SurterraProductandDosingGuide

Product
&
Naturally-derived therapeutic cannabinoids and terpenes
Dosing Guide


We do things differently
At Surterra Wellness, our unique formulations offer a combination of Cannabidiol (CBD) and Tetrahydrocannabinol (THC) in a variety of ratios designed to address different patient needs. Our targeted formulations provide the opportunity to find the right medication to deliver the best results for your patients.
For more information visit surterra.com
These statements have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease.


Low-THC Cannabis and Medical Marijuana
Medical marijuana is available in the state of Florida pursuant to Section 381.986, Florida Statues and Article X, Section 29, Florida Constitution and can be purchased in a variety of formulations and routes of administration at state-registered dispensaries. Low-THC cannabis and medical marijuana are forms of plant-based medicine that can be used to effectively manage symptoms for many medical conditions while enhancing overall wellness and quality of life. This Physician Reference Booklet is intended to be a resource for medical personnel to guide you in determining the right formulation, cannabinoid ratio, and route of administration to best meet your patient’s individualized needs.
Low-THC Cannabis:
Low-THC Cannabis contains very low amounts of the psychoactive component tetrahydrocannabinol (THC). Low-THC Cannabis is specifically characterized as having less than 0.8% THC and greater than 10% cannabidiol (CBD). With low-THC cannabis, the medication is intended to deliver the benefits of medical cannabinoids while minimizing the intoxicating effects of THC.
Medical Marijuana:
Medical Marijuana contains larger amounts of THC, specifically, more than 0.8% of THC, in addition to CBD, terpenes, and other cannabinoids. Medical marijuana is intended to deliver the benefits of medical cannabinoids in combination with THC, leveraging the effects of THC to assist patients in managing pain, discomfort, and mood.
Surterra | Cannabis and Medical Marijuana 1
Cannabis and Medical Marijuana


The Endocannabinoid System
The Endocannabinoid System (ECS) is a complex network of molecules and receptors that consists of two primary phytocannabinoids receptors: CB1 and CB2 receptors. CB1 receptors are most abundant in the central nervous system and the CB2 receptors are most abundant in the peripheral nervous system, the circulatory system and the digestive system. Endocannabinoids and phytocannabinoids interact with the CB1 and CB2 receptors to regulate many physiological processes including:
• Appetite
• Blood Pressure • Inflammation • Memory
• Mood
• Pain Sensation • Sleep
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Surterra | Cannabis and Medical Marijuana
Nervous Respiratory System System
Circulatory Digestive System System
The Endocannabinoid System


Cannabis
Cannabis is a complex plant that has been used medicinally world-wide for over a thousand years. Many clinical studies have been completed in the United States and in international markets, yet, there is much more to learn about the medicinal properties of cannabis and the quest for modern research on cannabis continues to grow.
Cannabinoids:
Cannabis contains over 400 chemical compounds, including cannabinoids, which give the cannabis plant its medical and recreational properties. The marijuana plant produces over 100 different cannabinoids, including THC and CBD, which are the most well-known and most investigated cannabinoids. CBD is known for its relaxing and restorative effects while THC is known for pain relief and promoting mental uplift.
Terpenes:
Terpenes are naturally occurring oils found in cannabis and commonly used herbs, spices, and fruits. Terpenes contribute to the effects of cannabinoids by enhancing and balancing out the overall effects of the medication. When it comes to cannabis, terpenes are the real drivers behind the differences between strains and cannabis varieties. For example, Indica strains which are known for their relaxing effects contain terpenes with calming properties, while Sativa strains contain terpenes that contribute to an uplifting and energizing effect. Surterra Wellness creates unique terpene profiles in combination with CBD and THC ratios to create unique formulations, delivering targeted effects.
Surterra | Cannabis and Medical Marijuana 3
Cannabis and Medical Marijuana


Terpene Profiles
4 Surterra | Cannabis and Medical Marijuana


Surterra Wellness Product Comparison Effects Spanning from Sedation to Uplifting:
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene
Black pepper, cloves
Anti-inlammatory, improved sleep
Eucalyptol2
Eucalyptus, rosemary, ginger
Anti-fungal, anti-inlammatory
Humulene
Cloves, basil, hops
Anti-bacterial, anti-inlammatory
d-Limonene
Fruit rinds, peppermint
Anxiety relief, stress relief
Linalool
Lavender, citrus
Calming, sedation
b-Myrcene
Mango, lemongrass, thyme
Relaxation, sedation
a-Pinene
Pine needles, rosemary, dill
Alertness, memory
Terpineol
Lilac, pine trees, lime blossoms
Calming, sedation
Surterra | Cannabis and Medical Marijuana 5
Cannabis and Medical Marijuana


