Secretary Farid Aziz and Pro-
ject Director of SSGP, Dhaka University’s Law
Department Professor Dr Mohammad Towhidul
Islam and BUILD CEO Ferdaus Ara Begum also
spoke on the occasion.

THE PHARMA WORLD 31

SPOTLIGHT Post-LDC Era: What Awaits
Bangladesh Pharma Sector

Bangladesh is among very few countries Figure: Import of API (Organic
which were able to take advantage of LDC Chemicals: HS 29) by
waivers in view of WTO-TRIPS Agreement.
The waiver was first granted in 2001 at WTO-MC4 Bangladesh in FY2020-21
in Doha as part of the Doha WTO Ministerial de-
cision on TRIPS and Public Health. Malaysia 3% Korea 3%
Under the current trips agreement, drug mak- Singapore 5% Others 5%
ers in LDCs can produce any generic medicine China 34%
without having to follow the patent guidelines India 32%
until January 1, 2033, but the benefit is not appli-
cable for graduating LDCs such as Bangladesh. Import in FY2020-21 = 1050.1 million USD
The privilege is expected to end in 2026 when
Bangladesh is set to graduate into a middle- to this end has been in talks for decades but so
income country. Without an extension of TRIPS far there has been little progress.  
for the pharmaceutical sector, the government
will have to withdraw its control over medicine In the seminar, DCCI President Rizwan Rah-
imports, which will make the market more chal- man in his opening remarks said that after
lenging for small manufacturers.  Besides, com- graduation, Bangladesh would face a higher
panies will have to buy patents from a drug’s tariff regime, ranging from 8.0 per cent to 15 per
parent company to produce a generic version, cent, in the export market which might decline
which will ultimately increase the cost of pro- export earnings by 14.28 per cent - equivalent to
duction. US$5.73 billion. “Upon economic graduation, our
In order to avoid the looming hurdles, experts IP exemption benefit will be reduced beyond
at the seminar “Export of Pharmaceutical Sector
upon LDC graduation: Strategies & Way forward”
organized by Dhaka Chamber of Commerce &
Industry (DCCI), suggested that companies begin
producing raw materials for making medicines
or active pharmaceutical ingredients (API) local-
ly. Building an API industrial park in Munshiganj

exPort challeNges after ldc graduatioN

Bangladesh is set to graduate from
Least Developed Countries (LDCs) in 2026

major challeNges

Loss of duty-free, Loss of flexibility Loss of
quota-free in providing flexibility under

(DFQF) access export subsidy TRIPS
Currently 72% of Tk6,600 crore Pharmaceuticals

total export is subsidy recorded in industry to be
under DFQF FY21 impacted most

estimates of PossiBle exPort loss:
$6.38BN of Which $5.28B iN eu
talks oN for exteNded trade facilities for
5 years after 2026

32 THE PHARMA WORLD

Figure: Pharmaceuticals Export from Bangladesh ers can utilise the US market opportu-
nities, the value may cross $5 billion
200 120.00 within the next five to six years.

180 100.00 ABM Faruque, a professor of the
160 department of pharmaceuticals of the
University of Dhaka, also suggested
80.00 quickly opening API parks, a project for
140 which was taken in 2008 but could not
120 60.00 be implemented until now.

100 40.00 Although being ranked at 67th in the
global pharma export market last year,
80 20.00 in terms of API, Bangladesh is heavily
60 import-dependent. In FY21, the coun-
try’s API import amounted to $1050.1
0.00 million while the global API market is
40 $200 billion.
20 -20.00
Ahmad Kaikaus, principal secretary
0 -40.00 to the Prime Minister, said LDC gradu-
FY09 FY10 FY11 FY12 FY13 FY14 FY15 FY16 FY17 FY18 FY19 FY20 FY21 FY22 ation will be an opportunity for the
country even though there are some
Amount (In million USD) Growth Rate challenges to overcome.

2026 having no import restrictions,” he sources, and explore opportunities for Prosenjit Chakraborty, general man-
said. Mr Rahman said the pharmaceu- setting up joint ventures and encour- ager of Square Pharmaceuticals, sug-
tical sector might be affected by loss age contract manufacturing. The API gested launching negotiations with
of IP waiver, resulting in decline of ge- Park having the facility of CETP should the US for exporting more medicine to
neric and patented drugs production be operationalised as early as pos- the US defence services as an oppor-
and export share.Alongside, the pri- sible, he recommended. “Bangladesh tunity has been created in this regard.
vate sector is to be equipped and in- should take advantage of a compul- He also suggested launching negotia-
centivised on IP adoption for business sory licensing provision of the TRIPS tions with leaders of the Association of
development, he said. agreement by bringing in required South East Asian Nations as the trade
changes in the patent laws and drug bloc has taken some measures to only
The DCCI president also requested policies,” said Mustafizur Rahman. do business with medicine within
the government to consider various member countries.
policy reforms, including development Salman Fazlur Rahman, private in-
of pharmaceutical research and devel- dustry and investment adviser to the [Compiled from the deliberations in the
opment facilities and export market Prime Minister, said annual pharma- seminar organised by DCCI, July 23, 2022]
diversification. ceutical exports from Bangladesh will
cross $1 billion from the current $160
Presenting the keynote paper at the million within the next two to three
event, Professor Dr Mustafizur Rah- years as the door to US markets are
man, distinguished fellow at the Cen- open for certain local drug makers be-
tre for Policy Dialogue (CPD), suggested cause of their high level of compliance.
that pharmaceutical companies focus He also said if local drug manufactur-
on strong research, upskill human re-

Tk27,000cr Higehxeprehnedailttuhrceare

industry now Local Incorfeaagseedinpneoupmleber
demand Increased
To grow to
to be dependence
Tk1,00,000cr fuelled by on medicine

by 2030

lOcoovcneatrlr8mib5ua%rtkioent’s

likely

Gastric Cardiovascular Respiratory Nervous system Oncological Drugs that see
growth most

Export Exports grew Exports in $1.5bn annual Bangladeshi firms Focus on higher
potential 3latsitmdeescaodveer F$Y12619m bexyp2o0r3t0s expected mtaargrkeet tdseveloped dvarulugesprescription

THE PHARMA WORLD 33



“Laser surgery is the present and INTERVIEW
future of dermatosurgical solution”

Prof. Dr. M. U. Kabir Chowdhury that, if one member is infected with such disease all must
Professor & Head be checked and treated if necessary to control infection for
Dept. of Dermatology the others.
M.H. Samorita Hospital and
Medical College How do you determine when a mole needs
Chairman & Chief Consultant further examination for skin cancer?
National Skin Centre, Dhaka Mole or nevus needs clinical checking first to diagnose
whether it is precancerous or cancerous. ABCDE formula
What types of skin diseases which are as follows: Asymmetry, Border, Color, Diameter
are prevalent in Bangladesh? and Evolving of existing mole which is cardinal sign of
melanoma. Dermoscopy or biopsy with histopathology can
Contagious skin diseases are confirm the lesion whether malignant or nonmalignant.
prevalent in Bangladesh.
Can acne also appear on a skin that has other problems
As Bangladesh is a tropical such as dermatitis, psoriasis or eczema? What is the
country, are contagious skin treatment in such cases where various conditions
diseases like fungal and can sometimes be “conflicting” with each other?
parasitic infections more Usually acne appears on cleaned and oily skin mainly face
common in this weather? though it may involve trunk and arms. In some cases acne
What is your suggestion may be associated with seborrheic dermatitis. Proper di-
to prevent this? agnosis of dermatitis, psoriasis or eczema can assure any
conflict or diagnostic dilemma. In these cases we can go
Prevention of contagious skin for proper diagnosis and exact treatment. So, no chance
diseases are crucial for safety of conflict.
of family and the surroundings.
Fungal infection of skin are very What causes eczema? Can it be cured? What can patients
much prevalent in this weather. do to prevent and soothe their eczema flare ups?
Cleanliness is the key to fungal Eczema is an allergic dermatitis which may be contact
and parasitic infection preven- dermatitis. In this case, if we can trace the contact or
tion. To prevent fungal and par- cause, eczema is curable. But, mostly it is a controllable
asitic diseases we need a very disease. Avoidance of the cause of eczema is the best
strong school health program prevention. It may flare due to infections or irritants of
including madrasha. Most of the environment or diseases like diabetes.
ectoparasitic diseases come in
contact with minor school boys Cryosurgery is a fairly new concept in our country.
and girls of which scabies is the Could you tell us more about the procedure? What
most common. My suggestions conditions can be treated with cryosurgery?
for the society and the family is Cryosurgery is not a new concept in dermatology as I have
done cryosurgery in St. Thomas Hospital, London more
than 40 years back. Cryosurgery is done by cryogen spray
which contains liquid nitrogen at -198 degree centigrade.
All sorts of viral warts, molluscum contagiosum, basal cell
carcinoma, some kind of melanoma, leukoplakia and so
many tiny skin conditions can be treated with cryosurgery.

Are there any innovations on the horizon that you feel
are particularly noteworthy in the field of dermatology?

Laser surgery is the latest and most innovative horizon
which is noteworthy in the field of dermatology. This is
present and future of dermatosurgical solution.

THE PHARMA WORLD 35



Early diagnosis and treatment is crucial INTERVIEW
to reduce the burden of skin diseases