Synergistic Effects
CBD, THC, and terpenes work together in the body in ways that influence the effects of one another. For example, CBD may reduce the euphoric effects of THC while the terpene myrcene may enhance the analgesic effects of THC. These synergies between CBD, THC, and terpenes are often referred to as “The Entourage Effect.” The products offered by Surterra Wellness are formulated to leverage the combined benefits of CBD, THC, and terpenes to deliver targeted effects.
CBD
THC
TERPENES
6
Surterra | Cannabis and Medical Marijuana
CBD
THC
TERPENES


The Surterra Wellness Process
Surterra Wellness extracts therapeutic cannabinoids and naturally-derived terpenes, and recombines them into targeted formulations, enabling safe and consistent products. Each product is formulated with a unique terpene profile.
Effect-Specific
• A fractional distillation system separates the cannabinoids and naturally-derived terpenes from each plant.
• The Cannabinoids and Terpenes are recombined toachieve effectspecific formulations.
• The resulting product is 90% + pure refined oils.
Calm 12.5 : 1
Serene 5 : 1
Soothe 1 : 1
Zen 1 : 4
Relief 1 : 9
REVIVEAM 1 : 1
RELAXPM 1 : 9
All Surterra Wellness products are tested by third-party labs to certify purity and the absence of residual toxins.
Surterra | Cannabis and Medical Marijuana 7
Cannabis and Medical Marijuana


Clinical Pharmacology
(The following pharmaceutical profile relates to all products.)
The Mechanism of Action of THC is complex and not yet completely understood but is believed to interact with the CB1 and CB2 cannabinoid receptors and may also target opioid and benzodiazepine receptors. CBD is believed to affect the CB1 and CB2 receptors more indirectly through calcium channels, potassium channels, and possibly other electrolyte channels.
THC is rapidly absorbed through inhalation and the extent of which depends on depth of inhalation, lung volume, and exposure time. Through inhalation, peak plasma concentrations may be attained within a few minutes of inhalation. Oral ingestion is much slower compared to inhalation and peak plasma concentrations may be attained within 2 hours. The complexity of metabolism of THC is further complicated because the chemical changes that occur after smoking the plant are different than the changes that occur after ingesting the plant.
THC is metabolized by the liver through interaction with the CYP3A4 and CYP2C9 enzymes. CBD is metabolized through the CYP450 system, specifically interacting with the CYP3A4 and CYP2C19 enzymes. Special consideration should be taken when recommending cannabis products in treatment of patients who are also taking medications that are metabolized through the CYP450 system or who have disease states affecting the normal function of the liver and kidney.3
THC is eliminated through the urine and feces and, depending on the frequency of use, may be detectable in the body up to 25 days in chronic users and as little as 3 days among infrequent users. Half-life can vary from 1.3 days in infrequent users and up to 13 days in frequent users.4
8 Surterra | Pharmacology and Dosing


Contraindications:
• Acute psychosis and other unstable psychiatric conditions
• History of hypersensitivity to Cannabis, THC, CBD, Terpenes,
or any of the components of Surterra products
Side Effects:
• Anxiety, Dizziness, Dry Mouth, Dysphoria, High Blood Pressure, Impaired Motor Skills, Rapid heart rate, Sedation
• Chronic use may lead to Cannabis Hyperemesis Syndrome
(CHS)
• Products that have higher THC content may elicit
psychoactive responses during use.
Some side effects of THC could include:
• Heightened senses • Irritability
• Mood-swings
• Paranoia
Cautions:
Caution should be exercised when recommending to patients with the following conditions:
• Cardiac Arrhythmia
• Cardiovascular disease
• Liver disease
• Kidney disease
Special considerations:
• Pregnancy: Marijuana has not been proven safe during pregnancy.
• Breast-feeding: Marijuana is likely unsafe during breast feeding. THC is found 6 days post consumption in breast milk.5
• Using cannabis with alcohol may increase intoxicating effects.
Medications to monitor during
combined use: This list is not comprehensive. • Anti-epileptics
• Clobazam
• Immunotherapies
These statements have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease.
• Theophylline • Valproic Acid • Warfarin
Surterra | Pharmacology and Dosing
9
Pharmacology and Dosing