Prof. Dr. M.N. Huda Please tell us in brief about the prevalence and
risk factors for sexually transmitted diseases
Chairman (STDs) in Bangladesh. What can be done to increase
awareness about STDs among common people?
Laser Aesthetics (Pvt.) Limited, Dhaka
In Bangladesh, recent studies show the increase rate of
What types of skin diseases STDs in last 10 years is about 12%. The risk factor are un-
are prevalent in Bangladesh? protected sex with sex worker, no regular checkup and
treatment facilities in brothel houses, and illegal sex
Thank you for your question. As business in hotel and rest houses. Increasing awareness
we know Bangladesh is a tropi- by electronics media and social organization to the mass
cal country and temperature is public is vital for prevention.
comparatively high round the
year. Due to this hot and humid Although there has been low prevalence of AIDS in our
climate, different fungal, para- country, recent evidence shows rise in cases. Why is
sitic and bacterial diseases are that so? Who are the key groups vulnerable to HIV?
common. Common skin diseas-
es are superfacial, fungal and Our common people are not aware about AIDS or HIV in-
parasitic infection. Bacterial in- fection. Still our prevalence rate is not so high due to reli-
fection are also common in chil- gious believe and bindings. The people who practice un-
dren, and aged diabetic people. protected sex, sex worker and IV drug abusers are more
Except this fungal, parasitic and vulnerable to HIV.
bacterial infection, other skin
diseases like acne, eczema, pso- Is Herpes Simplex dangerous long term?
riasis and vitiligo are common How is it Treated? Is it curable?
skin problem.
Actually, there is no virocidal drug still today In the world.
As Bangladesh is a tropical The drug we are using are virostatic. So there is no cur-
country, are contagious able treatment of any viral diseases. We can control the
skin diseases like fungal viral diseases by virostatic drugs and symptomatic treat-
and parasitic infections ment. In some rare cases of herpes simplex viral infection
more common in this in female, there is a chance of cervical cancer.
weather? What is your
suggestion to prevent this? What causes vitiligo? Are there any trigger
factors for onset of vitiligo? Is there any
In our country common prob- permanent solution for vitiligo?
lem is over population, poverty
and living condition. So, I sug- Exact cause of vitiligo is not known. It is a autoimmune
gest to reduce the population disease. There is a genetic predisposition, but only in 20%
growth by expansion of family causes. There are lot of triggering factors including family
planning programme, educate history, hormonal disorders, over weight, mental stress,
the people to maintain personal etc. Yes in more than 75% cases it is curable. It need early
hygiene and avoid the contact diagnosis and treatment.
with infected persons.
Despite the efforts to eliminate leprosy as a public
health threat, Bangladesh’s leprosy burden is still
very high. Why is that so? What can be done to prevent
permanent damage in patients with leprosy?

The prevalent rate of Leprosy is very low recently, com-
paring of 20 years back, Leprosy is treatable and curable
with multi drug therapy (MDT), suggested by World Health
Organization (WHO). Early diagnosis and treatment is cru-
cial to prevent , cure as well as reduce the burden of so-
ciety of skin diseases.

Thank you again.

THE PHARMA WORLD 37

“We have to dream, and we have
to cultivate the capacity for
innovation and invention”

Ahmed Kamrul Alam As an integral part of DBL Pharma ticals Ltd., DBL Pharma Inc., and DBL
Executive Director, Business Operations Ltd. – could you please introduce Healthcare.
DBL Pharmaceuticals Limited the company to our readers?
DBL Pharma is a relatively new
DBL pharma always DBL Pharmaceuticals limited is a sis- player in the pharma arena. What
prioritises the ter concern of DBL group. The group plans do you have to consolidate
development of the started its journey in 1991 and evolved its position to enable it to leave a
newbies. Starting into a diversified conglomerate. Since footprint in the pharma landscape?
from medical the inception of their journey, the
representatives to the main strength and focus of the DBL It is rather easier to start something,
top CEO, everyone here group has been textile, garments, and but sustaining it long time is the real
is always in a learning/ more recently, the ceramic industries. challenge. Pharmaceutical products
training phase. We DBL Group has also made a name for deal with patients’ lives. So the qual-
strive for continuous itself in semiconductor designing, ity of the product is of utmost im-
development and dredging, printing and packaging, etc. portance. However, maintaining the
believe that progress When there was a need to diversify, quality is even more crucial. Com-
will lead to perfection. DBL focused on humanitarian causes municating the quality perceptions
and wanted to do something for the among the physicians and patients
patients of our country. This is how is something we’ve been working on
DBL pharma was born. since day one. So, there’s zero toler-
ance and we leave no scope for de-
DBL group has now grown into a viation when it comes to quality. Every
big family of 45,000 people and the single tablet, every drop of syrup of
business value has also grown more DBL pharma will have that valid-
than 870 million US dollars. ity and reliability in perceived quality
and true belief. This is how we want to
We have a vision to also grab vari- leave our marks.
ous aspects of the pharma industries,
albeit slowly, but steadily. The aspect We are concentrating on three an-
where we want to create a differ- gles—physicians, patients and prod-
ence—many may not know—is that ucts. We can truly provide a complete
DBL pharma has already been mar- healthcare service by integrating and
keting its products to the US market coordinating these three pillars of our
through a contract manufacturing focus. Without any of these pillars,
site. We have a subsidiary company, healthcare service, as a whole, would
DBL Pharma Incorporation. We have not be able to stand. So, our focus is
two USFDA-approved formulations. not only on the physicians, not only
In the methocarbamol generic tab- on the patients, not only on the prod-
let market in the United States, DBL ucts, but on all three of these aspects
Pharma Inc. is in the 2nd position. simultaneously and equally.

Aside from the core pharmaceuti- You have gradually taken positions
cal manufacturing, we have another of increasing responsibility
endeavor, which is DBL Healthcare, over more than two decades
focused on finished product importa- in Marketing. What would you
tion. DBL has imported large varieties highlight as the main specificities of
of European dermo-cosmetics brands DBL compared to other companies?
and products, FrezyDerm being one of
them, which is the number one der- At DBL Pharma, we don’t see it only as
mo-cosmetic brand in Greece. a business. Yes, of course there would
be a corporate environment and
So, I would say, to introduce DBL practices, but at the end of the day,
pharma—it is a three-unit entity
comprised of local DBL Pharmaceu-

38 THE PHARMA WORLD

our emphasis would always be on doing what a nuclear family nowadays, children are not FACE TO FACE
is expected of us and fulfilling our individual able to go play outside and be physically active
responsibilities. The very core of our value is anymore. This contributes to early obesity and
the “people” — Human Resource Development, other changes in disease patterns. Emergence
good people, motivated people. We try to de- of technology like cell phones is contributing
velop each and every one of our people from to an exponential increase in screen-time. As a
day one, so that they can deliver their best at result, we now see more and more cases of CNS
all times. I will definitely talk about the chal- disorders. Mental anxiety, stress, psychological
lenges in the industry later in this talk. How- issues, ADHD, depression, schizophrenia etc.
ever, I’ll briefly touch up something right now, are rising. The thing is mental health often re-
that is, the lack of skilled manpower in this mains ignored. So, we must focus here as well.
industry. We may have many graduates, and
post-graduate students, but when they enter Secondly, I would like to address automa-
the job sector as employees, we find them very tion. There has been huge changes with respect
underprepared. DBL pharma always prioritises to automation, something which the phar-
the development of the newbies. Starting from maceutical industry relies on heavily — from
medical representatives to the top CEO, every- pharmaceutical manufacturing process to the
one here is always in a learning/training phase. printing and design for promotional materials
We strive for continuous development and be- —automation is everywhere. Our productivity
lieve that progress will lead to perfection. has increased, we can achieve much more in a
lesser amount of time.
What in your opinion, is the key to
establish branding of a product? Thirdly, there has been a change in marketing
strategy. For example, it has become very diffi-
There are many textbook definitions of “Brand- cult to provide a focused time for the custom-
ing”. But, to me, it is not very critical. We have to ers. Doctors’ visiting time is not as elaborate as
be different. The aspect where we can create a it used to be. The physicians have become very
differentiation is our branding. For example, there busy as they have to manage patients, other ac-
are many paracetamols out there in the market. tivities and events.
Why would doctors choose my paracetamol, what
can make my paracetamol unique among all the Fourthly, we have learned a lot from the
others—it might be quality, it might be good COVID pandemic. During that period, the overall
packaging, it might be pricing strategy, might be pharmaceutical promotional activities and nor-
promotional strategy—so, we need some kind of mal corporate activities were halted physically.
variation, a distinct feature unlike anyone else. Everything shifted to online virtual platform.
The more unique feature you can provide, the We are carrying that practice even today. We are
better brand you’ll be able to create. doing various clinical events virtually with the
physicians, we are doing many corporate meet-
As an accomplished pharmaceutical ings virtually.
professional, how do you evaluate the changes
in trends in the pharmaceutical industry Patients are also nowadays more learned and
during your long 27 years of experience? have more liberty to choose their physicians and
brands of their medication. However, they are
There have been lots of changes. I have wit- also more exposed to misinformation and disin-
nessed a paradigm shift. formation in this era of information overload. As
we’ve seen during the pandemic, the tendency
Firstly, the disease pattern has changed. of patients to self-medicate has increased and
Non-communicable diseases are becoming so have the adverse drug reactions. So, there
more and more prevalent, compared to the has been a paradigm shift in the industry.
past, when the main fight was against infec-
tious diseases. Hypertension, diabetes, cancer, What are some of the challenges the
heart disease, and obesity are rising alarmingly. industry is facing now and what are the
So, when disease pattern changes, the phar- potential solutions, in your opinion?
maceutical industry is also bound to change.
Bangladesh is going through an economic tran- The first thing I would like to mention is R&D.
sition— from LDC, we are slowly moving toward Yes, we are good at formulations, we are good at
a developing nation. Our economic strength is finished products, we are exporting, and we are
increasing; hence, social structure is also ex- 98-99% self-sufficient in medicines. But, keep in
periencing a change. All these are impacting mind, all these are finished products. But when
the pharma industry as well. For example, in it comes to the research behind the products,
the real research and development, we are lag-
ging behind. We should invest more in R&D to