Dosing
Patient Titration and Tolerance:
• In general, there are no absolutes when recommending medical cannabis. Practitioners and patients have the freedom to titrate the medication dosing and route of administration to meet individual needs. Finding the right dose will require some trial and error as dosing is dependent on individual body composition and metabolism. New users should start low and go slow and keep a medication journal to assist in finding the right product, dosage and route of administration that works best.
• When choosing the right product for your patient, take into consideration: - Qualifying condition
- Prior cannabis experience
- Product total cannabinoid content, CBD and THC ratio
- Product terpene profile
- Product route of administration, onset and duration
• For patients wishing to avoid a mood-altering experience, it is recommended that they start with a high CBD product like
Calm or Serene.
• For patients with prior cannabis experience, their tolerance for THC may be higher and starting with a stronger dose of
THC may be needed to achieve the desired effect.
See individual product description for specific dosing information.
10 Surterra | Pharmacology and Dosing


Converting Inhalations to Tincture Oil
Tincture Oil
Total Cannabinoid Dosage
Vape Pen
Route of Administration
Vape
Oral Tincture Oil 10 mg/ml
Oral Tincture Oil 20 mg/ml
Oral Tincture Oil 45 mg/ml
Desired Dosage
one, 2-second draw ~ 2.5 mg
10 mg/ml
10 mg/40 drops
20 mg/ml
20 mg/40 drops
45 mg/ml
45 mg/40 drops
2.5 mg dose
1 vape inhalation
0.25 ml
10 drops
0.125 ml
5 drops
n/a
n/a
5 mg dose
2 vape inhalations
0.5 ml
20 drops
0.25 ml
10 drops
n/a
n/a
10 mg dose
4 vape inhalations
1 ml
40 drops
0.5 ml
20 drops
~0.2 ml
9 drops
20 mg dose
8 vape inhalations
2 ml
2 full droppers
1 ml
40 drops
~0.45 ml
18 drops
40 mg dose
16 vape inhalations
4 ml
4 full droppers
2 ml
2 full droppers
~0.9 ml
36 drops
45 mg dose
18 vape inhalations
4.5 ml
4 full droppers plus 20 drops
2.25 ml
2 full droppers plus 10 drops
~1 ml
40 drops
Surterra | Pharmacology and Dosing
11
Pharmacology and Dosing


Recommended Use
Topical Lotion: Apply lotion liberally to the affected area. Lotion is best used to address localized pain and inflammation in muscles or joints.Lotions that contain THC provide local pain relief without the intoxicating effects. Avoid contact with eyes or mucus membranes.
Vape Pen Inhalation: Use a vape pen for inhalation when you want immediate results. The vape pen offers rapid onset of systemic effects and the effects of the medication begin to fade after a couple of hours. Place the pen to your lips, inhale for 2 seconds and then exhale the vaporized medication. Some coughing may occur. Use caution in patients with respiratory conditions.
Oral Tincture Oils: Use oral tincture oils to obtain
effects that are quick and long lasting. Oral tincture oils may be placed sublingually to obtain a quick onset and then swallow the remaining dose for a longer lasting effect. The initial absorption through the mucus membranes will offer an initial onset that begins within 30 minutes while the digested portion will begin taking effect in about 60 minutes, providing a longer lasting effect that may last up to 6 hours.
TheraGels: TheraGels are easy to swallow soft gels, are digested quickly and begin taking effect in 30 minutes. TheraGels are recommended for patients seeking a longer lasting medication through a more traditional route of administration.
Pure Reserve Oil: The Pure Reserve Oil is a concentrated medication in a viscous oil and is intended to deliver the strongest dose of medication. Before taking a product in the form of the Pure Reserve Oil, it is advised to test results with smaller doses in a vape or tincture oil to best understand how the patient will respond to the medication. Warm the syringe in a cup of warm water for 5 minutes before removing the
cap from the syringe, place the desired dose along the gum line and let it dissolve in the mouth. Pure Reserve Oil begins to take effect within an hour and may last up to 8 hours.
Transdermal Patch: The transdermal patch will provide a low level of medication over a period of up to 12 hours. Place the patch on skin cleansed with alcohol and away from areas that may interfere with clothing such as waist bands or straps. Patches that contain THC are reported to provide pain relief without the intoxicating effects.
Medication routes of administration may be paired together to obtain the desired effect. For example, TheraGels may be paired with a vape pen. The vape pen provides immediate relief and tapers off in a couple hours, while the TheraGels begins taking effect in the first hour and may provide long lasting medication effects up to 6 hours.
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Surterra | Pharmacology and Dosing