THE PHARMA WORLD 39

turn this weakness into our strength. off-patent medications we have. When We value your opinion
Then comes API— we still have a long the new patent would be applied in and would like you to
way to go in terms of access and local the future, we may have to pay more share it with us.This
production of high-quality excipients to import the new molecules. By then, would help us to deliver
or raw materials. Next, I would men- we would have the financial means to
tion skilled manpower again—from cover the additional expense of intro- a more enriched
production, and quality control to ducing the new medication. On the THE PHARMA WORLD
marketing and HR— everywhere we other hand, even if we face any delay
need skilled manpower. Many of the in acquiring the new drug, I believe, we to you.
fresh graduates lack or are unable to will have numerous alternate options
acquire the skills they need to con- available for treating the condition. 51, Kalabagan 1st Lane
tribute to their specific duties. This is Tel: 88-02-58155677
also a major challenge, in my opinion. Our LDC graduations has some op-
portunities as well. I’ll explain why. We 677395919
The pharmaceutical sector is a are experts in formulation, there is
very technology-centered industry. very good research being done in top
There are many independent seg- universities; All we need to do is prior-
ments involved. For example, there itize R&D and API production. Rather
is some good research being done in than increasing investment in bringing
universities; the industry is also do- new molecules, why can’t we imagine
ing very good work. So, if there were Bangladesh being able to patent novel
any collaboration or synchronization medicines or formulations? We’ll be
between academia and the industry, able to enjoy the patents when other
on any platform, it would help us a lot countries will buy from us. So, we have
in the long run. On the other hand, to dream, and we have to cultivate the
the universities could also build up capacity for innovation and invention.
their students and help them develop It is very much possible if we do our
skills specific to the needs of the dif- homework diligently.
ferent aspects of the industry; it could
be done by updating the curriculum You were instrumental in propelling
or by providing specific training. This Square Pharmaceuticals to the top
would increase the employability of of the industry, and now you’ve
the graduates. joined a brand-new company.
How would you translate your
Similarly, the industry is uninformed success in this new challenge?
of institutions’ research scopes. If we
were aware of the capacity and scopes, My success would be when I am able
we could easily utilise this to our ad- to effectively implement my experi-
vantage while providing this as mas- ence in the new setting. I always have
ter’s thesis. The students also get to this intent and this drive. So, there’s no
understand a real-life experience in- reason not to succeed. I must have had
volving analysis and R&D. This could be a foolproof policy to be able to survive
our “one stop shop” for innovation. To- there for 27 years. So, I can definitely
day, academic institutions and leading do the same here. As I’ve said before,
pharmaceutical companies throughout that DBL is now fully focused on its
the world both use academic-industri- people, which is, in my opinion, the
al relationships as a part of their inte- biggest asset. Everything else will fall
grated development strategies. in place with the right strategy, integ-
rity and motivation. There shouldn’t be
How do you evaluate the too many obstacles in working in the
opportunities and challenges green-field area. You have to remem-
of Bangladesh pharma sector ber that there’s no alternative to learn-
after its graduation from LDC? ing, hard work, and perseverance. Also,
Where do you see the industry it is not a one-man show. The team-
in the next 10 years? work allowed me to accomplish what
I have. So, if I’m surrounded by like-
Regarding LDC graduation, it is not minded people and work at the same
a big headache or any threat for me. pace towards the same goal, success
Because most of our illnesses are will follow here as well.
treatable with the already available,

40 THE PHARMA WORLD

Antimicrobial-resistant genes affect birth outcomes AMR

Researchers studied the rectal microbiota of 2,931 neonates (up to 60 days of life) with
clinical signs of sepsis and of 15,217 mothers screening for antimicrobial resistant genes
(ARGs). The identified carbapenemase-positive bacteria showed a high diversity of
bacterial species (57 distinct species/genera), exhibiting resistance to most antibiotics
tested. Genomic analysis of the most commonly found isolates revealed close relation-
ships between isolates from different samples, indicating possible bacteria transmission
between neonates, and neonates and mothers. The presence of ARGs was a predictor of
neonatal sepsis and adverse birth outcomes.

LMIC need a bottom-up view Pharmacists can
of AMR transmission lead antimicrobial
stewardship
High-risk AMR transmission points in Low and middle-in- programs (ASPs) 
come countries settings, such as urban spaces and food-
animal production settings, are often addressed with To evaluate the effectiveness of
top-down and infrastructure-dependent interventions to a pharmacist-led ASP in a hospi-
combat AMR. However, these LMIC settings outside of hos- tal without an infectious disease
pitals require a combination of strong regulatory oversight physician, a prospective quasi-
and bottom-up AMR-containment approaches. Greater ac- experimental study was executed,
cess to technological innovations must be promoted to help implementing an ASP in a 194-bed
AMR containment and prevention in low-resource settings. hospital in Spain. Researchers
evaluated changes in antimicro-
Antimicrobial-resistant genes bial use between pre-and post-
affect birth outcomes intervention periods.

Researchers studied the rectal microbiota of 2,931 neo- A total of 847 antimicrobial
nates with clinical signs of sepsis and of 15,217 mothers pharmacist interventions (PIs)
screening for antimicrobial resistant genes. The identified were proposed (88.3% were ac-
carbapenemase-positive bacteria showed a high diversity cepted), and direct expenditure
of bacterial species, exhibiting resistance to most antibiot- on antibiotics decreased sig-
ics tested. Genomic analysis of the most commonly found nificantly. Discontinuation due to
isolates revealed close relationships between isolates excessive duration was the most
from different samples, indicating possible bacteria trans- frequently performed PI (23.4%)
mission between neonates, and neonates and mothers. with most PIs classified as hav-
The presence of ARGs was a predictor of neonatal sepsis ing a major or moderate clinical
and adverse birth outcomes. impact.