Route of
Administration
Route of Administration
Topical Lotion
Vape Pen Inhalation
Oral Tincture Oils
TheraGels
Pure Reserve Oil
Transdermal Patch
Onset of Action
Immediate
2-5 minutes
30 minutes
30-60 minutes
45 minutes
30-90 minutes
Duration
2-12 hours
1-4 hours
2-6 hours
4-6 hours
6-8 hours
8-12 hours
Relative Effect Over Time
by Intake Method
0 1 2 3 4 5 6 7 8 9 10 11 12
Time After Dosing (Hrs)
Graph is a visual representation of a single dose and relative effect over time.
Surterra | Pharmacology and Dosing 13
Vape Pen
Tincture Oil TheraGels Transdermal Patch
Relative Effect
Pharmacology and Dosing


Dosing Your Patients
Suggested Product Use
To determine which product is best for your patients, consider two things:
1.
Patient Tolerance
For patients with little to no cannabis experience, start with the lowest strength within the recommended product line(s).
For cannabis-experienced patients, start with the lowest strength in the most psychoactive product line recommended for their condition.
2. Desired Psychoactivity
For patients who do not desire a psychoactive efect, it is recommended to start with a CBD-weighted product. For patients who desire a psychoactive e fect, it is recommended to use a balanced or THC-weighted product line.
Multiple Sclerosis Glaucoma
Chronic Nonmalignant Pain ALS
HIV Cancer
AIDS Crohn’s 20mg
10mg 20mg
CBD=4 THC=16
CBD=1 THC=9
CBD=2 THC=18
PTSD Parkinson’s
45mg CBD = 22.5 20mg THC = 22.5
CBD=10 THC=10
10mg CBD = 2
CBD = 18.5 THC = 1.5
Epilepsy
45mg CBD = 41.7 THC = 3.3
45mg
20mg
CBD = 16.7 THC = 3.3
10mg CBD=5
C M Y CM MY CY CMY K
20mg
CBD=37.5 THC=7.5
THC=8
THC=5
CALM
12.5CBD:1THC
*PRO available only in 90mg
*PRO available only in 90mg
*Lotion available only in 12mg
*PRO available only in 90mg
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Surterra | Family of Products: Surterra Wellness
SERENE
5CBD:1THC
SOOTHE
1CBD:1THC
ZEN
1CBD:4THC
RELIEF
1CBD:9THC
PSYCHOACTIVITY


Product Lotion Vape Oral Tincture Oral Tincture Oral Tincture TheraGels Pure Reserve Transdermal Family Oil — 10 mg/ml Oil — 20 mg/ml Oil — 45 mg/ml Oil — 90 mg Patch
Calm 12.5 : 1 CBD:THC
Soothe 1 : 1 CBD:THC
Relief 1 : 9 CBD:THC
—
RelaxPM 1:9 CBD:THC
—
1 pump ~ 2.4 mg
—
—
20 mg per patch
one, 2-second draw ~ 2.5 mg
10 mg/ml
Serene 5 : 1 CBD:THC
Zen 1 : 4 CBD:THC
ReviveAM 1:1 CBD:THC
——
—
—
—
*Calm TheraGels ratios are 9 : 1, unlike other Calm products (12.5 : 1)
**Serene TheraGels ratios are 4 : 1, unlike other Serene products (5 : 1)
Desired 1 pump
10 mg per
Dosage ~ 2.4 mg
TheraGel
Lotion
Vape
one, 2-second draw ~ 2.5 mg
Oral Tincture Oil — 10 mg/ml
10 mg/ml
Oral Tincture Oil — 20 mg/ml
20 mg/ml
Oral Tincture Oil — 45 mg/ml
45 mg/ml 0.2 ml
TheraGels
Pure Reserve Oil — 90 mg
0.05 ml = 45 mg N/A
Transdermal Patch
20 mg per patch N/A
Surterra | Family of Products: Surterra Wellness
15
10 mg dose 4 pumps 4 vape inhalations 1 ml 0.5 ml
1 TheraGel
—
20 mg/ml
—
—
45 mg/ml
—
—
—
10 mg
—
—
90 mg
—
—
—
—
Family of Products: Surterra Wellness


Calm 12.5 : 1 CBD:THC
The Calm product line utilizes a combination of THC, CBD and terpenes that promote relaxation. Terpenes b-Myrcene and Linalool help reduce spasms and seizures, while decreasing anxiety.
Terpene Profile
Linalool d-Limonene
b-Myrcene b-Caryophyllene
a-Pinene
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Surterra | Calm 12.5 : 1


Calm Vape Pen
Calm Oral Tincture Oil 20 mg/ml
Calm 12.5 : 1
Dosage
CBD:THC
Single Dose
one, 2 sec draw ~ 2.5 mg
2.3 mg : 0.2 mg
Calm 12.5 : 1
Dosage
CBD:THC
Concentration
20 mg/ml
18.5 mg : 1.5 mg
Calm TheraGels
Calm Oral Tincture Oil 45 mg/ml
Calm* 9 : 1
Dosage
CBD:THC
Single Dose
1 TheraGel = 10 mg
9 mg : 1 mg
Calm 12.5 : 1
Dosage
CBD:THC
Concentration
45 mg/ml
41.7 mg : 3.3 mg
* Calm TheraGel ratios are 9:1, diferent than the other Calm products (12.5 : 1)
Calm Pure Reserve Oil
Calm Transdermal Patch
Calm 12.5 : 1
Dosage
CBD:THC
Single Dose
0.05 ml = 45 mg
41.6 mg : 3.4 mg
Calm Lotion
Calm 12.5 : 1
Dosage
CBD:THC
Single Dose
20 mg per patch
18.5 mg : 1.5 mg
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene Eucalyptol2 Humulene d-Limonene Linalool b-Myrcene a-Pinene Terpineol
Black pepper, cloves Eucalyptus, rosemary, ginger Cloves, basil, hops
Fruit rinds, peppermint Lavender, citrus
Mango, lemongrass, thyme Pine needles, rosemary, dill Lilac, pine trees, lime blossoms
Anti-inlammatory, improved sleep Anti-fungal, anti-inlammatory Anti-bacterial, anti-inlammatory Anxiety relief, stress relief Calming, sedation
Relaxation, sedation Alertness, memory Calming, sedation
Calm 12.5 : 1
Dosage
CBD:THC
Single Dose
1 pump ~ 2.4 mg
2.2 mg : 0.2 mg
Surterra | Calm 12.5 : 1
17
Calm 12.5 : 1


Serene 5 : 1 CBD:THC
The Serene product line is formulated with a terpene profile that includes b-Myrcene, d-Limonene and Linalool to enhance mood and assist in the treatment of stress-related ailments.
Terpene Profile
Linalool d-Limonene
b-Myrcene b-Caryophyllene
a-Pinene Eucalyptol
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Surterra | Serene 5 : 1


Serene Vape Pen
Serene Oral Tincture Oil 20 mg/ml
Serene 5 : 1
Dosage
CBD:THC
Single Dose
one, 2 sec draw ~ 2.5 mg
2.1 mg : 0.4 mg
Serene 5 : 1
Dosage
CBD:THC
Concentration
20 mg/ml
16.7 mg : 3.3 mg
Serene TheraGels
Serene Oral Tincture Oil 45 mg/ml
Serene* 4 : 1
Dosage
CBD:THC
Single Dose
1 TheraGel = 10 mg
8 mg : 2 mg
Serene 5 : 1
Dosage
CBD:THC
Concentration
45 mg/ml
37.5 mg :7.5 mg
*Serene TheraGel ratios are 4:1, diferent than the other Serene products (5 : 1)
Serene Pure Reserve Oil
Serene Transdermal Patch
Serene 5 : 1
Dosage
CBD:THC
Single Dose
0.05 ml = 45 mg
37.5 mg : 7.5 mg
Serene 5 : 1
Dosage
CBD:THC
Single Dose
20 mg per patch
16.7 mg : 3.3 mg
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene Eucalyptol2 Humulene d-Limonene Linalool b-Myrcene a-Pinene Terpineol
Black pepper, cloves Eucalyptus, rosemary, ginger Cloves, basil, hops
Fruit rinds, peppermint Lavender, citrus
Mango, lemongrass, thyme Pine needles, rosemary, dill Lilac, pine trees, lime blossoms
Anti-inlammatory, improved sleep Anti-fungal, anti-inlammatory Anti-bacterial, anti-inlammatory Anxiety relief, stress relief Calming, sedation
Relaxation, sedation Alertness, memory Calming, sedation
Surterra | Serene 5 : 1
19
Serene5:1


Soothe 1 : 1 CBD:THC
The Soothe product line is formulated for balance and includes terpenes b-Caryophyllene and d-Limonene to balance stress relief and pain management.
Terpene Profile
Linalool d-Limonene
b-Myrcene b-Caryophyllene
a-Pinene Terpineol
20
Surterra | Soothe 1 : 1