People with The necessity for multiple courses or long-term use of antibiotics, repeated
chronic liver hospitalizations, and complicated procedures put patients with cirrhosis at el-
disease are evated risk of antimicrobial-resistant (AMR) infections. One-third of infections
at increased in patients with cirrhosis is estimated to be due to multidrug-resistant bac-
risk of AMR teria. Given the variations multidrug resistance prevalence in different world
infections regions, treatment should be based on local microbiological epidemiology, in-
stead of relying on broad international recommendations. There is a need for
both antimicrobial stewardship programs and investigation of non-antibiotic
approaches for infection prophylaxis in patients with cirrhosis.

THE PHARMA WORLD 41



“Biologics are glimpses of hope INTERVIEW
in some recalcitrant skin diseases
like atopic dermatitis, autoimmune
bullous diseases, psoriasis etc.”

Prof. Dr. Md. Qamrul Hassan Jaigirdar What types of Skin diseases are prevalent in Bangladesh?
Professor & Chairman
Department of Dermatology & The common skin diseases in Bangladesh are: Scabies,
Venereology, BSMMU, Dhaka fungal infections, eczematous skin diseases, psoriasis,
vitiligo, acne vulgaris, alopecia, melasma, etc.
Dermatology is a
rising subject. In As Bangladesh is a tropical country, are
case of research contagious skin diseases like fungal & Parasitic
work, many clinical infections more common in this weather? What
trials can be done are your suggestions to prevent this?
in chronic diseases
like vitiligo, psoriasis, Yes, contagious skin diseases like fungal & parasitic infec-
Lichen planus. tions are more common in this weather because in hot
weather there is excessive sweating which that acts as a
predisposing factor for such infections. Moreover, as most
of the people of our country live in overcrowded house-
holds, contagious skin infections are widespread. Nurser-
ies, hostels, different sports activities that involve close
contact, and touching objects that house Scabies and
fungal organisms, wet, damp garments/undergarments,
lack of personal hygiene awareness, etc. contribute to the
spreading of fungal & parasitic diseases like Scabies to
transmit rapidly.

To prevent the transmission of these infections some
measures must be taken.

Patients should avoid sharing garments, linen and tow-
els including shower room napkins. All the garments, un-
dergarments, and socks must be thoroughly washed daily
in hot water, sun-dried or iron pressed on the reverse side.
Simultaneous treatment of family members of the affected
person is crucial, particularly for scabies. Also, all close con-
tact of infected persons and intimate contact with partners
should be avoided during active infection. Patients need
to be advised to keep the skin, especially body folds, and
finger and toe web spaces dry. Regular bathing, at least 2
times throughout the day is advised for those who perspire
profusely. Nails should be trimmed to avoid the spread of
infection. Shared surfaces such as gym equipment & mats
should be regularly disinfected. Sandals or flip-flops in the
locker room need to be worn instead of walking barefoot-
ed. Tight clothing and shoes should be avoided.

Regarding fungal infection, the patient should be coun-
seled regarding the nature of the disease. The patient
should be warned against using steroid cream. It will
worsen the severity. Infected person should avoid close
contact with other family members. The patient should
not stop antifungal medication without consultation with
a dermatologist.

THE PHARMA WORLD 43



How important is it to recognize the type of acne for its plaque psoriasis and often psoriatic arthritis.
treatment? And what are the differences, for example,
treatments for comedonal acne compared to nodules? Clinical Feature: There is formation of pus at the edge of psori-
atic plaques on palms or periungual skin becomes erythema-
Yes, it is very important to recognize the type of acne for its tous before the appearance of pus. Pruritus & intense burning
treatment. Though Acne is primarily a disease of adoles- are often present’ Geographic or fissured tongue may occur.
cents with 85% of teenagers affected to some degree (15-18)
of both genders. Generally, resolution occurs before 25 in Provoking factors: Episodes are provoked by with drawl of
both sexes. About 12% of women & 3% of men will continue systemic corticosteroids. It may also occur due to some drugs-
to have acne until they reach 44. Acne may also begin in iodides, coal tar, terbinafine, minocycline, acetazolamide, sa-
20-35 year old women who have not experienced teenage licylates. Associated Features may be fever, erythroderma,
acne. Neonatal acne is a common condition developing af- hypocalcemia, cachexia’ complications: ARDS’ pneumonia,
ter birth. PCOS associated acne, acne conglobata, SAPHO & congestive heart failure, hepatitis, etc.
related syndromes, acne fulminans, acne keloidalis, tropi-
cal acne, etc. have different pathogenesis & presentation. Treatment: Acitretin is the drug of choice (25-50mg daily).
Accordingly, their treatment varies. So it is important to cat-
egorize the acne types. Differential diagnosis: Subcorneal pustular Dermatosis,
Acute generalised exanthematous pustulosis (AGEP).
There is great variability in age of onset and resolution.
Acne vulgaris is a chronic inflammatory disease character- What causes vitiligo? Are there any trigger
ized by comedones, papules, pustules, nodules and often factors for onset of vitiligo? Is there any
scars. Comedone is the primary lesion of acne, occurring permanent solution for vitiligo?
in mild variety. Usually treated with topical retinoid with or
without physical extraction (First line). Alternatively, benzoyl Vitiligo is considered as an autoimmune-acquired dis-
peroxide, salicylic acid, and azelaic acid are used (Second ease. However, different theories exist regarding etiology
line). Nodular acne often leads to severe type by enlarging to as mutations in the autoimmune regulator gene, defects
coalescence plaques, that are indurated and fluctuant, con- of melanocyte adhesion, neurogenic damage, biochemical
taining sinus tracts often leading to scarring. Treatment con- damage, autocytotoxicity etc. Triggering factors are physical
sists of oral Isotretinoin, oral antibiotic with topical retinoid trauma, sunburn, psychological stress, pregnancy, contra-
and benzoyl peroxide. In case of women, spironolactone ceptive, and certain surgical procedures etc.
with oral contraceptive with topical retinoid; with or with-
out oral contraceptive and/or benzoyl peroxide. In women, Treatment response depends on type of vitiligo. There
combination therapy of spironolactone, oral contraceptives, are many types of vitiligo:
topical retinoid and oral antibiotic can be another option.
Nodular acne has a tendency to form scar. If there is forma- 1. Localized- a. Focal b. Segmental
tion of scar then some surgical modalities can be done. Like c. Mucosal
chemical peel, microdermabrasion, subcision, fractional &
non-fractional lasers. 2. Generalized- a. Acrofacial b. Vulgaris c. Universalis d.
Mixed
Can acne also appear on skin with other problems
such as dermatitis, psoriasis or eczema? What is the In localized vitiligo involving less than 10% of body surface
treatment in such cases where various conditions area, topical calcineurin inhibition plays a significant role.
can sometimes be “conflicting” with each other? Segmental vitiligo persistent for 12 months is very difficult
to treat.
Treatment of acne is not much conflicting with dermatitis,
psoriasis and eczema, we have to be careful regarding the use In Generalized vitiligo, acrofacial & mucosal vitiligo,
of steroids in eczema or dermatitis with concomitant acne, as treatment response is poor. In these cases, phototherapy
acne can be aggravated by the use of steroid. If a patient with or Janus kinase Inhibitor are advised but the response is
psoriasis and acne is treated methotrexate and antibiotic variable. There is no permanent solution of vitiligo. Howev-
there will be no drug interaction. But a patient with pustular er, depending on the types, different promising treatment
psoriasis is usually treated with acitretin. In that case, isotreti- options are available.
noin should not be used as both are vitamin A derivatives and
concomitant use of acitretin & isotretinoin will cause over- Are there any innovations on the horizon that you feel,
dose toxicity. are particularly noteworthy in the field of dermatology?

Although many of us are familiar with plaque Yes, of course. Dermatology is a rising subject. In case of
psoriasis, GPP or generalized pustular psoriasis is research work, many clinical trials can be done in chronic
not something that many of us come across. Please diseases like vitiligo, psoriasis, Lichen planus. Moreover,
tell us, what is GPP and its treatment thereof? in case of cutaneous surgery, dermatologists can play an
important role. In case of vitiligo surgery, acne scar sur-
It is a type of psoriasis where the patient has a history of gery, nail surgery, there are many dermatological innova-
tions. In case of alopecia, platelet rich plasma can be an
innovative option. Biologics are glimpses of hope in some
recalcitrant skin diseases like atopic dermatitis, autoim-
mune bullous diseases, psoriasis and also for some con-
nective tissue diseases.

THE PHARMA WORLD 45



“Specialty of Dermatology is one of the most INTERVIEW
flourishing subject of medical science”