Soothe Vape Pen
Soothe Oral Tincture Oil 10 mg/ml
Soothe 1 : 1
Dosage
CBD:THC
Single Dose
one, 2 sec draw ~ 2.5 mg
1.25mg : 1.25mg
Soothe 1 : 1
Dosage
Concentration
10 mg/ml
Soothe TheraGels
Soothe Oral Tincture Oil 20 mg/ml
Soothe 1 : 1
Dosage
CBD:THC
Single Dose
1 TheraGel = 10 mg
5 mg : 5 mg
Soothe 1 : 1
Dosage
CBD:THC
Concentration
20 mg/ml
10 mg : 10mg
Soothe 1 : 1
Dosage
CBD:THC
Single Dose
0.05 ml = 45 mg
22.5 mg : 22.5 mg
Soothe Transdermal Patch
CBD:THC
5 mg : 5 mg
Soothe Oral Tincture Oil 45 mg/ml
Soothe Pure Reserve Oil
Soothe 1 : 1
Dosage
CBD:THC
Concentration
45 mg/ml
22.5 mg : 22.5 mg
Soothe Lotion
Soothe 1 : 1
Dosage
CBD:THC
Single Dose
20 mg per patch
10 mg : 10 mg
Soothe 1 : 1
Dosage
CBD:THC
Single Dose
1 pump ~ 2.4 mg
1.2 mg : 1.2 mg
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene Eucalyptol2 Humulene d-Limonene Linalool b-Myrcene a-Pinene Terpineol
Black pepper, cloves
Eucalyptus, rosemary, ginger Cloves, basil, hops
Fruit rinds, peppermint
Lavender, citrus
Mango, lemongrass, thyme
Pine needles, rosemary, dill 21 Lilac, pine trees, lime blossoms
Anti-inlammatory, improved sleep Anti-fungal, anti-inlammatory Anti-bacterial, anti-inlammatory Anxiety relief, stress relief Calming, sedation
Relaxation, sedation Alertness, memory Calming, sedation
Surterra | Soothe 1 : 1
Soothe1:1


Zen 1 : 4 CBD:THC
The Zen product line is a THC-dominant formula created to alleviate stress and discomfort. D-Limonene and b-Myrcene boost the Zen family line with anti- inflammatory properties perfect for pain relief.
Terpene Profile Linalool
d-Limonene Geraniol
b-Myrcene b-Caryophyllene
a-Pinene Humulene
22
Surterra | Zen 1 : 4


Zen Vape Pen
Zen Oral Tincture Oil 10 mg/ml
Zen 1 : 4
Dosage
CBD:THC
Single Dose
one, 2 sec draw ~ 2.5 mg
0.5 mg : 2 mg
Zen 1 : 4
Dosage
CBD:THC
Concentration
10mg/ml
2 mg : 8 mg
Zen TheraGels
Zen Oral Tincture Oil 20 mg/ml
Zen 1 : 4
Dosage
CBD:THC
Single Dose
1 TheraGel = 10 mg
2 mg : 8 mg
Zen 1 : 4
Dosage
CBD:THC
Concentration
20 mg/ml
4 mg : 16 mg
Zen Pure Reserve Oil
Zen Transdermal Patch
Zen 1 : 4
Dosage
CBD:THC
Single Dose
0.05 ml = 45 mg
9 mg : 36 mg
Zen 1 : 4
Dosage
CBD:THC
Single Dose
20 mg per patch
4 mg : 16 mg
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene Eucalyptol2 Humulene d-Limonene Linalool b-Myrcene a-Pinene Terpineol
Black pepper, cloves Eucalyptus, rosemary, ginger Cloves, basil, hops
Fruit rinds, peppermint Lavender, citrus
Mango, lemongrass, thyme Pine needles, rosemary, dill Lilac, pine trees, lime blossoms
Anti-inlammatory, improved sleep Anti-fungal, anti-inlammatory Anti-bacterial, anti-inlammatory Anxiety relief, stress relief Calming, sedation
Relaxation, sedation Alertness, memory Calming, sedation
Surterra | Zen 1 : 4
23
Zen1:4


Relief 1 : 9 CBD:THC
The Relief product line targets acute conditions and troublesome pain to help restore mood and well- being. B-Myrcene helps reduce anxiety and minimize deep discomfort.
Terpene Profile
Linalool d-Limonene
b-Myrcene b-Caryophyllene
a-Pinene Humulene
24
Surterra | Relief 1 : 9


Relief Vape Pen
Relief Oral Tincture Oil 10 mg/ml
Relief 1 : 9
Dosage
CBD:THC
Single Dose
one, 2 sec draw ~ 2.5 mg
0.25 mg : 2.25 mg
Relief 1 : 9
Dosage
CBD:THC
Concentration
10mg/ml
1 mg : 9 mg
Relief TheraGels
Relief Oral Tincture Oil 20 mg/ml
Relief 1 : 9
Dosage
CBD:THC
Single Dose
1 TheraGel = 10 mg
1 mg : 9 mg
Relief 1 : 9
Dosage
CBD:THC
Concentration
20 mg/ml
2 mg : 18 mg
Relief Pure Reserve Oil
Relief Transdermal Patch
Relief 1 : 9
Dosage
Single Dose
0.05 ml = 45 mg
Relief 1 : 9
Dosage
Single Dose
20 mg per patch
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene Eucalyptol2 Humulene d-Limonene Linalool b-Myrcene a-Pinene Terpineol
Black pepper, cloves Eucalyptus, rosemary, ginger Cloves, basil, hops
Fruit rinds, peppermint Lavender, citrus
Mango, lemongrass, thyme Pine needles, rosemary, dill Lilac, pine trees, lime blossoms
Anti-inlammatory, improved sleep Anti-fungal, anti-inlammatory Anti-bacterial, anti-inlammatory Anxiety relief, stress relief Calming, sedation
Relaxation, sedation Alertness, memory Calming, sedation
Surterra | Relief 1 : 9
25
CBD:THC
2 mg : 18 mg
CBD:THC
4.5 mg : 40.5 mg
Relief1:9


REVIVEAM1:1
REVIVEAM daytime formula contains a balanced formula that gives patients a boost in their day while helping them with pain management. Each REVIVEAM pen contains 115 mg of CBD and 115mg of THC, plus a blend of terpenes to offer an uplifting experience without grogginess or sedation.
Terpene Profile
Linalool d-Limonene
b-Myrcene b-Caryophyllene
a-Pinene Terpineol
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene Eucalyptol2 Humulene d-Limonene Linalool b-Myrcene a-Pinene Terpineol
Black pepper, cloves Eucalyptus, rosemary, ginger Cloves, basil, hops
Fruit rinds, peppermint Lavender, citrus
Mango, lemongrass, thyme Pine needles, rosemary, dill Lilac, pine trees, lime blossoms
Anti-inlammatory, improved sleep Anti-fungal, anti-inlammatory Anti-bacterial, anti-inlammatory Anxiety relief, stress relief Calming, sedation
Relaxation, sedation Alertness, memory Calming, sedation
26
Surterra | ReviveAM 1 : 1


RELAXPM1:9
RELAXPM nighttime formula helps patients wind down and fall into a restorative sleep. Each RELAXPM pen contains 23mgofCBDand207mgof THC plus a blend of terpenes to offer a relaxing experience that promotes a good night’s rest.
Terpene Profile
Linalool d-Limonene
b-Myrcene b-Caryophyllene
a-Pinene Humulene
Cannabis Terpene1 Also found in: Potential effects:
b-Caryophyllene Eucalyptol2 Humulene d-Limonene Linalool b-Myrcene a-Pinene Terpineol
Black pepper, cloves Eucalyptus, rosemary, ginger Cloves, basil, hops
Fruit rinds, peppermint Lavender, citrus
Mango, lemongrass, thyme Pine needles, rosemary, dill Lilac, pine trees, lime blossoms
Anti-inlammatory, improved sleep Anti-fungal, anti-inlammatory Anti-bacterial, anti-inlammatory Anxiety relief, stress relief Calming, sedation
Relaxation, sedation Alertness, memory Calming, sedation
Surterra | RelaxPM 1 : 9
27
REVIVEAM 1 : 1 RELAXPM 1 : 9


Ingredients
Lotion: Cannabis Oil, Medium-chain Triglyceride Oil (MCT oil), Natural Eucalyptus, Natural Lavender,
Lotion Base (Water, Sunflower Seed Oil, Polysorbate 20, Cetearyl Alcohol, Glyceryl Stearate, Phenoxyethanol, Carbomer, Potassium Sorbate, Sodium Hydroxide)
Vape Pen: Cannabis Oil, Naturally-derived Terpenes
Oral Tincture Oil: Cannabis Oil, Naturally-derived Terpenes, MCT Oil, and natural flavorings Natural flavorings specific to each product:
Calm: natural almond and mint extracts
Serene: natural almond extracts
Soothe: natural blueberry and almond extracts Zen: natural Florida orange extracts
Relief: natural Florida orange extracts
TheraGels: Cannabis Oil, Mct Oil, Naturally-derived Terpenes, Bovine Gelatin Pure Reserve Oil: Cannabis Oil, Naturally-derived Terpenes
Transdermal Patch: Cannabis Oil, Naturally-derived Terpenes, Oleic Acid, Menthol, Camphor and Light Mineral Oil. Latex free.
28 Surterra | Ingredients / Safety Measures