Prof. Dr. Rashed Mohammad Khan  Can high blood sugar level cause skin problems?
Professor & Head What are some skin conditions linked to
Department of Dermatology & diabetes and how are they managed?
Venereology, DMCH High blood sugar level causes several skin problems. Some
skin conditions linked to diabetes are generalized itching,
What types of skin diseases bacterial and fungal infections of skin, delayed wound heal-
are prevalent in Bangladesh? ing, diabetic foot, diabetic bullae, diabetic dermopathy.
other skin conditions associated with diabetes are kyrle’s
Common skin diseases which disease, eruptive xanthoma, skin tag, lipoatrophy, acantho-
are prevalent in Bangladesh sis nigricans.
are superficial fungal infections
(dermatophytosis), scabies, ec- High blood sugar related skin problems are managed by
zema, psoriasis, vitiligo, acne strict control of blood sugar, early treatment and lifestyle
vulgaris, occupational dermati- modification.
tis, bacterial skin diseases, viral
infections of skin, skin tuber- What causes eczema or atopic dermatitis? Can
culosis, leprosy, melasma, and it be cured? What can patients do to prevent
skin manifestations of sexually and sooth their eczema flare ups?
transmitted diseases. Multiple factors associated with eczema or atopic dermati-
tis but most common factors are
As Bangladesh is a tropical
country, are contagious skin l Genetic e.g. FLG gene mutation l Immunologic l Envi-
diseases like fungal and ronmental e. g. Food allergy and aeroallergens, stress,
parasitic infections more heat and sweating
common in this weather?
What is your suggestion Atopic dermatitis is not a curable disease but can be well-
to prevent this? controlled by proper counselling and treatment. To prevent
flare ups patient should moisturize daily, especially immedi-
As a tropical country, contagious ately after bathing. This may be with petrolatum or a petro-
fungal skin diseases like Derma- latum-based product, an oil based product or a moisturizer
tophytosis and parasitic infec- that contains the essential lipids of the epidermal barrier.
tions like scabies are common
in Bangladesh. To prevent these Can systemic therapies help to permanently change
diseases patients have to main- the appearance of the skin in atopic dermatitis?
tain proper hygiene e.g. regu- No systemic therapy can permanently cure atopic dermati-
lar bath, wear loose and cotton tis but can reduce the intensity of symptoms.
cloths, avoid cloth sharing, seek
proper treatment by qualified What causes vitiligo? Are there any trigger factors for onset
dermatologist, simultaneous of vitiligo? Is there any permanent solution for vitiligo?
treatment of other family mem- Vitiligo is an autoimmune disease. There are some factors
bers and avoid OTC drugs. associated with vitiligo such as l Genetic l Neural l Oxi-
dative stress

Some triggering factors related to the onset of vitiligo are
trauma like physical, chemical and sun exposure. There is
no permanent solution for vitiligo but many treatment mo-
dalities may stop the progression and repigmentation of
the depigmented areas.

Are there any innovations on the horizon that you feel,
are particularly noteworthy in the field of dermatology?
Specialty of dermatology is one of the most flourishing
subject of medical science. We have developed multiple
subspecialities like dermatosurgery, aesthetic dermatology,
LASER treatment and photobiology.

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“Biologics have opened newer INTERVIEW
horizon in the field of dermatology
which includes rarest diseases
even with genetic etiology”

Prof. Dr. M Mujibul Hoque As Bangladesh is a tropical country, are
Ex. Professor & Head contagious skin diseases like fungal and parasitic
Department of Dermatology & infections more common in this weather?
Venerology, DMCH What is your suggestion to prevent this?

What types of skin diseases Fungi can produce harmful effects by producing myco-
are prevalent in Bangladesh? toxin, by evoking allergic reactions or by tissue infection.

It has been observed that, of all Tinea corporis is a communicable fungal infection, trans-
patients in out- patient depart- mitted by intimate personal contact, through sharing brush-
ment of general hospitals, one es, combs, towel, bed linen etc.
in every four patient is suffering
from skin disease. The patient In addition of systemic therapy, those affected should
demographic consists majorly of be counseled not to share caps, combs, toys etc.
poor people living in overcrowd-
ed slums, with malnutrition, Trauma, maceration and increased hydration of skin
lower income and low literacy make the inroad for pathogenic fungi. The pathogenesis
rate. Lack of Proper hygiene in of dermatophytosis is not well understood. Protein defi-
slums contributes to recurrent ciency has been blamed along with Vitamin A deficiency
scabies, superficial fungal in- as predisposing factor to dermatophyte infection. A good
fection, pyoderma, pediculosis, number of antifungal drugs have been invented but none
parasitic and viral infections. including topical therapy are expectedly efficacious. Anti-
fungal shampoo is helpful.
The Pattern of disease is
slightly different in a more well- Living in warm climate, having contact with infected
off community. They are gener- persons or animals, sharing clothing, bedding or towels
ally sufferers of eczema, acne, with someone with fungal infections. Because fungal in-
vitiligo, pigmentary changes, fection is very contagious, clothing including underwear
psoriasis, lichen planus and ve- should be changed every day.
nereal diseases.
Heat above 110⁰ F is effective at killing ring worm
Cases of Skin Tuberculosis spores. No bleach will be necessary if cloths are dried
and leprosy has come down to at such temperature, but with fungal infections nothing
great proportions. Cases of lep- works 100%.
rosy however are still prevalent
in some areas. Plasma membrane  lipids  are important regulators
of  fungal  pathogenicity. It is hypothesized that washing
the lipids from the skin’s surface prevent fungal growth.

Improvement of demographic and climatic environ-
ment is beneficial. Ensuring essential food, education,
medical facilities, employment, improvement of hygienic
condition in slums, illiteracy may play role in lowering
these diseases.

Please tell us in brief about the prevalence and
risk factors for sexually transmitted diseases
(STDs) in Bangladesh. What can be done to increase
awareness about STDs among common people?

The overall prevalence of Neisseria gonorrhoea, Chlamydia
trachomatis, Trichomonas vaginalis and Treponema palli-
dum infection was 0.5%, 1.9%, 2.0% and 2.9% respectably.

Overall 35% women had antibody to Hepatitis B core
antigen, 0.9% had HcV and 12% HSV infection. Little in-

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50 THE PHARMA WORLD