Medicinal Marijuana Safety Measures
• Florida Laws: Medical marijuana is available in Florida but marijuana is illegal under federal law. The laws for medical marijuana do vary state-to-state and should be considered before carrying medication across state lines.
• Use caution when driving a motorized vehicle while taking medication. Medical marijuana may impair judgement and alter reaction time. Driving intoxicated is never allowed.
• Keep medication in a secure and locked container to prevent children or pets from accidental consumption.
• Always keep medication with original labeling and packaging. Under Florida medical marijuana laws, sharing medication with others is not allowed.
Surterra | Ingredients / Safety Measures 29
Ingredients / Safety Measures


Qualifying Conditions6
Cannabis is indicated for use for the qualifying conditions identified by the Florida department of health:
1. Cancer
2. Epilepsy 3. Glaucoma 4. HIV
5. AIDS
6. Post-Traumatic Stress disorder (PTSD
7. Amyotrophic Lateral Sclerosis (ALS)
8. Crohn’s disease
9. Parkinson’s disease 10. Multiple Sclerosis (MS)
11. Medical conditions of the same kind or class as or comparable to conditions 1-10.
12. A terminal condition diagnosed by a physician other than the qualified physician issuing the physician certification
13. Chronic nonmalignant pain caused by a qualifying medical condition or that originates from a qualifying medical condition and persists beyond the usual course of the qualifying medical condition.
3 0 Surterra | Ingredients / Safety Measures


Cited References:
1. Rahn,Bailey,Cannabis101:WhatAreCannabisTerpenesandWhat
Do They Do? https://www.leafly.com posted April 2018.
2. Colbert,Mitchell,TerpeneProfile:Eucalyptol. PostedonTheLeaf Online, November 2014. Weblink: http://theleafonline.com/c/ science/2014/11/terpene-profile-eucalyptol/
3. Horn,J.andHansten,P,DrugInteractionswithMarijuana, December 2014. Weblink: https://www.pharmacytimes.com/ publications/issue/2014/december2014/drug-interactions-with- marijuana
4. Priyamvadaetal,IranJournalofPsychiatry,2012Fall,Chemistry, Metabolism, and Toxicology of Cannabis: Clinical Implications. Weblink: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570572/
5. Bertrandetal,Pediatrics,2018Sept:142(3),MarijuanaUseby Breastfeeding Mothers and Cannabinoid Concentrations in Breast Milk. Weblink: https://www.ncbi.nlm.nih.gov/pubmed/30150212
6. Florida Department of Health Patient Guide and Qualifying Conditions: March 2018, Weblink: http://www.floridahealth.gov/ programs-and-services/office-of-medical-marijuana-use/patients/ index.html
Other Resources:
•Geffrey,A.L.,Pollack,S.F.,Bruno,P.L.,andThiele,E.A.EpilepsiaAugust 2015, Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy. Weblink: https://www.ncbi.nlm.nih. gov/pubmed/26114620
• Grayson, L., Vines, B., Nichol, K., and Szaflarski, J. Epilepsy and Behavior Case Reports, An Interaction between Warfarin and Cannabidiol, a case report. Weblink: https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5789126/
• Hartman, R.L., Brown, T.L., Milavetz, G., Spurgin, A., Pierce, R.S., Gpre;ocl. D.A., Gaffney, G., and Huestis, M.A. Journal of Drug and Alcohol Dependency, 2015 September, Cannabis effects on driving lateral control with and without alcohol. Weblink: https://www.ncbi. nlm.nih.gov/pubmed/26144593
• Iffland, K and Grotenhermen, F, Cannabis and Cannabinoid Research, 2017;2(1):139–154. AnUpdateonSafetyandSideEffectsof Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Weblink: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
• Stout, S.M. and Cimino, N.M. Drug Metabolism Reviews Feb 2014, Exogenous cannabinoids as substrates, inhibitors, and iducers of human drug metabolizing enzymes: a systematic review. Weblink: https://www.ncbi.nlm.nih.gov/pubmed/24160757
Surterra | Ingredients / Safety Measures
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Ingredients / Safety Measures


NOTES




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